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Demirturk Orhan Saim - - 2012
PURPOSE: We aimed to describe the long-term outcome of endovascular treatment of iliofemoral deep vein thrombosis in the postpartum period. MATERIALS AND METHODS: Between 2002 and 2010, 18 consecutive female patients with acute or subacute iliofemoral deep vein thrombosis in the postpartum period who had endovascular treatment were retrospectively evaluated. ...
Xu Ruoyan R Institute of Integrative Biology, Department of Chemical and Structural Biology, University of Liverpool, Crown Street, Liverpool L69 7ZB, United - - 2012
The functions of a large number (>435) of extracellular regulatory proteins are controlled by their interactions with heparan sulfate (HS). In the case of fibroblast growth factors (FGFs), HS binding determines their transport between cells and is required for the assembly of high affinity signaling complexes with their cognate FGF ...
Shigematsu Kazuo - - 2012
BACKGROUND: To predict the outcome of stroke at an acute stage is important but still difficult. Vomiting is one of the commonest symptoms in stroke patients. The aim of this study is threefold: first, to examine the percentage of vomiting in each of the three major categories of strokes; second, ...
Traa Marjan Johanna - - 2012
Introduction.  Even though the body of literature on sexual functioning is growing, information on the preoperative sexual functioning and the quality of sexual life after colorectal cancer is lacking. Research focusing on female patients and on partners is also rather scarce. Aim.  This cross-sectional study aimed to describe the preoperative ...
Picchi Jacopo - - 2012
Human stromal stem cell populations reside in different tissues and anatomical sites, however a critical question related to their efficient use in regenerative medicine is whether they exhibit equivalent biological properties. Here, we compared cellular and molecular characteristics of stromal stem cells derived from the bone marrow, at different body ...
Zhang Taylor - - 2012
We describe here the identification of a stop codon TAA (Stop) → GAA (Glu) = Stop221E mutation on the light chain of a recombinant IgG1 antibody expressed in a Chinese hamster ovary (CHO) cell line. The extended light chain variants, which were caused by translation beyond the mutated stop codon ...
Celebrano Michele - - 2012
We demonstrate the ability to trap, levitate and orient single anisometric nanoscale objects with high angular precision in a fluid. An electrostatic fluidic trap confines a spherical object at a spatial location defined by the minimum of the electrostatic system free energy. For an anisometric object and a potential well ...
Islam Mohammad Aminul - - 2012
The purpose of the study was to screen for reduced susceptibility against imipenem and the presence of the New-Delhi Metallo-β-lactamase-1 (NDM-1) gene in a collection of Enterobacteriaceae (E. coli, Shigella spp. and Klebsiella pneumoniae) from different surveillance studies between 2003 and 2010 at the International Centre for Diarrhoeal Disease Research, ...
Shinde K N - - 2012
A series of efficient Li(3) Al(2) (PO(4) )(3) :Eu(2+) novel phosphors were synthesized by the facile combustion method. The effects of dopant on the luminescence behavior of Li(3) Al(2) (PO(4) )(3) phosphor were also investigated. The phosphors were characterized by X-ray diffraction, field emission scanning electron microscope and photoluminescence techniques. ...
Schmidt Signe - - 2012
Abstract Background: This follow-up study investigates the metabolic and psychosocial effects of sensor-augmented pump (SAP) therapy in adults with type 1 diabetes 36 months after therapy start. Subjects and Methods: We invited all 24 Danish adults with type 1 diabetes who had previously participated in the European multicenter randomized controlled ...
Leroux Frédéric R - - 2012
A modular way towards biaryls: Highly enantioenriched biphenyls can be prepared based on a transition-metal-free aryl-aryl coupling followed by efficient desymmetrization or deracemization and chemoselective functionalization.
Janas Maja M - - 2012
MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally regulate protein output from the majority of human mRNAs. In contrast to the consensus view that all miRNAs are associated with Argonaute (Ago) proteins, we determine that miRNAs are expressed in a 13-fold excess relative to Agos in HeLa cells and that ...
Murphy Niamh - - 2012
The P2X(7) receptor is an ion-gated channel which is activated by high extracellular concentrations of adenosine triphosphate (ATP). Activation of P2X(7) receptors has been shown to induce neuroinflammatory changes associated with several neurological conditions. The matrix metalloproteinases (MMPs) are a family of endopeptidases that have several functions including degradation of ...
