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Results 601 - 650 of 1818
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Kesieme Emeka - - 2012
Systemic air embolism is known to rarely complicate blunt chest trauma. However, cerebral infarction caused by air emboli possibly originating from a traumatic pneumatocele has not been previously reported. We report a case of a 46-year-old woman who sustained blunt chest trauma with multiple rib and clavicular fractures, hemothorax and ...
Mori Kohsuke - - 2012
Addition of O(2) enables the liquid-phase hydrogenation of phenol using H(2) at low temperatures under atmospheric pressure with an unexpected selectivity towards 2-cyclohexene-1-one rather than cyclohexanone. As a catalyst, as-synthesized Pd/MCM-41 including the residual templates within the mesoporous channels exhibits a prominent positive effect on the catalytic performance.
Fenger R - - 2012
CTAB-stabilized gold nanoparticles were synthesized by applying the seeding-growth approach in order to gain information about the size dependence of the catalytic reduction of p-nitrophenol to p-aminophenol with sodium borohydride. Five different colloidal solutions of stabilized gold nanoparticles have been characterized by TEM, AFM, UV-Vis, SAXS, and DLS for their ...
Zheng Chunhong - - 2012
We have developed an integrated microfluidic immunoassay chip for high-throughput sandwich immunoassay tests. The chip creates an array of reactive patterns through mechanical protection by actuating monolithically embedded button valves. We have demonstrated that this chip can achieve highly sensitive immunoassay tests within an hour, and requires only microliter samples.
Zheng Karen S KS Departments of Neurology and Neuroscience, Weill Cornell Medical College, New York, NY, - - 2012
Episodes of subacute worsening of motor function occur commonly in Parkinson disease (PD), but there has been surprisingly little research about the clinical characteristics of these exacerbations in the outpatient setting. Retrospective study of an established cohort of 120 outpatients with PD. Primary outcome measures were the frequency, causes, and ...
Pinckard R Neal - - 2012
In this study, numerical course scores of second-year dental students in four successive classes in an oral and maxillofacial pathology course were compared. While the course content and teaching methods were essentially unchanged throughout the four years, two modest departures from the sole use of multiple-choice format questions were made ...
Westphal Anne - - 2012
The molybdenum(V) complex [Mo(O)Cl(3)dppe] [dppe = 1,2-bis(diphenylphosphino)ethane] is considered as a model system for a combined study of the electronic structure using UV/vis absorption and magnetic circular dichroism (MCD) spectroscopy. In order to determine the signs and MCD C-term intensities of the chlorido → molybdenum charge-transfer transitions, it is necessary ...
Li Fang - - 2012
Atypical teratoid/rhabdoid tumor is a highly malignant tumor of the central nervous system, usually occurring in the posterior fossa in infants and young children. Supratentorial example is relatively rare, especially with involvement of the cerebral ventricle system. Herein, we reported 2 cases of atypical teratoid/rhabdoid tumor located in the septum ...
Rodriguez-Sosa Jose Rafael - - 2012
Testis tissue xenografting is a powerful approach for the study of testis development and spermatogenesis, and for fertility preservation in immature individuals. In bovine testis xenografts, maturation and spermatogenesis are inefficient when compared to other species. To evaluate if exogenous modulation of the endocrine milieu in recipient mice will affect ...
Hardwick Rhiannon N - - 2012
Understanding the metabolic pathway and excretion mechanisms governing the disposition of a compound is essential to the safe use of pharmaceutical agents. Because the liver is the primary organ responsible for the metabolism and elimination of xenobiotics, chronic liver disease can have a significant effect on the disposition of many ...
Koncarevic Alan - - 2012
Obesity results from disproportionately high energy intake relative to energy expenditure. Many therapeutic strategies have focused on the intake side of the equation, including pharmaceutical targeting of appetite and digestion. An alternative approach is to increase energy expenditure through physical activity or adaptive thermogenesis. A pharmacological way to increase muscle ...
Cloitre Marylène - - 2012
BACKGROUND: It has been proposed that posttraumatic stress disorder (PTSD) patients who experience significant dissociation upon exposure to traumatic reminders may do less well in trauma-focused therapies. We explored whether a sequenced two-component treatment in which an emotion regulation skills training module preceding exposure would improve outcomes for those with ...
Rykaczewski Konrad - - 2012
By promoting dropwise condensation of water, nanostructured superhydrophobic coatings have the potential to dramatically increase the heat transfer rate during this phase change process. As a consequence, these coatings may be a facile method of enhancing the efficiency of power generation and water desalination systems. However, microdroplet growth mechanism on ...
