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Results 301 - 350 of 2194
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de Barros Pellegrinelli K - - 2012
de Barros Pellegrinelli K, de O. Costa LF, Silval KID, Dias VV, Roso MC, Bandeira M, Colom F, Moreno RA. Efficacy of psychoeducation on symptomatic and functional recovery in bipolar disorder. Objective:  To evaluate the efficacy of psychoeducation in the symptomatic and functional recovery, and quality of life (QoL) in ...
Schwab Inessa - - 2012
Intravenous immunoglobulins (IVIgs) efficiently suppress a variety of autoimmune diseases. Over the past few years several potential mechanisms underlying this anti-inflammatory activity have become apparent. Amongst these, terminal sialic acid residues in the sugar moiety of the IgG constant fragment have been shown to be critical for the anti-inflammatory activity ...
Tan Guoqiang - - 2012
Human mitochondrial protein mitoNEET is a novel target of type II diabetes drug pioglitazone, and contains a redox active [2Fe-2S] cluster that is hosted by a unique ligand arrangement of three cysteine and one histidine residues. Here we report that zinc ion can compete for the [2Fe-2S] cluster binding site ...
Inoue Yasuyuki - - 2012
Objectives: The aim of this study was to assess the drug interaction between high doses of micafungin and cyclosporine A (CyA) in allo-HSCT patients. Methods: We assigned 15 patients to Groups 1, 2, or 3. We investigated the serial changes in the blood concentration/dose (C/dose) of intravenous CyA during micafungin ...
Nardi Antonio - - 2012
Blockade of voltage-gated sodium channels (VGSCs) has been used successfully in the clinic to enable control of pathological firing patterns that occur in conditions as diverse as chronic pain, epilepsy, and arrhythmias. Herein we review the state of the art in marketed sodium channel inhibitors, including a brief compendium of ...
Hočevar-Boltežar Irena - - 2012
Objectives:  To compare the prevalence of laryngopharyngeal reflux in choristers, teachers and control subjects without vocal load at work, and to determine the risk factors for laryngopharyngeal reflux. Design:  A prospective, multicentre, multivariate comparative study Participants:  One hundred and nineteen singers from four professional choirs, seventy teachers from four schools, ...
Aas C J - - 2012
On the basis of the fully relativistic screened Korringa-Kohn-Rostoker method we investigate the variation in the magnetocrystalline anisotropy energy (MAE) of hexagonal close-packed cobalt with the addition of platinum impurities. In particular, we perform calculations on a bulk cobalt system in which one of the atomic layers contains a fractional, ...
Liao Chengsong - - 2012
Increasing evidence suggests that root extracellular proteins are involved in interactions between roots and their soil environment. In the present study, exudates released by six-day-old roots of the three legume species white lupin (Lupinus albus), soybean (Glycine max), and cowpea (Vigna sinensis) were collected under axenic conditions, and their constitutively ...
Fiebiger Benjamin M - - 2012
The immediate presentation of peptide epitopes on MHC class I (MHC I) after antigen expression has led to the concept that MHC I ligands are mostly derived from defective ribosomal products (DRiPs), a subset of newly synthesized proteins that are rapidly degraded by the proteasome. Whether and to what extent ...
Li Minmin - - 2012
A new, highly sensitive, and selective method was developed for the determination of the cyflumetofen residue in water, soil, and fruits by using gas chromatography quadruple mass spectrometry. The target compound was extracted using acetonitrile and then cleaned up using dispersive solid-phase extraction with primary and secondary amine and graphitized ...
Yilmaz Hakki - - 2012
A 25-year-old woman with a severe migraine begins to use a migraine specific agent, eletriptan (40 mg/d). One month later, she had oligomenorrhea and galactorrhea. We ruled out all causes of hyperprolactinemia. To our knowledge, this is the first published postmarketing case report of eletriptan- induced hyperprolactinemia, presented as oligomenorrhea ...
Egemen Emrah - - 2012
PURPOSE: Iatrogenic aneurysms are very rare in children. Characteristic clinical manifestations are variable and asymptomatic course is possible especially for fusiform dilatation of internal carotid artery. Even though radiological diagnosis is easy, the management of iatrogenic intracranial aneurysm is still a subject for discussion. METHODS: Fusiform dilatations of internal carotid ...