He Xiaoxiao - - 2012
Fluorescent dye-doped silica nanoparticles are increasingly used for in vivo imaging due to their unique biocompatibility and easy surface modification. However, the utility of existing fluorescent dye-doped silica nanoparticles for in vivo imaging is still limited because most of studies are focused on doping single near-infrared (NIR) dyes in the ...
Mathews Marlon S MS Department of Neurosurgery, University of California, Irvine, California, USA. - - 2012
One of many limitations for cancer gene therapy is the inability of the therapeutic gene to transfect a sufficient number of tumor cells. Photochemical internalization (PCI) is a photodynamic therapy-based approach for improving the delivery of macromolecules and genes into the cell cytosol. The utility of PCI for the delivery ...
Thomas Joseph Palathinkal - - 2012
The design and fabrication of well-defined nanostructures have great importance in nanoelectronics. Here we report the precise growth of sub-2 nm (c-diamond) and above 5 nm (n-diamond) size diamond grains from energetic species (chemical vapor deposition process) at low growth temperature of about 460 oC. We demonstrate that a pre-nucleation ...
Benson Jonas S - - 2012
Introduction.  Microdenervation of the spermatic cord (MDSC) has been demonstrated to be an effective treatment for men with intractable scrotal content pain. Aim.  This study evaluates the correlation between a positive response to a spermatic cord block with local anesthetic and the subsequent surgical outcome following MDSC. Main Outcome Measures.  ...
Shang Yang - - 2012
Cutting edge: A Cu(2) O jagged polyhedron, with numerous {110} edges and {111} corners, has been developed through a top-down selective oxidative etching process at the expense of the original {111} facet. The as-prepared nanocrystals exhibited higher photocatalytic activities for the degradation of methylene orange, which may be primarily ascribed ...
Wei Chun-Ling - - 2012
The efficiency of neural circuits is modified by changes not only in synaptic strength, but also in intrinsic excitability of neurons. In CA1 hippocampal pyramidal neurons, bidirectional changes in the intrinsic excitability are often presented after induction of synaptic long-term potentiation or depression. This plasticity of intrinsic excitability has been ...
van Velzen Jeroen F - - 2012
BACKGROUND: Multicolor flow cytometry (MFC) is increasingly important for the diagnosis and minimal residual disease (MRD) assessment of patients with plasma cells (PC) dyscrasias, like multiple myeloma. Recently published information shows that immunophenotype of myeloma PC can change over time and normal PC are heterogeneous in the expression of CD19 ...
Gorkin David U - - 2012
We take a comprehensive approach to the study of regulatory control of gene expression in melanocytes that proceeds from large-scale enhancer discovery facilitated by ChIP-seq; to rigorous validation in silico, in vitro, and in vivo; and finally to the use of machine learning to elucidate a regulatory vocabulary with genome-wide ...
Castiñeiras Alfonso - - 2012
Octahedral 1 : 1 Ni(II) and square-planar 1 : 1 Pd(II) and Pt(II) complexes of formulae [Ni(HAcb4DM)(AcO)(H(2)O)(2)]·H(2)O (), [Pd(HAcb4DM)Cl]·5H(2)O () and [Pt(HAcb4DM)Cl]·3H(2)O (), where H(2)Acb4DM = 5-acetylbarbituric-4N-dimethylthiosemicarbazone (H(2) denoting its two dissociable protons, one enolic and one thiolic), have been synthesized and characterized by elemental analysis and by (1)H and (13)C NMR, UV-vis, and ...
Goryu Akihiro - - 2012
Nanoscale devices have the potential to measure biological tissues as well as individual cells/neurons. However, three-dimensional (3D) multi-site probing remains problematic because only planar-type device designs are applicable to sample surfaces. Herein we report 3D nanoscale electrode tipped microwire arrays with high aspect ratios. A nanoscale tipped wire is formed ...
Dale William - - 2012
To determine whether recent experience and specialty choice would affect physician adherence to evidence-based guidelines. In a series of computer-simulated encounters, participants weighed the risk of spontaneous abdominal aortic aneurysm (AAA) rupture against the risk of perioperative death to determine timing for elective repair. Guideline recommendations and statistical information on ...
Becce Fabio - - 2012
PURPOSE: To assess the value of adding axial traction to direct MR arthrography of the shoulder, in terms of subacromial and glenohumeral joint space widths, and coverage of the superior labrum-biceps tendon complex and articular cartilage by contrast material. MATERIALS AND METHODS: Twenty-one patients investigated by direct MR arthrography of ...
Wang Fei-Fei - - 2012
A new phenolate-based magnesium ion conducting electrolyte is prepared. The electrolyte exhibits air insensitive character and excellent electrochemical performances which make it highly promising for advanced rechargeable Mg battery systems.
