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Hultgren Rebecka - - 2012
A recent report unexpectedly revealed that one-fourth of abdominal aortic aneurysm (AAA) patients also have an aneurysm in the thoracic aorta (TAA). It remains to be investigated which AAA patients have a higher risk of also developing TAAs. The aim of this study was to identify possible differences in the risk factor ...
Boulton D W - - 2012
The antipsychotic, aripiprazole, plus lithium or valproate demonstrates rapid and significant improvement in manic symptoms that is sustained over the long term. A previous report showed that therapeutic doses of either lithium or valproate had no clinically significant effects on the pharmacokinetics of aripiprazole. We aimed to determine the effects ...
Pitoulias Georgios A - - 2012
Chronic contained rupture (CCR) of an abdominal aortic aneurysm is a rare condition, and differential diagnosis might be difficult. We present a clinical case of a hemodynamically stable octogenarian who presented with intermittent pain in the left lower abdomen. The patient had a history of diverticulitis, and 6 years ago, ...
Masoura S - - 2012
Pre-eclampsia is a unique disorder of human pregnancy with a great impact on maternal and perinatal morbidity and mortality worldwide and especially in developing countries. The aetiology is still unknown and the pathophysiology of the disease is the subject of extensive investigation. Recently, much of the interest of the investigators ...
Coulthard L R LR NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, - - 2012
Anti-tumour necrosis factor (TNF) biologics have revolutionized therapy of rheumatoid arthritis (RA). We compared the effects of infliximab on numbers of circulating leucocyte subsets in early RA (disease/symptom duration of ≤1 year) and late RA patients (>1 year). A control group consisted of early RA patients treated with a combination ...
Abreu J R F - - 2012
Beta cells presenting islet epitopes are recognized and destroyed by autoreactive CD8 T cells in type 1 diabetes. These islet-specific T cells are believed to react with epitopes binding with high affinity to human leucocyte antigen (HLA) expressed on beta cells. However, this assumption might be flawed in case of ...
Bandoli G - - 2012
Select social, behavioural and maternal characteristics were evaluated to determine if they were confounding factors in the association between paternity change and pre-eclampsia, small for gestational age (SGA) and pre-term delivery, in a sample of 1,409 women. Multivariate logistic regression analysis was used to determine if any of these risk ...
Komai Hiroyoshi - - 2012
We encountered two cases of spontaneous rupture of a saphenous vein bypass graft for lower-leg peripheral arterial disease possibly associated with collagen disease. Rupture occurred 5 and 14 days postoperatively. Neither case had any signs of infection, graft degeneration, or evident injury, but both were associated with collagen disease diagnosed at ...
Moore E S - - 2012
The use of cerclage, either through vaginal or abdominal routes, to assist in delaying pre-term delivery among select women with cervical insufficiency may be beneficial, but can also carry significant morbidity. Robotic-assisted transabdominal cervical cerclage (RoboTAC) in the non-pregnant patient has the ability to not only reduce associated morbidity, but ...
Michel Vera V Department of Biochemistry and Molecular Biology, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, - - 2013
Vacuolar ATPases (V-ATPases) comprise specialized and ubiquitously distributed pumps that acidify intracellular compartments and energize membranes. To gain new insights into the roles of V-ATPases in prostate cancer (PCa), we studied the effects of inhibiting V-ATPase pumps in androgen-dependent (LNCaP) and androgen-independent (C4-2B) cells of a human PCa progression model. ...
Savović Jelena J School of Social and Community Medicine, University of Bristol, Bristol, - - 2012
Published evidence suggests that aspects of trial design lead to biased intervention effect estimates, but findings from different studies are inconsistent. This study combined data from 7 meta-epidemiologic studies and removed overlaps to derive a final data set of 234 unique meta-analyses containing 1973 trials. Outcome measures were classified as ...
Jiang Xue-Feng - - 2012
Ultra-high-Q optical whispering gallery microcavities are promising platforms for fundamental studies and applied photonics. A new type of on-chip microcavity is experimentally realized, which features both highly unidirectional emission and ultra-high-Q factors exceeding 100 million in near infrared. By doping erbium into the microcavity, lasing emission in 1550 nm band ...
