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Bittner Edward A - - 2012
Tracheostomy is one of the most commonly performed procedures in the ICU. Despite the frequency of the procedure, there remains controversy regarding selection of patients who should undergo tracheostomy, the optimal technique, timing of placement and decannulation, as well as impact on outcome associated with the procedure. A growing body ...
Potera Carol - - 2012
Cost-effectiveness is important in the current world economy.
Roberts V I - - 2012
Controversy surrounds the management of displaced three- and four-part fractures of the proximal humerus. The percutaneous Resch technique of stabilisation involves minimal soft-tissue dissection and a reduced risk of stiffness and avascular necrosis. However, it requires a second operation to remove Kirschner wires and the humeral block. We describe a ...
Spuls Ph I - - 2012
Aim  Papp et al. (N Engl J Med 2012; 366: 1181-9) and Leonardi et al. (N Engl J Med 2012; 366: 1190-9) respectively assessed the efficacy and safety of brodalumab (AMG 827), a human monoclonal antibody directed against interleukin (IL)-17RA, the receptor of IL-17A and ixekizumab (LY2439821), a humanized anti-IL-17 monoclonal antibody ...
Lake-Bakaar Geri A - - 2012
Objective-To describe clinical signs, treatment, and outcome of aortic thrombosis in dogs. Design-Retrospective case series. Animals-31 dogs with aortic thrombosis. Procedures-Records were retrospectively reviewed and data collected regarding signalment, historical signs, physical examination findings, laboratory testing, definitive diagnosis, and presence of concurrent disease. Results-The records of 31 dogs with clinical ...
Escobar L F - - 2012
A total of 11 types of glycogen storage disorders have been recognized with variable clinical presentations. Type IV, also known as Andersen disease, represents a rare subtype that can induce severe clinical findings early in life. We report on a patient with early fetal onset of symptoms with severe neuromuscular ...
Pulcini Joyce - - 2012
Here's what you need to know as the fall elections approach.
Sarrafian Tiffany L - - 2012
Objective-To determine major causes of death and the anatomic location of musculoskeletal injuries in Quarter Horse racehorses in California. Design-Retrospective case series. Animals-314 Quarter Horse racehorses with musculoskeletal injuries that were necropsied through the California Horse Racing Board Postmortem Program from 1990 to 2007. Procedures-Postmortem pathology reports were retrospectively reviewed. ...
Deborde Anne-Sophie - - 2012
Insecure attachment and the inability to identify emotions have both been put forward as possible explanations for dysfunction of the emotional system in borderline personality disorder (BPD). This study aimed to test a model according to which the influence of attachment on the development of BPD in adolescence is mediated ...
Hernandez Ana - - 2012
This study examines the relationship of different types of childhood maltreatment and the perceived parenting style with borderline personality disorder (BPD) criteria. Kendall's Tau partial correlations were performed controlling for the effect of simultaneous adverse experiences and Axis I and II symptoms in a sample of 109 female patients (32 ...
Fazel Seena - - 2012
Although perinatal factors are associated with the development of several psychiatric disorders, it is unknown whether these factors are linked with personality disorder. Cases of personality disorder were drawn from a national registry of all forensic psychiatric evaluations (n = 150). Two control groups were used: (1) A sample of ...
Conway Christopher - - 2012
With the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) scheduled for publication in 2013, researchers continue to debate the optimal classification of borderline personality disorder (BPD). Much of the discussion has focused on the relative merits of dimensional versus categorical classification schemes for BPD. Advances ...
Nedopil Norbert - - 2012
Forensic psychiatry was long regarded as sufficiently defined by the laws of a country to be restricted by national boundaries in all but a few areas. European Union (EU) employment rights and travel facilities have changed that within the EU. The goal of this research is to explore the role ...
Sebastian Lavanya - - 2012
Training pathways and structures in forensic psychiatry differ between European Union countries, and perspective may differ between trainees and trainers. To describe the context of forensic psychiatry training in the UK, with a particular emphasis on England and Wales, as well as some details of core psychiatry and specialist forensic ...