Walker V A - - 2012
A recent epidemiological study indicated that various factors may be related to injury in dressage horses, but the mechanism by which these injuries occur has yet to be determined. The suspensory ligament (SL) is a frequent site of injury, and it is assumed that greatest strain is placed on this ...
Lee Song-Tay - - 2012
Prostate cancer has been known to be the second highest cause of death in cancer among men. Pomegranate is rich in polyphenols with the potent antioxidant activity and inhibits cell proliferation, invasion and promotes apoptosis in various cancer cells. This study demonstrated that pomegranate fruit juice could effectively hinder the ...
Hara Yoshiaki - - 2012
Patent ductus venosus (PDV) is a rare condition of a congenital portosystemic shunt from the umbilical vein to the inferior vena cava. This report presents the case of an adult patient with PDV, who was successfully treated with laparoscopic shunt division. A 69-year-old male was referred with hepatic encephalopathy. Contrast-enhanced ...
Allamani Allaman - - 2012
Alcohol-related policies and the prevention of alcohol use-related problems, as well as their creation, are accomplished through planned interventions- laws, social and health programs, community-based initiatives-as well as through complex social movements and efforts implemented by the communities. Among both citizens and alcohol use intervention experts, the following three human ...
Chen Da - - 2012
When paired with high-powered chemometric analysis, spectrometric methods offer great promise for the high-throughput analysis of complex systems. Effective classification or quantification often relies on signal preprocessing to reduce spectral interference and optimize the apparent performance of a calibration model. However, less frequently addressed by systematic research is the affect ...
Briani C - - 2012
BACKGROUND AND PURPOSE: Chemotherapy-induced peripheral neuropathy is a major adverse effect of Oxaliplatin (OXL) treatment. Whereas neurophysiologic study is commonly used to assess the occurrence and severity of polyneuropathies, ultrasound (US) analysis of the peripheral nerves, an emerging technique in the study of peripheral nerve diseases, has never been used ...
Tozzi Alberto E - - 2012
Tozzi AE, Mazzotti E, Di Ciommo VM, Dello Strologo L, Cuttini M. Quality of life in a cohort of patients diagnosed with renal failure in childhood and who received renal transplant. Abstract:  Studies on HRQOL on kidney-transplanted young adults who had a diagnosis of chronic renal failure (CRF) in the ...
Moshaverinia Alireza - - 2012
The objectives of this study were to: (1) develop an injectable and biodegradable scaffold based on oxidized alginate microbeads encapsulating periodontal ligament (PDLSCs) and gingival mesenchymal stem cells (GMSCs); and (2) investigate the stem cell viability, and osteogenic differentiation of the stem cells in vitro. Stem cells were encapsulated using ...
Bekaert Michaël - - 2012
Here, we describe our updated mathematical model of Arabidopsis thaliana Columbia metabolism, which adds the glucosinolates, an important group of secondary metabolites, to the reactions of primary metabolism. In so doing, we also describe the evolutionary origins of the enzymes involved in glucosinolate synthesis. We use this model to address ...
Murao Kazutoshi - - 2012
Although a wide range of treatments have been used in the treatment of palmoplantar pustulosis (PPP), PPP is still very difficult to treat. We report a patient who had a dramatic reduction in PPP lesions after bypass surgery for Leriche syndrome. We assume that improved blood circulation had a crucial ...
Liu Lichen - - 2012
In this work, ultra-small Cu(2)O nanoparticles have been loaded on TiO(2) nanosheets with {001} facets exposed through a one-pot hydrothermal reaction. These Cu(2)O nanoparticles are well-dispersed on TiO(2) nanosheets with narrow size distributions and controllable sizes from 1.5 to 3.0 nm. Through XRD, TEM, N(2) absorption-desorption isotherms and UV-vis diffuse ...
Akiyama Yoshitake - - 2012
Insect dorsal vessel (DV) tissue seems well suited for microactuators due to its environmental robustness and low maintenance. We describe an insect muscle-powered autonomous microrobot (iPAM) and its acceleration with a neuroactive chemical, crustacean cardioactive peptide (CCAP). The iPAM, consisting of a DV tissue and a frame, was designed on ...
Chevillon Christine - - 2012
The southern cattle tick, Rhipicephalus microplus, is the ixodid species causing the largest economic losses in tropical agrosystems because of its recurrent invasive success, explosive demography on bovine herds, vector competence for diverse pathogens and frequent development of acaricide resistance. Its ecology and the physiological bases of the acaricide resistances ...
