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Results 601 - 650 of 2252
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Antón-Pérez Gloria - - 2012
Approximately 4%-10% of incident patients on dialysis have a non-functioning kidney graft, and according to series, as many as 32% require transplantectomy for a variety of reasons. Mortality in these patients is significantly higher than in those with a functioning graft or on renal replacement therapy without having received a ...
Erdmann Markus - - 2012
The vicinal frustrated P/B Lewis pair (FLP) Mes(2)PCH(2)CH(2)B(C(6)F(5))(2) reacts with 9-borabicyclo[3.3.1]nonane (9-BBN) by C(6)F(5)vs. H exchange at boron to give the new [B]-H functionalized FLP Mes(2)PCH(2)CH(2)B(H)(C(6)F(5)) () and 9-C(6)F(5)-BBN. The latter was characterized as an isonitrile adduct by X-ray diffraction. The new FLP forms an adduct with pyridine and it ...
Combes Stephanie L - - 2012
This study aimed to estimate HIV incidence among women at higher HIV risk in Addis Ababa, Ethiopia using cross-sectional data. To refine the estimate, we sought to determine a local correction factor by estimating a false recent rate for the BED assay. The overall study had two parallel phases: cross-sectional ...
Jiang Xin-Dong - - 2012
Utilizing bulky bidentate ligand systems with C(2)F(5) and n-C(3)F(7) groups, antiapicophilic arsoranes (5b and 5c, respectively) were synthesized. A kinetic study on the isomerization of these arsoranes to their more stable isomers showed that the barriers increased in the order of CF(3) < C(2)F(5) < n-C(3)F(7) in accord with their ...
Gatz Christiane - - 2012
The plant immune system encompasses an arsenal of defense genes that is activated upon recognition of a pathogen. Appropriate adjustment of gene expression is mediated by multiple interconnected signal transduction cascades which finally control the activity of transcription factors. These sequence specific DNA binding proteins act at the interface between ...
Yoshidome Takashi - - 2012
A clue to the physical origin of the hydrophobicity is in the experimental observations, which show that it is weakened at low temperatures. By considering a solvophobic model protein immersed in water and three species of simple solvents, we analyze the temperature dependence of the changes in free energy, energy, ...
Huang Hui - - 2012
The melanocortin-4 receptor (MC4R) is a critical regulator of energy homeostasis, and has emerged as a premier target for obesity treatment. Numerous mutations in transmembrane domain 6 (TM6) of MC4R resulting in functional alterations have been identified in obese patients. Several mutagenesis studies also provided some data suggesting the importance ...
Liu Hongguang - - 2012
We provide a novel strategy to eliminate the epoxy group from the basal plane of graphene platelets. Given that the current reduction methods are unsatisfactory to clean the epoxides or sometimes cause undesirable structure deformations, the proposed strategy restores the original hexagonal carbon network without creating other new defects. To ...
Lin Chia-Cheng - - 2012
BACKGROUND: There is increasing evidence showing that hepatic resection is probably the best definitive treatment for unilateral hepatolithiasis. However, the role of hepatic resection for bilateral hepatolithiasis is rarely mentioned in the literature. METHODS: We retrospectively reviewed 197 patients who underwent hepatic resection for hepatolithiasis in Changhua Christian Hospital from ...
Spiesser Thomas W - - 2012
The cell division cycle orchestrates cellular growth and division. The machinery underpinning the cell division cycle is well characterised, but the actual cue(s) driving the cell division cycle remains unknown. In rapidly growing and dividing yeast cells, this cue has been proposed to be cell size. Presumably, a mechanism communicating ...
Kobashigawa J - - 2012
BACKGROUND: Cytomegalovirus (CMV) causes several complications following cardiac transplantation including cardiac allograft vasculopathy. Previous studies suggested that immunosuppressive treatment based on everolimus might reduce CMV infection. Aiming to better characterize the action of everolimus on CMV and its interplay with patient/recipient serology and anti-CMV prophylaxis, we analyzed data from 3 ...
Ghosh S - - 2012
A teenager who acquired 2009 H1N1 influenza A lower respiratory tract infection during total bone marrow and lymphoid aplasia, in the setting of human leukocyte antigen-haploidentical hematopoietic stem cell transplantation, was successfully treated with intravenous zanamivir. This case demonstrates efficient control of pandemic influenza infection by intravenous zanamivir in the ...