Valev V K - - 2012
Circularly polarized light can impart a sense of rotation on the electron density in ring-shaped gold nanostructures. V. K. Valev and co-workers show on p. OP208 that the near-field enhancement becomes more homogeneous on the surface of the nanostructures, thereby increasing the opportunity for interaction with molecules. This type of ...
Zheng Jian Yao - - 2012
A core/sheath structure is fabricated by decorating single-crystal organic nanowires with H(2) O(2) -reactive peroxalate ester, as reported by J. Yao, Y. S. Zhao, and co-workers on page OP194. The shell of the nanocable is highly sensitive and selective to the H(2) O(2) molecules, demonstrated by the generation of chemiluminescence ...
Schwarzenbach H R - - 2012
Based on the prevalence of asymptomatic kidney stones (5% in our general ward, in accordance with the literature) the value of abdominal ultrasonography in the clinical assessment of a suspected kidney-colic is discussed. The eminent importance of the stone-analysis is emphasized. In addition, the most common causes of kidney stone ...
Gassmann B - - 2012
Digitization is found everywehre in sonography. Printing of ultrasound images using the videoprinter with special paper will be done in single cases. The documentation of sonography procedures is more and more done by saving image sequences instead of still frames. Echocardiography is routinely recorded in between with so called R-R-loops. ...
da Silveira Vanessa Gass - - 2012
A Ketogenic Diet (KD) mimics the anticonvulsant effects of fasting, which are known to suppress seizures. The purinergic system has been investigated in the matter of epilepsy development, especially the nucleoside adenosine, which has been considered a natural brain anticonvulsant. During epileptic seizures, extracellular adenosine concentration rises rapidly to micromolar ...
Bhatia S K - - 2012
Alcaligenes sp. MTCC 10674 was isolated as acetone cyanohydrin hydrolyzing bacterium from soil of orchid gardens of Himachal Pradesh. Acetone cyanohydrin hydrolyzing activity of this organism comprised nitrile hydratase and amidase activities. It exhibited higher substrate specificity towards aliphatic hydroxynitrile (acetone cyanohydrin) in comparison to arylaliphatic hydroxynitrile. Isobutyronitrile (40 mM) acted ...
Blank W - - 2012
Ultrasonic examination of the thyroid is essential in any diagnostic process on the thyroid. It helps to meet the challenge of identifying the few malignant among the thousands of benign nodules. Besides tumour infiltration in surrounding tissue and lymph node metastases - which may prove thyroid cancer - there are ...
Núñez-Nogueira Gabriel - - 2012
Environmental metal pollution is one of the major problems faced by humankind. This type of pollution affects aquatic systems (estuaries, coastal lagoons, etc.), which are very dynamic systems, therefore making the study of the effects on the organisms that inhabit them an essential issue. In this study, the capacity of ...
Risio M - - 2012
Adenomas represent the morphological precursors of the vast majority of colorectal cancers: although every adenoma has the capacity of malignant evolution, most adenomas stabilize their progression or even regress. Pathological factors are predictive of the natural history of adenomas in terms of potential and time interval for becoming malignant. Regression ...
Wilhelm C - - 2012
To defect incidence of development hip dysplasia by hip ultrasound and to determine efficacy of early treatment: a pilot study in Ulan Bator, Mongolia. Until recently, in Mongolia, early detection and treatment of DDH (developmental dysplasia of the hip) in the first months of life was not possible. A high ...
Kim Dong Hyun - - 2012
Smoking has long been associated with osteoporosis, decreased bone mineral density, increased risk of bone fracture, and increased health costs. Nicotine, the main component of cigarette smoke, has major negative effects on bone metabolism and skeletal remodeling in vivo. Although osteoblasts and osteoblast-like cells have been used extensively to study ...
Hagara D - - 2012
Ultrasound-based technologies are competing more and more success-fully against computerized tomography and magnetic resonance based imaging procedures. This thanks to technological improvements as well as accumulating evidence, stemming from properly conducted controlled clinical studies. The reduced cost and radiation safety issues are additional arguments in its favor. This article reviews ...
Gysel W - - 2012
Ultrasound is poorly established in East Africa because of missing finances and medical staff. The Foundation for medical know how transfer SmW installed in the last 3 years an ultrasound departement in all District Hospitals in the South Province Mombasa in Kenya and was teaching the medical staff 2-3 times ...
