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Kao Chia-Hung CH Graduate Institute of Clinical Medical Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan. - - 2012
To evaluate the relationship between the use of zolpidem and subsequent cancer risk in Taiwanese patients. We used data from the National Health Insurance system of Taiwan to investigate whether use of zolpidem was related to cancer risk. For the study cohort, we identified 14,950 patients who had received a ...
Ding Keyue K Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, - - 2012
To identify common genetic variants influencing red blood cell (RBC) traits. We performed a genomewide association study from June 2008 through July 2011 of hemoglobin, hematocrit, RBC count, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration in 12,486 patients of European ancestry from the electronic MEdical Records ...
Arnold Lesley M LM Department of Psychiatry and Behavioral Neuroscience and the Women's Health Research Program, University of Cincinnati College of Medicine, OH 45219, USA. - - 2012
Fibromyalgia is a chronic widespread pain disorder commonly associated with comorbid symptoms, including fatigue and nonrestorative sleep. As in the management of other chronic medical disorders, the approach for fibromyalgia management follows core principles of comprehensive assessment, education, goal setting, multimodal treatment including pharmacological (eg, pregabalin, duloxetine, milnacipran) and nonpharmacological ...
Arndt Carola A S CA Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN 55905, USA. - - 2012
Osteosarcoma, Ewing sarcoma, and rhabdomyosarcoma are the most common malignant musculoskeletal tumors in children and adolescents. Today, most patients can be cured. Numerous factors have contributed to improved outcome for these patients over the past several decades. These include multidisciplinary care involving oncologists, radiation oncologists, surgeons, pathologists, and radiologists and ...
Geda Yonas E YE Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ 85259, USA. - - 2012
To examine the association between computer use, physical exercise, aging, and mild cognitive impairment (MCI). The Mayo Clinic Study of Aging is a population-based study of aging and MCI in Olmsted County, Minnesota. The study sample consists of a random sample of 926 nondemented individuals aged 70 to 93 years ...
Islam Sabina A SA Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, - - 2012
Allergic inflammation develops in tissues that have large epithelial surface areas that are exposed to the environment, such as the lung, skin and gut. In the steady state, antigen-experienced memory T cells patrol these peripheral tissues to facilitate swift immune responses against invading pathogens. In at least two allergy-prone organs, ...
Larder Rachel R Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Cambridge, - - 2012
Losing weight can pose a challenge, but how to avoid putting those pounds back on can be a real struggle. A major health problem for obese people is that diseases linked to obesity, such as type 2 diabetes and cardiovascular disease, put their lives at risk, even in young individuals. ...
Holgate Stephen T ST Clinical and Experimental Sciences, Sir Henry Wellcome Laboratories, Southampton General Hospital, UK. - - 2012
The recognition that asthma is primarily an inflammatory disorder of the airways associated with T helper type 2 (T(H)2) cell-dependent promotion of IgE production and recruitment of mast cells and eosinophils has provided the rationale for disease control using inhaled corticosteroids and other anti-inflammatory drugs. As more has been discovered ...
Visram Anisa S AS School of Psychological Sciences, University of Manchester, Manchester M13 9PL, United Kingdom. - - 2012
This study investigated which acoustic cues within the speech signal are responsible for bimodal speech perception benefit. Seven cochlear implant (CI) users with usable residual hearing at low frequencies in the non-implanted ear participated. Sentence tests were performed in near-quiet (some noise on the CI side to reduce scores from ...
Cope Thomas E TE Auditory Group, Institute of Neuroscience, Newcastle University, Tyne and Wear NE1 7RU, United Kingdom. - - 2012
Previous studies investigating sensitivity to step changes in tempo and prediction of tone onset time have generally utilized isochronous sequences. This study investigates subjects' ability to detect deviations from a gradual change in the tempo of a tone sequence (experiment 1) and their judgment of the perceptually optimal timing of ...
Flemming Kate K Department of Health Sciences, The University of York, Heslington, York, United Kingdom. - - 2012
In advanced disease, the management of symptoms and lifestyle are essential for the maintenance of patients' quality of life. Appropriate education by health professionals can help patients to better manage their disease. Although the provision of education by health professionals for patients with advanced cancer is reasonably well documented, much ...
Mackenzie Alistair A National Coordinating Centre for the Physics of Mammography, Royal Surrey County Hospital, Guildford, UK. - - 2012
Undertaking observer studies to compare imaging technology using clinical radiological images is challenging due to patient variability. To achieve a significant result, a large number of patients would be required to compare cancer detection rates for different image detectors and systems. The aim of this work was to create a ...
