Search Results
Results 351 - 400 of 2252
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Rivera Caroline - - 2012
To describe delays in diagnosis and treatment of lung cancer in patients treated by radiotherapy from the first abnormal imaging to the first day of treatment. Our retrospective single-center study included all patients treated for primary lung cancer in our center receiving radiotherapy alone or in association to chemotherapy or ...
Menting Roel - - 2012
Porphyrins, phthalocyanines and subphthalocyanines are three attractive classes of chromophores with intriguing properties making them suitable for the design of artificial photosynthetic systems. The assembly of these components by a supramolecular approach is of particular interest as it provides a facile means to build multi-chromophoric arrays with various architectures and ...
Megged Orli - - 2012
Fusobacterium necrophorum causes various clinical syndromes, ranging from otitis media to life-threatening Lemierre's syndrome. The purpose of this study was to review our experience with pediatric Fusobacterium infections. The medical records of all children aged 0 to 18 years who were diagnosed between 1999 and 2011 with Fusobacterium infection were reviewed. ...
Correa Cleiton Silva CS Physical Education School, Federal University of Rio Grande do Sul, Street Felizardo, 750, Jardim Botânico, CEP: 90690-200, Porto Alegre, Rio Grande do Sul RS, Brazil, - - 2013
Strength training seems to be an interesting approach to counteract decreases that affect knee extensor strength, muscle mass and muscle quality (force per unit of muscle mass) associated with ageing. However, there is no consensus regarding the changes in muscle mass and their contribution to strength during periods of training ...
Spence Graeme T - - 2012
Investigations to exploit the anion binding induced conformational changes displayed by a new class of acyclic receptor for anion recognition, fluorescence sensing and pseudorotaxane disassembly are described. A series of imidazolium-appended bis-amide-pyridine, pyridine N-oxide and pyridinium containing receptors are synthesised and their anion binding properties elucidated using (1)H NMR spectroscopy. ...
Zou Jun - - 2012
Combination therapies are urgently needed for optimal clinical benefit, but an efficient strategy for rational discovery of drug combinations, especially combinations of experimental drugs, is still lacking. Consequently, we proposed here a network-based computational method to identify novel synergistic drug combinations. A large-scale drug combination network (DCN), which provides an ...
van der Meulen Marian - - 2012
Motor imagery (MI) is often used in combination with neuroimaging techniques to study the cognitive control of gait. However, imagery ability (IA) varies widely across individuals, potentially influencing the pattern of cerebral recruitment during MI. The aim of the current study was to investigate this effect of IA on the ...
Peroni Diego G - - 2012
Abstract Colostrum contains cellular components that convey immunological protection to offspring. In the present study the main subsets of lymphocytes present in colostrum and in peripheral blood of healthy screened mothers were compared through the evaluation of more than 15 different flow cytometry markers. Colostrum and peripheral blood samples were ...
Wei Yong-Biao - - 2012
Vanadium complexes are potent hypoglycemic agents and of great potential for therapeutical treatment of diabetes. In the present work, a novel vanadium compound, bis ((5-hydroxy-4-oxo-4H-pyran-2-yl)methyl benzoatato) oxovanadium (IV) (BBOV) has been synthesized. Treatment of STZ-induced diabetic rats with BBOV restored the blood glucose to normal level and ameliorated glucose tolerance. ...
Maachou Hamida - - 2012
Chitosan/hydroxyapatite composite microparticles were prepared by a solid-in-water-in-oil emulsification cross-linking method. The characteristics and activity in presence of simulated body fluid for 14 and 21 days were investigated. The size distribution, surface morphology, and microstructure of these biomaterials were evaluated. The scanning electron microscopy revealed an aggregate of microparticles with a ...
Lubrano Vincent - - 2012
The production of object and action words can be dissociated in aphasics, yet their anatomical correlates have been difficult to distinguish in functional imaging studies. To investigate the extent to which the cortical neural networks underlying object- and action-naming processing overlap, we performed electrostimulation mapping (ESM), which is a neurosurgical ...
van Leersum N J - - 2012
Comorbidity has large impact on colorectal cancer (CRC) treatment and outcomes and may increase as the population ages. We aimed to evaluate the prevalence and time trends of comorbid diseases in CRC patients from 1995-2010. The Eindhoven Cancer Registry registers comorbidity in all patients with primary CRC in the South ...
Moolla Zaheer - - 2012
BACKGROUND: The etiology of acute pancreatitis can be difficult to determine early in the course of the disease. The aim of the present study was to determine the relationship between biochemical parameters and the cause of acute pancreatitis. METHODS: A prospectively collected database of patients admitted with acute pancreatitis between ...
