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Results 451 - 500 of 2739
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Singh Reetu R - - 2012
1. Glucocorticoids are necessary for fetal development but clinical and experimental studies suggest excess exposure may be detrimental to health in the short and in the longer term. 2. Exposure of the fetus to synthetic glucocorticoids can occur if the mother has a medical condition requiring glucocorticoid therapy (such as ...
Hirabayashi K - - 2012
BACKGROUND: There have been no reports of human herpesvirus-6 (HHV-6) encephalitis treatment based on both HHV-6 DNA load and the antiviral agent's concentration in the cerebrospinal fluid (CSF). PATIENT: A 20-year-old male with a hematological malignancy developed HHV-6 encephalitis 15 days after unrelated cord blood transplantation (UCBT). He had fever, ...
Dalenbäck J - - 2012
PURPOSE: The purpose of this study was to establish long-term outcome after elective adult umbilical hernia (AUH) repair. METHODS: Peri- and postoperative data considering all consecutive procedures at our institution during the time span from 1999 to 2009 were retrospectively gathered and followed by a questionnaire and, if needed, a ...
Roldan-Martin Maria B - - 2012
An 11-year-old Caucasian male with history of abdominal pain, diarrhoea, fatigue, emesis and fever on the previous days presented with dehydratation, shock and acute mesenteric ischaemia. Final diagnosis of Addison's disease was made.
Devi P - - 2012
Indians have high rates of cardiovascular disease. Hypertension (HTN) is an important modifiable risk factor. There are no comprehensive reviews or a nationally representative study of the burden, treatments and outcomes of HTN in India. A systematic review was conducted to study the trends in prevalence, risk factors and awareness ...
Kortekaas Kirsten A - - 2012
OBJECTIVE AND DESIGN: The pathophysiology of ischemia/reperfusion (I/R) injury is dominated by an inflammatory response. In the identification of new therapeutic agents, the role of individual cytokines may be essential. Interleukin (IL)-9 is a pleiotropic cytokine recently identified to be involved in various immune responses. In this study, the role ...
Jonaidi H - - 2012
In mammals and birds, neuropeptide Y (NPY) and gamma-aminobutyric acid (GABA) are found in brain areas known to be involved in the control of ingestive behavior and act to increase voluntary food intake. In rats, significant evidence suggest a functional and behavioral interaction between NPY and GABA mediated transmission in ...
Laakso Ilkka - - 2012
In international guidelines, basic restriction limits on the exposure of humans to low-frequency magnetic and electric fields are set with the objective of preventing the generation of phosphenes, visual sensations of flashing light not caused by light. Measured data on magnetophosphenes, i.e. phosphenes caused by a magnetically induced electric field ...
Droz-Perroteau Cécile - - 2012
PURPOSE: Fear of discontinuing concomitant anti-epileptic drugs (AEDs) may lead to potentially unnecessary and perhaps unsafe polypharmacy. The effect of withdrawing concomitant AEDs on epilepsy control was therefore studied in long-term users of levetiracetam. METHODS: The EULEV cohort followed patients initiating levetiracetam in France in 2005 or 2006 for one ...
Belmain Stephen R - - 2012
Tephrosia vogelii has been used for generations as a pest control material in Africa. Recently, two chemotypes have been reported based on the occurrence (chemotype 1) or absence (chemotype 2) of rotenoids. This could have an impact on the efficacy and reliability of this material for pest control. We report ...
Sikorski Alyssa - - 2012
A large number of novel single-stranded DNA (ssDNA) viruses have been characterised from various environmental sources in the last 5 years. The bulk of these have been from faecal sources, and faecal sampling is an ideal non-invasive pathogen sampling method. We characterised a novel ssDNA from a porcine faecal sample from ...
Guo Lei - - 2012
Hepatocellular carcinoma (HCC) is one of the most deadly human cancers because of its high incidence of metastasis. Despite extensive efforts, therapies against metastasis of HCC remain underdeveloped. Vacuole membrane protein 1 (Vmp1) was recently identified to be involved in cancer-relevant processes, however its expression, clinical significances and biological function ...
Burkhardt Jan-Karl - - 2012
PURPOSE: Meningiomas in children are rare, especially those located at the skull base. In this study, we report our experience of meningioma surgery in the pediatric population and compare our findings of skull base (SB) versus non-skull base (NSB) meningiomas. METHODS: From our database of 724 surgically treated meningioma patients ...
