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Tachibana Masahito M Division of Reproductive and Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, Oregon, - - 2012
To demonstrate step-by-step micromanipulation procedures required for transfer of spindle-chromosomal complexes between mature oocytes. Video presentation of reproductive biology study. In vitro fertilization and embryo manipulation laboratory. Rhesus (Macaca mulatta) primates. Transplantation of the genetic material between mammalian oocytes offers many opportunities to study various aspects of nuclear-cytoplasmic interactions during ...
Petersen Bryan C BC Department of Pathology, University of Michigan, Ann Arbor, - - 2012
Interleukin-25 (IL-25) is a cytokine associated with allergy and asthma that functions to promote type 2 immune responses at mucosal epithelial surfaces and serves to protect against helminth parasitic infections in the intestinal tract. This study identifies the IL-25 receptor, IL-17RB, as a key mediator of both innate and adaptive ...
Ursell Luke K LK Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, CO, - - 2012
The human body harbors 10 to 100 trillion microbes, mainly bacteria in our gut, which greatly outnumber our own human cells. This bacterial assemblage, referred to as the human microbiota, plays a fundamental role in our well-being. Deviations from healthy microbial compositions (dysbiosis) have been linked with important human diseases, ...
Weichman Katie E KE New York University Langone Medical Center, Institute of Reconstructive Plastic Surgery, New York, NY, - - 2012
Acellular dermal matrix is commonly used in implant-based breast reconstruction to allow for quicker tissue expansion with better coverage and definition of the lower pole of the breast. This study was performed to analyze complications associated with its use in immediate two-stage, implant-based breast reconstruction and to subsequently develop guidelines ...
Bittar Sami M SM Department of Plastic and Reconstructive Surgery and Surgery, Rush University Medical Center, Chicago, IL, USA. - - 2012
Traditional latissimus dorsi myocutaneous flap breast reconstruction results in a large wound on the back, difficult inset of flap, and skin color disparity. An anterior approach to harvesting the latissimus dorsi muscle flap reduces morbidity, and with skin-sparing mastectomy, immediate single-stage reconstruction with a permanent implant is provided. A retrospective ...
Albornoz Claudia R CR Plastic and Reconstructive Surgical Service and the Center for Health Policy and Outcomes, Memorial Sloan-Kettering Cancer Center, New York, NY, - - 2012
Microsurgical breast reconstruction has gained popularity because of associations with decreased abdominal morbidity and high satisfaction. Nationwide use of these procedures is unknown. Although many factors can influence the method of breast reconstruction, sociodemographic and hospital characteristics have not been specifically evaluated. The authors studied the importance of microsurgical flaps ...
Hyun Jeong S JS Hagey Laboratory for Pediatric Regenerative Medicine, the Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford, CA, - - 2012
The phenomenon of tissue regeneration has been well documented across many species. Although some possess the capacity to completely restore an entire amputated limb, others are limited to just the distal digit tip. Initiation of limb regeneration has been described to start with the formation of a blastema, the composition ...
Quilichini Julien J Department of Plastic and Reconstructive Surgery, Henri Mondor Hospital, and the XII Medical School, Université Paris-Est Créteil, Créteil, France. - - 2012
After organ retrieval, restoration of the donor is a legal and ethical necessity; this is particularly true in facial transplantation. However, very few data are available regarding this procedure. This article reviews the seven facial masks produced during seven consecutive face transplants carried out at Henri Mondor Hospital in Paris, ...
Liu Mengyuan T MT Department of Plastic Surgery, University Hospitals Case Medical Center, Cleveland, Ohio, - - 2012
This study was designed to compare the efficacy of the transpalpebral versus endoscopic approach to decompression of the supraorbital and supratrochlear nerves in patients with frontal migraine headaches. The medical charts of 253 patients who underwent surgery for frontal migraine headaches were reviewed. These patients underwent either transpalpebral nerve decompression ...
Nayyer Leila L Center for Nanotechnology & Regenerative Medicine, UCL Division of Surgery & Interventional Science, University College London, London, United - - 2012
External ear reconstruction for congenital deformity such as microtia or following trauma remains one of the greatest challenges for reconstructive plastic surgeons. The problems faced in reconstructing the intricate ear framework are highly complex. A durable, inert material that is resistant to scar contracture is required. To date, no material, ...
Cruz Ricardo S RS Department of Plastic and Reconstructive Surgery, University of Texas Southwestern Medical Center, Rio de Janeiro, - - 2012
The cornerstone of the face lift is neck contour. The pursuit of reliable and reproducible results has led plastic surgeons to investigate a multitude of different approaches. Unfortunately, addressing neck contour can lead to complications such as injury to the great auricular nerve. The purpose of this study was to ...
Weber Robert A RA Division of Plastic Surgery, Scott & White Healthcare, 2401 South 31st Street, Temple, Texas 76508, USA. - - 2012
The purpose of this article is to introduce plastic surgeons to a theory of adult education. Most surgeons have been hired by their parent institution because of their clinical skills, and rightly so. At the same time, these same surgeons choose or are expected to be involved to varying degrees ...