Semple Sean - - 2012
OBJECTIVE: To compare the response of a new particle counting instrument (Dylos DC1700) with that produced by a device (TSI Sidepak Personal Aerosol Monitor AM510) commonly used to measure PM(2.5) in settings where secondhand smoke (SHS) is encountered. METHODS: Controlled chamber experiments with different SHS concentrations were generated by burning ...
Asseburg Christian - - 2012
Background: The cost-effectiveness of triptans in the treatment of migraine has not been assessed since generic sumatriptan entered the Finnish market in 2008. Methods: Using systematic review and mixed treatment comparison, the effectiveness of triptans was estimated with regard to 2-hour response, 2-hour pain-free, recurrence, and any adverse event, using ...
Owen William R - - 2012
Facial telangiectases are small dilated vessels that are visible on the skin surface. They are a cosmetic disfigurement for millions of people, making their treatment one of the most frequently requested procedures in dermatology. Several treatment choices are available, including a variety of lasers. The purpose of this study was ...
Rytych Jennifer L - - 2012
Iron deficiency is common throughout the world and has been linked to cognitive impairments. Using neonatal piglets to model human infants, we assessed the impact of iron deficiency on spatial learning and memory. Artificially reared piglets were fed 1 of 3 liquid diets with varying concentrations of iron: control (CON), ...
Gusyev M A - - 2012
Noxious weeds threaten the Sheyenne National Grassland (SNG) ecosystem and therefore herbicides have been used for control. To protect groundwater quality, the herbicide application is restricted to areas where the water table is less than 10 feet (3.05 m) below the ground surface in highly permeable soils, or less than ...
Todorovic Ana - - 2012
Repetition of a stimulus, as well as valid expectation that a stimulus will occur, both attenuate the neural response to it. These effects, repetition suppression and expectation suppression, are typically confounded in paradigms in which the nonrepeated stimulus is also relatively rare (e.g., in oddball blocks of mismatch negativity paradigms, ...
Davidson Fiona - - 2012
OBJECTIVE: This paper outlines the process of implementation of a dialectical behavioral therapy (DBT) informed treatment for Australian Deaf mental health consumers. METHOD: The pilot project team members adapted DBT materials for the Australian Deaf population. Feedback was obtained from the pilot participants and modifications made during the pilot. Participant ...
Parra Eduardo - - 2012
Background: At present, there is no adequate system available for evaluating dialysis centres. Objectives: To construct an overall haemodialysis results weighting system, acceptable to the different stakeholders involved which allows the comparison of centres using a compound marker. Method: The Quality Management Work Group of the Spanish Society of Nephrology ...
Pfluger Courtney - - 2012
While it has been shown that cells respond to topographical cues, most studies of the influence of topography have been restricted to culture substrates with regular, single-scale features, such as grooves. In contrast, in vivo topography is highly complex, irregular, and multi-scale. In this work, we demonstrate the use of ...
Bluestone Charles D - - 2012
We hypothesize that if otitis media is most likely primarily a human disease due to consequences of evolution, rhinosinusitis may also be limited to humans for similar reasons. If otitis media, with its associated hearing loss, occurred in animals in the wild, they probably would have been culled out by ...
Debu A - - 2012
Folliculotropic Mycosis Fungoides (FMF) is an unusual clinicopathological variant of Mycosis Fungoides (MF) often resistant to standard therapies(1) . Accordingly, a pilot study was designed to assess the efficacy of photodynamic therapy (PDT) on specific lesions of FMF with emphasis on lesions, either refractory or not, located on face and ...
Nguyen P - - 2012
Mapping disease risk often involves working with data that have been spatially aggregated to census regions or postal regions, either for administrative reasons or confidentiality. When studying rare diseases, data must be collected over a long time period in order to accumulate a meaningful number of cases. These long time ...
Obora Yasushi - - 2012
Iridium-catalyzed alkylation of methylquinolines at the methyl substituent was achieved using alcohols as alkylating agents. The reaction proceeded through a transfer hydrogenation pathway from the alcohol to the Ir complex, affording an aldehyde and Ir-H species, followed by base-assisted aldol condensation and hydrogenation. This method provides an atom-economical and convenient ...