Song Yue-Lin - - 2012
Four new flavonol glycosides (1-4), polygalins D-G, together with 12 known flavonoids (5-16) were isolated from the aerial parts of Polygala sibirica L. . The chemical structures of these compounds were characterised by NMR and ESI-MS spectroscopic data and acid hydrolysis results. This report is a continuous research work on ...
Sato Yohei - - 2012
BACKGROUND AND PURPOSE: Cardiopulmonary complications are common after subarachnoid hemorrhage (SAH), and include pulmonary edema (PE). The purpose of this study was to investigate circulatory characteristics of normovolemia and normotension therapy after SAH using pulse contour analysis, and to reveal the mechanisms of PE after SAH. METHODS: Pulse contour analysis ...
Lin Xia - - 2012
Objectives: The aim of this study was to perform a systematic preclinical evaluation of norcantharidin (NCTD)-loaded intravenous lipid microspheres (NLM). Research design and methods: Pharmacokinetics, biodistribution, antitumor efficacy and drug safety assessment (including acute toxicity, subchronic toxicity, hemolysis testing, intravenous stimulation and injection anaphylaxis) of NLM were carried out in ...
Soudani Nejla - - 2012
Chromium(VI), a very strong oxidant, causes high cytotoxicity through oxidative stress in tissue systems. Our study investigated the potential ability of ethanolic Citrus aurantium L., family Rutaceae extract, used as a nutritional supplement, to alleviate lung oxidative damage induced by Cr(VI). A high-performance liquid chromatography coupled with a mass spectrometer ...
Hong Ji-Youn - - 2012
OBJECTIVES: The objective of this study was to elucidate the socket healing process and biodegradation of incorporating synthetic bone fillers followed by grafting of the fresh extraction socket. MATERIALS AND METHODS: Third premolars in four quadrants of eight beagle dogs were extracted and randomly treated with either one of hydroxyapatite ...
Speksnijder Caroline M - - 2012
BACKGROUND: Neck and shoulder complaints can be a direct result of a neck dissection. METHODS: Maximal active lateral flexion of the neck, forward flexion and abduction of the shoulder, and self-perceived function were determined in 145 patients treated for oral cancer. RESULTS: No short-term influence of radiotherapy was found on ...
Schouten J N L - - 2012
BACKGROUND: Idiopathic noncirrhotic portal hypertension (INCPH) has been reported increasingly in patients with HIV infection. AIM: To evaluate the number of nationwide diagnosed HIV-associated INCPH cases and to assess its clinical features, risk factors and outcome. METHODS: All HIV centres in the Netherlands were contacted and requested to notify INCPH ...
Kume Shinji - - 2012
Autophagy meaning 'self-eating' in Greek, is a large-scale mechanism of intracellular degradation that seeks to maintain homeostasis in cells of all eukaryotes, from yeast to humans. Over the past several decades, autophagy research has actively proceeded both at home and abroad. As a result, studies have reported the physiological role ...
Eichardt Roland - - 2012
The problem of estimating magnetic nanoparticle distributions from magnetorelaxometric measurements is addressed here. The objective of this work was to identify source grid parameters that provide a good condition for the related linear inverse problem. The parameters investigated here were the number of sources, the extension of the source grid, ...
Myers Janet J - - 2012
Abstract The delivery of HIV risk assessment and behavioral counseling by clinicians in HIV clinical settings is one component in a comprehensive "positive prevention" strategy to help patients reduce their transmission risk behavior. Clinicians engage in behavioral prevention inconsistently, however, depending on whether patients are new to a practice or ...
Smith Peter K - - 2012
The transient receptor potential (TRP) superfamily consists of 28 members in mammals (27 in human) that act as polymodal sensors and ion channels. They regulate cellular calcium influx, generate depolarization thereby triggering voltage dependent cellular processes, and in turn they are critical in inducing the metabolic activities of cells. It ...
Marques M - - 2012
BACKGROUND: Few studies focus on cross-cultural differences in Chronic fatigue syndrome (CFS). PURPOSE: This study aimed to (1) compare fatigue severity and impairment, somatic complaints, psychological distress, and quality of life (QoL) in a population of Portuguese and Dutch patients; (2) explore the differential contribution of behavioral and cognitive determinants ...
Zhu Changfu - - 2012
Antioxidants are protective molecules that neutralize reactive oxygen species and prevent oxidative damage to cellular components such as membranes, proteins and nucleic acids, therefore reducing the rate of cell death and hence the effects of ageing and ageing-related diseases. The fortification of food with antioxidants represents an overlap between two ...