Rastogi Shishir - - 2012
A prospective study was undertaken to evaluate the diagnostic and prognostic significance of serum levels of vascular endothelial growth factor (VEGF) in patients with primary localised osteosarcoma. Serum VEGF levels were measured by an enzyme-linked immunosorbent assay (ELISA) in blood samples collected prechemotherapy, postchemotherapy, and postsurgery in 40 patients with ...
Sorkhabi Rana - - 2012
Corneal ulcer is a devastating corneal disease which is potentially sight-threatening and conventionally is treated by topical antibiotics and in some cases with more invasive procedures such as keratoplasty. The aim of this study is to evaluate the efficacy of corneal collagen cross-linking in resistant corneal ulcers. Ten patients with ...
Kim Hye Jin - - 2012
PURPOSE: Recently, a single-stapled technique (SST) was performed instead of the conventional double-stapled technique (DST) in laparoscopic low anterior resection for anastomosis, by placement of intracorporeal purse-string sutures on the distal rectum with transanal specimen extraction. This study aimed to compare the short-term outcomes between the two anastomotic techniques. METHODS: ...
Shimizu Seiichi - - 2012
A 76-year-old male was referred for the treatment of liver tumors detected by abdominal computed tomography (CT). Dynamic CT revealed a low-density tumor with an irregularly enhanced rim in the left lateral sector, and a highly enhanced, well-circumscribed tumor in the caudate lobe, accompanied by dilation of the intrahepatic biliary ...
Bizub Anne L - - 2012
Recovery from mental illness is a complex journey that is greatly facilitated when client and professional helper collaborate in the decision making process. It is further aided when the latter has an empathetic awareness of the client's experience, especially with regard to the impact of pharmacological treatment. The following article ...
Kinsella J A - - 2012
An important proportion of transient ischemic attack or ischemic stroke is attributable to moderate or severe (50-99%) atherosclerotic carotid stenosis or occlusion. Platelet biomarkers have the potential to improve our understanding of the pathogenesis of vascular events in this patient population. A detailed systematic review was performed to collate all ...
Lee Ho-Cheng - - 2012
This study develops a novel and high performance colorimetric probe for dopamine (DA) detection. Aqueous-phase gold nanoparticles (AuNPs) extracted with 4-(dimethylamino)pyridine (DMAP) from toluene solvent are used as the reaction probes. The original AuNPs of diameter around 13 nm separate into 2-5 nm sizes when dopamine (DA) is added, resulting ...
Li Jing - - 2012
An electrochemically induced sol-gel process has been used to efficiently immobilize Ru(bpy)(3)(2+) in a 3D porous silica film matrix deposited on a glassy carbon electrode (GCE), forming a solid state electro-chemiluminescence (ECL) sensor. In this approach, electrolysis of the GCE at cathodic voltages from a solution of ammonium fluorosilicate containing ...
Steensma David P - - 2012
Just as a pawnshop owner who is unable to distinguish a genuine Rolex™ watch from a cheap knockoff courts financial ruin, the physician who fails to discriminate between authentic myelodysplastic syndromes (MDS) and conditions resembling MDS risks misinforming or harming patients. This review summarizes minimal criteria for diagnosing MDS and ...
Ke Xi - - 2012
Scatter me: A fast and cost-effective approach for the fabrication of surface-enhanced Raman scattering (SERS) arrays is developed. The method applied combines microcontact printing, electrodeposition, and galvanic replacement without the need for expensive instruments and intricate processing. The as-prepared arrays show excellent SERS activity and high reproducibility for Rhodamine 6G.
Ingram Katrin - - 2012
Although antischistosomal properties of peroxides were studied in recent years, systematic structure-activity relationships have not been conducted. We evaluated the antischistosomal potential of 64 peroxides belonging to bridged 1,2,4,5-tetraoxanes, alphaperoxides and β,δ-triketones. Thirty-nine compounds presented IC50 values < 15 µM on newly transformed schistosomula. Active drugs featured phenyl-, adamantane- or ...
Qu Sanyin - - 2012
A series of metal-free organic dyes that were bridged by a diketopyrrolopyrrole moiety and were composed of indoline and triphenylamine as donor groups and furan and benzene as conjugated spacer groups were designed and synthesized for use in dye-sensitized solar cells (DSCs). The photophysical properties, electrochemical properties, and performance of ...
Gupta Richa - - 2012
A novel, thermostable, alkalophilic β-D-galactosidase (Mbgl) was isolated from a metagenome of geothermal springs in northern Himalayan region of India. Mbgl was 447 amino acids in size and had conserved catalytic residues E170 and E358, indicating that it belonged to family 1 of glycosyl hydrolases showing maximum homology (89 %) with ...
