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Results 201 - 250 of 3031
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Chandarana Hersh - - 2012
The purpose of this study was to assess the effect of hepatic iron deposition on apparent diffusion coefficient (ADC) values measured with single-shot echo-planar imaging (EPI) diffusion-weighted MRI (DWI) in patients with liver cirrhosis and in vitro. Fifty-two patients with liver cirrhosis who underwent breath-hold single-shot EPI DWI at 1.5 ...
de Jong Pim A - - 2012
The purpose of this study is to establish the difference in lung nodule volume between standard-dose contrast-enhanced and low-dose unenhanced CT. Twenty patients with known pulmonary metastases underwent three CT examinations on 1 day: two unenhanced low-dose (120 kVp and 30 mAs) and a standard-dose (120-140 kVp and 75-200 mAs) ...
Garchar Kim - - 2012
In this essay, I provide a description of the discipline of ethics using the philosophies of Aristotle and the American pragmatist John Dewey. Specifically, I argue that ethics is an active undertaking that is ambiguous and pluralistic. I then normatively prescribe the way in which clinical ethicists ought to approach ...
Zhu Ying - - 2012
Intraductal papilloma of the breast can resemble invasive ductal carcinoma (IDC). The purpose of this study was to characterize MRI features of solitary intraductal papillomas and identify features that differentiate intraductal papillomas from small IDCs. Forty-four intraductal papillomas and 49 small (diameter ≤ 2.0 cm) IDCs confirmed by histopathology were ...
Dennis Ashley - - 2012
Background:  Effective communication with patients is a vital ability for a doctor, and therefore training in communication skills forms an important component of the undergraduate medical curriculum. However, some medical undergraduates experience anxiety in communicating with patients and this makes it difficult for them to communicate with patients effectively. We ...
Meij Pauline - - 2012
To treat patients with refractory cytomegalovirus (CMV) reactivation after allogeneic stem cell transplantation, a phase I/II clinical study on adoptive transfer of in vitro-generated donor-derived or patient-derived CMV pp65-specific CD8 T-cell lines was performed. Peripheral blood mononuclear cells from CMV seropositive donors or patients were stimulated with HLA-A*0201-restricted and/or HLA-B*0702-restricted ...
Khan I - - 2012
Confocal microscopy, a technique that has been extensively applied in cellular biological studies, may also be applied to the visualization and three-dimensional imaging of protein crystals at high resolution on synchrotron beamlines. Protein crystal samples are examined using a commercially available confocal microscope adapted for cryogenic use. A preliminary test ...
Al-Qubati Yasin - - 2012
Leishmaniasis is a widespread parasitic disease seen most often in children and young adults, although it may occur at any age. In Yemen, up until now, specific treatment for cutaneous leishmaniasis (CL) has been challenging. Available chemotherapy is expensive and replete with significant side effects. Standard cryosurgery with liquid nitrogen ...
Stirling Kevin - - 2012
Background:  A small percentage of medical trainees will have performance concerns identified within their clinical practice. These trainees require specific interventions to address these concerns. The Postgraduate Ward Simulation Exercise (PgWSE) was developed as a joint collaboration between the University of Dundee and NHS Education for Scotland (NES). Context:  The ...
Mansell Alexandra - - 2012
Background:  The importance of the post-take ward round to both patient safety and medical education cannot be overemphasised. Despite this, significant variation exists between consultants and senior doctors in the conduct and content of ward rounds. This discrepancy prompted the idea of using a checklist to audit whether essential components ...
Behm Claudia - - 2012
In addition to dietary mycotoxin intake, exposure by inhalation is possible and may result in local effects in the lung. As a first approach to assess the potential local impact of inhaled mycotoxins, the cytotoxicity of 14 different mycotoxins was determined in V79 cell cultures, which served as an in ...
Twomey Mary - - 2012
The practice of offering choice to those women with breast cancer for whom either breast conserving surgery or mastectomy would be equally beneficial has come to be seen as an important aspect of medical care. As well as improving satisfaction with treatment, this is seen as satisfying the ethical principle ...
