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Dang-Nguyen Thanh Quang TQ Department of Animal Breeding and Reproduction, NARO Institute of Livestock and Grassland Science, Ibaraki 305-0901, Japan. - - 2013
Telomere is a nucleoprotein structure at the ends of chromosomes that helps to protect the ends of chromosomes from being fused with other chromosomes. Knockout of histone methyltransferases Suv39h1 and Suv39h2 increases the telomere length in murine cells, whereas downregulation of SUV39H1 and SUV39H2 genes decreases the telomere length in ...
Venditti Rossella R Telethon Institute of Genetics and Medicine, Naples, - - 2012
Newly synthesized proteins exit the endoplasmic reticulum (ER) via coat protein complex II (COPII) vesicles. Procollagen (PC), however, forms prefibrils that are too large to fit into typical COPII vesicles; PC thus needs large transport carriers, which we term megacarriers. TANGO1 assists PC packing, but its role in promoting the ...
Taylor Jeanette J Department of Psychology, Florida State University, Tallahassee, FL 32306-4301, USA. - - 2013
Childhood behavioral disorders including conduct disorder (CD), oppositional defiant disorder (ODD), and attention-deficit/hyperactivity disorder (ADHD) often co-occur. Prior twin research shows that common sets of genetic and environmental factors are associated with these various disorders and they form a latent factor called Externalizing. The developmental propensity model posits that CD ...
Chiu Yvonne E YE Division of Pediatric Dermatology, Department of Dermatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA. - - 2013
Piebaldism is a rare genodermatosis caused by KIT mutations. We report the case of a 5-year-old boy who had the white forelock and leukoderma of piebaldism, but the presence of many café-au-lait macules and axillary and inguinal freckling complicated the diagnosis. Patients with similar cutaneous findings have been previously reported, ...
Achinger Steven G SG Department of Nephrology, Watson Clinic, LLP-Lakeland, FL, - - 2013
Daily hemodialysis has been associated with surrogate markers of improved survival among hemodialysis patients. A potential disadvantage of daily hemodialysis is that frequent vascular access cannulations may affect long-term vascular access patency. The study design was a 4-year, nonrandomized, contemporary control, prospective study of 77 subjects in either 3-h daily ...
Clover Kerrie - - 2012
OBJECTIVE: ]Although effective treatments for pain and distress are available, many patients do not access them. Improved understanding of patients' desire for help may improve uptake of services. METHODS: Data were collected as part of the QUICATOUCH screening program at an Australian regional hospital. Patients over threshold for pain were ...
A Maris - - 2012
Aim:  Common problems after rectal resection are loose stools, fecal incontinence, increased frequency and evacuation difficulties, for which there are various therapeutic options. A systematic review was conducted to assess the outcome of treatment options aimed to improve anorectal function after rectal surgery. Method:  Publications including a therapeutic approach to ...
Battaglini Nicolas - - 2012
We report on the elaboration of networks of SAM domains. More precisely, we show the feasibility in making arrays of functionalized alkylthiol nanodomains bordered with an alkylthiol matrix. The several step process relies on the replication of a self-organized cobalt array grown on Au(111). SAM process takes place in solution. ...
Kamishiraki Etsuko - - 2012
CONTEXT: Autopsy is a useful tool for understanding the cause and manner of unexpected patient death. However, the attitudes of the general public and physicians in Japan about clinical autopsy are limited. OBJECTIVE: To describe the beliefs of the general public about whether autopsy should be performed and ascertain if ...
Dimitrova Diana V - - 2012
Prosody, particularly accent, aids comprehension by drawing attention to important elements such as the information that answers a question. A study using brain ERPs registration investigated how the brain deals with the interpretation of prosodic prominence. Sentences were embedded in short dialogues and contained accented elements that were congruous or ...
Kawasaki Hideya - - 2012
Graphene-coated cobalt nanoparticles surface functionalized with benzylamine groups (CoC-NH2 nanomagnets) were shown to effectively enrich analytes for surface-assisted laser desorption/ionization mass spectrometry (affinity SALDI-MS) analysis. These CoC-NH2 nanomagnets are highly suited for use with affinity SALDI-MS because their mean diameter of 30 nm, high specific surface area of 15 m2•g-1, ...
