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Lima Joelma Sousa - - 2012
Oral leukoplakias (OL) are potentially malignant lesions that are typically white in color. Smoking is considered a risk factor for developing OL, and dysplastic lesions are more prone to malignant transformation. The aim of this study was to describe the clinical features observed in dysplastic and non-dysplastic OL in both ...
Wen Liping - - 2012
A highly efficient and perfectly reversible ionic gate that can be activated by pH or UV light is demonstrated. Switching between the OFF state and the ON state is mainly dependent on the surface charge transition brought about by the malachite green derivative attached to the interior surface of an ...
Liu Shao Qiong - - 2012
A novel class of antimicrobial cationic polycarbonate/PEG hydrogels are designed and synthesized by Michael addition chemistry. These hydrogels demonstrate strong broad-spectrum antimicrobial activities against various clinically isolated multidrug-resistant microbes. Moreover, they exhibit nonfouling properties and prevent the substrate from microbial adhesion. These antimicrobial and antifouling gels are promising materials as ...
Kotková Zuzana - - 2012
Middle-molecular-weight MRI contrast agents based on conjugates of a phosphinic acid DOTA analogue, 1,4,7,10-tetraazacyclododecane-4,7,10-triacetic-1-{methyl[(4-aminophenyl)methyl]phosphinic acid} (DO3AP(ABn)), with amino-substituted cyclodextrins were prepared and studied by a variety of physico-chemical methods. The conjugates were formed by reaction of the corresponding isothiocyanate with per-6-amino-α/β-cyclodextrin and were complexed with the Ln(iii) ion to get ...
Granek Leeat - - 2012
Abstract Background: While caring for critically ill and terminal patients can elicit grief symptoms in health care professionals, few studies have examined oncologists' grief over patient loss using a qualitative approach to inquiry. Objectives: To explore what makes patient loss difficult for oncologists and to explore the context in which ...
Nammontri O - - 2012
Sense of coherence (SOC) has been related to oral health behaviors and oral-health-related quality of life (OHRQoL) in observational studies. This cluster-randomized trial aimed to test the effect of an intervention to enhance SOC on OHRQoL in children. Twelve primary schools were randomly allocated to intervention and control groups. The ...
Lee Wonsuk - - 2012
DNA melting analysis holds great promise for simple and fast DNA sequence discrimination. However, conventional fluorescence based methods suffer from a small differential signal and demanding melting curve analysis, both of which make it difficult to distinguish the target DNA from the mismatched one. Herein, we propose and demonstrate a ...
Henk H J - - 2012
Abstract Objective: Few studies have compared the effectiveness of filgrastim (FIL), pegfilgrastim (PEG), and sargramostim (SAR) to reduce the risk of febrile neutropenia (FN) associated with myelosuppressive chemotherapy (M-CT). Two large commercial database analyses were separately conducted to examine the incidence of neutropenia-related and all-cause hospitalizations associated with FIL, PEG, ...
Corso Annalisa Rossi Del - - 2012
Since the 1990s researchers have considered as the dominant view on family obligation a set of responsibilities, duties, and obligation of care and assistance,that adult children should assume when parents are old or infirm. This concept is limited, because it assumes that family obligation is salient only in one period ...
Zhang Zhi-Jiang - - 2012
BACKGROUND: Oxidative stress may play an aetiological role in the development and progression of cardiovascular disease (CVD). However, evidence on its biochemical markers has been controversial. This article aimed to assess the role of F(2)-isoprostanes as a biomarker for CVD, including coronary artery disease, stroke and peripheral artery disease. METHODS: ...
Demirturk Orhan Saim - - 2012
PURPOSE: We aimed to describe the long-term outcome of endovascular treatment of iliofemoral deep vein thrombosis in the postpartum period. MATERIALS AND METHODS: Between 2002 and 2010, 18 consecutive female patients with acute or subacute iliofemoral deep vein thrombosis in the postpartum period who had endovascular treatment were retrospectively evaluated. ...
Shigematsu Kazuo - - 2012
BACKGROUND: To predict the outcome of stroke at an acute stage is important but still difficult. Vomiting is one of the commonest symptoms in stroke patients. The aim of this study is threefold: first, to examine the percentage of vomiting in each of the three major categories of strokes; second, ...
Traa Marjan Johanna - - 2012
Introduction.  Even though the body of literature on sexual functioning is growing, information on the preoperative sexual functioning and the quality of sexual life after colorectal cancer is lacking. Research focusing on female patients and on partners is also rather scarce. Aim.  This cross-sectional study aimed to describe the preoperative ...
