Search Results
Results 51 - 100 of 2252
1 2 3 4 5 6 7 8 9 10 >
Raphel Jordan - - 2012
Photocrosslinkable, protein-engineered biomaterials combine a rapid, controllable, cytocompatible crosslinking method with a modular design strategy to create a new family of bioactive materials. These materials have a wide range of biomedical applications, including the development of bioactive implant coatings, drug delivery vehicles, and tissue engineering scaffolds. We present the successful ...
Mazzone Jennifer R - - 2012
A synthetic approach to the papyracillic acid family of natural products has been developed. The spiroacetal core is rapidly assembled through an unprecedented zinc carbenoid-mediated tandem chain extension-acylation reaction. Subsequent functional group manipulation provided access to papyracillic acid B and 4-epi-papyracillic acid C. The successful preparation of these molecules resulted ...
Noël Stéphanie M - - 2012
Objective-To compare values of lower urogenital tract urodynamic and morphometric variables determined during the prepubertal (sexually immature) period and first and second estrous cycles in healthy female Beagle littermates to determine functional and anatomic changes of the lower urogenital tract during those periods. Animals-5 female Beagle littermates. Procedures-Urethral pressure profilometry, ...
Shen Yufei - - 2012
This study investigated the involvement of fibrillar collagen in remodeling extracellular matrices (ECM) and its significant impact on the metastasis/invasion of epithelial ovarian cancer cells via β1 integrin/phosphatase and tensin homolog (PTEN) signaling. Normal ovarian surface epithelium tissues (n = 13), ovarian cancer tissues (n = 28), ovarian cancer cell ...
Pijls B G - - 2012
This single-blinded randomised controlled trial investigated whether one design of mobile-bearing (MB) total knee replacement (TKR) has any advantage over a fixed-bearing (FB) design on long-term fixation as measured by radiostereometry. The amount of wear underneath the mobile bearing was also evaluated. A series of 42 knees was randomised to ...
Tinkler Stacy H - - 2012
Objective-To determine whether plasma total CO(2) concentrations would vary with the size of the evacuated tube used to collect blood samples. Design-Randomized crossover study. Animals-Convenience sample of 20 healthy adult horses. Procedures-Jugular venous blood was collected from horses in random order into 8 types of evacuated tubes: 2-mL glass, 2- ...
Ashton Michael C - - 2012
The Personality Inventory for DSM-5 (PID-5), a new measure of maladaptive personality traits, has recently been developed by the DSM-5 Personality and Personality Disorders Workgroup. The PID-5 variables were examined within the seven-factor space defined by the six HEXACO factors and the Schizotypy/Dissociation factor (Ashton & Lee, 2012) using participant ...
Harris Tim - - 2012
Severe trauma is an increasing global problem mainly affecting fit and healthy younger adults. Improvements in the entire pathway of trauma care have led to improvements in outcome. Development of a regional trauma system based around a trauma centre is associated with a 15-50% reduction in mortality. Trauma teams led ...
Tsirikos A I - - 2012
An eight-week-old boy developed severe thoracic spondylodiscitis following pneumonia and septicaemia. A delay in diagnosis resulted in complete destruction of the T4 and T5 vertebral bodies and adjacent discs, with a paraspinal abscess extending into the mediastinum and epidural space. Antibiotic treatment controlled the infection and the abscess was aspirated. ...
Wygant Dustin B - - 2012
The current study examined the association between domains from the Personality Psychopathology Five (PSY-5; Harkness & McNulty, 1994) model, which is a dimensional model of pathological personality that corresponds closely to the proposed domains of the DSM-5, and psychopathy as indexed by the Psychopathy Checklist-Screening Version (PCL-SV; Hart, Cox, & ...
Angelos John A - - 2012
Objective-To evaluate efficacy of a recombinant Moraxella bovis pilin-cytotoxin-Moraxella bovoculi cytotoxin subunit vaccine to prevent naturally occurring infectious bovine keratoconjunctivitis (IBK). Animals-107 beef steers. Procedures-2 groups of calves were inoculated SC with an immunostimulating complex (ISCOM) matrix adjuvant (control group; n = 54) or a recombinant M bovis pilin-cytotoxin-M bovoculi ...
