Search Results
Results 301 - 350 of 2998
< 2 3 4 5 6 7 8 9 10 11 12 >
Gu Z Z Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, - - 2013
During lung development, cells proliferate for a defined length of time before they begin to differentiate. Factors that control this proliferative process and how this growth process is related to lung cancer are currently unknown. Here, we found that the WD40-containing protein (p44/wdr77) was expressed in growing epithelial cells at ...
Tomkiewicz C - - 2012
The aryl hydrocarbon receptor (AhR) is commonly described as a transcription factor, which regulates xenobiotic-metabolizing enzymes. Recent studies have suggested that the binding of ligands to the AhR also activates the Src kinase. In this manuscript, we show that the AhR, through the activation of Src, activates focal adhesion kinase ...
Jones C K - - 2012
The last decade's unprecedented rise in litter size has led to a perceived rise in the number of fallback pigs. However, there is little peer-reviewed data available regarding the biological differences between fallback pigs and their normal cohorts. Therefore, the objective of this experiment was to identify differences in the ...
Leiros Hanna-Kirsti S - - 2012
Metallo-β-lactamase (MBL) genes confer resistance to virtually all β-lactam antibiotics and are rapidly disseminated by mobile genetic elements in Gram-negative bacteria. MBLs belong to three different subgroups, B1, B2, and B3, with the mobile MBLs largely confined to subgroup B1. The B3 MBLs are a divergent subgroup of predominantly chromosomally ...
Wang Peijian - - 2012
Type 2 diabetes mellitus (T2DM) is rapidly prevailing as a serious global health problem. Current treatments for T2DM may cause side effects, thus highlighting the need for newer and safer therapies. We tested the hypothesis that dietary capsaicin regulates glucose homeostasis through the activation of transient receptor potential vanilloid 1 ...
Hanaoka Mitsumasa - - 2012
The circadian clock of cyanobacteria is composed of KaiA, KaiB, and KaiC proteins, and the SasA-RpaA two-component system has been implicated in the regulation of one of the output pathways of the clock. In this study, we show that another response regulator that is essential for viability, the RpaA paralog, ...
Yu Xiao Dan - - 2012
OBJECTIVE:The relationship between gestational hypertension, preeclampsia, and the risk of retinopathy of prematurity (ROP) remains unclear. Thus, we used a large cohort database to study the influence of maternal gestational hypertension and preeclampsia on the occurrence of ROP in preterm infants.METHODS:We used data from a previous retrospective cohort study that ...
Nakamura Keiji - - 2012
Clostridium botulinum types C and D cause animal botulism by the production of serotype-specific or mosaic botulinum neurotoxin (BoNT). The D/C mosaic BoNT (BoNT/DC), which is produced by the isolate from bovine botulism in Japan, exhibits the highest toxicity to mice among all BoNTs. In contrast, rats appeared to be ...
Vercelli Barbara - - 2012
Mono- and multilayers from CdSe nanocrystal dispersion and perylene tetracarboxylate solution are reported for the first time. The layers were investigated by UV-visible spectroscopy, cyclic voltammetry, photoconductivity and photoelectrochemical techniques. The n-type organic semiconductor gives enhanced photoconductivity to the CdSe-NC multilayer structure. The photoactive perylene monolayer acts also as hypersensitizer ...
Newell Dennis L - - 2012
Leakage of CO2 and brine from geologic storage reservoirs along wellbores is a major risk factor to the success of geologic carbon sequestration. We conducted multiphase [supercritical (sc)CO2-brine] coreflood experiments that simulate a leakage pathway along the cement/rock interface. A composite core constructed of oil-well cement and siltstone separated by ...
Ishikawa Y - - 2012
The tumor suppressor Fbxw7 (also known as Sel-10, hCdc4, hAgo, or Fbw7) is an F-box protein that functions as the substrate-recognition subunit of an SCF ubiquitin ligase complex and targets a group of oncoproteins for degradation. We now show that Fbxw7 regulates the proliferation and differentiation of keratinocytes by mediating ...
Mulliniks J T - - 2012
Body condition score is used as a management tool to predict competency of reproduction in beef cows. Therefore, a retrospective study was performed to evaluate association of BCS at calving with subsequent pregnancy rate, days to first postpartum ovulation, nutrient status (assessed by blood metabolites), and calf BW change in ...
Bernhard B C - - 2012
Crossbred steers (n = 180; 230 ± 6 kg) were fed during a 56-d receiving period to determine if supplementing chromium (Cr; KemTRACE®(brand)ChromiumPropionate 0.04%, Kemin Industries) would improve feedlot performance and health of newly-received cattle. A completely randomized block design (36 pens; 9 pens/treatment; 5 steers/pen) was used. Chromium premixes ...
