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Results 401 - 450 of 4185
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Suthar V S - - 2012
Three experiments were conducted to determine the effect of endogenous progesterone (P4) on body temperature comparing lactating, pregnant with lactating, nonpregnant cows, and to study the effect of exogenous P4 administered via a controlled internal drug release (CIDR) insert on body temperature in lactating dairy cows. Body temperature was measured ...
Kienzler Hanna - - 2012
This article traces the social life of psychiatric practice in the context of war and postwar societies. It is argued that although psychiatric knowledge and practice is situated and grounded in particular cultural, social, and political contexts, it is important to examine how transnational networks situate local systems of meaning ...
Yuan K - - 2012
The objective of this study was to evaluate the effect of a rumen-protected niacin product (RPN; 65% nicotinic acid; NiaShure, Balchem Corp., New Hampton, NY) on lipid metabolism, oxidative stress, and performance of transition dairy cows. Thirty nonlactating multiparous Holstein cows in late gestation were paired according to expected calving ...
Eller Esben - - 2012
Large studies of individual thresholds and risk profiles for foods are sparse. Previous reports indicate that thresholds adjusted for the protein content in foods would be comparable. To establish and compare clinical threshold values for egg, hazelnut, milk and peanut, and correlating them to severity of symptoms. Seven hundred eighty-one ...
Odell John A - - 2012
The development of antituberculous drugs changed thoracic surgery and also markedly lowered the morbidity and mortality of a disease that had epidemic proportions. This article summarizes aspects from 3 important articles that led to the discovery of these drugs.
Bruschi Giuseppe - - 2012
Transcatheter valve implantation into failing surgical mitral bioprosthetic valves have been reported. This strategy avoids performing high-risk repeat cardiac surgery in elderly patients with multiple comorbidities. All these patients have been treated by a transapical approach. We report a case of failing bioprosthetic mitral valve in an 82-year-old woman successfully ...
Ali Sharif - - 2012
Context.-Patients who undergo hematopoietic stem cell transplant are at an increased risk of developing iron overload. Objectives.-To describe the effect of hepatic iron overload on hematopoietic stem cell transplant recipients and to validate the utility of histologic scoring system of iron granules in the liver. Design.-Records of 154 post allogeneic ...
Lomander H - - 2012
The objective of this field study was to evaluate the effect of supplemental feeding with glycerol or propylene glycol to dairy cows in early lactation on metabolic status, body condition and milk yield. In total, 673 newly calved cows from 12 commercial Swedish dairy herds were randomized to daily supplementation ...
Donahue M - - 2012
This study was conducted on 6 commercial dairy farms in Minnesota and Wisconsin to describe the effect of heat treatment (at 60°C for 60min) on colostrum, on colostrum bacteria counts, and immunoglobulin G concentrations. First-milking colostrum was collected each day, pooled, divided into 2 aliquots, and then 1 aliquot was ...
Wright Sasiporn - - 2012
Linagliptin (BI 1356) is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of Type 2 diabetes which recently gained approval in the US, Europe, and Japan. Linagliptin showed nonlinear pharmacokinetics after intravenous and oral administration, which is due to a concentration-dependent protein binding of linagliptin to its target enzyme DPP-4. The ...
Carter Scott L - - 2012
We describe a computational method that infers tumor purity and malignant cell ploidy directly from analysis of somatic DNA alterations. The method, named ABSOLUTE, can detect subclonal heterogeneity and somatic homozygosity, and it can calculate statistical sensitivity for detection of specific aberrations. We used ABSOLUTE to analyze exome sequencing data ...
Baer Ellen Davidson - - 2012
This article identifies some of the major ideas underpinning modern American nursing in its first 100 years, and postulates that distinct periods in nursing's early formal development were dominated by a particular theme or set of ideas. The themes, which were largely determined by social priorities, scientific advances, and national ...
Choi Hye Duck - - 2012
Cilostazol is frequently used to treat and prevent thrombosis in Korean patients. We performed the pharmacokinetic and correlation analysis of cilostazol in Korean healthy subjects. A total of male 78 volunteers was subjected to three separate bioequivalence studies in which 100 mg of cilostazol was administered. AUC, t(1/2), and C(max) ...
Lacey David L - - 2012
Bone is a complex tissue that provides mechanical support for muscles and joints, protection for vital organs, a mineral reservoir that is essential for calcium homeostasis, and the environment and niches required for haematopoiesis. The regulation of bone mass in mammals is governed by a complex interplay between bone-forming cells ...
