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Results 251 - 300 of 1477
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Kampfer C - - 2012
Fibrosis, increased amounts of immune cells and expression of COX-2 in the testes of infertility patients provide circumstantial evidence for a specific testicular milieu, in which reactive oxygen species (ROS) could be increased. If ROS level increase and/or ROS scavengers decrease, the resulting testicular oxidative stress may contribute to human ...
De Vecchis Renato - - 2012
BACKGROUND: In chronic heart failure patients (CHF), ultrasound measurement of inferior vena cava collapsibility index (IVCCI) has been proposed to yield careful assessment and grading of the hemodynamic congestion. OBJECTIVE: The purpose of this study was to correlate the findings of physical examination with IVCCI in CHF patients. METHODS: According ...
Leon Iker - - 2012
Mass-resolved excitation spectroscopic techniques are usually limited to systems with a chromophore, i.e.,a functional group with electronic transitions in the VIS/UV, with lifetimes from hundreds of picoseconds to some microseconds. In this paper we expand such techniques to any system, by using a combination of ns IR pulses with non-resonant ...
Ay Y - - 2012
Monitoring factor replacement treatment and observing concordance with clinical haemostasis is crucial in vital haemorrhages and major surgeries in haemophilic patients. We aimed to investigate the value of the thrombin generation assay (TGA) and thromboelastography (TEG) for monitoring haemostasis in haemophilic patients during factor replacement treatment. The study group consisted ...
Falcaro Paolo - - 2012
The tuneable pore size and architecture, chemical properties and functionalization make metal organic frameworks (MOFs) attractive versatile stimuli-responsive materials. In this context, MOFs hold promise for industrial applications and a fervent research field is currently investigating MOF properties for device fabrication. Although the material properties have a crucial role, the ...
Henderson Marsha D - - 2012
  To quantify and compare diagnoses according to race in pediatric Health Maintenance Organization (HMO) health plan patients seen in a general dermatology clinic over a 10-year period. Retrospective cohort of health plan pediatric patients seen in the dermatology clinic between 1997 and 2007 was established using an electronic medical ...
Reynisson Eyjólfur - - 2012
AIMS: To study the succession of cultivated and uncultivated microbes during the traditional curing process of skate. METHODS AND RESULTS: The microbial diversity was evaluated by sequencing 16S rRNA clone libraries and cultivation in variety of media from skate samples taken periodically during a 9 day curing process. A pH ...
Tinker Sarah C - - 2012
BACKGROUND: Obesity is associated with an increased risk of having a pregnancy affected by a neural tube defect (NTD). It is not clear whether the amount of folic acid required by obese women to protect against NTDs is the same as that for nonobese women. METHODS: We analyzed data from ...
Poore Alistair G B - - 2012
Despite the importance of consumers in structuring communities, and the widespread assumption that consumption is strongest at low latitudes, empirical tests for global scale patterns in the magnitude of consumer impacts are limited. In marine systems, the long tradition of experimentally excluding herbivores in their natural environments allows consumer impacts ...
Chen Lei-Chin - - 2012
The alternative transcription factor σ(B) of Bacillus cereus controls the expression of a number of genes that respond to environmental stress. Four proteins encoded in the sigB gene cluster, including RsbV, RsbW, RsbY (RsbU) and RsbK, are known to be essential in the σ(B) -mediated stress response. In the context ...
Dobler Ina M - - 2012
Research in the past four decades has repeatedly shown that selective retrieval of some (non-target) memories can impair subsequent retrieval of other (target) information, a finding known as retrieval-induced forgetting. More recently, however, there is evidence that selective retrieval can both impair and enhance recall of related memories (K-H. T. ...
Jemel Sara - - 2012
Aortic graft infection, one of the most common fatal complications of aortovascular surgery, is managed mainly by the removal of infected graft material and re-establishment of vascular continuity using an extra-anatomical bypass or in situ graft replacement. Despite significant progress in perioperative, surgical, and medical treatments, the mortality and morbidity ...
Leahy Siobhan - - 2012
Anthropometric data indicate that the human phenotype is changing. Today's adult is greater in stature, body mass and fat mass. Accurate measurement of body composition is necessary to maintain surveillance of obesity within the population and to evaluate associated interventions. The aim of the present study was to construct and ...