Young Brennan J BJ Mayo Clinic, - - 2012
Investigators have identified a number of factors that increase the risk for experiencing sexual coercion, but as yet little is known about how sexual coercion in turn affects these risk factors. Using a sample of 110 adolescents, the current study examined the hypothesis that, after an incident of sexual coercion, ...
Plichta Jennifer K JK Department of Surgery, Burn and Shock Trauma Institute, Loyola University Medical Center, Maywood, Illinois 60153, - - 2012
Thousands of patients suffer from burn injuries each year, yet few therapies have been developed to accelerate the wound healing process. Most fibroblast growth factors (FGFs) have been extensively evaluated but only a few have been found to participate in the wound healing process. In particular, FGF-10 is robustly increased ...
Avanzo M M Department of Medical Physics, Centro di Riferimento Oncologico, Aviano, - - 2012
EBT2 radiochromic films were studied and used for in vivo dosimetry in targeted intraoperative radiotherapy (TARGIT), a technique in which the Intrabeam system (Carl Zeiss, Oberkochen, Germany) is used to perform intraoperative partial breast irradiation with x-rays of 50 kV(p). The energy of the radiation emitted by the Intrabeam with ...
Barreira Tiago V TV Pennington Biomedical Research Center, Baton Rouge, LA 70808-4124, - - 2012
To investigate associations between anthropometric measurements and total body fat, abdominal adipose tissue, and cardiovascular disease risk factors in a large biracial sample. This study is limited to cross-sectional analyses of data from participants attending a baseline visit between January 26, 1996, and February 1, 2011. The sample included 2037 ...
Wang Hai-Long - - 2012
The purpose of this study was to determine the effects of an extract from Moringa oleifera (MO) on the development of monocrotaline (MCT)-induced pulmonary hypertension (PH) in Wistar rats. An ethanol extraction was performed on dried MO leaves, and HPLC analysis identified niaziridin and niazirin in the extract. PH was ...
Ho Ying-Jui - - 2012
Neuroimmune system is involved in communication between the endocrine and nervous systems, which may take part in the effects of dioscorea, reversing changes of anxiety-like behavior and interleukin (IL)-2 levels in the brains of ovariectomized (OVX) rats. This study was aimed at evaluating administration of diosgenin, an ingredient of dioscorea, ...
Hanevik Hans Ivar - - 2012
Background. Assisted reproduction is traditionally regarded as effective when it results in a high pregnancy rate per started treatment cycle. For the patients, it is more interesting to know how high the probability is of giving birth during a full course of assisted reproduction treatment. Material and method. Retrospective series ...
Knechtle Beat - - 2012
Ultra-endurance performance is of increasing popularity. We investigated the associations between anthropometry, training and support during racing, with race performance in 67 male recreational ultra-endurance cyclists participating in the 'Swiss Cycling Marathon' over 600 kilometres, an official qualifier for the cycling ultra-marathon 'Paris-Brest-Paris'. The 54 finishers showed no differences in ...
Jou Yeong-Chin - - 2012
In a recent study on hepatocellular carcinoma (HCC), we have shown that the transcription factors Myeloid Zinc Finger-1 (MZF-1) and Ets-like-protein 1 (Elk-1) are significantly related to protein kinase C alpha (PKCα) expression. The purpose of this study was to determine the correlation of the expression of PKCα with the ...
Chen Kang-Hua - - 2012
Perinatal hypoxia has been observed to cause more aggressive pulmonary hypertension in human. Several mediators such as reactive oxygen species (ROS) and substance P are believed to be crucial in the mechanism of inducing pulmonary hypertension. This study was designed to test whether substance P and ROS play a role ...
Frigstad Svein-Oskar - - 2012
Anaemia may be multifactorial in origin. We present a woman with autoimmune hepatitis and secondary warm autoimmune haemolytic anaemia and most likely also concomitant anaemia of chronic disease. A relapse of autoimmune haemolysis was successfully treated with steroids and high-dose intravenous immunoglobulin. At the same time, bleeding from angiodysplasia in ...
Chen Shih-Chang - - 2012
In this study, we determined the cross-generation link between sedentary behavior of schoolchildren with their 6-year BMI progression pattern and metabolic disease category of their parents. Anthro- pometric data of 11,190 elementary schoolchildren (aged 13) were retrospectively tracked from 2003 to 2009, and classified into two groups: Normal (N = ...