Powell J - - 2012
The benefits of prophylaxis of haemophilia A patients regarding joint health and quality-of-life are well established. However, adherence to an up to every-other-day infusion regimen is a barrier to widespread adoption of prophylaxis. BAY 79-4980 is an investigational drug consisting of rFVIII-FS (sucrose-formulated recombinant FVIII) reconstituted with liposome solvent. Previous ...
Langhals Heinz - - 2012
Perylenedicarboximides were interlinked in their free peri-position to form dyads where the UV/Vis absorptivity was amplified by exciton effects and the strong fluorescence bathochromically shifted by molecular dynamics. Applications of this type of dye with such increased Stokes' shifts were discussed.
Sánchez-Canel Juan J - - 2012
Background: Hemodialysis systems are potentially thrombogenic, so it is routinely used anticoagulation. Its prescription is with risks though which the recommendations regarding the scheduled dose are still based on very different criteria. Methods: We performed a randomized, crossover pilot study. Six patients underwent six sessions of post-dilution hemodiafiltration with polysulfone ...
Wang Xinsheng - - 2012
A reversed-phase high-performance liquid chromatographic method was developed for the simultaneous quantification of seven phenolic compounds from Rhizoma Sparganii. The samples were separated on a Waters SunFire C18 column with a temperature of 30°C. Gradient elution was applied, using 0.8% acetic acid (solvent A) and methanol (solvent B) with a ...
Shimauchi T - - 2012
The majority of mycosis fungoides (MF) and Sézary syndrome (SS), representatives of cutaneous T-cell lymphoma (CTCL), are positive for CD4, and CD8(+) cases are rare.(1) Here, we established a CD8(+) CD56(+) skin-infiltrating tumour cell line from skin blisters of a patient with CD8(+) SS. Using this cell line, the peculiar ...
Song Gui-Rong - - 2012
Background: The physical development of children and adolescents always attracts widespread attention in society. Aim: The goal of the present study was to systematically analyse the dynamic changes in some anthropometric characteristics among primary school age children. Subjects and methods: Using a longitudinal study design, this study monitored physical growth ...
Löf Christoffer - - 2012
Transient receptor potential (TRP) cation channels are widely expressed and function in many physiologically important processes. Perturbations in the expression or mutations of the channels have implications for diseases. Many thyroid disorders, as excessive growth or disturbed thyroid hormone production, can be a result of dysregulated TSH signaling. In the ...
Ammar M - - 2012
Background:  Psoriasis is a relapsing chronic inflammatory skin disease affecting all populations groups with a peak prevalence of 3% in northern European and Scandinavian Caucasians. Epidemiologic studies have implicated a genetic component to psoriasis. In the last 12 years multiple genome-wide linkage analyses have identified putative susceptibility loci on several ...
Patel Devika - - 2012
  A young infant with fever and oral ulcerations is presented herein. Extensive infectious, nutritional, immunodeficiency and autoimmune work up was performed. Pertinent maternal history suggested the potential diagnosis of neonatal Behçet's, and treatment for this condition resulted in rapid and sustained clinical improvement.
Spyroglou Ariadni - - 2012
Arterial hypertension represents one of the most common diseases in developed countries and the renin-angiotensin-aldosterone system is among the major factors in the regulation of blood pressure and sodium balance. With exception of rare monogenetic diseases, however, inheritance of aldosterone secretion is widely unknown. In this study we investigated the ...
Chammout Ghazi Khalil - - 2012
BACKGROUND: Clinical trials with short and intermediate-term follow-up have demonstrated superior results for total hip replacement as compared with internal fixation with regard to hip function and the need for secondary surgery in elderly patients with a displaced intracapsular femoral neck fracture. The aim of the present study was to ...
Northrup Joseph M - - 2012
Global demand for energy is projected to increase by 40% in the next 20 years, and largely will be met with alternative and unconventional sources. Development of these resources causes novel disturbances that strongly impact terrestrial ecosystems and wildlife. To effectively position ecologists to address this prevalent conservation challenge, we reviewed ...
Mahon A R - - 2012
Early detection of invasive species is critical for effective biocontrol to mitigate potential ecological and economic damage. Laser transmission spectroscopy (LTS) is a powerful solution offering real-time, DNA-based species detection in the field. LTS can measure the size, shape and number of nanoparticles in a solution and was used here ...