Lekprasert Banyat - - 2012
Polarized Raman micro-spectroscopy and atomic force microscopy were used to obtain quantitative information regarding the molecular structure of individual diphenylalanine (FF) nano- and microtubes. The frequencies of the Raman spectral bands corresponding to the amide I (1690cm-1) and amide III (1249cm-1) indicated that the FF-molecules interact by hydrogen bonding at ...
Davis Vicki L - - 2012
Abstract Multiple platelet-rich preparations have been reported to improve wound and bone healing, such as platelet-rich plasma (PRP) and platelet rich fibrin (PRF). The different methods employed during their preparation are important as they influence the quality of the product applied to a wound or surgical site. Besides the general ...
Liang Lan - - 2012
OBJECTIVE:Examine the rate of screening for adolescent overweight and obesity by pediatric health care professionals and the provision of advice on healthy eating and physical activity.METHODS:Our sample contains adolescents 11 to 17 years old (6911 girls and 6970 boys) from the 2001-2007 Medical Expenditure Panel Survey who reported having at ...
Lincoln Tania M - - 2012
Objective: Randomized controlled trials have attested the efficacy of cognitive behavioral therapy (CBT) in reducing psychotic symptoms. Now, studies are needed to investigate its effectiveness in routine clinical practice settings. Method: Eighty patients with schizophrenia spectrum disorders who were seeking outpatient treatment were randomized to a specialized cognitive behavioral intervention ...
Dehghan Nayeri Nahid - - 2012
Abstract Objective: The aim of this study was to compare the effects of telephone consultation and attendance education on the quality of life of patients with hepatitis B or C receiving interferon therapy. Subjects and Methods: Through a quasi-experimental study, 80 hepatitis patients were randomly assigned to one of the ...
John Alex - - 2012
A series of cyclometallated palladium complexes derived from O-phenylcarbamates have been synthesized by the reaction of the respective carbamates with Pd(OAc)2 in the presence of acids, CF3CO2H, CF3SO3H and p-TsOH. The palladacycles were observed to coordinate amines and electron rich anilines but not sulfonamides or carboxamides. Analysis of the tBu-NH2 ...
Kim Young-Min - - 2012
Here, we describe a concept for localized and long-term delivery of short interfering RNA (siRNA) using injectable polyplex hydrogel possessing thermosensitivity and biodegradability properties. We prepared a low molecular weight polyethyleneimine (L-PEI)-poly(organophosphazene) conjugate as a thermosensitive and cationic polymer that has a cleavable ester linkage. The conjugates formed about 100 ...
Bravo-Abad Jorge - - 2012
Many of graphene's unique electronic properties emerge from its Dirac-like electronic energy spectrum. Similarly, it is expected that a nanophotonic system featuring Dirac dispersion (two conical bands touching at a single point, the so-called Dirac point) will open a path to a number of important research avenues. To date, however, ...
Berhow Mark A - - 2012
Abstract Rosmarinic acid (RA) is an important antioxidant polyphenol that is found in a variety of spices and herbs, including Ocimum canum Sims (locally called eme or akokobesa in Ghana). Aqueous extracts from the leaves of O. canum are used as an antidiabetic herbal medicine in Ghana. Analytical thin-layer chromatography ...
Peel R K - - 2012
The objective of this study was to evaluate the effects of overfeeding naturally-mated adolescent ewes on maternal, fetal, and postnatal lamb growth, hormone concentrations, and lamb carcass characteristics. Two experiments were conducted in which singleton-bearing adolescent ewes were fed a diet containing 2.72 Mcal/kg ME at a rate which met ...
Sukitpaneenit Panu - - 2012
The development of high-performance and well-constructed thin-film composite (TFC) hollow fiber membranes for forward osmosis (FO) applications is presented in this study. The newly developed membranes consist of a functional selective polyamide layer formed by highly reproducible interfacial polymerization on a polyethersulfone (PES) hollow fiber support. Using dual-layer co-extrusion technology ...
Hales Ke - - 2012
The growing ethanol industry in the Southern Great Plains has recently increased the use of wet distillers grains with solubles (WDGS) in beef cattle finishing diets. Two experiments were conducted to evaluate odorous compound production in urine and feces of feedlot steers fed diets with different concentrations of WDGS and ...
Pereira Cassiano Costa Silva - - 2012
Abstract The piezosurgery is a new and modern technique of bone surgery in implantology. Selective cuttiing is possible for different ultrasonic frequencies acting only in hard tissues (mineralized), saving noble anatomical structures. With the piezoelectric osteotomy technique, the preparation of receptor sites for implants, obtaining autogenous bone graft (particles and ...