Brustugun Odd Terje - - 2012
Epidermal growth-factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKI) are a relatively new class of drugs for treatment of non-small-cell lung cancer. The national professional group for lung cancer, The Norwegian Lung Cancer Group, recommends that patients with non-small-cell lung cancer are tested for mutations in the EGFR gene. Here, we ...
Roland Pål-Didrik Hoff - - 2012
Ginkgo is probably one of the most widely used medicinal herbs in Europe. In Norway products of ginkgo leaf extract have been approved by the Norwegian Medicines Agency for the following indication: traditionally used to improve blood circulation, for example, cold hands and feet. Elsewhere, ginkgo is used for cognitive ...
Rüst Christoph Alexander CA Institute of General Practice and Health Services Research, University of Zurich, Zurich, - - 2012
"The physique of Ironman triathletes was considered to be similar to that of cyclists. We intended to investigate differences and similarities in anthropometry and training between 83 Ironman triathletes competing in a qualifier for 'Ironman Hawaii' and 84 ultra-endurance cyclists competing in a qualifier for the 'Race across America'. The ...
Wang Min M Department of Geriatrics and Gastroenterology, Qi-Lu Hospital of Shandong University Key Laboratory of Proteomics of Shandong Province, Jinan Shandong, People's Republic of China. - - 2012
Our study investigated the effects of the chemopreventive agent sulforaphane (SFN) on human colon cancer Caco-2 cells and potential underlying mechanisms of the effects. When treated with SFN at hypotoxic levels, UDP-glucuronosyltransferase 1A (UGT1A) was induced in a dose-dependent manner. SFN at 25 μM showed the highest UGT1A-induction activity, inducing ...
McGurk S J - - 2012
Angular momentum depolarization and population transfer in CN(A(2)Π, v = 4, j, F(1)e) + Ar collisions have been investigated both experimentally and theoretically. Ground-state CN(X(2)Σ(+)) molecules were generated by pulsed 266-nm laser photolysis of ICN in a thermal (nominally 298 K) bath of the Ar collision partner at a range ...
Pelloni Stefano - - 2012
It is proven that, within the conventional approach using a common origin and gaugeless basis sets for the calculation of atomic magnetizability and Larmor current density induced by an external magnetic field, the natural gauge origin coincides with the nucleus. Recipes for defining an optimal gauge origin for the calculation ...
Kramer Zeb C - - 2012
The possibility of water catalysis in the vibrational overtone-induced dehydration reaction of methanediol is investigated using ab initio dynamical simulations of small methanediol-water clusters. Quantum chemistry calculations employing clusters with one or two water molecules reveal that the barrier to dehydration is lowered by over 20 kcal∕mol because of hydrogen-bonding ...
Podeszwa Rafał - - 2012
Density-functional theory (DFT) revolutionized the ability of computational quantum mechanics to describe properties of matter and is by far the most often used method. However, all the standard variants of DFT fail to predict intermolecular interaction energies. In recent years, a number of ways to go around this problem has ...
Wang Chunrui - - 2012
A converged quantum wave packet study is presented for the unimolecular reaction HOOH → OH+OH induced by the fifth OH-overtone excitation employing an ab initio potential energy surface. All six internal vibrational degrees of freedom are explicitly represented in this simulation for total angular momentum zero. It is found that ...
Pelzer Kenley M - - 2012
An open question at the forefront of modern physical sciences is what role, if any, quantum effects may play in biological sensing and energy transport mechanisms. One area of such research concerns the possibility of coherent energy transport in photosynthetic systems. Spectroscopic evidence of long-lived quantum coherence in photosynthetic light-harvesting ...
Johansson J O - - 2012
Photoelectron spectra for fullerenes C(60) and C(70) ionized using 800 nm laser pulses with pulse durations from 120 to 1000 fs show thermal electron kinetic energy distributions but they also exhibit angular anisotropy with respect to the laser light polarization. The effective temperature of electrons, measured along the laser polarization ...
Tsuduki Takayuki - - 2012
A ligand-migration mechanism of myoglobin was studied by a multidisciplinary approach that used x-ray crystallography and molecular dynamics simulation. The former revealed the structural changes of the protein along with the ligand migration, and the latter provided the statistical ensemble of protein conformations around the thermal average. We developed a ...
Piatkowski L - - 2012
We studied the vibrational energy relaxation mechanisms of the amide I and amide II modes of N-methylacetamide (NMA) monomers dissolved in bromoform using polarization-resolved femtosecond two-color vibrational spectroscopy. The results show that the excited amide I vibration transfers its excitation energy to the amide II vibration with a time constant ...