Saison Julien - - 2012
BACKGROUND: Although likely pivotal, the role of regulatory T cells (Tregs) in HIV pathogenesis remains elusive. This can be partly explained by analytical issues regarding their phenotypic identification in clinical studies. Instead of intracellular FOXP3 staining, CD4+CD25+CD127- phenotype has been proposed as an alternative to identify Tregs in clinical samples. ...
Chaikittisilpa S - - 2012
ABSTRACT Objectives To develop a new instrument, the Menopause-specific Quality of Life Scale (MS-QoLS), for Thai women and to study the experience of menopausal aspects in peri- and postmenopausal Thai women. Materials and methods Item generation was developed from a focus group discussion and in-depth interview, and the content validity ...
Dalal Bakul I - - 2012
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is diagnosed by documenting partial or complete absence of glycosyl phosphatidyl inositol (GPI)-associated ligands in neutrophils, monocytes, and red blood cells (RBCs). The monocytes can be separated by their bright expression of either CD33 or CD64. This paper compares the utility of CD33- vs CD64-based ...
Chandra Rampalli Viswa - - 2012
Abstract Osteotome sinus floor elevation requires specific root analogue instruments for effective elevation of the sinus floor. Various osteotome kits for sinus floor elevation are available; however, they may be complex, bulky or expensive. This report describes the design of a custom-made osteotome and its use in two cases requiring ...
Delgado Carmen L - - 2012
In order to shed light on the hepatitis B virus fusion mechanism and to explore the fusogenic capabilities of preS regions, a recombinant duck hepatitis B virus preS protein (Dpres) containing six histidines at the carboxy-terminal end has been obtained. The DpreS domain, which has an open and mostly non-ordered ...
Roth Christian - - 2012
Abstract Interactive storytelling (IS) is a promising new entertainment technology synthesizing preauthored narrative with dynamic user interaction. Existing IS prototypes employ different modes to involve users in a story, ranging from individual avatar control to comprehensive control over the virtual environment. The current experiment tested whether different player modes (exerting ...
Siddiq Ishita - - 2012
Vascular endothelial growth factor (VEGF) plays a role in both angiogenesis and has been shown to be neuroprotective following central nervous system trauma. In the present study we evaluated the pro-angiogenic and neuroprotective effects of an engineered zinc-finger-protein transcription factor transactivator targeting the vascular endothelial growth factor A (VEGF-ZFP). We ...
Pasham Venkanna - - 2012
The oxidative stress responsive kinase 1 (OSR1) contributes to WNK-(with no K) dependent regulation of renal tubular salt transport, renal salt excretion and blood pressure. Little is known, however, about a role of OSR1 in the regulation of intestinal salt transport. The present study thus explored, whether OSR1 is expressed ...
Zhang Jie - - 2012
This paper presents a theoretical study of electrochemical affinity biosensors for the detection of DNA/protein that utilize nanoparticle labels for signal amplification. This study analyzes the effects of binding and mass transport of the analytes on biosensor performance by using numerical simulations. Four cases were considered: 1) nanoparticles used to increase ...
Pagac Martin - - 2012
All glycerophospholipids are made from phosphatidic acid, which, according to the traditional view, is generated at the cytosolic surface of the ER. In yeast, phosphatidic acid is synthesized de novo by two acyl-CoA dependent acylation reactions. The first is catalyzed by one of the two homologous glycerol-3-phosphate acyltransferases Gpt2p/Gat1p and ...
Yoon Ji Young - - 2012
PURPOSE: We aimed to compare clinical features and computed tomography (CT) findings of pulmonary tuberculosis (TB) in lower lobe basal segments and upper lobe apical or apicoposterior segments. MATERIALS AND METHODS: We retrospectively reviewed medical records and chest CT scans of 986 adults who were diagnosed with active pulmonary TB. ...
Cui Guanghui - - 2012
Controllable growth of newly born silver nanoparticles to fractal, cauliflower-like, microscale disks and continuous silver layers with high conductivity and reflectivity on plastic substrates has been developed via solid-liquid interfacial reduction and growing of ion-doped polymeric films. Such approaches involve polyimide (PI) films as substrates, its corresponding silver-ion-doped precursors as ...
Rideg Nóra Abrankó - - 2012
Molecular dynamics simulations of the adsorption layer of five different surfactant molecules, i.e., pentyl alcohol, octyl alcohol, dodecyl alcohol, sodium dodecyl sulfate and dodecyl trimethyl ammonium chloride are performed at the free surface of their aqueous solution at two surface densities, namely 1 and 4 μmol/m2 at 298 K. The ...