Picchi Jacopo - - 2012
Human stromal stem cell populations reside in different tissues and anatomical sites, however a critical question related to their efficient use in regenerative medicine is whether they exhibit equivalent biological properties. Here, we compared cellular and molecular characteristics of stromal stem cells derived from the bone marrow, at different body ...
Zhang Taylor - - 2012
We describe here the identification of a stop codon TAA (Stop) → GAA (Glu) = Stop221E mutation on the light chain of a recombinant IgG1 antibody expressed in a Chinese hamster ovary (CHO) cell line. The extended light chain variants, which were caused by translation beyond the mutated stop codon ...
Celebrano Michele - - 2012
We demonstrate the ability to trap, levitate and orient single anisometric nanoscale objects with high angular precision in a fluid. An electrostatic fluidic trap confines a spherical object at a spatial location defined by the minimum of the electrostatic system free energy. For an anisometric object and a potential well ...
Islam Mohammad Aminul - - 2012
The purpose of the study was to screen for reduced susceptibility against imipenem and the presence of the New-Delhi Metallo-β-lactamase-1 (NDM-1) gene in a collection of Enterobacteriaceae (E. coli, Shigella spp. and Klebsiella pneumoniae) from different surveillance studies between 2003 and 2010 at the International Centre for Diarrhoeal Disease Research, ...
Shinde K N - - 2012
A series of efficient Li(3) Al(2) (PO(4) )(3) :Eu(2+) novel phosphors were synthesized by the facile combustion method. The effects of dopant on the luminescence behavior of Li(3) Al(2) (PO(4) )(3) phosphor were also investigated. The phosphors were characterized by X-ray diffraction, field emission scanning electron microscope and photoluminescence techniques. ...
Carter S - - 2012
BACKGROUND: The plasma renin activity (PRA) assay measures the ability of renin to generate angiotensin I (AngI) from angiotensinogen. It is used to monitor mineralocorticoid therapy and to screen hypertensive individuals for primary aldosteronism (PA). METHODS: Samples were incubated in the presence of protease inhibitors for 6.5 and 24 h. ...
Icli Burcak - - 2012
Multicomponent reactions between 1,4-benzenediboronic acid, catechol, and different pyridyl ligands are reported. The condensation of 1,4-benzenediboronic acid with catechol gives 1,4-bis(benzodioxaborole)benzene. Upon crystallization, the ester aggregates with the N-donor ligands through dative BN bonds. Depending on the nature of the pyridyl ligand, molecularly defined macrocycles or polymeric structures are obtained. ...
Pati Sarah G - - 2012
Dioxygenation of aromatic rings is frequently the initial step of biodegradation of organic subsurface pollutants. This process can be tracked by compound-specific isotope analysis to assess the extent of contaminant transformation, but the corresponding isotope effects, especially for dioxygenation of N-substituted, aromatic contaminants, are not well understood. We investigated the ...
Cappelleri Joseph C - - 2012
What's known on the subject? and What does the study add? Studies on erectile dysfunction (ED) therapies rely heavily on patient-reported outcomes (PROs) to measure efficacy on treatment response. A challenge when using PROs is interpretation of the clinical meaning of changes in scores. A responder analysis provides a threshold ...
Barger Anne M - - 2012
BACKGROUND: Erythrophagia has been identified in multiple types of tumors in human medicine, but information in veterinary medicine is limited. In dogs and cats, erythrophagia has been reported to occur in mast cell and plasma cell tumors, lymphoma, megakaryocytic leukemia, and hemophagocytic histiocytic sarcoma. On the basis of clinical experience, ...
Yanagisawa Rie - - 2012
Acute ozone (O(3)) exposure causes oxidative stress leading inflammation in the lung. However, its precise mechanisms are not fully elucidated. Here we examined the role of peroxiredoxinI (PrxI) in O(3)-induced pulmonary inflammation using PrxI null (PrxI(-/-)) and wild type (WT) mice. PrxI is known as an antioxidant and also emerged ...
Liang Ran - - 2012
Giant unilamellar vesicles (GUVs of diameter 5-25 μm) of soy phosphatidylcholine (PC), resistent to intense light exposure (400-440 nm, ~15 mW∙mm-2), underwent budding when containing chlorophyll a (Chla) in the lipid bilayer ([PC]:[Chla]=1500:1). Based on image heterogeneity analysis using inverted microscopy, a dimensionless entropy parameter for the budding process was ...