Franke Heike - - 2012
Astrocytes are fundamental for central nervous system (CNS) physiology and are the fulcrum of neurological diseases. Astroglial cells control development of the nervous system, regulate synaptogenesis, maturation, maintenance and plasticity of synapses and are central for nervous system homeostasis. Astroglial reactions determine progression and outcome of many neuropathologies and are ...
Valle-Onate Rafael - - 2012
Physical therapy and orthopedic surgery are important components in the treatment of ankylosing spondylitis (AS). Supervised physical therapy is more effective than individual or unsupervised exercise in improving symptoms, but controlled trials suggest that combined inpatient and outpatient therapy provides the greatest improvement. Recommendations for exercise are universal, but the ...
Tse Shirley M L - - 2012
No specific recommendations for the treatment of juvenile spondyloarthritis have been established. Important differences exist in how spondyloarthritis begins and progresses in children and adults, supporting the need for pediatric-specific recommendations. Recently published recommendations for the treatment of juvenile arthritis consider children with sacroiliitis in a separate group and allow ...
Reveille John D - - 2012
Ankylosing spondylitis (AS) is associated with both significant direct and indirect costs, which vary by country, and have generally increased dramatically since the introduction of anti-tumor necrosis factor therapy. The cost-effectiveness of biologic agents is controversial, although cost-effectiveness studies need to consider the potential impact of anti-tumor necrosis factor treatments ...
Mizner Ryan L - - 2012
To determine the association of 2-dimensional (2D) video-based techniques and 3-dimensional (3D) motion analysis to assess potential knee injury risk factors during jump landing. Observational study. Research laboratory. Thirty-six female athletes in cutting and pivoting sports. : Athletes performed a drop vertical jump during which movement was recorded with a ...
Ng Kee Peng - - 2012
Cladosporium sphaerospermum is one of the most widely distributed allergens causing serious problems in patients with respiratory tract disease. We report the 26,644,473-bp draft genome sequence and gene annotation of C. sphaerospermum UM843. Analysis of the genome sequence led to the finding of genes associated with C. sphaerospermum's melanin biosynthesis, ...
Anand Mallika - - 2012
Urinary tract infections (UTIs), commonly caused by uropathogenic Escherichia coli (UPEC), confer significant morbidity among postmenopausal women. Glycosaminoglycans (GAGs) comprise the first line of defense at the bladder's luminal surface. Our objective was to use a murine model of menopause to determine whether estrogen status affects the GAG layer in ...
Russo Cesare - - 2012
Left atrial (LA) maximum volume (LAV(max)) is an indicator of left ventricular (LV) diastolic function. However, LAV(max) is also influenced by systolic events, whereas the LA minimum volume (LAV(min)) is directly exposed to LV pressure. The authors hypothesised that LAV(min) may be a better correlate of LV diastolic function than ...
Documet Patricia I - - 2012
To explore (a) how women who were diagnosed with breast cancer (BC) defined themselves as survivors and when this occurred, and (b) the types of benefits they derived from their experiences. An exploratory, qualitative approach. 112 women who had BC (response rate = 70%). Participants were recruited from two cancer ...
Jain Manu - - 2012
Multiphoton microscopy (MPM) is a nonlinear imaging approach, providing cellular and subcellular details from fresh (unprocessed) tissue by exciting intrinsic tissue emissions. With miniaturization and substantially decreased cost on the horizon, MPM is an emerging imaging technique with many potential clinical applications. To assess the imaging ability and diagnostic accuracy ...
Ng Kee Peng - - 2012
Daldinia eschscholzii is an invasive endophyte that is most commonly found in plant tissues rich in secondary metabolites. We report the draft genome sequence of D. eschscholzii isolated from blood culture. The draft genome is 35,494,957 bp in length, with 42,898,665 reads, 61,449 contigs, and a G+C content of 46.8%. ...
Wenzel Jennifer - - 2012
To obtain experiential data regarding African American older adult survivors' perceptions of and recommendations on the role of community health workers (CHWs) in providing a cancer navigation intervention. Focus groups. Rural Virginia and urban Maryland. 48 African American solid-tumor cancer survivors, aged 65 years or older, with Medicare insurance. Analysis ...