Abdel Moneim Ahmed E - - 2012
Studies have shown that pomegranate, Punica granatum Linn. (Lythraceae), has remarkable biological and medicinal properties. However, the effects of pomegranate peel methanolic extract (PPME) on the aluminum-induced oxidative stress and histopathological change have not been reported yet. To determine the effect of PPME (200 mg/kg bwt) on the aluminum chloride (AlCl(3); ...
Schellhaas S - - 2012
Focused ultrasound is a key methodology of critical care medicine. By referencing few ultrasound differential diagnosis, it is possible to identifying in real-time the reason of the critical state of a patient. Therefore typical focused ultrasound protocols were developed. The well known Focused Assessment with Sonography for trauma (FAST) was ...
Rosenberg I - - 2012
The correct setting of the ultrasound equipment is a perequisite for a high quality of the ultrasound examination. Both the B-mode ultrasonography, as well as the Doppler technique offer interesting alternative settings that are often inadequately used. This brief summary of basic settings should help the practicing clinicians in everyday ...
Dietschi A - - 2012
Since the early 1990's, ultrasound through the development of high-resolution probes in the musculoskeletal system has become more and more important. The development of ultrasound technology has gone hand in hand with the development of know-how in different clinical fields, so that diagnostic ultrasound has now become an indispensable diagnostic ...
Dietrich C F - - 2012
Recently the «EFSUMB guidelines and recommendations on the clinical practice of contrast enhanced ultrasound (CEUS): Update 2012 on non-hepatic applications» have been published. In the following paper a short summary and comments on the guidelines are given.
Gabardi S S Dipartimento di Scienza dei Materiali, Università di Milano-Bicocca, Milano, - - 2012
We generated models of the amorphous phase of Sb-rich GeSbTe phase change alloys by quenching from the melt within density functional molecular dynamics. We considered the two compositions Ge(1)Sb(1)Te(1) and Ge(2)Sb(4)Te(5). Comparison with previous results on the most studied Ge(2)Sb(2)Te(5) allowed us to draw some conclusions on the dependence of ...
Soler Laia - - 2012
This study aims to provide evidence concerning the effects of experiencing multiple forms of victimization (poly-victimization) on self-esteem and post-traumatic stress symptoms in Spanish adolescents. A total of 722 adolescents were recruited from seven secondary schools in Catalonia, Spain. The Rosenberg Self-Esteem Scale, the Youth Self Report and the Juvenile ...
Davoll Sabine - - 2012
OBJECTIVES: The purpose of this study was to analyse the extent to which breast cancer patients excuse inconveniences that occur during their hospitalisation, and how this "tendency to excuse" affects their satisfaction with the hospital stay. METHODS: Breast cancer patients undergoing treatment at one of 51 breast centres in North ...
O'Keeffe M - - 2012
Humans have an innate requirement for sleep that is intrinsically governed by circadian and endocrine systems. More recently, reduced sleep duration has gained significant attention for its possible contribution to metabolic dysfunction. Significant evidence suggests that reduced sleep duration may elevate the risk for impaired glucose functioning, insulin resistance and ...
Rahmioglu Nilufer - - 2012
Atypical cytochrome P450 3A4 (CYP3A4) enzyme activity-induced and inhibited-is thought to be the driver of numerous poor or adverse therapeutic responses to up to 50 % of all commonly prescribed drugs. We carried out a genome-wide association study to identify common genetic variants associated with variation in induced CYP3A4 activity. A ...
Demirel Gamze - - 2012
Our aim was to assess trends in neonatal mortality in 2009, evaluate advances in health policy, determine new goals to preserve a higher quality health service, and to prevent neonatal deaths. Data were gathered from the system of the General Directorate of Mother and Child and Family Planning. Maternal age, ...
Lee Min Ho - - 2012
Objective: To investigate the hepatoprotective effect, safety and tolerability of oral preparation comprising dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate (DDB) plus garlic oil (GO) in chronic hepatitis patients. Methods: In this double-blind, placebo-controlled clinical trial conducted for 6 weeks with 1-week follow-up, a total of 88 patients with histologically confirmed chronic hepatitis and persistently ...