Efken Christina - - 2012
This study investigated the effect of heart failure (HF) on respiratory patterns in patients with obstructive sleep apnoea (OSA).Thirty-nine patients with established OSA (apnoea-hypopnoea index [AHI] >10·h(-1)) and with HF (NYHA II+III, LVEF ≤40%; n=26, age 67±9 years) or without HF (LVEF ≥50%, NT-proBNP <400 ;pg·mL(-1); n=13, age 73±6 years) ...
Pareek Manish - - 2012
BACKGROUND: Emerging evidence suggests that Mycobacterium tuberculosis (Mtb) lineage and host ethnicity can determine tuberculosis (TB) clinical disease patterns but their relative importance and interaction are unknown. METHODS: We evaluated prospectively collected TB surveillance and Mtb strain typing data in an ethnically heterogeneous UK population. Lineage assignment was denoted using ...
Jacques Suzanne M - - 2012
A case of hemangioma of the umbilical cord with an associated amnionic epithelial inclusion cyst (4.5 cm in maximum dimension), diagnosed by pathological examination at 26 weeks of gestation following in utero fetal demise, is reported. These are both uncommon lesions of the umbilical cord, and to our knowledge, have not ...
Antonova Elena S - - 2012
Competence for genetic transformation in Vibrio cholerae is triggered by chitin-induced transcription factor TfoX and quorum sensing (QS) regulator HapR. Transformation requires expression of ComEA, described as a DNA receptor in other competent bacteria. A screen for mutants that poorly expressed a ΔcomEA-luciferase fusion identified cytR, encoding the nucleoside scavenging ...
Petriz Bernardo A - - 2012
Exercise is recognized to prevent and attenuate several metabolic and cardiovascular disorders. Obesity is commonly related to cardiovascular diseases, frequently resulting in heart failure and death. To elucidate the effects of acute exercise in heart tissue from obese animals, twelve-week-old C57BL6/J obese (ob/ob) and non-obese (ob/OB) mice were submitted to ...
Lambert Isabelle - - 2012
Purpose:  Loss of consciousness (LOC) in epileptic seizures has a strongly negative impact on quality of life. Recently, we showed that LOC occurring during temporal lobe seizures was correlated with a nonlinear increase of neural synchrony in associative-and particularly parietal-cortices. Whether these mechanisms might be observed in other types of ...
Xue Lin - - 2012
Fluorescent detecting and tracking of zinc ions in living cells has become more and more important because the physiological and pathological functions of zinc are highly associated with the timing and discrete distribution of subcellular zinc ion. For the detection of subcellular zinc concentrations with high spatial and temporal reliability, ...
Zheng Zhan-Jiang - - 2012
An interesting example of a divergent catalysis with a copper(I) and amine-functional macromolecular polysiloxanes system was successfully presented in click chemistry. In this manuscript, we demonstrate the remarkable ability of the secondary amine-functional polysiloxane to induce oxidative coupling in the copper-mediated Huisgen reactions of azides and alkynes, thereby achieving good ...
Hallowell Gayle D - - 2012
ABSTRACT: BACKGROUND: Echocardiography is a non-invasive method for assessment of the ovine and caprine heart. Complete reference ranges for cardiac dimensions and time indices for both species are not currently available and reliability of these measurements has not been evaluated. The objectives for this study are to report reliability, normal ...
Jones Tim - - 2012
Two experiments used immediate probed recall of words to investigate serial-position effects. Item memory was tested through probing with a semantic category. Relation memory was tested through probing with the word's spatial location of presentation. Input order and output order were deconfounded by presenting and probing items in different orders. ...
Liao Hua-Yang - - 2012
In the past decade, buckminsterfullerene (C60)-based ion beams have been utilized in surface analysis instruments to expand their application to profiling organic materials. Although it had excellent performance for many organic and biological materials, its drawbacks, including carbon deposition, carbon penetration, continuous decay of the sputtering rate, and a rough ...
Ding Kewang - - 2012
WS(2) nanotubes were irradiated with a focused electron beam in an electron microscope. The results show that the nanotubes are destroyed from the outer layer to the inside. The displaced atoms can leave the irradiated area by sputtering events or by diffusive migration along the shells and the inner hollow. ...
Larrabide I - - 2012
BACKGROUND AND PURPOSE:Effects of blood flow modification by flow diverters are observed to lead often to aneurysm thrombosis and reverse remodeling. For this process, to further understand the potential roles of intra-aneurysmal blood pressure changes and aneurysm morphologies, 23 patients were studied by numeric simulation.MATERIALS AND METHODS:3D imaging of aneurysms ...