Gómez-Durán Esperanza L - - 2012
In some European countries, forensic psychiatric training is formalised within a psychiatric framework. In others, the approach is radically different, but the end result may be a practitioner who is qualified to practise forensic psychiatry in all European jusrisdictions. The aim of this study is to describe the context of ...
Kitada Kento - - 2012
1. Aldosterone has been shown to mediate p21-dependent cellular senescence in rat kidney proximal tubules in vivo and in cultured human proximal tubular cells. The p21-induced senescent cells express higher levels of apoptotic cytokines, such as tumour necrosis factor (TNF)-α compared with non-senescent cells. The aim of the present study ...
Beck Roy W - - 2012
Although developed to be a management tool for individuals with diabetes, continuous glucose monitoring (CGM) also has potential value for the assessment of outcomes in clinical studies. We evaluated using CGM as such an outcome measure. Data were analyzed from six previously completed inpatient studies in which both CGM (Freestyle ...
Cote Michele L - - 2012
To describe the pattern and frequency of oncogene mutations in white and African American women with endometrial cancer and to determine if racial differences in oncogene mutations exist among women with pathologically similar tumors. Patients with endometrial cancer from a large urban hospital were identified through medical records, and representative ...
Silverman Merav H - - 2012
The objectives of this study were to assess the rates of comorbid anxiety disorders other than PTSD in patients with borderline personality disorder (BPD) and Axis II comparison subjects over ten years of prospective follow-up and to determine time-to-remission, recurrence, and new onset of these disorders. The SCID I was ...
Wei Hua - - 2012
Adaptation of in vitro optimized polymeric gene delivery systems for in vivo use remains a significant challenge. Most in vivo applications require particles that are sterically stabilized, which significantly compromises transfection efficiency of materials shown to be effective in vitro. We present a multifunctional well-defined block copolymer that forms particles ...
Modugno Francesmary - - 2012
To review the current understanding of the underlying molecular, biologic, and genetic mechanisms involved in ovarian cancer development and how these mechanisms can be targets for prevention, detection, and treatment of the disease and its recurrence. In May 2012, we convened a meeting of researchers, clinicians, and consumer advocates to ...
Benin Andrea L - - 2012
The objective of this study was to qualitatively describe the impact of a Rapid Response Team (RRT) at a 944-bed, university-affiliated hospital. We analysed 49 open-ended interviews with administrators, primary team attending physicians, trainees, RRT attending hospitalists, staff nurses, nurses and respiratory technicians. Themes elicited were categorised into the domains ...
Goethals Kris - - 2012
The Ghent Group - a group of European forensic psychiatrists - has discussed ways of informing fellow professionals and the wider public about their difficult and frequently misunderstood discipline, agreeing that the specialty may have to be 'sold' to those who pay for it and use it. Our aim was ...
Subramaniam Ramesh - - 2012
Rice body formation is a nonspecific response to chronic synovial inflammation associated with tuberculous arthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, seronegative inflammatory arthritis, and even osteoarthritis. Such bodies were termed rice bodies because of their close resemblance to grains of polished white rice. We present a case report of a ...
Lahti Marius M Institute of Behavioural Sciences, University of Helsinki, Helsinki, Finland. - - 2012
We have previously shown that the temporary separation of Finnish children from both parents during World War II predicted any serious mental, substance use, and personality disorders in adulthood. Here we examine if parental separation is a specific vulnerability factor for any- and dramatic personality disorders relative to other mental ...
Hopwood Christopher J CJ Department of Psychology, Michigan State University, East Lansing, MI 48824-1116, USA. - - 2012
Zanarini and colleagues have proposed that hyperbolic temperament, involving a preponderance of negative emotions and cognitions combined with a need for those dysphoric inner states to be validated and understood, underlies borderline symptomatology. This study examined neuroticism and childhood maltreatment as predictors of hyperbolic features measured 10 years later in ...
Cross M B MB Hospital for Special Surgery, 535 East 70th Street, New York, New York 10021, USA. - - 2012
The purpose of this study was to compare the amount of acetabular bone removed during hip resurfacing (HR) and cementless total hip replacement (THR), after controlling for the diameter of the patient's native femoral head. Based on a power analysis, 64 consecutive patients (68 hips) undergoing HR or THR were ...