Kiyosaki Krista - - 2012
To assess the effect of initial visit with a specialist on disease understanding in women with pelvic floor disorders. Women with referrals or chief complaints suggestive of urinary incontinence or pelvic organ prolapse were recruited from an academic urology clinic. The patients completed a Test of Functional Health Literacy in ...
Kodumuri Preetham - - 2012
Septic arthritis is a life-threatening emergency with high mortality of up to 11 %. We investigated if delay of arthroscopic lavage of infected major joints would have a bearing on the mortality and morbidity such as admission to an intensive care unit (ICU). We retrospectively reviewed patients presenting with septic ...
Piantoni P - - 2012
Bovine mammary parenchyma (PAR) and fat pad (MFP) development are responsive to preweaning level of nutrient intake. We studied transcriptome alterations in PAR and MFP from Holstein heifer calves (n=6/treatment) fed different nutrient intakes from birth to ca. 65 d age. Conventional nutrient intake received 441 g of dry matter ...
- - 2012
We sought to provide evidence-based guidelines for using progestogens for the prevention of preterm birth (PTB). Relevant documents, in particular randomized trials, were identified using PubMed (US National Library of Medicine, 1983 through February 2012) publications, written in English, which evaluate the effectiveness of progestogens for prevention of PTB. Progestogens ...
Dunn Barbara K - - 2012
To define and discuss surrogate endpoint biomarkers, which are used in therapeutic trials as a substitute for the clinically meaningful "true" endpoint; and hence, may be used in answering cancer prevention questions in clinical trials evaluating drug/nutrient interventions for a number of common cancer sites. Literature, research articles. Surrogate endpoint ...
Lowry Kristin A - - 2012
To determine whether the cognitive function contribution to straight- and curved-path walking differs for older adults. Cross-sectional observational study. Ambulatory clinical research training center. People (N=106) aged 65 to 92 years, able to walk household distances independently with or without an assistive device, and who scored 24 or greater on ...
Cho En-Young Nicole EN Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstaedter Landstrasse 1, Neuherberg, - - 2012
The implantable cardioverter defibrillator (ICD) is the gold standard therapy to prevent life-threatening arrhythmias. Phobic anxiety predicts ventricular arrhythmia in coronary heart disease patients, but little is known about phobic anxiety in ICD patients. This study aimed to identify determinants and the course of phobic anxiety in ICD patients. 140 ...
Mwangi Benson B Division of Neuroscience, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK. - - 2012
Quantitative abnormalities of brain structure in patients with major depressive disorder have been reported at a group level for decades. However, these structural differences appear subtle in comparison with conventional radiologically defined abnormalities, with considerable inter-subject variability. Consequently, it has not been possible to readily identify scans from patients with ...
Picklesimer Amy H AH Department of Obstetrics and Gynecology, Greenville Hospital System University Medical Center, Greenville, SC, - - 2012
The purpose of this study was to evaluate the impact of group prenatal care on rates of preterm birth. We conducted a retrospective cohort study of 316 women in group prenatal care that was compared with 3767 women in traditional prenatal care. Women self-selected participation in group care. Risk factors ...
Lee Grace M GM Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA 02215, USA. - - 2012
In 2008, the Centers for Medicare and Medicaid Services (CMS) ceased additional payment for hospitalizations resulting in complications deemed preventable, including several health care-associated infections. We sought to understand the impact of the CMS payment policy on infection prevention efforts. A national survey of infection preventionists from a random sample ...
Culpepper Megen A MA Department of Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, - - 2012
Particulate methane monooxygenase (pMMO) is an integral membrane metalloenzyme that converts methane to methanol in methanotrophic bacteria. The enzyme consists of three subunits, pmoB, pmoA, and pmoC, organized in an α(3)β(3)γ(3) trimer. Studies of intact pMMO and a recombinant soluble fragment of the pmoB subunit (denoted as spmoB) indicate that ...
Wolleb Karin K University of Zurich, Zurich, Switzerland. - - 2012
The aim of this research was to assess survival and complication rates of tooth- and implant-supported fixed dental prostheses (FDPs) and single crowns (SCs) after 5 years of function in a specific patient population group who underwent comprehensive prosthetic treatment. This retrospective study included a convenience sample of 52 patients ...
Ziner Kim Wagler KW School of Nursing, Indiana University, Indianapolis, IN, USA. - - 2012
To determine the effect that age at diagnosis has on fear of breast cancer recurrence and to identify the predictors of fear of recurrence using self-efficacy as a mediator. Cross-sectional survey. Two university cancer centers and one cooperative group in the midwestern United States. 1,128 long-term survivors. Survivors were eligible ...