Zheng Shou-Tian - - 2012
During the past decade, research into transition-metal-substituted polyoxometalate self-assembly has been greatly developed. This review summarizes the conventional solution syntheses and hydrothermal syntheses of novel substituted polyoxometalates based on the incorporation of paramagnetic transition metals Mn, Fe, Co, Ni, and Cu, with an emphasis on the variety of nuclearities and ...
Tsai Ching-Wei - - 2012
In this study, the relationship of the structural stability of peptide diastereomers in elution solvents and their retention behaviors in reversed-phase chromatography (RPC) was examined to provide guidance on the solvent selection for a better separation of peptide diastereomers. We investigated the chromatographic retention behaviors of exenatide, a peptide drug ...
Newman Nancy J - - 2012
The hereditary optic neuropathies are inherited disorders in which optic nerve dysfunction is a prominent feature in the phenotypic expression of disease. Optic neuropathy may be primarily an isolated finding, such as in Leber hereditary optic neuropathy and dominant optic atrophy, or part of a multisystem disorder. The pathophysiological mechanisms ...
Peng Chiung-Chi - - 2012
SCOPE: The number of patients with chronic kidney disease (CKD) are increasing. Interventions such as controlling hypertension and specific pharmacologic options are recommended. Some nutraceutics may have benefits in this regard. METHODS AND RESULTS: Naringenin (a flavanon), catechin (a flavanol), and quercetin (a flavonol) and rutin (a flavonol rutinoside) were ...
Nouri Alireza - - 2012
In the present study, the effect of N,N-dimethylaminoethyl methacrylate (DMAEMA) conjugation onto branched poly(ethylenimine) (PEI) with different grafting degree was examined for gene delivery applications. The DMAEMA-grafted-PEI conjugates were characterized and complexed with plasmid DNA (pDNA) at various concentrations, and the physicochemical properties, cell viability, and in vitro transfection efficiency ...
Kanazawa Keisuke - - 2012
Abstract Objective. There is no comparative study of electronic radial endoscopic ultrasonography (ER-EUS) and electronic curvilinear EUS (EC-EUS). The aim of this study was to compare the accuracy of ER-EUS and EC-EUS for detecting pancreatic malignancies. Methods. This was a retrospective review of the patients who had EUS assessment from ...
Ericsson Hans - - 2012
Objectives: AZD1656 is a novel glucokinase activator with a postulated dual mechanism of action by activating glucokinase in both the pancreas and the liver, and with the potential to deliver effective glucose-lowering in Type 2 diabetes mellitus. Here, we present the tolerability, pharmacokinetics and pharmacodynamics of AZD1656 in two single-blind, ...
Gachard N - - 2013
To clarify the relationships between marginal zone lymphomas (MZLs) and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas (WM/LPLs), immunoglobulin heavy chain variable gene (IGHV) features were analyzed and the occurrence of MYD88 L265P mutations was identified in a series of 123 patients: 53 MZLs from the spleen (SMZLs), 11 from lymph nodes (NMZLs), 28 ...
Donahue Leah Rae LR Mutant Mouse Regional Resource Center (MMRRC), The Jackson Laboratory, Bar Harbor, ME, USA. - - 2012
Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these ...
Chen Xiao - - 2012
Marine methane bubbles are absorbed, steadily stored and continuously transported based on the employment of superhydrophobic sponges. antiwetting sponges are water-repellent in the atmosphere and absorb gas bubbles under water. Their capacity to store methane bubbles increases with enhanced submerged depth. Significantly, trapped methane bubbles can be continuously transported driven ...
Schnetz-Boutaud Nathalie C - - 2012
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory and cognitive impairment and is the leading cause of dementia in the elderly. A number of genome wide association studies and subsequent replication studies have been published recently on late onset AD (LOAD). These studies identified several new susceptibility ...
Erk Thomas - - 2012
SCOPE: Until now, the question of how the ingested doses of chlorogenic acids (CGA) from coffee influence their absorption and metabolism remains unresolved. To assess absorption in the small intestine, we performed a dose-response study with a randomized, double-blinded, crossover design with ileostomist subjects. METHODS AND RESULTS: After a polyphenol-free ...
Rock Kenneth L - - 2013
Uric acid is a waste product of purine catabolism. This molecule comes to clinical attention when it nucleates to form crystals of monosodium urate (MSU) in joints or other tissues, and thereby causes the inflammatory disease of gout. Patients with gout frequently suffer from a number of comorbid conditions including ...
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