Datiko Jallale - - 2012
Assessment of the anthelmintic (AH) utilisation practices and estimation of the prevalence of gastrointestinal helminth infections in sheep were carried out from November 2010 to April 2011 in urban and peri-urban areas of Bishoftu Town, central Ethiopia. A structured questionnaire was employed to assess the AH utilisation practices in sheep ...
Gursoy Hare - - 2012
OBJECTIVES: The purpose of this review was to summarize recent developments regarding photodynamic therapy (PDT) in the field of dentistry. MATERIALS AND METHODS: A review of pertinent literature was carried out in PubMED to determine the current position of PDT applications in dentistry. One hundred thirteen relevant articles were retrieved ...
Nomura Akihiro - - 2012
Aims: The aim of this study was to evaluate very long-term clinical outcomes and potential predictors after percutaneous coronary intervention (PCI) with bare metal stents (BMS) for unprotected left main coronary artery disease (ULMCAD). Methods and results: From March 1991 to August 2001, 151 patients who underwent PCI with BMS ...
Abdi Ibrahim Ali - - 2012
This study aimed to evaluate the level of knowledge concerning HIV transmission and the attitudes towards AIDS among a rural semi-nomadic community in Somaliland. Cross-sectional survey. Questionnaire-based interviews were conducted via a household survey in Sharmake, a village in the Hargeisa district, Somaliland. 141 adults living within 7 km of the ...
Xing Zhe - - 2012
The aim of this study was to compare the effect of different ratios of human umbilical vein endothelial cells (HUVECs) on osteogenic activity of human osteoblast-like cells (HOB) and capillary-like structure (CLS), seeded into copolymer scaffolds in a dynamic culture system. HOB and HUVEC were co-cultured into poly(L-lactide)-co-(1,5-dioxepan-2-one) [poly(LLA-co-DXO)] scaffolds ...
Xu Ming - - 2012
Monofunctional organic mercurials (MFOHgs) of different sizes and electronic properties were used to evaluate the accessibility of SH groups in intact proteins. The change in conformation of proteins, such as BLG and OVA, when treated with MFOHgs of increasing size was used as a measure of the accessibility of SH ...
Redelmeier Donald A DA Department of Medicine, University of Toronto, Toronto, ON, - - 2012
Physicians' warnings to patients who are potentially unfit to drive are a medical intervention intended to prevent trauma from motor vehicle crashes. We assessed the association between medical warnings and the risk of subsequent road crashes. We identified consecutive patients who received a medical warning in Ontario, Canada, between April ...
Mulligan Kimberly A KA Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94158, - - 2012
Members of the Wnt family of secreted signaling proteins influence many aspects of neural development and function. Wnts are required from neural induction and axis formation to axon guidance and synapse development, and even help modulate synapse activity. Wnt proteins activate a variety of downstream signaling pathways and can induce ...
Matsushita Akane - - 2012
The transcriptional activator WRKY45 plays a major role in the salicylic acid (SA)/benzothiadiazole-induced defense program in rice. Here, we show that the nuclear ubiquitin proteasome system (UPS) plays a role in regulating the function of WRKY45. Proteasome inhibitors induced accumulation of polyubiquitinated WRKY45 and transient upregulation of WRKY45 target genes ...
Lifford Kate J - - 2012
Women at high risk of familial ovarian cancer face a potentially difficult risk management choice between unproven ovarian cancer screening (OCS) and bilateral salpingo-oophorectomy (BSO). It is not fully understood why women who initially opt for OCS may later undergo BSO, nor what the impact of this may be. This ...
Zhang Rui - - 2012
In the search for an effective biocatalyst for the reduction of acetophenones with unprotected hydroxy group on the benzene ring, a microorganism, which reduced para-acetylphenol to S-(-)-1-(para-hydroxyphenyl)ethanol under anaerobic conditions, was isolated from soil samples and the 16S rDNA study showed that it was phylogenetically affiliated with species of the ...
Venkatramaiah N - - 2012
Herein we report a novel fluoranthene-based fluorescent fluorophore 7,10-bis(4-bromophenyl)-8,9-bis[4-(hexyloxy)phenyl]fluoranthene (S(3) ) and its remarkable properties in applications of explosive detection. The sensitivity towards the detection of nitroaromatics (NACs) was evaluated through fluorescence quenching in solution, vapor, and contact mode approaches. The contact mode approach using thin-layer silica chromatograp- hic plates ...