Jayasekharan T - - 2012
Rare gas containing protonated nitrogen cations, HRgN(2) (+) (Rg=He, Ar, Kr, and Xe), have been predicted using quantum computational methods. HRgN(2) (+) ions exhibit linear structure (C(∞v) symmetry) at the minima and show planar structure (C(s) symmetry) at the transition state. The stability is determined by computing the energy differences ...
Lindbo Dag - - 2012
A new method for Ewald summation in planar/slablike geometry, i.e., systems where periodicity applies in two dimensions and the last dimension is "free" (2P), is presented. We employ a spectral representation in terms of both Fourier series and integrals. This allows us to concisely derive both the 2P Ewald sum ...
Das Sanghamitra - - 2012
One generic difficulty of most state-specific many-body formalisms using the Jeziorski-Monkhorst ansatz: ψ = Σ(μ)exp(T(μ))|φ(μ)>c(μ) for the wave-operators is the large number of redundant cluster amplitudes. The number of cluster amplitudes up to a given rank is many more in number compared to the dimension of the Hilbert Space spanned ...
Whitenack Daniel L - - 2012
Aspects of density functional resonance theory (DFRT) [D. L. Whitenack and A. Wasserman, Phys. Rev. Lett. 107, 163002 (2011)], a recently developed complex-scaled version of ground-state density functional theory (DFT), are studied in detail. The asymptotic behavior of the complex density function is related to the complex resonance energy and ...
Niitsu Naoyuki - - 2012
Impulsive Raman excitation of C(60) by single or double pulses of near-infrared wavelength λ = 1800 nm was investigated by using a time-dependent adiabatic state approach combined with the density functional theory method. We confirmed that the vibrational energy stored in a Raman active mode of C(60) is maximized when ...
de Andrade M F - - 2012
We study a model of heterogeneous catalysis with competitive reactions between two monomers A and B. We assume that reactions are dependent on temperature and follow an anti-Arrhenius mechanism. In this model, a monomer A can react with a nearest neighbor monomer A or B, however, reactions between monomers of ...
Chaban Vitaly V - - 2012
We developed a new physical model to predict macroscopic properties of inorganic molten systems using a realistic description of inter-atomic interactions. Unlike the conventional approach, which tends to overestimate viscosity by several times, our systems consist of a set of ions with an admixture of neutral atoms. The neutral atom ...
Nigro B - - 2012
In conductor-insulator nanocomposites in which conducting fillers are dispersed in an insulating matrix, the electrical connectedness is established by inter-particle tunneling or hopping processes. These systems are intrinsically non-percolative and a coherent description of the functional dependence of the conductivity σ on the filler properties, and in particular of the ...
Zhang Guo-Mao - - 2012
It has been proposed that the spatial excitable media can perform a wide range of computational operations, from image processing, to path planning, to logical and arithmetic computations. The realizations in the field of chemical logical and arithmetic computations are mainly concerned with single simple logical functions in experiments. In ...
de Lara Lucas S - - 2012
We have used molecular dynamics simulations to calculate the interfacial tension of hydroxylated SiO(2) nanoparticles under different temperatures and solutions (helium and brine with monovalent and divalent salts). In order to benchmark the atomistic model, quartz SiO(2) interfacial tension was measured based on inverse gas chromatography under He atmosphere. The ...
Wojnarowska Z - - 2012
The pharmaceuticals, procaine hydrochloride and procainamide hydrochloride, are glass-forming as well as ionically conducting materials. We have made dielectric measurements at ambient and elevated pressures to characterize the dynamics of the ion conductivity relaxation in these pharmaceuticals, and calorimetric measurements for the structural relaxation. Perhaps due to their special chemical ...
Moore Stan G - - 2012
The recently developed chemical potential perturbation (CPP) method [S. G. Moore and D. R. Wheeler, J. Chem. Phys. 134, 114514 (2011)] is extended to the lattice (Ewald) sum treatment of intermolecular potentials. The CPP method predicts chemical potentials for a range of composition points using the local (position-dependent) pressure tensor ...
Felderhof B U - - 2012
The extended Navier-Stokes equations describing the steady-state hydrodynamics of a viscous fluid with spinning particles are solved for flow through a circular cylindrical tube. The flow caused by an applied torque density in the azimuthal direction and linear in the radial distance from the axis is compared with the flow ...
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