Larsson Gabriella Lillsunde - - 2012
To investigate the human papillomavirus (HPV) and HPV type 16-variant distribution in a series of vulvar squamous cell carcinomas (VSCC) and to evaluate the impact of HPV and HPV 16-variant on prognosis. A series of 133 patients who had a diagnosis of VSCC (1983-2008) was selected for the study. Detection ...
Jaiswal P K - - 2012
We analysed whether a high body mass index (BMI) had a deleterious effect on outcome following autologous chondrocyte implantation (ACI) or matrix-carried autologous chondrocyte implantation (MACI) for the treatment of full-thickness chondral defects of the knee from a subset of patients enrolled in the ACI vs MACI trial at The ...
Adkesson Michael J - - 2012
Objective-To determine the pharmacokinetics of a long-acting formulation of ceftiofur, ceftiofur crystalline-free acid (CCFA), following SC injection to Asian elephants (Elephas maxim us). Animals-11 adult Asian elephants. Procedures-Each elephant received CCFA (6.6 mg/kg, SC) in the area caudoventral to the base of an ear. Blood samples were collected from an ...
Cohen Noah D - - 2012
Objective-To determine whether the concentration of airborne virulent Rhodococcus equi varied by location (stall vs paddock) and month on horse farms. Sample-Air samples from stalls and paddocks used to house mares and foals on 30 horse breeding farms in central Kentucky. Procedures-Air samples from 1 stall and 1 paddock were ...
Sarmah S S - - 2012
Radiological assessment of total and unicompartmental knee replacement remains an essential part of routine care and follow-up. Appreciation of the various measurements that can be identified radiologically is important. It is likely that routine plain radiographs will continue to be used, although there has been a trend towards using newer ...
Macintyre Neil R - - 2012
The ventilator discontinuation process is an essential component of overall ventilator management. Undue delay leads to excess stay, iatrogenic lung injury, unnecessary sedation, and even higher mortality. On the other hand, premature withdrawal can lead to muscle fatigue, dangerous gas exchange impairment, loss of airway protection, and also a higher ...
Duesterdieck-Zellmer Katja F - - 2012
Objective-To determine concentration-dependent effects of tiludronate on cartilage explants incubated with or without recombinant equine interleukin-1β (rEq IL-1). Sample-Articular cartilage explants from the femorotibial joints of 3 young adult horses. Procedures-Cartilage explants were incubated with 1 of 6 concentrations (0, 0.19, 1.9, 19, 190, or 1,900 mg/L) of tiludronate and ...
Yu Rongqin - - 2012
The risk of antisocial outcomes in individuals with personality disorder (PD) remains uncertain. The authors synthesize the current evidence on the risks of antisocial behavior, violence, and repeat offending in PD, and they explore sources of heterogeneity in risk estimates through a systematic review and meta-regression analysis of observational studies ...
Mattila M - - 2012
We compared the clinical, radiological and quality-of-life outcomes between hybrid and total pedicle screw instrumentation in patients undergoing surgery for neuromuscular scoliosis. A matched comparison using prospectively collected data was undertaken. A total of 66 patients underwent posterior or anteroposterior correction and fusion with hybrid (n = 33, mean age at surgery ...
Diana Alessia - - 2012
Objective-To noninvasively assess the influence of ingestion of a standard meal on gallbladder volume (GBV) in healthy cats. Animals-10 healthy adult domestic shorthair cats (4 neutered females, 5 neutered males, and 1 sexually intact male). Procedures-Nonsedated cats were positioned in dorsal and left lateral recumbency to obtain ultrasonographic measurements of ...
Hughes S P F - - 2012
This article reviews the current knowledge of the intervertebral disc (IVD) and its association with low back pain (LBP). The normal IVD is a largely avascular and aneural structure with a high water content, its nutrients mainly diffusing through the end plates. IVD degeneration occurs when its cells die or ...
Park Sol-Ji - - 2012
Abstract Aberrant epigenetic nuclear reprogramming of somatic nuclei is a major cause of low success in cloning. It has been demonstrated that treatment of histone deacetylase inhibitors (HDACi) enhances developmental potential of somatic cell nuclear transfer (SCNT) embryos by alteration of epigenetic status. The aim of the present study was ...