Fitzgerald Gordon - - 2012
The purposes of this study were to examine fracture risk profiles at specific bone sites, and to understand why model discrimination using clinical risk factors is generally better in hip fracture models than in models that combine hip with other bones. Using 3-year data from the GLOW study (54,229 women ...
Celli Bartolome R - - 2012
Environmental inhaled noxious particles have been known to play a role in several lung diseases, including chronic obstructive pulmonary disease (COPD) and lung cancer, the deadliest malignancy in the world in both sexes. Of the known noxious agents, tobacco smoking is the leading preventable cause of death worldwide and is ...
Wilhelm Matthieu - - 2012
Atomic-scale molecular dynamics and free energy calculations in explicit aqueous solvent are used to study the complex mechanism by which a molecule can intercalate between successive base pairs of the DNA double helix. We have analyzed the intercalation pathway for the anticancer drug daunomycin using two different methods: metadynamics and ...
Zuluaga Maria Fernanda - - 2012
ABSTRACT: Prodrugs combining macromolecular delivery systems with site-selective drug release represent a powerful strategy to increase selectivity of anticancer agents. We have adapted this strategy to develop new polymeric photosensitizer prodrugs (PPP) sensitive to urokinase-like plasminogen activator (uPA). In these compounds (to be referred to as uPA-PPPs) multiple copies of ...
Kervio Gaëlle - - 2012
Background: Scarce data are available regarding the electrocardiographic (ECG) and echocardiographic changes in athletes of Asian origin.Design: We investigate the ECG and echocardiographic patterns in Japanese (J) compared with African-Caribbean (AC) and Caucasian (C) athletes.Methods: A total of 282 professional soccer players (68 J, 96 AC and 118 C) matched ...
Li Zhijie - - 2012
PURPOSE: Activation of Akt is a marker of decreased event-free or overall survival in neuroblastoma (NB) patients. MK-2206, a novel allosteric Akt inhibitor, is now tested in clinical trials in adult cancers. In this study, effect of MK-2206 on tumor growth and murine survival, alone or in combination with etoposide ...
Jahshan Carol C Mental Illness Research, Education, and Clinical Center (MIRECC), VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA. - - 2012
Bipolar disorder and schizophrenia share common pathophysiological processes and may have similar perceptual abnormalities. Mismatch negativity (MMN) and P3a - event-related potentials associated with auditory preattentional processing - have been extensively studied in schizophrenia, but rarely in bipolar disorder. Furthermore, MMN and P3a have not been examined between diagnostic subgroups ...
Slayton Rebecca L - - 2012
In the midst of changes in the environment of academic dentistry over the past two decades, reform of traditional tenure is one way for dental schools to respond to these changes while maintaining scholarly, evidence-based learning environments. Challenges facing academic dentistry today and in the future include a crisis in ...
Ding Shu - - 2012
OBJECTIVE: To examine the role of miR-142-3p/5p in the development of autoimmunity in patients with systemic lupus erythematosus (SLE). METHODS: miRNA-142-3p/5p expression levels were determined by quantitative real-time PCR and potential target genes were tested using luciferase reporter gene assays. The effects of miR-142-3p/5p on T cell function were assessed ...
McConell Glenn K - - 2012
Nitric oxide (NO) is an important vasodilator and regulator in the cardiovascular system and this link was the subject of a Nobel prize in 1998. However, NO also plays many other regulatory roles including thrombosis, immune function, neural activity and gastrointestinal function. Low concentrations of NO are thought to have ...
Zanarini Simone - - 2012
We report the first use of cobalt aluminophosphate (CoAPO5) as a water oxidation catalyst. A decrease in the overvoltage by about 0.2 V with respect to catalyst free FTO has been observed. Additionally, we show that CoAPO5, deposited on ITO or Pt, can also act as a photo-electro-catalyst, as it ...
Eller-Vainicher Cristina - - 2012
Patients with adrenal incidentalomas (AI) and subclinical hypercortisolism (SH) have increased risk of fracture independent of bone mineral density (BMD) and possibly due to reduced bone quality. Trabecular bone score (TBS) has been proposed as a index of bone micro-architecture. The aim of the study was to investigate TBS in ...