Beitz Analena - - 2012
The aim of this randomized study was to determine whether intervention based on additional capnographic monitoring reduces the incidence of arterial oxygen desaturation during propofol sedation for colonoscopy. Patients (American Society of Anesthesiologists classification (ASA) 1-3) scheduled for colonoscopy under propofol sedation were randomly assigned to either a control arm ...
Ku C S - - 2012
The study of de novo point mutations (new germline mutations arising from the gametes of the parents) remained largely static until the arrival of next-generation sequencing technologies, which made both whole-exome sequencing (WES) and whole-genome sequencing (WGS) feasible in practical terms. Single nucleotide polymorphism genotyping arrays have been used to ...
Rebollar Eria A - - 2012
The evolutionary history and ecological differentiation of the genus Exiguobacterium was characterized within natural communities from the Cuatro Cienegas Basin, Mexico. Exiguobacterium comprises both halophilic and alkaliphilic bacteria that are abundant among the aquatic systems of the Cuatro Cienegas Basin. We obtained complete sequences of the 16srRNA gene and partial ...
Weickert Martin O - - 2012
Insulin resistance (IR) has been proposed as the strongest single predictor for incident Type 2 Diabetes and is mainly caused by adiposity as a result of chronic excessive energy intake. Loss of body weight and fat mass improve insulin sensitivity. However, independent of energy intake and changes in body weight/composition, ...
Boer-Martins Leandro - - 2012
BACKGROUND: The finding of adipocyte-derived hormone leptin as an overstimulator of sympathetic activity brought a new perspective to the pathophysiological mechanisms of obesity-hypertension. OBJECTIVES: As aldosterone also increases sympathetic activity, we aimed to assess the relationship between sympathetic overactivity and plasma leptin and aldosterone levels in resistant hypertension (RHTN), comparing ...
Mishina Hiroki - - 2012
Objectives  To determine IMR trends and regional variations among 47 prefectures in Japan and to identify associated population-based factors. Methods  We conducted an ecological study of infant mortality rate (IMR) by analyzing publicly available data from the Ministry of Health, Labour and Welfare of Japan. Outcome measure for trend is ...
Müllner Markus - - 2012
High-aspect-ratio rutile and anatase hybrid nanowires are produced via a template-directed process using a novel cylindrical polyelectrolyte brush template. Loading the highly negatively charged 1D templates with pre-synthesized TiO(2) nanocrystals, results in the fabrication of soluble crystalline TiO(2) hybrid nanowires.
Nacar Alper Buğra - - 2012
Background: Prolonged atrial conduction time measured by tissue Doppler imaging (TDI) has been associated with increased risk of atrial fibrillation. We aimed to evaluate the effect of subclinical hyperthyroidism (SH) and antithyroid treatment on atrial conduction time. Methods: A total of 30 patients with SH (26 females; mean age 34.8 ...
Said Sameh M - - 2012
Abstract  Background: Apical and midventricular hypertrophic cardiomyopathy (HCM) are rare variants of HCM, in which the hypertrophy is located mainly at the midventricular to apical levels. Heart transplantation was the only possible surgical solution for many of these patients; however, transapical myectomy represents another good alternative. We present our surgical ...
Shivkumar Sushmita - - 2012
OBJECTIVES:Three-hundred fifty million people worldwide are chronically infected with Hepatitis B, with four million acute infections annually. With infection concentrated in hard-to-reach populations and low resource settings, rapid point-of-care (POC) tests offer an efficient screening alternative to laboratory tests. We conducted a meta-analysis to evaluate accuracy of rapid POC tests ...
Montgomery Neil A - - 2012
Star-shaped molecules are of growing interest as organic optoelectronic materials. Here a detailed study of their photophysics using fluorescence depolarisation is reported. Fluorescence depolarisation dynamics are studied in branched oligofluorene-truxene molecules with a truxene core and well-defined three-fold symmetry, and are compared with linear fluorene oligomers. An initial anisotropy value ...
Joham A E - - 2012
Pigment epithelium-derived factor (PEDF) is upregulated in obese rodents and is involved in the development of insulin resistance (IR). We aim to explore the relationships between PEDF, adiposity, insulin sensitivity and cardiovascular risk factors in obese women with Polycystic Ovary Syndrome (PCOS) and weight-matched controls and to examine the impact ...