Gulland Frances M D - - 2012
Objective-To determine the effect of natural exposure to domoic acid (DA) on eosinophil counts and adrenal gland function in California sea lions (Zalophus californianus). Design-Cross-sectional prospective study. Animals-39 California sea lions. Procedures-Adult female sea lions admitted to a rehabilitation hospital during 2009 were classified into 1 of 3 groups (acute ...
Mullins-Sweatt Stephanie N - - 2012
One of the official proposals for the fifth edition of the American Psychiatric Association's (APA) diagnostic manual (DSM-5) is to delete half of the existing personality disorders (i.e., dependent, histrionic, narcissistic, paranoid, and schizoid). Within the APA guidelines for DSM-5 decisions, it is stated that there should be expert consensus ...
Borer-Weir Kate E - - 2012
Objective-To evaluate a human radioimmunoassay (RIA) and equine and high-range porcine (hrp) species-specific ELISAs for the measurement of high serum insulin concentrations in ponies. Samples-Serum samples from 12 healthy nonobese ponies (7 clinically normal and 5 laminitis prone; 13 to 26 years of age; 11 mares and 1 gelding) before ...
- - 2012
Osteoporosis is common and the health and financial cost of fragility fractures is considerable. The burden of cardiovascular disease has been reduced dramatically by identifying and targeting those most at risk. A similar approach is potentially possible in the context of fragility fractures. The World Health Organization created and endorsed ...
Sarmiento E - - 2012
Infection remains a source of mortality in heart recipients. We previously reported that post-transplant immunoglobulin G (IgG) quantification can help identify the risk for infection. We assessed whether other standardized parameters of humoral and cellular immunity could prove useful when identifying patients at risk of infection. We prospectively studied 133 ...
Mayhew Philipp D - - 2012
Objective-To describe a technique and evaluate the outcome of thoracoscopic thoracic duct ligation (TDL) and subphrenic pericardiectomy (SPP) for treatment of idiopathic chylothorax (IC) in dogs. Design-Retrospective case series. Animals-6 client-owned dogs. Procedures-Medical records of dogs with a diagnosis of IC that were subsequently treated by thoracoscopic TDL and SPP ...
Khanduja V - - 2012
The FRCS (Tr & Orth) examination has three components: MCQs, Vivas and Clinical Examination. The Vivas are further divided into four sections comprising Basic Science, Adult Pathology, Hands and Children's Orthopaedics and Trauma. The Clinical Examination section is divided into Upper and Lower limb cases. The aim of this section ...
Brandt J S - - 2012
A 41-year-old pregnant African-American woman noticed rapid growth of her cesarean delivery skin scar beginning at 14-week gestation. Skin biopsy, which was performed at 31 weeks, revealed poorly differentiated cutaneous melanoma. At 34 weeks, she underwent repeat cesarean delivery with tumor excision, pelvic lymphadenectomy and abdominal wall reconstruction. Locally advanced ...
Berghuis Han - - 2012
The distinction between general personality dysfunctioning (GPD) and specific personality traits (SPT) is an important focus of attention in the proposed revisions of the DSM-5. The present study explores the distinction between GPD and SPT using the self-report questionnaires General Assessment of Personality Disorder (GAPD) and Severity Indices for Personality ...
Beal Eileen - - 2012
If a picture is worth a thousand words, what's a YouTube video worth?
Erfourth Todd M - - 2012
Objective-To evaluate changes in serial hemograms and serum biochemical profiles in tumor-bearing dogs undergoing daily anesthesia with propofol as an induction agent for radiation therapy. Design-Retrospective case series. Animals-31 dogs with cutaneous or subcutaneous malignancies over the trunk or limbs. Procedures-Radiation therapy consisted of 18 daily treatments administered Monday through ...
Lam W-L - - 2012
This study was designed to test the hypothesis that the sensory innervation of bone might play an important role in sensing and responding to low-intensity pulsed ultrasound and explain its effect in promoting fracture healing. In 112 rats a standardised mid-shaft tibial fracture was created, supported with an intramedullary needle ...
Deluca L - - 2012
This is a case of a neonate born with a respiratory acidosis with a compensatory metabolic alkalosis. This case demonstrates placental physiology of gas exchange as well as the blunted ventilatory response in the neonate from chronic hypercapnia.