Saeki Morihisa - - 2012
The structures of the complex of 2,2'-(methylimino)bis(N,N-dioctylacetamide) (MIDOA) with M(VII)O(4)(-) (M = Re and Tc), which were prepared by liquid-liquid solvent extraction, were investigated by using (1)H nuclear magnetic resonance (NMR), extended X-ray absorption fine structure (EXAFS), and infrared (IR) spectroscopy. The (1)H NMR spectra of the complex of MIDOA ...
Peyriere Hélène - - 2012
OBJECTIVE:To review the literature for information regarding pharmacokinetic interactions between antiretrovirals and antihypertensive agents, evaluate the clinical significance of these interactions, and analyze the effect of antihypertensive drugs on the metabolic complications frequently observed in HIV-infected patients to emphasize the advantages and inconveniences of every class of antihypertensive drugs in ...
Asahara Hiroshi - - 2012
MicroRNAs (miRs) are - 22 nucleotide non-cording forms of RNA and exhibit tissue or developmental stage specific expression patterns. Recent findings show taht the expression of miR-140, which is specifically expressed in chondrocytes, is reduced in OA chondrocytes. Furthermore, knockdown of miR-140 in mice chondrocytes promotes arthritis in mice. In ...
Fischer Elizabeth R - - 2012
Scanning electron microscopy (SEM) remains distinct in its ability to allow topographical visualization of structures. Key elements to consider for successful examination of biological specimens include appropriate preparative and imaging techniques. Chemical processing induces structural artifacts during specimen preparation, and several factors need to be considered when selecting fixation protocols ...
Yu Choongho - - 2012
The strongly-correlated thermoelectric properties have been a major hurdle for high-performance thermoelectric energy conversion. One possible approach to avoid correlation is to suppress phonon-transport by scattering at the surface of confined nanowire structures. However, phonon characteristic lengths are broad in crystalline solids, which makes nanowires insufficient to minimize heat transport. ...
Graff Joel W JW Department of Veterans Affairs, Iowa City, Iowa 52240, - - 2012
Macrophages respond to external stimuli with rapid changes in expression of many genes. Different combinations of external stimuli lead to distinct polarized activation patterns, resulting in a spectrum of possible macrophage activation phenotypes. MicroRNAs (miRNAs) are small, noncoding RNAs that can repress the expression of many target genes. We hypothesized ...
Nikoghosyan-Bossen Gohar - - 2012
The analysis of malpractice complaints can provide valuable information on patient safety. This study offers a detailed examination of the backgrounds concerning reasons and outcomes of ear, nose and throat (ENT) malpractice complaints handled by the National Board of Patients' Complaints (NBPC), 1998-2008. All NBPC decisions related to the ENT ...
Zydor Aleksandra - - 2012
It is a common finding that titanocene-derived precursors do not yield TiO(2) films in atomic layer deposition (ALD) with water. For instance, ALD with Ti(OMe)(4) and water gives 0.5 Å/cycle, while TiCp*(OMe)(3) does not show any growth (Me = CH(3), Cp* = C(5)(CH(3))(5)). From mass spectrometry we found that Ti(OMe)(4) ...
Kim Sung Hoon - - 2012
This paper presents a biologically inspired fish-robot driven by a single flexible magnetic actuator with a rotating magnetic field in a three-axis Helmholtz coil. Generally, magnetic fish-robots are powered by alternating and gradient magnetic fields, which provide a single motion such as bending the fish-robot's fins. On the other hand, ...
Peled Assaf - - 2012
ABSTRACT The ability to adapt is a fundamental and vital characteristic of the motor system. The authors altered the visual environment and focused on the ability of humans to adapt to a rotated environment in a reaching task, in the absence of continuous visual information about their hand location. Subjects ...
Depp Colin A - - 2012
Neurocognitive deficits are common in bipolar disorder and contribute to functional disability. However, the degree to which general and specific cognitive deficits affect everyday functioning in bipolar disorder is unknown. The goal of this meta-analysis was to examine the magnitude of the effect of specific neurocognitive abilities on everyday functioning ...
Terada Masahiro - - 2012
A strong organic base, TBD, functioned as a unique catalyst for the intramolecular multi-step transformation of lactols using the Ferrier-type rearrangement as the key step to provide unsymmetrically substituted 2,2'-dihydroxy biaryl compounds having four ortho substituents about the biaryl axis without the need for a metal catalyst.