Hsieh I-Hui - - 2012
Frequency modulation (FM) and amplitude modulation are the two building blocks of all complex sounds. Directional FM sweeps are especially pervasive in speech, music, animal vocalizations, and other natural sounds. Although the existence of FM-selective cells in the auditory cortex of animals has been documented, evidence in humans remains equivocal. ...
Esser Dominik - - 2012
Protein phosphorylation, is known to occur in Archaea. However, knowledge of phosphorylation in the third domain of life is rather scarce. Homology based searches of archaeal genome sequences reveals the absence of two component systems in crenarchaeal genomes, but the presence of eukaryotic like protein kinases and protein phosphatases. Here, ...
Thompson M - - 2012
Zoonotic diseases impact both wild and domestic animal populations and can be transmitted to humans through close contact with animal species. Reservoir species acting as vectors are major traffickers of disease. Rodents contribute to the transmission of Coxiella burnetii although little is known about its prevalence in wild animal populations. ...
Lundbom J - - 2012
Upper body abdominal subcutaneous adipose tissue (SAT) can be divided into deep SAT (DSAT) and superficial SAT (SSAT) depots. Studies on adipose tissue fatty acid (FA) composition have made no distinction between these two depots. The aim of this study is to determine whether DSAT and SSAT differ in FA ...
Lu Yanhui - - 2012
Objectives: To evaluate the relationship of cognitive function with glucose tolerance status and obesity in Chinese middle-aged or aged adults. Methods: A sample of 1722 subjects aged 40 years or order was investigated from four communities in Shijingshan District, Beijing, China. People with any emotional disorder, substance abuse, known diabetes ...
Almazi Juhura G - - 2012
PURPOSE: Human Raji cells treated with fludarabine nucleoside (2-FaraA, 3 μM) undergo apoptosis with accumulation of p53 in the nuclei as multiple phosphorylated isoforms and C-terminal truncated derivatives. Changes induced by 2-FaraA in the levels of p53, p63 and p73 in the nuclear, cytosolic and mitochondrial fractions have been determined ...
Leheta Tahra M - - 2012
Abstract Background: There have been no well-controlled studies evaluating the efficacy of combining 1,540nm nonablative fractional laser with percutaneous collagen induction (PCI) and trichloroacetic acid (TCA) 20% in the treatment of atrophic acne scars. Objective: We hypothesized that combined alternating sessions of both modalities would show better results than each ...
Espino Daniel M - - 2012
A transient multi-physics model of the mitral heart valve has been developed, which allows simultaneous calculation of fluid flow and structural deformation. A recently developed contact method has been applied to enable simulation of systole (the stage when blood pressure is elevated within the heart to pump blood to the ...
Zhao Lin - - 2012
Background/Aims: To investigate the feasibility and mechanism of liver damage repair using BMSCs, we investigated the potential for BMSCs in recovery from liver damage, using the CCl4-induced rat model for liver damage. Methodology: Phenotypings of BMSCs of the third generation were analyzed by flow cytometry. BMSCs labelled by BrdU were ...
Liang Desheng - - 2012
BACKGROUND: Wolf-Hirschhorn syndrome (WHS) is caused by a deletion involving the 4p16.3 region. Approximately 70% of WHS patients have a de novo isolated deletion and 22% involve unbalanced translocations. However, WHS with unbalanced rearrangements involving the short arm of an acrocentric chromosome are infrequently reported. METHODS: Cytogenetic and molecular analyses ...
Gringeri A - - 2012
There is lack of evidence-based recommendations or clear-cut consensus regarding the clinical and economic utility of regular prophylaxis started in adulthood, with the aim of keeping the clinical situation from getting worse by prevention of further bleeds contributing to increasing musculo-skeletal or other morbidity in haemophilia. Such a prophylaxis program ...
Kobayashi Zen - - 2012
A 30-year-old Japanese woman without relevant family history presented with a behavioral abnormality followed by motor weakness about 14 years later. The patient died at age 45. Post mortem examination revealed degeneration of the frontal and temporal lobes, as well as lower motor neurons in the brainstem and spinal cord. ...