Zhang Honghong - - 2012
Pannexins form membrane channels that release biological signals to communicate with neighboring cells. Here, we report expression patterns of pannexin 1 (Panx1) and pannexin 2 (Panx2) in the olfactory epithelium and olfactory bulb of adult mice. In situ hybridization revealed that mRNAs for Panx1 and Panx2 were both expressed in ...
Costa R A - - 2012
This long-term study (2003-2010) compared the breeding parameters of great tits living in a paper-and-pulp-industry area to those of great tits living in a rural area on the west coast of Portugal. We also measured the abundance of caterpillar biomass, an important food source and determinant of breeding success for ...
Peche Vivek S - - 2012
Cyclase-associated proteins are highly conserved proteins that have a role in the regulation of actin dynamics. Higher eukaryotes have two isoforms, CAP1 and CAP2. To study the in vivo function of CAP2, we generated mice in which the CAP2 gene was inactivated by a gene-trap approach. Mutant mice showed a ...
Pelisek Jaroslav - - 2012
Stroke is among the major causes of mortality and disabilities in the world. About 80 % of all strokes in the anterior circulation are ischemic and up to 20 % of all ischemic strokes are caused by extracranial atherosclerotic carotid artery stenosis. The prevalence of a cervical internal carotid artery stenosis increases ...
Molinares Beatriz - - 2012
Molinares B, Álvarez S, García V, Sepúlveda ME, Yepes NL, Peláez S. Extrahepatic portal vein aneurysm after liver transplantation in a child: Case report. Abstract:  Portal vein aneurysms are very rare and represent <3% of all venous aneurysms. They can be congenital or acquired. Most patients do not have liver ...
Cardoso Marcelo M - - 2012
We explored whether the modulation of microglia activation with minocycline is beneficial to the therapeutic actions of bone marrow mononuclear cells (BMMCs) transplanted after experimental stroke. Male Wistar adult rats were divided in four experimental groups: ischemic control saline treated (G1, N = 6), ischemic minocycline treated (G2, N = 5), ischemic BMMC treated ...
Schunck Reinhard - - 2012
OBJECTIVES: This study analyses the effects of different unemployment durations on smoking behaviour in Germany by investigating smoking take-up, relapse, quitting and smoking intensity. METHODS: Longitudinal data from the German Socio-Economic Panel from the years 1998, 2001, 2002, 2004, 2006, and 2008 were used to examine the effect of unemployment ...
Jing Lijuan - - 2012
A simple, sensitive, and rapid method for determination of L-trantinterol in rat plasma was developed for the first time by using LC coupled to MS/MS based on chiral stationary phase. A baseline separation of the enantiomers of trantinterol was achieved on a Chirobiotic V column, using a mixture of acetonitrile-methanol-ammonia-acetic ...
Perumal Karthikeyan - - 2012
The synthesis, photophysical, and electrochemical attributes of a novel class of boron difluorides containing an aromatic-fused alicyclic/hetero-alicyclic ring built on a β-iminoenamine chromophoric backbone are reported. The compounds displayed large Stokes shifts (86-121 nm), and were emissive in the solid state. The quantum yields obtained in solution at room temperature were ...
Rokholm B - - 2012
OBJECTIVES:Twin and adoption studies suggest that family environment has little, if any, influence on body mass index (BMI) in adulthood. We investigated the hypothesis that the differences in the years of birth between siblings influence their similarity in BMI at comparable ages, which would give evidence for a possibly modifiable ...
Xiang Yan - - 2012
As one of the most effective synthesis tools, layer-by-layer (LbL) self-assembly technology can provide a strong non-covalent integration and accurate assembly between homo- or hetero-phase compounds or oppositely charged polyelectrolytes, resulting in highly-ordered nanoscale structures or patterns with excellent functionalities and activities. It has been widely used in the developments ...
Zdragas A - - 2012
Aims:  To detect the prevalence, the seasonal occurrence and distribution of Salmonella serotypes in poultry products and to determine the resistance profile of Salmonella isolates. Method and Results:  A total of 96 skin-on chicken carcasses and 30 liver samples were analysed between May 2007 and May 2009 from twenty-two different ...