Milgrom Peter - - 2012
Objective: High levels of Streptococcus mutans on teeth of young children are predictive of Early Childhood Caries (ECC). Transmission from mother-to-child is common and studies have demonstrated treatment of the mother results in less ECC. The objective of this study was to determine how dentists have adopted the practice of ...
Cataife Guido - - 2012
Abstract This article measures differences in the likelihood of treatment of chronic diseases in elders across types of coverage (private, public and social security) in four major Latin American cities: Buenos Aires (Argentina), Sao Paulo (Brazil), Santiago (Chile) and Montevideo (Uruguay). We used a logistic regression to estimate the odds ...
Scarpa Marco - - 2012
BACKGROUND: Esophageal adenocarcinoma is often associated with obesity, and a 5 Kg m(-2) increase in body mass index (BMI) has, in fact, been found to be strongly associated with the risk of this type of cancer (RR, 1.52; p < 0.0001). Esophagectomy with lymphoadenectomy is the mainstay of therapy for these patients. The aim ...
Lopes Bárbara - - 2012
Background: Research suggested that negative affective-laden sounds act as environmental stressors that elicit negative affect (Bradley and Lang, 2000a). Aims: We tried to test for the role of an interaction between predisposition to hallucinatory experiences and exposure to negative affective laden sounds for the presence of paranoid ideation. Method: We ...
Kabbage Maria - - 2012
This study aims to evaluate αB-crystallin expression in infiltrating ductal breast carcinomas (IDCAs), as well as, its prognostic significance. Using a two-dimensional electrophoresis matrix-assisted laser desorption/ionisation-time of flight mass spectrometry investigation coupled to an immunohistochemical approach, we have assessed the expression of αB-crystallin in IDCAs, as well as, in other ...
Sestak Ivana - - 2012
Trials with tamoxifen have clearly shown that the risk of developing oestrogen receptor-positive breast cancer can be reduced by at least 50 % with prophylactic agents. The current challenge is to find new agents which achieve this or better efficacy, but with fewer side effects. Recent results indicate that the selective ...
Hermanns-Clausen M - - 2012
AIMS: Recently, several synthetic cannabinoids were identified in herbal mixtures consumed as recreational drugs alternatively to Cannabis products. The aim was to characterize the acute toxicity of synthetic cannabinoids as experienced by emergency patients. DESIGN: This was a retrospective study targeting patients seeking emergency treatment after recreational use of synthetic ...
Erzengin Mahmut - - 2012
Human serum paraoxonase 1 (PON1; EC 3.1.8.1) is a high-density lipoprotein associated, calcium-dependent enzyme that hydrolyses aromatic esters, organophosphates and lactones and can protect the low-density lipoprotein against oxidation. In this study, in vitro inhibition effect of some dihydroxy coumarin compounds namely 6,7-dihydroxy-3-(2-methylphenyl)-2H-chromen-2-one (A), 6,7-dihydroxy-3-(3-methylphenyl)-2H-chromen-2-one (B) and 6,7-dihydroxy-3-(4-methylphenyl)-2H-chromen-2-one (C) on ...
Kanakis George - - 2012
OBJECTIVE: The widespread application of abdominal computerized tomography (CT) imaging has revealed that 0.98-4.0% of individuals harbour adrenal lesions (incidentalomas). There is however paucity of information regarding the prevalence of adrenal lesions in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETS). Purpose of this study was to estimate the prevalence of adrenal ...
Ou Phalla - - 2012
Coronary sequelae of Kawasaki disease, post-surgical coronary lesions and cardiac allograft vasculopathy are the main causes of acquired coronary pathology in childhood. Surveillance and timely recognition of coronary problems in children who are at risk of ischemic events are imperative and noninvasive imaging is increasingly utilized for these purposes. Herein, ...
Nadarevic Lena - - 2012
Two theoretical frameworks have been proposed to account for the representation of truth and falsity in human memory: the Cartesian model and the Spinozan model. Both models presume that during information processing a mental representation of the information is stored along with a tag indicating its truth value. However, the ...
Cho Young Sun - - 2012
Transgenic marine medaka (Oryzias dancena) germlines were generated by the microinjection of the red fluorescent protein (RFP) reporter gene (rfp) driven by the endogenous choriogenin H gene (chgH) promoter. The selected transgenic lines contained multiple copies of the transgene (3-42 copies per cell) in their genomes. Although all the founders ...