Sahadevan Sudeep - - 2012
In biological research, establishing the prior art by searching and collecting information already present in the domain has equal importance as the experiments done. To obtain a complete overview about the relevant knowledge, researchers mainly rely on two major information sources: (i) various biological databases and (ii) scientific publications in ...
Jain Avijita - - 2012
A series of dipeptide substituted nickel complexes with the general formula, [Ni(P(Ph)(2)N(NNA-amino acid/ester)(2))(2)](BF(4))(2), have been synthesized and characterized (P(2)N(2) = 1,5-diaza-3,7-diphosphacyclooctane, and the dipeptide consists of the non-natural amino acid, 3-(4-aminophenyl)propionic acid (NNA), coupled to amino acid/esters = glutamic acid, alanine, lysine, and aspartic acid). Each of these complexes is an ...
Rosenthal Ian M - - 2012
In previous experiments, replacing the 10-mg/kg of body weight daily dose of rifampin with 7.5 to 10 mg/kg of rifapentine in combinations containing isoniazid and pyrazinamide reduced the duration of treatment needed to cure tuberculosis in BALB/c mice by approximately 50% due to rifapentine's more potent activity and greater drug ...
Merten Christian - - 2012
In the present work, the first observation of strong resonance Raman optical activity (RROA) involving more that one resonant electronic state is reported. The chiral transition metal complex bis-(trifluoroacetylcamphorato)-copper(II), abbreviated Cu(tfc)2, exhibits both resonance Raman (RR) and RROA spectra with laser excitation at 532 nm. Vibrational assignments for this complex ...
Thomas Rajan M - - 2012
Naive CD4(+) T cells can differentiate into distinct lineages with unique immune functions. The cytokines TGFβ and IL-6 promote the development of Th17 cells that produce IL-17, an inflammatory cytokine not expressed by other T helper lineages. To further understand how IL-17 production is controlled, we studied an ~120-kb genomic ...
Nooner Kate B - - 2012
Studies of posttraumatic stress disorder (PTSD) in adolescence published from 2000 to 2011 indicate that adolescents are at greater risk of experiencing trauma than either adults or children, and that the prevalence of PTSD among adolescents is 3-57%. Age, gender, type of trauma, and repeated trauma are discussed as factors ...
Sheeber Lisa B - - 2012
Develop and pilot an Internet-facilitated cognitive-behavioral treatment intervention for depression, tailored to economically disadvantaged mothers of young children. Mothers (N = 70) of children enrolled in Head Start, who reported elevated levels of depressive symptoms, were randomized to either the 8-session, Internet-facilitated intervention (Mom-Net) or delayed intervention/facilitated treatment-as-usual (DI/TAU). Outcomes ...
Norris Dennis - - 2012
The goal of research on how letter identity and order are perceived during reading is often characterized as one of "cracking the orthographic code." Here, we suggest that there is no orthographic code to crack: Words are perceived and represented as sequences of letters, just as in a dictionary. Indeed, ...
Teixeira Silvania Silva - - 2012
Thyroid hormones (THs) act genomically to stimulate glucose transport by elevating glucose transporter (Slc2a) expression and glucose utilization by cells. However, nongenomic effects of THs are now emerging. Here, we assess how triiodothyronine (T(3)) acutely affects glucose transport and the content of GLUT4, GLUT1, and GLUT3 at the surface of ...
Willis Jason A - - 2012
To explore the effects of single-nucleotide polymorphisms (SNP) on pancreatic cancer risk and overall survival (OS). The germ line DNA of 531 pancreatic cancer cases and 305 healthy controls from a hospital-based study was genotyped at SNPs previously reported to be associated with pancreatic cancer risk or clinical outcome. We ...
Li N - - 2012
SUMMARY This study examined the effect of phosphoric acid (PA) etching on the bond strength and acid-base resistant zone (ABRZ) formation of a two-step self-etching adhesive (SEA) system to enamel. An etch-and-rinse adhesive (EAR) system Single Bond (SB) and a two-step SEA system Clearfil SE Bond (SE) were used. Human ...
Kern Jan - - 2012
Most of the dioxygen on earth is generated by the oxidation of water by photosystem II (PS II) using light from the sun. This light-driven, four-photon reaction is catalyzed by the Mn(4)CaO(5) cluster located at the lumenal side of PS II. Various X-ray studies have been carried out at cryogenic temperatures to ...
Warner Jamie H - - 2012
We distinguish between Bernal and rhombohedral stacked trilayer graphene using aberration-corrected high-resolution transmission electron microscopy. By using a monochromator to reduce chromatic aberration effects, angstrom resolution can be achieved at an accelerating voltage of 80 kV, which enables the atomic structure of ABC rhombohedral trilayer graphene to be unambiguously resolved. ...