Gastrich Mary Downes - - 2012
: To assess the relationship between preeclampsia or eclampsia and stroke, myocardial infarction (MI), subsequent cardiovascular outcomes, and long-term survival. : Using the Myocardial Infarction Data Acquisition System in New Jersey (1994-2009), we analyzed cardiovascular outcomes in women with and without preeclampsia or eclampsia and a first MI or stroke ...
Kitchen Mark - - 2012
Background:  A portfolio is a collection of evidence supporting an individual's achievement of competencies and learning outcomes. The material included in the portfolio must be reflected upon, as reflection provides the evidence that learning has taken place. Context:  Portfolio learning is important for two principal reasons: assessment of the trainee, ...
Andersen Holly - - 2012
Even though the evidence-based medicine (EBM) movement labels mechanisms a low quality form of evidence, consideration of the mechanisms on which medicine relies, and the distinct roles that mechanisms might play in clinical practice, offers a number of insights into EBM itself. In this paper, I examine the connections between ...
Bavinck Maarten - - 2012
Shrimp trawling represents an important fishing métier in South India, generating high levels of employment and economic value. It is also a contested métier, ostensibly contributing to environmental degradation and social inequality. This paper investigates the job satisfaction of crew members (captains and workers) on board the shrimp trawlers of ...
Shinmoto Hiroshi - - 2012
The purpose of this study is to investigate whether the intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters are different between prostate cancer, benign prostatic hyperplasia (BPH), and healthy peripheral zone (PZ). Detailed diffusion measurements of 26 patients with histologically proven prostate cancer have been made in this retrospective study. ...
Grimes David A - - 2012
: Screening for inherited thrombophilias with laboratory tests is impractical before starting women on combined oral contraceptives. As an alternative, some recommend eliciting a family history of venous thromboembolism. The validity of this approach, however, remains unclear. : We sought all published reports that correlated a family history of venous ...
Helmons Pieter J - - 2012
Purpose The effects of a direct refill program for automated dispensing cabinets (ADCs) on medication-refill errors were studied. Methods This study was conducted in designated acute care areas of a 386-bed academic medical center. A wholesaler-to-ADC direct refill program, consisting of prepackaged delivery of medications and bar-code-assisted ADC refilling, was ...
Lindahl Cecilia - - 2012
ABSTRACT Animal-related injuries are among the most common occupational injuries in agriculture. Despite the large number of documented animal-related injuries in dairy farming, the issue has received relatively limited attention in the scientific literature. The farmers' own perspectives and views on risks and safety during livestock handling and what they ...
Patel Sameer J - - 2012
: To describe health care providers' missed opportunities for preventing and treating congenital syphilis in New York City. : Review of congenital syphilis cases reported to the New York City Department of Health and Mental Hygiene from January 1, 2000 to December 31, 2009. Receipt and timing of prenatal care, ...
Parle James - - 2012
Background:  Clinical teaching associates (CTAs) are human simulators who use themselves (i.e. their bodies and psyches) as an integral part of the teaching and assessing process. Increasingly, various CTAs are used in clinical education, for instance as stand-ins for clinical tutors or for high-stakes assessments. Context:  Four groups of people ...
Hayter Catherine L - - 2012
The objective of our study was to compare the frequency of osseous and soft-tissue abnormalities in patients presenting with hip pain after resurfacing arthroplasty and after total hip arthroplasty (THA), correlate the MRI findings with histologic results, and determine which MRI findings are predictive of aseptic lymphocytic vasculitis-associated lesions. The ...
Rosenlund H - - 2012
Antioxidant intake may reduce the risk of allergic disease by protecting against oxidative tissue damage. Major sources of antioxidants in the Western world are fruits, vegetables (vitamin C, β-carotene, α-tocopherol), meat and milk (selenium, magnesium, zinc). Children may exclude or eat less of some fruits and vegetables due to cross-reactivity ...
Röschmann K I L - - 2012
Seasonal allergic rhinitis (AR) is a global health problem and its prevalence has increased considerably in the last decades. As the allergic response with its clinical manifestations is triggered by only a few proteins within natural extracts, there is an increasing tendency for single-component-resolved diagnosis and immunotherapy. As natural exposure ...