Yokobori Takehiko - - 2012
The association of microRNAs (miRs) with cancer progression has been established in many cancers including esophageal squamous cell carcinoma (ESCC). A public microarray database showed that the expression of miR-150 was lower in ESCC than in normal esophageal mucosa. Here, we focused on ZEB1, epithelial-mesenchymal-transition (EMT)-inducers, as target genes of ...
Currie Stuart - - 2012
Proton magnetic resonance (MR) spectroscopy of the brain is a non-invasive, in vivo technique that allows investigation into regional chemical environments. Its complementary use with MR imaging sequences provides valuable insights into brain tumour characteristics, progression and response to treatment. Additionally, its sensitivity to brain dysfunction in the presence of ...
De Lorenzo Andrea - - 2012
Background: Despite the association between HIV and coronary artery disease (CAD), there are no specific recommendations for the cardiovascular evaluation of the HIV-infected population. Besides being a tool for the evaluation of CAD, the exercise treadmill test (ETT) provides insights into functional capacity and autonomic function, which have been frequently ...
Reinbold Catherine - - 2012
In addition to being essential for translation of eukaryotic mRNA, translation initiation factors are also key components of plant-virus interactions. In order to address the involvement of these factors in the infectious cycle of poleroviruses (aphid-transmitted, phloem-limited viruses), the accumulation of three poleroviruses was followed in Arabidopsis thaliana mutant lines ...
Patócs Barbara - - 2012
AIMS: The localisation of the translocation breakpoint of the Ewing sarcoma family of tumours shows significant variability on relatively large regions of fusion partner genes. As a consequence, many alternative forms of EWSR1-ETS translocation exist which make the RNA-based molecular diagnostics of Ewing sarcoma family of tumours complicated. In addition ...
Cavanillas Santiago - - 2012
The complexation processes of Cu(ii) by the phytohormone and the possible antitumoral agent 6-benzylaminopurine (BAP) were studied by Differential Pulse Polarography (DPP) and ultraviolet-visible spectroscopy (UV-vis) in combination with chemometric programs such as Multivariate Curve Resolution by Alternating Least-Squares (MCR-ALS) and Gaussian Peak Adjustment (GPA). All data confirm the formation ...
Grapsa J - - 2012
We describe the case report of an 86-year-old Afro-Caribbean parkinsonian gentleman with intermittent Mobitz II heart block and syncope who received a DDD pacemaker. Due to Parkinson's syndrome, the patient rotated the atrial lead around the pacemaker, causing the famous "Twiddler's syndrome", a rare clinical issue which can easily be ...
Pavlidis Pavlos - - 2012
The aim of the study was to investigate age-related changes in electrogustometry (EGM) thresholds, in morphology and density of the fungiform papillae (fPap) and in vessels' shape and density at the tip of the human tongue.In 156 nonsmokers (74 males, 82 females; age range: 10-80 years), divided in age groups, ...
Benjamin Sophie L - - 2012
While most high and medium oxidation state (O.S. ≥ 3) metal and non-metal fluorides and oxide fluorides are strong Lewis acids, exploration of their coordination chemistry with neutral ligands has been limited and mostly non-systematic. This is despite the very different properties conferred on the acceptor centre by the small ...
Healy Robert Michael - - 2012
The chemical composition of secondary organic aerosol (SOA) formed from the photolysis of 1-nitronaphthalene in a series of simulation chamber experiments has been investigated using an Aerosol Time-of-Flight Mass Spectrometer (ATOFMS). The resulting SOA is characterised by the presence of a dimer (286 Da) proposed to be formed through the ...
Morán-Ramos Sofía - - 2012
Nonalcoholic fatty liver disease (NAFLD) is associated with multiple factors such as obesity, insulin resistance, and oxidative stress. Nopal, a cactus plant widely consumed in the Mexican diet, is considered a functional food because of its antioxidant activity and ability to improve biomarkers of metabolic syndrome. The aim of this ...
Petersen Lyle R - - 2012
Disturbingly unpredictable, disagreeable, and difficult to control - West Nile virus, first identified in the United States in 1999, has entered adolescence. In this year's tally, 3142 cases of West Nile virus disease in humans in 45 states had been reported to the Centers for Disease Control and Prevention as ...
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