Sherman Deborah Witt DW School of Nursing, University of Maryland, Baltimore, MD, USA. - - 2012
To develop a substantive theory of the process of breast cancer survivorship. Grounded theory. A LISTSERV announcement posted on the SHARE Web site and purposeful recruitment of women known to be diagnosed and treated for breast cancer. 15 women diagnosed with early-stage breast cancer. Constant comparative analysis. Breast cancer survivorship. ...
Polovich Martha M Duke Oncology Network, Durham, NC, USA. - - 2012
To examine relationships among factors affecting nurses' use of hazardous drug (HD) safe-handling precautions, identify factors that promote or interfere with HD precaution use, and determine managers' perspectives on the use of HD safe-handling precautions. Cross-sectional, mixed methods; mailed survey to nurses who handle chemotherapy and telephone interviews with managers. ...
Loprinzi Paul D PD Department of Exercise Science, Bellarmine University, Louisville, KY, USA. - - 2012
To examine the association between physical activity and breast cancer mortality and recurrence, and to provide an overview of factors related to physical activity behavior in women with breast cancer. An extensive review of the epidemiologic literature on the effect of physical activity on breast cancer recurrence and mortality was ...
Newberry Alyssa A School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA. - - 2012
To identify changes in positive aspects of care (PAC) from the time of diagnosis to four months following the diagnosis in family caregivers of care recipients with primary malignant brain tumors. Longitudinal. Dyads were recruited from neurosurgery clinics in Pittsburgh, PA, at the time of care recipients' diagnosis with a ...
Mockler Alison A Montreal General Hospital, McGill University Health Center, Quebec, Canada. - - 2012
To better understand the experience of venous thromboembolism (VTE) from the points of view of patients with cancer during various stages of the cancer experience. Qualitative, descriptive. Various inpatient and outpatient units of a large urban university-affiliated hospital in Montreal, Quebec, Canada. Purposive sample of 10 participants who were anticipating, ...
Triolo Ronald J RJ Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106, - - 2012
To investigate the longitudinal performance of a surgically implanted neuroprosthesis for lower-extremity exercise, standing, and transfers after spinal cord injury. Case series. Research or outpatient physical therapy departments of 4 academic hospitals. Subjects (N=15) with thoracic or low cervical level spinal cord injuries who had received the 8-channel neuroprosthesis for ...
Both Leonard L Hotung Molecular Immunology Unit, Division of Clinical Sciences, St George's University of London, London, - - 2012
Prevention of clinical disease in those exposed to viral infection is an important goal of human medicine. Using rabies virus infection as an example, we discuss the advances in passive immunoprophylaxis, most notably the shift from the recommended polyclonal human or equine immunoglobulins to monoclonal antibody therapies. The first rabies-specific ...
Grebely Jason J The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia. - - 2012
Hepatitis C virus (HCV) was discovered more than two decades ago, but progress towards a vaccine has been slow. HCV infection will spontaneously clear in about 25% of people. Studies of spontaneous HCV clearance in chimpanzees and human beings have identified host and viral factors that could be important in ...
Alejo Jennifer L JL Division of Cardiac Surgery, Department of Urology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, - - 2012
Renal cell carcinoma (RCC) with cavoatrial extension is a rare and complex problem. Complete resection is difficult but correlates with favorable patient outcomes. We present 2 cases of successful reoperative resections of recurrent RCC in patients with level III-IV cavoatrial involvement. We used a thoracoabdominal approach, peripheral cannulation, and hypothermic ...
Baker-Lepain Julie C JC University of California, San Francisco, CA, - - 2012
To test whether single-nucleotide polymorphisms (SNPs) of the FRZB gene are associated with hip shape, and to determine whether FRZB variant alleles affect the relationship between hip shape and radiographic osteoarthritis (OA) of the hip. A nested case-control study of Caucasian women, age ≥65 years, from the Study of Osteoporotic ...
Miaskowski Christine C Department of Physiological Nursing, University of California, San Francisco, CA 94143-0610, USA. - - 2012
To review the evidence on a number of biomarkers that show potential clinical utility in the prediction of and treatment responsiveness for the four most common symptoms associated with cancer and its treatment (ie, pain, fatigue, sleep disturbance, depression). Review and synthesis of review articles and data-based publications. A growing ...
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