Wu Yu-Ching YC Institute of Zoology, College of Life Science, National Taiwan University, Taipei 10673, - - 2012
Bves is widely observed in the cell junction of the skin, epicardium, intestine, and cornea of both developmental embryos and mature adults. However, it is not clear how Bves confers its role in intercellular adhesion. Here, we identified the zebrafish bves (zBves) and found that the epidermal barrier function could ...
Mor Zohar - - 2012
Childhood tuberculosis (CT) poses high-risk for morbidity and death. This study describes CT characteristics in Israel and examines treatment outcomes.Data sources were the National Tuberculosis Registry and the National Civil-Census.Between 1999 and 2010, 416 children (<18 years) had CT, averaging 1.5 per 100,000 children (range: 0.6-3.2) demonstrating a declining trend. ...
Villars C - - 2012
Combining accelerometry (ACC) with heart rate (HR) monitoring is thought to improve activity energy expenditure (AEE) estimations compared with ACC alone to evaluate the validity of ACC and HR used alone or combined. The purpose of this study was to estimate AEE in free-living conditions compared with doubly labeled water ...
Gupta Mamta M Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA. - - 2012
STAT3 regulates cell growth by up-regulating downstream targets, such as Myc. The frequency of phosphorylated STAT3 (pSTAT3) and Myc expression and their prognostic relevance is unknown within diffuse large B-cell lymphoma (DLBCL) germinal center B-cell (GCB) and non-GCB subtypes. pSTAT3 and Myc were studied by immunohistochemistry (IHC) on tumors from ...
Felmy Andrew R - - 2012
Time-dependent reduction of PuO2(am) was studied over a range of pH values in the presence of aqueous Fe(II) and magnetite (Fe3O4) nanoparticles. At early time frames (up to 56 days) very little aqueous Pu was mobilized from PuO2(am), even though measured pH and redox potentials, coupled to equilibrium thermodynamic modeling ...
Ekshyyan Oleksandr - - 2012
OBJECTIVES/HYPOTHESIS: The early detection of persistent/recurrent disease of head and neck squamous cell carcinoma (HNSCC) after treatment can be challenging. The currently used radioisotope (18) F-fluorodeoxyglucose (FDG) is a nonspecific tracer for cancer cells as it detects all metabolically active cells including inflammation. (18) F-fluorodeoxythymidine (FLT) is a radioactive tracer ...
Klug Jennifer L - - 2012
Here we document the regional effects of Tropical Cyclone Irene on thermal structure and ecosystem metabolism in nine lakes and reservoirs in northeastern North America using a network of high-frequency, in situ, automated sensors. Thermal stability declined within hours in all systems following passage of Irene, and the magnitude of ...
Gloede Tristan D - - 2012
 Effective coordination among all members of hospital staff has been shown to be associated with better quality of care. The literature indicates that social capital, a form of organizational resource, may facilitate the task of coordination. However, to the best of our knowledge, no study has yet examined this link ...
Pastor William A - - 2012
5-Hydroxymethylcytosine (5hmC) is a newly discovered DNA base present at detectable levels in most mammalian cell types and tissues. It is generated by Tet-enzyme-mediated oxidation of 5-methylcytosine (5mC). 5hmC is important both because of its potential role in regulating gene expression and because it may be an intermediate in DNA ...
Maher Mohammad Ahmed - - 2012
Objective. To assess efficacy and tolerability of vaginal compared to intramuscular progesterone in reducing the rate of recurrent preterm birth before 34 weeks gestation. Design. Prospective randomized study. Setting. Obstetrics and Gynecology Department, Armed Forces Hospital Southern Region, Kingdom of Saudi Arabia. Sample. Five-hundred and eighteen patients with a prior ...
Do Ngoc Quang - - 2012
Guanine-rich sequence motifs, which contain tracts of three consecutive guanines connected by single non-guanine nucleotides, are abundant in the human genome and can form a robust G-quadruplex structure with high stability. Herein, by using NMR spectroscopy, we investigate the equilibrium between monomeric and 5'-5' stacked dimeric propeller-type G-quadruplexes that are ...
Monajemi Hadieh - - 2012
Finding a proper transition structure for the peptide bond formation process can lead one to a better understanding of the role of ribosome in catalyzing this reaction. Using computer simulations, we performed the potential energy surface scan on the ester bond dissociation of P-site aminoacyl-tRNA and the peptide bond formation ...