Kobashi Haruhiko - - 2012
Aim:  Although it is a common complication of sepsis, sepsis-associated liver injury has not been substantially recognized, because its diagnostic criteria and clinical implications are unclear. We aimed to elucidate the incidence, manifestation, disease type classification and prognosis of sepsis-associated liver injury. Methods:  The subjects were 588 patients admitted to ...
Jalili M - - 2012
A simple method for the reduction of aflatoxins B(1) (AFB(1)), B(2) (AFB(2)), G(1) (AFG(1)), G(2) (AFG(2)) and ochratoxin A (OTA) in white pepper was studied. Response surface methodology (RSM) was applied to determine the effect of four variables, which included time (20-60 min), temperature (30-70°C), calcium hydroxide (Ca(OH)(2)) (0-1%) and hydrogen ...
Yamazaki M - - 2012
We report the fabrication of non-emissive short- and long-pass filters on plastic for high sensitivity fluorescence detection. The filters were prepared by overnight immersion of titania-coated polyethylene terephthalate (PET) in an appropriate dye solution - xylene cyanol for short-pass filtering and fluorescein disodium salt for long-pass filtering - followed by ...
Addley J - - 2012
The causes of obstructive jaundice are varied, and timely, accurate methods of investigation are essential to avoid the development of complications. Imaging, invasive or non-invasive, should be carefully selected depending on the suspected underlying pathology in order to determine the degree and level of obstruction along with tissue acquisition and ...
Fasciotti Maíra - - 2012
Corrole and four of its isomers with subtle structural changes promoted by exchange of nitrogen and carbon atoms in the corrole ring have been studied by traveling wave ion mobility mass spectrometry and collision induced dissociation experiments. Significant differences in shapes and charge distributions for their protonated molecules were found ...
Hill Nichola J - - 2012
Studies of pathogen transmission typically overlook that wildlife hosts can include both migrant and resident populations when attempting to model circulation. Through the application of stable isotopes in flight feathers, we estimated the migration strategy of mallards (Anas platyrhynchos) occurring on California wintering grounds. Our study demonstrates that mallards- a ...
Rush Thomas - - 2012
Integration of laboratory training into the Centers for Disease Control and Prevention's (CDC) Field Epidemiology Training Program (FETP) began in 2004 and has advanced the training of laboratory scientists worldwide on the basic principles of epidemiology, disease surveillance, and outbreak investigation. The laboratory component of the FE(L)TP training has traditionally ...
Prokop Pavol - - 2012
Humans (Homo sapiens) are unique primates due to a lack of a thermally insulating fur covering, typical of all other primates. Our primary goal was to examine the "ectoparasite avoidance mediated by mate choice hypothesis" suggesting that women prefer men lacking chest hair in order to avoid ectoparasite loads. We ...
Liu Rui - - 2012
Platinum(ii) diimine complexes with naphthalimide substituted fluorenylacetylide ligands are synthesized and characterized. The complexes exhibit long-lived (3)ILCT or (3)ILCT/(3)MLCT/(3)LLCT excited states (τ = ∼20-30 μs) and broadband triplet transient absorption in the visible-NIR region. Nonlinear transmission experiments at 532 nm demonstrate that these complexes are efficient nonlinear absorbing materials.
Samuels Joshua X - - 2012
Members of the order Carnivora display a broad range of locomotor habits, including cursorial, scansorial, arboreal, semiaquatic, aquatic, and semifossorial species from multiple families. Ecomorphological analyses from osteological measurements have been used successfully in prior studies of carnivorans and rodents to accurately infer the locomotor habits of extinct species. This ...
Hashimoto Takeshi - - 2012
PURPOSE: Preoperative elevation of markers of systemic inflammation is associated with a poor outcome in several cancers. The purpose of this study was to evaluate the prognostic significance of preoperative systemic inflammatory markers in patients with non-metastatic upper urinary tract cancer (UUTC). METHODS: The records of 84 patients with non-metastatic ...
Hong Soon Jun - - 2012
Objectives: To examine the comparative fate of adipose-derived stem cells (ASCs) as well as their impact on coronary microcirculation following either retrograde coronary venous or arterial delivery. Background: Local delivery of ASCs to the heart has been proposed as a practical approach to limiting the extent of myocardial infarction. Mouse ...
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