Khedri Zahra - - 2012
Sialidases or neuraminidases catalyze the hydrolysis of terminal sialic acid residues from sialyl oligosaccharides and glycoconjugates. Despite successes in developing potent inhibitors specifically against influenza virus neuraminidases, the progress in designing and synthesizing selective inhibitors against bacterial and human sialidases has been slow. Guided by sialidase substrate specificity studies and ...
Kusuma Damar Yoga - - 2012
Conductance bistability in Pt/Si-Vinylidene Fluoride (VDF) oligomer-Au ferroelectric tunnel junction devices is demonstrated. I-V and C-V measurements reveal bistable conductance switching within biasing voltage of ±0.5V with stable memory retention up to 1 × 10(4) cycles. The memory element exhibits a low switching voltage of ±1.0 V, coincides with the ...
Huang Jie - - 2012
The last few years have witnessed rapid development of biological and medical applications of graphene oxide (GO), such as drug/gene delivery, biosensing, and bioimaging. However, little is known about the cellular uptake mechanism and pathway of GO. In this work, surface-enhanced Raman scattering (SERS) spectroscopy is employed to investigate the ...
Holmberg Leif - - 2012
Rationale, aims and objectives  Evidence-based medicine and clinical guidelines have been found difficult to implement in the clinical practice - mainly because lack of evidence quality and guidelines that, generally, do not account for variations in the medical cases. Variation in the medical cases enhances task uncertainty and uncertainty seems ...
Haidarliu Sebastian - - 2012
Histochemical examination of the dorsorostral quadrant of the rat snout revealed superficial and deep muscles that are involved in whisking, sniffing, and airflow control. The part of M. nasolabialis profundus that acts as an intrinsic (follicular) muscle to facilitate protraction and translation of the vibrissae is described. An intraturbinate and ...
Forck Richard M - - 2012
The structures of sodium doped water trimers are characterized on the basis of their infrared action spectra in the OH-stretching region and a global optimization approach to identify the lowest energy minima. The most stable structure is an open ring with two contacts of terminal water molecules to the Na ...
Lee Nicole Y - - 2012
  Koebner isomorphic response describes the phenomenon of histopathologically identical skin lesions of a preceding cutaneous disease appearing in sites of trauma. Wolf isotopic response describes the phenomenon of a new skin disease appearing in the site of an unrelated cutaneous disease. Neither of the phenomena has been reported in ...
Revel F G - - 2012
Schizophrenia is a chronic, severe and highly complex mental illness. Current treatments manage the positive symptoms, yet have minimal effects on the negative and cognitive symptoms, two prominent features of the disease with critical impact on the long-term morbidity. In addition, antipsychotic treatments trigger serious side effects that precipitate treatment ...
Kırış Abdulkadir - - 2012
Objectives: Left ventricular (LV) systolic synchrony, defined as simultaneous peak contractions of corresponding cardiac segments, is well documented to be impaired in hypertension but its effect on LV function is not clear. The aim of this study was to assess the impacts of LV systolic dyssynchrony on LV function in ...
McIntosh Caroline - - 2012
The present study examines four-year-old children's everyday understandings of illness causality. Research into young children's conceptualisation of illness has led to different expectations of children's comprehension and ongoing debate regarding the nature of children's knowledge. Awareness of preschoolers' spontaneous views of illness causality, rather than explanations restricted by predetermined response ...
Shao Qian - - 2012
Protein conformation associates with particular properties of proteins and relates to protein-mediated diseases. Detailed elucidation of secondary and tertiary formation, stability, and the structural and dynamic properties of proteins has been one of the main topics studied in chemistry and biology. In this work, the conformation changes in glucose oxidase ...
Moro Sabrina - - 2012
Furan is formed in a variety of heat-treated foods through thermal degradation of natural food constituents. Relatively high levels of furan contamination are found in ground roasted coffee, instant coffee, and processed baby foods. European exposure estimates suggest that mean dietary exposure to furan may be as high as 1.23 ...
Vanlemmens Laurence - - 2012
Purpose. To determine the feelings of young women with early breast cancer concomitantly with their partners at different treatment periods in order to create a specific quality of life (QOL) scale for this population. Materiel and methods. It was a prospective, multicentre, qualitative study, in patients younger than 45 years old ...
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