Bergenstal Richard M RM International Diabetes Center at Park Nicollet , Minneapolis, Minnesota 55416, USA. - - 2012
This study evaluated whether education and use of the advanced meter features of the CONTOUR(®) (Bayer HealthCare LLC, Diabetes Care, Tarrytown, NY) blood glucose monitoring system (BGMS) affect the frequency and pattern of blood glucose testing in insulin-using subjects with diabetes who routinely perform self-monitoring of blood glucose (SMBG). Insulin-using ...
Hewitt Stephen - - 2012
BACKGROUND: The prevalence of secondary hyperparathyroidism (SHPT) is high after bariatric surgery. Vitamin D is supplied to counteract SHPT and bone disease, and we studied vitamin D associations with SHPT. METHODS: We measured serum levels of 25-OH vitamin D and parathyroid hormone (PTH) 5 years after gastric bypass and duodenal switch. ...
Hessmann M H - - 2012
OBJECTIVE: Anatomical reduction of two- to four-part fractures of the proximal humerus using indirect reduction techniques. Intramedullary fixation with a short humerus nail. Restoration of a stable bone-implant construct that enables early functional after-treatment. INDICATIONS: Displaced and unstable two- to four-part fractures of the proximal humerus. Fractures of the proximal ...
Lämmer A B - - 2012
The differential diagnosis of focal neuropathy continues to be one of the main tasks in peripheral neurology and clinical neurophysiology. In this respect a detailed medical history a topologically oriented clinical examination based on profound anatomical knowledge and a targeted neurophysiological examination are the cornerstones of successful diagnosis. Refined imaging ...
Kleinschnitz C - - 2012
In Germany, as in most other industrialized countries, ischemic stroke is the leading cause of disability and the third leading cause of death. As the incidence of ischemic stroke increases with age it is expected that this problem will become even more urgent in an aging society. Despite significant research ...
Dresing K - - 2012
OBJECTIVE: The primary aim of minimally invasive osteosynthesis (MIO) is the anatomical reconstruction of the distal tibial articular surface, with preservation of the soft tissue to allow early functional postoperative management. This should lead to a normal bone healing and recovery without arthrosis. INDICATIONS: Fractures type Rüedi I + II or AO 43-B1, ...
Chaisuparat Risa - - 2012
Ribosomal protein S6 (RPS6), a downstream effector of the mammalian target of rapamycin pathway (mTOR), is activated in many cancers including oral squamous cell carcinoma (OSCC). However, the role of RPS6 in the progression of potentially malignant disorders (or premalignant lesions) to OSCC is unknown. The purpose of this study ...
- - 2012
An estimated 25,000 infants are born to hepatitis B surface antigen (HBsAg)-positive women annually in the United States. With no intervention, 40%-90% of these infants will acquire hepatitis B virus (HBV) infection. Approximately 90% of infected infants develop chronic HBV infection, with a 15%-25% risk for premature death from cirrhosis ...
- - 2012
Influenza vaccination of health-care personnel (HCP) is recommended by the Advisory Committee on Immunization Practices (ACIP). Vaccination of HCP can reduce morbidity and mortality from influenza and its potentially serious consequences among HCP, their family members, and their patients. To provide timely estimates of influenza vaccination coverage and related data ...
- - 2012
Since July 2012, 305 cases of infection with influenza A (H3N2) variant (H3N2v) virus containing the influenza A (H1N1)pdm09 M gene have occurred in multiple U.S. states, primarily associated with swine exposure at agricultural fairs. In Ohio, from July 28 to September 25, 2012, a total of 106 confirmed H3N2v ...
Thomalla G - - 2012
Patients waking up with stroke symptoms are generally excluded from intravenous thrombolysis. It was shown that magnetic resonance imaging (MRI) can identify patients within the time window for thrombolysis (≤ 4.5 h from symptom onset) by a mismatch between the acute ischemic lesion visible on diffusion-weighted imaging (DWI) but not visible on ...