Yoo Jejoong - - 2012
The concept of "ion atmosphere" is prevalent in both theoretical and experimental studies of nucleic acid systems, yet the spatial arrangement and the composition of ions in this at- mosphere remain elusive, in particular when several ionic species (e.g., Na+, K+, and Mg2+) compete to neutralize the charge of a ...
Cheng Edaire E Departments of Pediatrics, Children’s Medical Center, - - 2012
Eosinophilic esophagitis (EoE) is a recently recognized, immune-mediated disease characterized clinically by symptoms of esophageal dysfunction and histologically by eosinophil-predominant inflammation. The chronic esophageal eosinophilia of EoE is associated with tissue remodeling that includes epithelial hyperplasia, subepithelial fibrosis, and hypertrophy of esophageal smooth muscle. This remodeling causes the esophageal rings ...
Böttcher Artur - - 2012
Molecular oxygen etching of HOPG surfaces prepatterned by Ga(+) focused-ion-beam irradiation (FIB) has been used to generate large-area arrays of nanometer-sized graphite blocks. AFM and SEM imaging show that structures with lateral sizes down to ∼100 nm and heights of between 30 and 55 nm can be routinely fabricated. The trenches separating ...
Dolcos Sanda S Psychology Department, 2057 Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 405 North Mathews Avenue, Urbana, IL 61801, USA. - - 2012
Effective social interactions require the ability to evaluate other people's actions and intentions, sometimes only on the basis of such subtle factors as body language, and these evaluative judgments may lead to powerful impressions. However, little is known about the impact of affective body language on evaluative responses in social ...
Ruff Christian M - - 2012
The complexation of Cm(iii) and Eu(iii) with 2,6-bis(5,6-di(sulfophenyl)-1,2,4-triazin-3-yl)pyridine (aq-BTP) is studied in water at pH 3.0 applying time-resolved laser fluorescence spectroscopy. With increasing ligand concentration [M(H(2)O)(9-3n)(aq-BTP)(n)] (M = Cm(iii)/Eu(iii), n = 1, 2, 3) complex species are spectroscopically identified. The conditional stability constants of the M(iii) 1 : 3 complex species with ...
Sopha Pattarawut - - 2012
Misfolded proteins in the endoplasmic reticulum (ER) are dislocated out of the ER to the cytosol, polyubiquitinated, and degraded by the ubiquitin-proteasome system in a process collectively termed ER-associated degradation (ERAD). Recent studies have established that a mammalian ER-localized transmembrane J-protein, DNAJB12, cooperate with Hsc70, a cytosolic Hsp70 family member, ...
Zhang Yanfeng - - 2012
An efficient three-component reaction toward the facile synthesis of structurally diverse 1-carboxamido-isoindoles has been developed. The resultant isoindoles can be used in Diels-Alder reactions.
Patai Eva Zita EZ University of Oxford, - - 2012
In everyday situations, we often rely on our memories to find what we are looking for in our cluttered environment. Recently, we developed a new experimental paradigm to investigate how long-term memory (LTM) can guide attention and showed how the pre-exposure to a complex scene in which a target location ...
Buettner Katherine M - - 2012
Ascorbic acid is among the biorelevant ligands that render Ti(IV) stable in aqueous solution. A series of pH-dependent titanium(IV) coordination complexes of l-ascorbic acid is described. Directed by spectropotentiometric methods, important aspects of the aqueous interactions in this system are investigated, including ligand binding mode, pH-dependent metal-ligand stoichiometry, and the ...
Soh Nerissa - - 2012
OBJECTIVES: This study aimed to qualitatively explore medical students' reasons for suspending, or thinking of suspending, their studies and the types of support services they request. METHOD: Data were collected through an anonymous online survey. Medical students' responses to open-ended questions were analyzed thematically. RESULTS: Responses were received from 475 ...
Deksne Gunita - - 2012
Abstract We sampled 339 fecal samples, 296 intestines, and 82 lungs from 371 lynx hunted during the 2010-2011 season in Finland. The fecal samples were analyzed for endoparasites by a quantitative flotation method and helminths from intestines were studied morphologically, while lungs were investigated for pulmonary parasites. From fecal samples, ...
Seyal Masud M Department of Neurology, University of California Davis, Sacramento, California, USA. - - 2013
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related mortality. Seizure-related respiratory dysfunction (RD), the duration of postictal generalized electroencephalography (EEG) suppression (PGES), and duration of postictal immobility (PI) may be important in the pathophysiology of SUDEP. Periictal interventions may reduce the risk of SUDEP. We assessed ...
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