Phillips Ryan D - - 2012
A leading hypothesis for the immense diversity of the Orchidaceae is that skewed mating success and small, disjunct populations lead to strong genetic drift and switches between adaptive peaks. This mechanism is only possible under conditions of low gene flow that lead to high genetic differentiation among populations. We tested ...
Maheshwari Rajesh - - 2012
OBJECTIVE: Indian-Australians represent a distinct immigrant group both demographically and culturally. Yet, despite an expanding body of research on transcultural mental health in Australia, there is a paucity of studies regarding mental health of Indian-Australians. This paper explores the extent of psychological morbidity and related service use in a representative ...
Sahoo Swapan K - - 2012
Metazoans are likely to have their roots in the Cryogenian period, but there is a marked increase in the appearance of novel animal and algae fossils shortly after the termination of the late Cryogenian (Marinoan) glaciation about 635 million years ago. It has been suggested that an oxygenation event in ...
Demirel Gamze - - 2012
AIM: To determine reference values for cystatin C (CysC) and its correlation with creatinine (Cr), gestational age, birth weight and maternal Cr status in very low birth weight (VLBW) preterm infants. METHOD: The study included 113 VLBW premature infants (<1500 g) of ≤32 gestational week. Serum Cr and Cys C ...
Nassar Mariangela Salles Pereira - - 2012
The Lucia jig is a technique that promotes neuromuscular reprogramming of the masticatory system and allows the stabilization of the mandible without the interference of dental contacts, maintaining the mandible position in harmonic condition with the musculature in normal subjects or in patients with temporomandibular dysfunction (TMD). This study aimed ...
Störmer Viola S - - 2012
Declines in selective attention are one of the sources contributing to age-related impairments in a broad range of cognitive functions. Most previous research on mechanisms underlying older adults' selection deficits has studied the deployment of visual attention to static objects and features. Here we investigate neural correlates of age-related differences ...
Faggiano A - - 2012
Purpose:Percutaneous radiofrequency thermal ablation (RTA) was reported as an effective tool for the management of thyroid nodules (TNs). The aim of this study was to investigate the effects of RTA and to establish whether they were treatment-related by comparison with a matched, untreated control group.Patients and Methods:The study population included ...
Liu Feng - - 2012
Abstract  This case report describes a woman at 35 weeks gestation, who presented with an acute type A aortic dissection involving the total aortic arch and descending aorta. She underwent a successful ascending aorta replacement, total arch replacement, and stented elephant trunk implantation at the time of cesarean section with ...
Weaver Andrew J - - 2012
Abstract This exploratory study was designed to examine how players make moral choices in video games and what effects these choices have on emotional responses to the games. Participants (n=75) filled out a moral foundations questionnaire (MFQ) and then played through the first full act of the video game Fallout ...
Gosselin Nadia - - 2012
More than 75% of patients with mild traumatic brain injury (MTBI) report chronic pain whose potential detrimental effects on cognitive recovery need to be identified. The objective of this study was to investigate the relationship between pain, performance on a working memory task, grey matter density and mid-dorsolateral prefrontal cortex ...
- - 2012
The Department of Veterans Affairs (VA) is taking direct final action to amend its regulations concerning per diem payments to State homes for the provision of nursing home care to veterans. Specifically, this rule removes the requirement that a veteran must have resided in a State home for 30 consecutive ...
Machan Charles W - - 2012
Herein, we report the one-pot synthesis of Fe(II) bis-terpyridine complexes with two peripheral square planar Pt(II) bis-phosphinoalkylthioether moieties. These novel structures, which exhibit allosterically controllable electronic properties, are made by taking advantage of two orthogonal and high-yielding reactions. The prototypical complex can be structurally regulated through the reversible abstraction and ...
Golub Alla A - - 2012
Recent research has shed light on the cost-effective contribution that agriculture can make to global greenhouse gas abatement; however, the resulting impacts on agricultural production, producer livelihoods, and food security remain largely unexplored. This paper provides an integrated assessment of the linkages between land-based climate policies, development, and food security, ...