Costello Christopher - - 2012
Recent reports suggest that many well-assessed fisheries in developed countries are moving toward sustainability. We examined whether the same conclusion holds for fisheries lacking formal assessment, which comprise >80% of global catch. We developed a method using species' life history, catch, and fishery development data to estimate the status of ...
Rives Arnaud - - 2012
The first examples of a novel family of sp-carbon-rich n-π-conjugated oligomers/polymers, namely carbo-mers of polyacetylene, also referred to as "1,4-PTA" isomers of the classical polytriacetylenes (1,2-PTAs), are described in the perphenylated series. The two first representatives proved to be stable in solution, and exhibit a zig-zag arrangement in the crystal ...
Koerbin Gus - - 2012
BACKGROUND:There is little information available on cardiac troponin concentrations in healthy young children.METHODS:Using a precommercial high-sensitivity assay from Abbott Diagnostics, we measured cardiac troponin I (cTnI) in longitudinal blood samples collected at ages 8, 10, and 12 years from a cohort of healthy, community-dwelling children. The 99th percentile values were ...
Jorgensen Kameron Renee - - 2012
To focus on the identification of potential alternative amine carbon capture compounds, CO(2) with methyl, silyl, and trifluoromethyl monosubstituted and disubstituted amine compounds were studied. Interaction energies of these CO(2)•amine complexes were determined. via two methods: a) an ab initio composite method, the correlation consistent Composite Approach (ccCA), to determine ...
Treur M - - 2012
Abstract Background: Paliperidone Extended Release OROS (ER) is a new atypical antipsychotic for the treatment of schizophrenia. The objective is, based on a previously published model, to analyze the clinical and economic effects of Paliperidone ER in a Spanish setting compared to olanzapine oral and aripiprazole. Methods: An existing discrete ...
Hizukuri Yohei - - 2012
The Escherichia coli σ(E) extracytoplasmic stress response monitors and responds to folding stress in the cell envelope. A protease cascade directed at RseA, a membrane-spanning anti- that inhibits σ(E) activity, controls this critical signal-transduction system. Stress cues activate DegS to cleave RseA; a second cleavage by RseP releases RseA from ...
Balan L - - 2012
A facile method for the preparation of gold nanoparticles (AuNPs) with various morphologies, including triangles, cubes and nanospheres into a urethane methacrylate polymer matrix, has been developed. The hybrid nanocomposites have been obtained by photoreduction of a gold precursor in the presence of a 30 wt% urethane methacrylate containing quaternary ammonium ...
Bubnova Olga - - 2012
While organic field-effect transistors allow investigation of the interfacial charge transport at the semiconductor-dielectric interface, an electrochemical transistor truly modifies the oxidation level and conductivity through the bulk of an organic semiconductor. Here, the thermoelectric properties of the bulk of the conducting polymer poly(3,4-ethylenedioxythiophene)-poly(styrene sulfonate) are controlled electrically by varying ...
Park Hui Gyu - - 2012
This study was performed to investigate the effect of high hydrostatic pressure (HHP) on the conversion of linoleic acid, conjugated linoleic acid (CLA) and α-linolenic acid (α-LNA) as substrates by Bifidobacterium breve LMC520 and to optimize the HHP condition. Cell mixture were tested under HHP in a variety of conditions ...
Gao Detian - - 2012
A versatile new synthesis of indoles was achieved by the conjugate addition of N-formyl-2-haloanilines to acetylenic sulfones, ketones, and esters followed by a copper-catalyzed intramolecular C-arylation. The conjugate addition step was conducted under exceptionally mild conditions at room temperature in basic, aqueous DMF. Surprisingly, the C-arylation was performed most effectively ...
Ona Mel A - - 2012
Several studies have reported influenza A (H1N1) virus as a cause of fulminant myocarditis. We report the first fatal case of fulminant myocarditis presenting as an acute ST-segment elevation myocardial infarction and ventricular tachyarrhythmia associated with influenza A (H1N1) in a previously healthy pregnant woman. A 38-year-old Asian woman, gravida ...
de Groot Eric P - - 2012
Background. Hyperventilation and other clinical manifestations of dysfunctional breathing (DB) have been reported in childhood, the prevalence is unknown. In adults dysfunctional breathing may be a relevant co-morbidity in asthma.Objective. To determine the prevalence of dysfunctional breathing in children with asthma and its impact on asthma control.Methods. Cross-sectional survey in ...
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