Williamson James - - 2012
Background:  Out-patient clinics offer trainees one of the most varied clinical experiences within the hospital setting, but they are often chaotic and over-stretched, with limited time for teaching. An awareness of how to improve this learning environment by both trainers and trainees may enhance learning opportunities. Context:  Clinical supervisors need ...
Han Miran - - 2012
The purpose of this study was to compare adjacent vessel sign, increased ipsilateral whole-breast vascularity, and various MRI features as described in the American College of Radiology BI-RADS MRI lexicon with histopathologic predictors in patients with unilateral breast cancer. We retrospectively evaluated breast MRI examinations of 249 patients with histologically ...
Föllmann Wolfram - - 2012
N-Acetyltransferases (NAT) are important enzymes in the metabolism of certain carcinogenic arylamines, as N-acetylation decreases or prevents their bioactivation via N-hydroxylation. To study such processes in the bladder, cell culture models may be used, but metabolic competence needs to be characterized. This study focused on the N-acetylation capacity of two ...
Son Cheol-Hun - - 2012
Recently, chemotherapy and radiotherapy are known to directly affect some immunosuppressive barriers within a tumor microenviroment. We used cyclophosphamide (CTX), which is known to enhance the immune response by suppressing CD4CD25 regulatory T cells (Treg cells) when used at a low dose, as a chemotherapeutic agent to provide a synergic ...
Magay Elena - - 2012
The effect of coupling the salt concentration gradient crystallization method with the use of the paramagnetic salt MnCl(2) and a magnetic field is reported. The use of a simple magnetic device is proposed to have a significant effect on hen egg-white lysozyme crystal growth. Large single crystals greater than 10 mm(3) ...
Roudsari Bahman - - 2012
The purpose of our study was to evaluate the burden of alcohol-related injuries on a radiology department at a level 1 trauma center. We linked the trauma registry (2005-2009) of Harborview Medical Center to billing department data and extracted patient demographic and injury-related characteristics and the radiology services provided. Multivariate ...
Lake Jason P - - 2012
ABSTRACT: Lake, JP, Carden, PJC, and Shorter, KA. Wearing knee wraps affects mechanical output and performance characteristics of back squat exercise. J Strength Cond Res 26(10): 2844-2849, 2012-The aim of this study was to investigate the effects of wearing knee wraps on mechanical output and performance characteristics of back squat ...
Ohno Yoshiharu - - 2012
The purpose of our study was to prospectively and directly compare capability of O(2)-enhanced MRI, MDCT, and perfusion SPECT/CT to clinical outcome measurements in candidates for lung volume reduction surgery (LVRS). Twenty-five consecutive candidates for LVRS (20 men and five women; age range, 45-76 years) underwent MDCT, O(2)-enhanced MRI, and ...
Kandolf-Sekulović Lidija - - 2012
Background  Melanoma in South-East Europe shows varying incidence from 1.7 per 100,000 in Albania to 14.5 per 100,000 in Slovenia, but more detailed data from this region are scarce. In this study, we report epidemiological and clinicopathological characteristics of melanoma in central Serbia. Materials and methods  Epidemiological data were retrieved ...
Hansen Michele - - 2012
: To estimate the prevalence of major birth defects diagnosed by 6 years of age in all births and terminations of pregnancy for fetal anomaly conceived by assisted reproductive technology (when this included intracytoplasmic sperm injection and in vitro fertilization [IVF]) and the remainder of nonassisted reproductive technology-conceived children born ...
Ferguson Emma C - - 2012
The interstitial pneumonias are a group of heterogeneous nonneoplastic lung diseases that may be idiopathic or associated with an underlying abnormality. Although they share some features in common, they also exhibit diverse pulmonary manifestations. Imaging plays an essential role in characterizing this group of disorders and can often suggest the ...
Patel Uday B - - 2012
The Magnetic Resonance Imaging and Rectal Cancer European Equivalence (MERCURY) Study validated the use of MRI for posttreatment staging and its correlation with survival outcomes. As a consequence, reassessment of MRI scans after preoperative therapy has implications for surgical planning, the timing of surgery, sphincter preservation, deferral of surgery for ...