Tang Bor Luen - - 2012
Cytokinesis, the last major step of cell division, is a complex multistage process involving specific rearrangement of cellular cytoskeleton and a flurry of vesicular transport activities at the cell division plane. Vesicular traffic from the exocytic pathway and the endocytic/recycling pathway, operating again after being shut down since prophase, are ...
Dolcetti Alessia - - 2012
Purpose:Rare, recurrent chromosome 1q21.1 duplications have been associated with developmental delay, congenital anomalies, and macrocephaly in children. Data on adult clinical expression would help to inform genetic counseling.Methods:A systematic review of 22 studies reporting 107 individuals (59 children and 48 adults) with 1q21.1 duplications was conducted. We compiled the available ...
Horne Steven D - - 2012
The archetype driving the drug targeting approach to cancer therapy is the success of imatinib against chronic phase chronic myeloid leukemia (CML-CP). Molecular targeting success of this magnitude has yet to be repeated for most solid tumors. To answer why imatinib remains an exception of cancer research, we summarize key ...
Goel Sarika - - 2012
The synthesis protocols for encapsulation of metal clusters reported here expand the diversity in catalytic chemistries made possible by the ability of microporous solids to select reactants, transition states, and products based on their molecular size. We report a synthesis strategy for the encapsulation of noble metals and their oxides ...
Loridon Karine - - 2012
Extensive genomic resources are available in the model legume Medicago truncatula. Here, we present the discovery and design of the first array of single-nucleotide polymorphism (SNP) markers in M. truncatula through large-scale Sanger resequencing of genomic fragments spanning the genome, in a diverse panel of 16 M. truncatula accessions. Both anonymous fragments ...
Chowdhury Indranil - - 2012
In this study, a systematic approach has been followed to investigate the fate and transport of single walled carbon nanotubes (SWCNTs) from synthesis to environmentally relevant conditions. Three widely used SWCNT synthesis methods have been investigated in this study including high pressure carbon monoxide (HiPco), SWeNT CoMoCat, and electric arc ...
Noonan Kevin Joseph Taaffe - - 2012
A tetra(dialkylamino)phosphonium cation was evaluated as a functional group for alkaline anion exchange membranes (AAEMs). The base stability of [P(N(Me)Cy)4]+ was directly compared to that of [BnNMe3]+ in 1 M NaOD/CD3OD. The high base stability of [P(N(Me)Cy)4]+ relative to [BnNMe3]+ inspired the preparation of AAEM materials composed of phosphonium units ...
Schmidt Shelly J - - 2012
Our response to "Comment on the melting and decomposition of sugars" by Roos et al. (1) is organized into three sections: 1) Explanation of terminology used and possible misunderstanding of our conclusion, 2) Additional points of clarification and discussion, and 3) An analytical solution to determining the cause of the ...
Rörby Emma - - 2012
Hematopoietic stem cells (HSCs) constitute a rare population of tissue-specific cells that can self-renew and differentiate into all lineages of the blood cell system. These properties are critical for tissue regeneration and clinical applications of HSCs. Cord blood is an easily accessible source of HSCs. However, the number of HSCs ...
Jaquiéry J - - 2012
A major goal in evolutionary biology is to uncover the genetic basis of adaptation. Divergent selection exerted on ecological traits may result in adaptive population differentiation and reproductive isolation and affect differentially the level of genetic divergence along the genome. Genome-wide scan of large sets of individuals from multiple populations ...
Jiang Heng - - 2012
Direct CH functionalization of various enamides and enecarbamates was realized through visible-light photoredox catalyzed reactions. Under the optimized conditions using [Ir(ppy)(2) (dtbbpy)PF(6) ] as photocatalyst in combination with Na(2) HPO(4) , enamides such as N-vinylpyrrolidinone could be easily functionalized by irradiation of the reaction mixture overnight in acetonitrile with visible ...
Roos Yrjö H - - 2012
Melting of sugars has been studied by numerous authors, including Roos (1) and many others, as summarized in Lee et al. (2). Lee et al. (2-5) published a series of papers on melting of sugars, studied almost exclusively using variations of differential scanning calorimetry (DSC). These publications have opened up ...
Doeleman Sheperd S - - 2012
Approximately 10% of active galactic nuclei exhibit relativistic jets, which are powered by accretion of matter onto super massive black holes. While the measured width profiles of such jets on large scales agree with theories of magnetic collimation, predicted structure on accretion disk scales at the jet launch point has ...
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