Linnek Jens - - 2012
From the branches of Pittosporum senacia Putterlick (Pittosporaceae), two new triterpenoid saponins, senaciapittosides A and B (1, 2), were isolated. Their structures were elucidated by extensive analysis of one- and two-dimensional nuclear magnetic resonance spectroscopy, high-resolution electrospray ionization mass spectrometry (HR-ESIMS) and chemical evidence as 3-O-[β- d-glucopyranosyl-(1 → 2)]-[α- l-arabinopyranosyl-(1 → 3)]-[α- l-arabinofuranosyl-(1 → 4)]-β- d-glucuronopyranosyl ...
Marchesini Victoria A - - 2012
Disturbances in semiarid environments have revealed a strong connection between water, salt and vegetation dynamics highlighting how the alteration of water fluxes can drive salt redistribution process and long-term environmental degradation. Here, we explore to what extent the reciprocal effect, that of salt redistribution on water fluxes, may play a ...
Cardenas-Rodriguez Magdalena - - 2012
Bardet-Biedl syndrome (BBS) is a genetically heterogeneous disorder that is generally inherited in an autosomal recessive fashion. However, in some families, trans mutant alleles interact with the primary causal locus to modulate the penetrance and/or the expressivity of the phenotype. CCDC28B (MGC1203) was identified as a second site modifier of ...
Zhao Ze-Kun - - 2012
The aim of this study was to investigate the expression of LSD1 in human hepatocellular carcinoma (HCC) cell lines and HCC samples. In this study, we examined LSD1 expression in 60 paired liver cancer tissues and adjacent noncancerous tissues by Western blot. In addition, we analyzed LSD1 expression in 198 ...
Strbian Daniel - - 2012
OBJECTIVES: To compare outcome of ischaemic stroke patients undergoing rescue endovascular procedure for proximal middle cerebral artery occlusion with matched patients without endovascular procedure after unsuccessful intravenous thrombolysis. METHODS: Endovascularly treated patients with middle cerebral artery occlusion (n = 41) were matched by propensity score with similar patients treated by intravenous thrombolysis ...
Suzuki Takayuki - - 2012
Localised brain tissue damage activates surrounding astrocytes, which significantly influences subsequent long-term pathological processes. Most existing focal brain injury models in rodents employ craniotomy to localise mechanical insults. However, the craniotomy procedure itself induces gliosis. To investigate perilesional astrocyte activation under conditions in which the skull is intact, we created ...
Yamamoto Takayuki - - 2012
PURPOSE: The aim of this study was to investigate the long-term effect of enteral nutrition (EN) as a maintenance therapy in Crohn's disease (CD) patients following surgery. METHODS: This study was an extension of our previous study to prolong the duration of intervention and follow-up from 1 to 5 years. Forty ...
Wang Xiuhong - - 2012
An improved single-drop microextraction (SDME) method combined with high performance liquid chromatography has been developed for the detection of trace carbamate and organophosphorus pesticides in water samples. The most fascinating feature of the proposed method is the use of an oval-shaped polychloroprene rubber (PCR) tube to load the extraction solvent, ...
Clark Vincent P - - 2012
Relapse presents a significant problem for patients recovering from stimulant dependence. Here we examined the hypothesis that patterns of brain function obtained at an early stage of abstinence differentiates patients who later relapse versus those who remain abstinent. Forty-five recently abstinent stimulant-dependent patients were tested using a randomized event-related functional ...
Goli Kiran K - - 2012
We describe the formation of amphiphilic polymeric assemblies via a three-step functionalization process applied to polypropylene (PP) nonwovens and to reference hydrophobic self-assembled n-octadecyltrichlorosilane (ODTS) monolayer surfaces. In the first step, denatured proteins (lysozyme or fibrinogen) are adsorbed onto the hydrophobic PP or the ODTS surfaces followed by cross-linking with ...
Ingram Verina V Centre for International Forestry Research (CIFOR), BP 2008, Messa, Yaoundé, Cameroon. - - 2013
Bamboo is a well know and versatile material, which is a common sight across Cameroon's diverse ecosystems, from dry to humid tropical and Afromontane forests. Its numerous uses range from storage jars to decorating restaurant-bars, beehives to knives, fences, fodder, and fuel. Responding to the paucity of data on species ...
Ng Ashley P - - 2012
Abstract The understanding of myeloproliferative neoplasms has changed dramatically since Dameshek proposed his classification over fifty years ago. Our knowledge of the types of cells which comprise the hematopoietic system and of how they are regulated has also appreciated significantly over this time. This review will relate what is currently ...
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