Yamamoto Daisuke - - 2012
Matrix metalloproteinase (MMP)-2 plays an important role in tissue remodelling during peritoneal injury caused by peritoneal dialysis (PD), but MMP-2 inhibitors have not yet been used clinically. Recently, it was reported that captopril, an angiotensin-converting enzyme inhibitor (ACEI), can inhibit MMP-2. To investigate the potential usefulness of ACEI during PD, ...
O'Kell Allison L - - 2012
Objective-To determine the effects of oral prednisone administration with or without ultralow-dose acetylsalicylic acid on coagulation parameters in healthy dogs and to assess intraindividual variation in thromboelastography results. Animals-14 healthy research dogs and 10 healthy client-owned dogs. Procedures-In a randomized controlled trial, research dogs underwent thromboelastography twice (3 days apart), ...
Carter David - - 2012
As sports programs are being cut, active commuting might fill the gap.
Chassanidis C G - - 2012
Periosteum is important for bone homoeostasis through the release of bone morphogenetic proteins (BMPs) and their effect on osteoprogenitor cells. Smoking has an adverse effect on fracture healing and bone regeneration. The aim of this study was to evaluate the effect of smoking on the expression of the BMPs of ...
Cummings C L - - 2012
Parental counseling becomes complex when considering the use of emerging technologies, especially if it is unclear whether the level of evidence is sufficient to transform the proposed therapy into accepted practice. This paper addresses ethical issues underlying medical decision-making and counseling in the setting of emerging treatments, when long-term outcomes ...
Paes Bosco A - - 2012
Pulmonary thromboembolism (PTE) is rare in neonates and infants; however evidence suggests it is underdiagnosed. The primary objective is to conduct a scientific review to determine if the presentation, diagnosis, treatment and outcomes of neonates and infants with PTE are consistent across studies. Secondly, to develop an algorithm to establish ...
Frampton Susan - - 2012
Those who know the patient best can help bridge the gap between hospital and home.
Gatineau Matthieu - - 2012
Objective-To compare effects of sterilization with hydrogen peroxide gas plasma (HPGP), ethylene oxide, and steam on bioadhesive properties of nylon and polyethylene lines used for stabilization of canine stifle joints. Sample-Samples of a 36.3-kg test nylon leader line, 57.8-kg test nylon fishing line, and 2-mm ultrahigh-molecular weight polyethylene (UHMWPE) were ...
Komzák M - - 2012
The biomechanical function of the anteromedial (AM) and posterolateral (PL) bundles of the anterior cruciate ligament (ACL) remains controversial. Some studies report that the AM bundle stabilises the knee joint in anteroposterior (AP) translation and rotational movement (both internal and external) to the same extent as the PL bundle. Others ...
Bendon C L - - 2012
Injectable collagenase is an alternative to surgical treatment for Dupuytren's disease. Previous studies have reported on the effectiveness of collagenase in finger contractures. This prospective study reports on the short-term safety and efficacy of collagenase treatment in five thumb and first web space Dupuytren's contractures. The thumb and first web ...
Bolwell Charlotte F - - 2012
Objective-To investigate the effect of exercise during yearling sales preparation on the risk of interruptions during training in Thoroughbred racehorses. Animals-114 Thoroughbred racehorses. Procedures-Information regarding the daily exercise of yearlings during sales preparation was obtained prospectively from a convenience sample of stud farms. Yearlings were followed to entry into race ...
Namba R S - - 2012
We examined patient and surgical factors associated with deep surgical site infection (SSI) following total hip replacement (THR) in a large integrated healthcare system. A retrospective review of a cohort of primary THRs performed between 2001 and 2009 was conducted. Patient characteristics, surgical details, surgeon and hospital volumes, and SSIs ...
Hess Dean R - - 2012
In recent years, there has been increasing interest in the use of noninvasive ventilation (NIV) in the post-extubation period to shorten the length of invasive ventilation, to prevent extubation failure, and to rescue a failed extubation. The purpose of this review is to summarize the evidence related to the use ...
Makarov M R - - 2012
We undertook a retrospective analysis of 306 procedures on 233 patients, with a mean age of 12 years (1 to 21), in order to evaluate the use of somatosensory evoked potential (SSEP) monitoring for the early detection of nerve compromise during external fixation procedures for limb lengthening and correction of ...
1 2 3 4 5 6 7 8 9 10 >