Wan Lijuan - - 2012
A series of novel bis-pyrazole/pyridine complexes, [Zn(2)(HL(1))(2)(μ(2)-SO(4))](2)·EtOH·H(2)O (1), [Co(2)(HL(1))(2)(μ(2)-SO(4))](2)·2DMF·6H(2)O (2), [Zn(4)(HL(1))(4)(μ(4)-SO(4))][OH](2) (3), [Zn(2)(HL(2))(2)(μ(2)-SO(4))]·2H(2)O (4), [Zn(H(2)L(2))(H(2)O)(2)](SO(4))·0.87H(2)O (5) (H(2)L(1) = 2,6-di-(5-phenyl-1H-pyrazol-3-yl)pyridine, H(2)L(2) = 2,6-di-(5-methyl-1H-pyrazol-3-yl)pyridine), were synthesized hydrothermally from the self-assembly of Zn(II) or Co(II) with different types of bipyrazolyl/pyridine derivative ligands. All the complexes were characterized by elemental analysis, IR and UV-vis ...
Guo Sheng-Ping - - 2012
Eight new rare-earth metal-lithium-germanides belonging to the [REGe(2)](n)[RELi(2)Ge](m) homologous series have been synthesized and structurally characterized by single-crystal X-ray diffraction. The structures of the title compounds can be rationalized as linear intergrowths of imaginary RELi(2)Ge (MgAl(2)Cu structure type) and REGe(2) (AlB(2) structure type) slabs. The compounds with general formula RE(7)Li(8)Ge(10) ...
Felix T L - - 2012
Two experiments were conducted to evaluate the effects of monensin and dried distillers grains with solubles (DDGS) on ruminal metabolism in 8 fistulated steers. In Exp. 1, treatments were (DM basis): (1) 0 mg monensin/kg diet DM, (2) 22 mg monensin/kg diet DM, (3) 33 mg monensin/kg diet DM, and ...
Peters S O - - 2012
Data from developing Brangus heifers (3/8 Brahman-Bos indicus x 5/8 Angus- Bos taurus; n ≈ 802 from 67 sires) registered with International Brangus Breeders Association were analyzed to detect QTL associated with growth traits and ultrasound measures of carcass traits. Genotypes were from BovineSNP50 (Infinium BeadChip, Illumina, San Diego, CA; ...
Liu Jia - - 2012
We examined the effect of three clinically used antimicrobials on Streptococcus mutans UA159 biofilm detachment under flow conditions. Sodium fluoride (NaF) and chlorhexidine at MIC levels promoted biofilm detachment and inhibited detachment when concentrations were higher than the MIC and reduced detached-cell viability only at high concentrations. Ampicillin at all ...
Lesoine John F - - 2012
We present a method for measuring the fluorescence from a single molecule hundreds of times without surface immobilization. The approach is based on the use of electroosmosis to repeatedly drive a single target molecule in a fused silica nanochannel through a stationary laser focus. Single molecule fluorescence detected during the ...
Reizis Boris - - 2012
Despite the critical role of classical dendritic cells (cDCs) in the initiation of adaptive immune responses, the genetic and phenotypic definition of cDCs remains moot. Two new studies designate Zbtb46 as a novel transcription factor that is specifically expressed in all cDCs in both humans and mice. Although Zbtb46 appears ...
Salih Tamir - - 2012
OBJECTIVES: The prognostic significance of the circumferential resection margin (CRM) status in oesophageal cancer patients treated with neo-adjuvant chemotherapy and radical resection is controversial. Furthermore, it is currently unclear whether patients with cancer located at the CRM have a prognosis different from that of those with cancer within 1 mm of ...
Yoong Pauline - - 2012
The Panton-Valentine leukocidin (PVL) is a cytotoxin expressed by many methicillin-resistant Staphylococcus aureus (MRSA) strains that cause community-acquired infections (CA-MRSA). Its role in virulence however, is controversial, with clinical data suggesting that PVL-producing strains may cause less severe disease in humans. PVL is capable of lysing human white blood cells, ...
Xu Ligang - - 2012
Anti-fogging and -reflection coatings were fabricated on glass and poly(methyl methacrylate) (PMMA) substrates by integrating solid silica nanoparticles of 25 nm (S-25) and mesoporous silica nanoparticles (MSNs) of 45 nm via layer-by-layer assembly without any post-treatments. Superhydrophilicity and a maximum transmittance of 98.5% in the visible spectral range was achieved ...
Mueller Ivo - - 2012
Genotyping Plasmodium falciparum parasites in longitudinal studies provides a robust approach to estimating force of infection (FOI) in the presence of superinfections. The molecular parameter (mol)FOI, defined as the number of new P. falciparum clones acquired over time, describes basic malaria epidemiology and is suitable for measuring outcomes of interventions. ...
< 2 3 4 5 6 7 8 9 10 11 12 >