Tan Fei - - 2012
To improve cell attachment and to understand the effects of positive charge on the behavior of osteoblasts, 2-(methacryloyloxy)ethyl-trimethylammonium chloride (MAETAC), a positively charged monomer, was incorporated into poly(ethylene glycol)-diacrylate (PEGDA) hydrogel. The physicochemical properties of the resultant polymers, including the degree of acrylation of PEGDA, pKa of MAETAC, swelling ratio, ...
Soler Laia - - 2012
This study aims to provide evidence concerning the effects of experiencing multiple forms of victimization (poly-victimization) on self-esteem and post-traumatic stress symptoms in Spanish adolescents. A total of 722 adolescents were recruited from seven secondary schools in Catalonia, Spain. The Rosenberg Self-Esteem Scale, the Youth Self Report and the Juvenile ...
Davoll Sabine - - 2012
OBJECTIVES: The purpose of this study was to analyse the extent to which breast cancer patients excuse inconveniences that occur during their hospitalisation, and how this "tendency to excuse" affects their satisfaction with the hospital stay. METHODS: Breast cancer patients undergoing treatment at one of 51 breast centres in North ...
O'Keeffe M - - 2012
Humans have an innate requirement for sleep that is intrinsically governed by circadian and endocrine systems. More recently, reduced sleep duration has gained significant attention for its possible contribution to metabolic dysfunction. Significant evidence suggests that reduced sleep duration may elevate the risk for impaired glucose functioning, insulin resistance and ...
Rahmioglu Nilufer - - 2012
Atypical cytochrome P450 3A4 (CYP3A4) enzyme activity-induced and inhibited-is thought to be the driver of numerous poor or adverse therapeutic responses to up to 50 % of all commonly prescribed drugs. We carried out a genome-wide association study to identify common genetic variants associated with variation in induced CYP3A4 activity. A ...
Zhu Yikang - - 2012
The characteristics of the cognitive processing of food, body and emotional information in patients with anorexia nervosa (AN) are debatable. We reviewed functional magnetic resonance imaging studies to assess whether there were consistent neural basis and networks in the studies to date. Searching PubMed, Ovid, Web of Science, The Cochrane ...
Hori Nobuhide - - 2012
PURPOSE: To determine whether significant correlations existed between the morphological and functional parameters of the macular region of eyes with open-angle glaucoma (OAG). METHODS: Forty eyes of 40 OAG patients were studied. The morphological parameters were obtained by optical coherence tomography (OCT), and the functional parameters were acquired by automated ...
Oh Tong In - - 2012
Efficient connection of multiple electrodes to the body for impedance measurement and voltage monitoring applications is of critical importance to measurement quality and practicality. Electrical impedance tomography (EIT) experiments have generally required a cumbersome procedure to attach the multiple electrodes needed in EIT. Once placed, these electrodes must then maintain ...
Chayer Boris - - 2012
Micro particle image velocimetry (µPIV) is a common method to assess flow behavior in blood microvessels in vitro as well as in vivo. The use of red blood cells (RBCs) as tracer particles, as generally considered in vivo, creates a large depth of correlation (DOC), even as large as the ...
Hong Hoang Thi Kim - - 2012
This study aims at characterizing NAD(P)H dehydrogenases on the inside and outside of the inner membrane of mitochondria of one phosphoenolpyruvate carboxykinase-crassulacean acid metabolism plant, Hoya carnosa. In crassulacean acid metabolism plants, NADH is produced by malate decarboxylation inside and outside mitochondria. The relative importance of mitochondrial alternative NADH dehydrogenases ...
Killaspy Helen - - 2012
OBJECTIVE: There have been few recent studies reporting on the outcomes for users of psychiatric rehabilitation services. This group has complex, longer-term mental health problems. We aimed to investigate 5-year outcomes for this group and identify factors associated with outcome. METHOD: Clinical outcome data on 141 users of a mental ...
Vornanen M - - 2012
AIM: Cardiac contraction and relaxation are mediated by rapidly changing calcium concentration around the myofibrils. In comparison with endotherms, ectothermic hearts are more strongly dependent on extracellular calcium for contraction suggesting this trait might represent the primitive vertebrate mode of cardiac activation. This study tests the hypothesis that intracellular calcium ...
Maeda Masazumi - - 2012
More than a century has passed since the first tracheoplasty was successfully performed by Eiselsberg in 1896. In that time, tracheobronchoplasty has developed with the extension of operative indications. This review focuses on who contributed to the development of this operation in Japan, and in what ways, with comparisons to ...
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