Patel Amish - - 2012
The purpose of this review is to describe the clinical factors related to balloon-occluded retrograde transvenous obliteration, including the preparation needed, the technique and challenges, and the outcomes. Although the procedure can be performed when transjugular intrahepatic portosystemic shunt is contraindicated or when endoscopic management fails, balloon-occluded retrograde transvenous obliteration ...
Ha Alice S - - 2012
The purpose of this article is to provide a review of the indications for shoulder arthroplasty, describe preoperative imaging assessment, present new and modified designs of shoulder arthroplasty, illustrate normal and abnormal postoperative imaging findings, and review key radiographic measurements. Knowledge of the physiologic purpose, orthopedic trends, imaging findings, and ...
Martin Louis G - - 2012
Many patients with cirrhotic effusions in the peritoneal and pleural spaces lead a difficult existence. In addition to their decreased mobility and physical discomfort, they spend hours in the hospital or an outpatient facility undergoing peritoneal and pleural drainage. Liver transplantation is the ultimate solution for those with cirrhotic effusions ...
Curatolo Andrea - - 2012
The purpose of this study was to evaluate a new imaging technique for the assessment of breast cancer tumor margins. The technique entails deployment of a high-resolution optical imaging needle under ultrasound guidance. Assessment was performed on fresh ex vivo tissue samples. Use of the ultrasound-guided optical needle probe allowed ...
Bomers Joyce G R - - 2012
The purpose of this article is to evaluate MRI-guided therapies and to investigate their feasibility for focal therapy in prostate cancer patients. Relevant articles were retrieved using the PubMed online search engine. Currently, MRI-guided laser ablation and MRI-guided focused ultrasound are the most promising options for focal treatment of the ...
Darcy Michael - - 2012
The purpose of this article is to describe the evaluation of transjugular intrahepatic portosystemic shunts (TIPS) and the management of dysfunctional shunts. TIPS can become dysfunctional if stenosis develops in the shunt or the hepatic vein above the shunt. Screening allows detection of stenoses before portal hypertensive-related complications recur. Revision ...
Ferral Hector - - 2012
Budd-Chiari syndrome (BCS) is an uncommon condition characterized by obstruction of the hepatic venous outflow tract. Presentation may vary from a completely asymptomatic condition to fulminant liver failure. BCS is an example of postsinusoidal portal hypertension. The management can be divided into three main categories: medical, surgical, and endovascular. The ...
Fidelman Nicholas - - 2012
The purpose of this article is to review the indications, outcomes, complications, patient selection, and technical aspects of creating a transjugular intrahepatic portosystemic shunt (TIPS). The best available evidence supports the use of TIPS in secondary prevention of variceal bleeding and in refractory ascites, although TIPS is also commonly used ...
Petscavage Jonelle M - - 2012
The purpose of this article is to provide a review of indications for shoulder arthroplasty, describe preoperative imaging assessment, present new and modified designs of shoulder arthroplasty, illustrate normal and abnormal postoperative imaging findings, and review key radiographic measurements. Knowledge of the physiologic purpose, orthopedic trends, imaging findings, and complications ...
Duigenan Shauna - - 2012
The goal of this review is to examine the current imaging literature and develop basic imaging guidelines for evaluation of children with inflammatory bowel disease (IBD). The three following typical clinical scenarios in the imaging evaluation of IBD are considered: patient with an initial diagnosis of suspected IBD, the goals ...
Chung Woo-Suk - - 2012
Our retrospective study compared Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 with modified CT criteria to determine their respective utilities as a prognostic indicator. Using both sets of criteria, we compared treatment responses of patients with colorectal liver metastases treated with bevacizumab-containing chemotherapy with those of patients treated ...
Church M K - - 2012
Urticaria, and especially chronic spontaneous urticaria (CSU), is a difficult condition to treat. Consequently, clinicians need to use the best H(1)-antihistamines currently available and the pharmaceutical industries need to keep developing H(1)-antihistamines that are more effective than the ones we have today. To do this we need to be able ...
Davis Marcherie - - 2012
Baseline levels of innate and adaptive immune cell functions were studied in patients with pancreatic cancer. The effects of pemetrexed were measured at 7 and 14 days after initial therapy then 14 days after combination therapy with gemcitabine. Pretherapy levels of absolute numbers of natural killer (NK) cells positively correlated ...
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