Ehara Shoichi - - 2012
Although atrial natriuretic peptide (ANP) is widely used in patients with congestive heart failure (CHF), little is known about its effect on epicardial coronary arteries. Magnetic resonance imaging (MRI) enables precise measurement of coronary vasodilation and flow velocity. In this study, we examined the changes in epicardial coronary artery size ...
- - 2012
Pregnant women and their newborns are at elevated risk for influenza-associated hospitalization and death. The Advisory Committee on Immunization Practices (ACIP) and the American College of Obstetricians and Gynecologists (ACOG) have recommended influenza vaccination for all women who are or will be pregnant during the influenza season, regardless of trimester. ...
Greiner M - - 2012
BACKGROUND: The optimal strategy to prevent cytomegalovirus (CMV) disease after kidney transplantation continues to be open to debate. The preemptive approach requires regular determination of CMV viremia and prompt initiation of therapy. METHODS: We retrospectively compared the incidence of CMV disease during two periods at our center: A first phase ...
Gualtieri William - - 2013
The purpose of this study is to present the first case of a pure 'topiramate maculopathy' without acute glaucoma and/or myopia, which form the classical syndrome. Interventional/observational case report. Institutional University Teaching Hospital. A 22-year-old American female, after taking 100 mg of topiramate (Topamax®) a day for 6 days because ...
Moolla Zaheer - - 2012
BACKGROUND: The etiology of acute pancreatitis can be difficult to determine early in the course of the disease. The aim of the present study was to determine the relationship between biochemical parameters and the cause of acute pancreatitis. METHODS: A prospectively collected database of patients admitted with acute pancreatitis between ...
Kandoth Noufal - - 2012
Herein we report the design, preparation, and properties of a supramolecular system based on a tailored nitric oxide (NO) photodonor and a rhodamine-labeled β-cyclodextrin conjugate. The combination of spectroscopic and photochemical experiments shows the absence of significant interchromophoric interactions between the host and the guest in the excited states. As ...
Nagorny Cecilia - - 2012
Circadian rhythms are ubiquitous in biological systems and regulate metabolic processes throughout the body. Misalliance of these circadian rhythms and the systems they regulate has a profound impact on hormone levels and increases risk of developing metabolic diseases. Melatonin, a hormone secreted by the pineal gland, is one of the ...
Puls Miriam - - 2012
Aims: Transcatheter aortic valve implantation (TAVI) has recently developed into an accepted alternative to conventional surgery in high-risk patients. According to current data, post-TAVI prosthetic valve endocarditis (PVE) seems to occur very rarely. Methods and results: We followed the first 180 consecutive patients who underwent TAVI at our institution to ...
Melo Saulo Maia d'Avila - - 2012
BACKGROUND: There is an increased prevalence of asthmatic, obese patients undergoing bariatric surgery. The objective of our study is to evaluate the severity, level of control, respiratory medication use, and time required for prebariatric surgery asthma control. METHODS: This is a prospective study in which 88 obese asthmatics were evaluated ...
Stewart Alex G - - 2012
The Society for Environmental Geochemistry and Health (SEGH) is a forum for multidisciplinary interaction relating the geochemical environment to health. With national funding, SEGH identified collaborative opportunities through the MULTITUDE series of workshops (2007-2011). We reviewed the meetings by electronic questionnaire (39 % response). Smaller meetings saw most returning delegates, suggesting ...
Giannini Sandro - - 2012
PURPOSE: Knee arthrodesis is a scarcely tolerated procedure with a strong negative impact on the quality of life of the patient. The use of a fresh osteochondral allograft represents a fascinating option for a biological joint reconstruction. Aim of this report is to describe a case of total femoral and ...
Ugolini Alberto - - 2012
This study evaluates the use of the sandhopper Talitrus saltator as a bioindicator of PAHs contamination of the supralittoral zone of sandy beaches. Adult amphipods were collected at eight localities on the Tuscany shore in summer. Concentrations of 16 PAHs indicated as priority pollutants by the Environmental Protection Agency were ...
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