Douglas de Oliveira Dhelfeson Willya - - 2012
Background: Cervical dentin hypersensitivity is characterized by tooth pain arising from root exposure. Aim: The aim of the present systematic review was to survey the literature on the efficacy of surgical root coverage techniques at reducing cervical dentin hypersensitivity in cases of gingival recession. Methods: An online electronic search was ...
Arbesman Marian - - 2012
Systematic reviews of the literature relevant to community-dwelling older adults are important to the practice of occupational therapy. We describe the four questions that served as the focus for the systematic reviews of the effectiveness of occupational therapy interventions for older adults living in the community. This article includes the ...
Pimperton Hannah - - 2012
It is well established that permanent childhood hearing impairment (PCHI) has a detrimental impact on speech and language development. The past two decades have seen the gradual introduction of universal newborn hearing screening (UNHS) programmes coupled with early intervention programmes. We review studies that have capitalised on the advent of ...
Heye Sam - - 2012
Purpose:To evaluate operator radiation exposure during percutaneous interventions on hemodialysis arteriovenous fistulas (AVFs) and arteriovenous grafts (AVGs).Materials and Methods:Seventy-seven procedures were performed in 57 patients while the interventional radiologist wore two ring dosimeters, two thermoluminescent dosimeters at the lower legs, and a thermoluminescent dosimeter on the forehead. Dose-area product, fluoroscopy ...
Champagne Benoît R - - 2012
This work demonstrates that the recognition of cations by molecular switches can give rise to large contrasts of the second-order nonlinear optical (NLO) properties, which can therefore be used as a powerful and multi-usage detection tool. The proof of concept is given by evidencing, by means of ab initio calculations, ...
Jourdain F - - 2012
The females of the moths Hylesia metabus have their abdomens covered by urticating hairs looking like micro-arrows and causing a puriginous dermatitis to humans known as "papillonite" in French Guiana and also called yellowtail moth dermatitis or Caripito itch. The densities of the moths show great seasonal and annual variations ...
Yan Jun - - 2012
Here we demonstrate a facile synthesis of homogeneous Ag nanostructures fully covering the polyaniline (PANI) membrane surface simply by introducing organic acid in the AgNO3 reaction solution, as an improved technique to fabricate well-defined Ag nanostructures on PANI substrates through direct chemical deposition method (Langmuir, 2010, 26, 8882). It is ...
Peris Tara S TS Division of Child and Adolescent Psychiatry, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90095, USA. - - 2013
Family factors such as conflict, blame, and poor cohesion have been found to attenuate response to cognitive behavior therapy (CBT) for pediatric obsessive compulsive disorder (OCD). This study examined the feasibility and acceptability of a brief, personalized intervention for cases of pediatric OCD complicated by these family features. Twenty youth ...
Duncan N - - 2012
Summary.  Prophylaxis and adherence to prophylaxis are increasingly recognized as important factors for the health-related quality of life (HRQOL) of haemophilia patients. This study aims to assess treatment practices over time, HRQOL and adherence among severe haemophilia A patients in the US. Severe haemophilia A patients or their caregivers participated ...
Schöller-Gyüre Monika - - 2012
Background: A previous study investigating coadministration of etravirine, a nonnucleoside reverse transcriptase inhibitor, and lopinavir/ritonavir soft-gel formulation resulted in nonclinically relevant changes in etravirine and lopinavir exposure. The current study evaluated the pharmacokinetic interaction between etravirine and the lopinavir/ritonavir melt extrusion formulation. Method: Sixteen human immunodeficiency virus (HIV)-negative volunteers were ...
Nanjundaiah Siddaraju M - - 2012
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by bone erosion and cartilage destruction in the joints. Many of the conventional antiarthritic drugs are effective in suppressing inflammation, but they do not offer protection against bone damage. Furthermore, the prolonged use of these drugs is associated with severe adverse ...
Ni Shaowei - - 2012
We examined the regulatory importance of interactions between regulatory light chain (RLC), essential light chain (ELC), and adjacent heavy chain (HC) in the regulatory domain of smooth muscle heavy meromyosin. After mutating the HC, RLC, and/or ELC to disrupt their predicted interactions (using scallop myosin coordinates), we measured basal ATPase, ...
Soares A L F - - 2012
Collagen provides cardiovascular tissues with the ability to withstand haemodynamic loads. A similar network is essential to obtain in tissue-engineered (TE) samples of the same nature. Yet, the mechanism of collagen orientation is not fully understood. Typically collagen remodelling is linked to mechanical loading. However, TE constructs also show an ...
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