Phillips Brett T BT Department of Surgery, Stony Brook University Medical Center, Health Sciences Center T19, Room 020, Stony Brook, NY 11794-8191, USA. - - 2012
Intraoperative vascular imaging can assist assessment of mastectomy skin flap perfusion to predict areas of necrosis. No head-to-head study has compared modalities such as laser-assisted indocyanine green dye angiography and fluorescein dye angiography with clinical assessment. The authors conducted a prospective clinical trial of tissue expander-implant breast reconstruction with intraoperative ...
Hassanein Aladdin H AH Department of Plastic and Oral Surgery, Children's Hospital Boston, Harvard Medical School Boston, MA, - - 2012
Cranial particulate bone graft heals inlay calvarial defects and can be harvested as early as infancy. The purpose of this study was to test the hypothesis that particulate bone promotes ossification primarily by osteogenesis. Freshly harvested particulate bone, devitalized particulate bone, and high-speed drilled bone dust from rabbit calvaria were ...
Ko Jung Min JM Department of Pediatrics, Seoul National University College of Medicine, - - 2012
Craniosynostosis is very heterogeneous in terms of its causes, presentation, and management. In particular, coronal synostosis evidences a higher tendency to be genetically caused, and TWIST1 and FGFR3 have been identified as major causative genes. The authors analyzed the clinical and molecular characteristics of Korean patients with coronal synostosis in ...
Kane Michael A C MA Lenox Hill Hospital, New York, NY, USA. - - 2012
Given the growing use of dermal fillers for cosmetic lip augmentation, a validated instrument with which to measure lip fullness is desirable in the clinic and as an efficacy endpoint in clinical studies. The authors developed and conducted a validation study of a Medicis-developed lip fullness scale. The Medicis Lip ...
Hammond Dennis C DC Partners in Plastic Surgery, Suite 202, 4070 Lake Drive, SE, Grand Rapids, MI 49546, USA. - - 2012
After studying this article, the participant should be able to: 1. Understand the preoperative considerations that must be weighed to appropriately assess operative risk of breast reduction. 2. Have a full understanding of the basic techniques that are available to treat the patient with macromastia. 3. Identify which patients are ...
Moyer Hunter R HR Division of Plastic and Reconstructive Surgery, Department of Surgery, Emory University School of Medicine, 1164 Clifton Road NE, Atlanta, GA 30322, USA. - - 2012
Preservation of breast skin during mastectomy has improved the cosmetic results of breast reconstruction. Unfortunately, the incidence of mastectomy skin flap necrosis remains high using conventional evaluation methods; therefore, accurate prediction of flap viability is an important component of postmastectomy reconstruction. The authors studied a prospective cohort of women who ...
Unger Jacob G JG Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390, - - 2012
Projection of the nasal tip is a complex problem that often mandates attention during rhinoplasty. Occasionally, the goal is to decrease tip projection. Most published solutions to this problem involve division or manipulation of the lower lateral cartilages, although objective data on the efficacy of these techniques are limited. This ...
Sears Erika Davis ED Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI, - - 2012
Outcomes measured from the patient perspective are particularly important in plastic surgery, where many of the treatments are aimed at improving physical function, psychosocial function, and quality of life. Understanding the measurement of patient-reported outcomes is critical to determine the value of the interventions performed, to better inform clinical decision-making, ...
Crosby Melissa A MA Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center. Houston, Texas 77230-1402, USA. - - 2012
As breast cancer survivorship increases, more women are being affected by treatment sequelae, including lymphedema. The purpose of this study was to evaluate lymphedema incidence among immediate breast reconstruction patients and determine what factors are associated with lymphedema, including reconstruction method. The authors reviewed the outcomes of all consecutive patients ...
Simpson S H - - 2012
We investigate the stability and thermal motion of optically trapped nanowires, with aspect ratios in the range 10-100. A simple analytical model is used to determine qualitative features of the system, assuming that the nanowire is weakly scattering and the incident beam is paraxial. As expected, the model predicts that ...
Chung Shiu-Dong - - 2012
Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? With the increased use of laparoscopic radical prostatectomy (LRP) and robot-assisted laparoscopic prostatectomy (RALP), a growing number of publications have sought to compare these more advanced techniques to retropubic RP ...
Karahan Mesut - - 2012
The water-soluble poly(methyl vinyl ether-co-maleic anhydride) copolymer-bovine serum albumin bioconjugates were synthesized in the presence of 1-ethyl-3-(3-dimetilamino-propyl) carbodiimide hydrochloride as cross-linking agents via microwave-assisted and conventional methods and characterized by size-exclusion chromatography and high-performance liquid chromatography. According to size-exclusion chromatography and high-performance liquid chromatography results, the bioconjugates synthesized in the ...
Zhang Yinzhu - - 2012
This work designs a new strategy for the direct synthesis of different zinc oxide (ZnO) nanostructures at low temperatures. Micelles of dodecylamine (DDA) assembled in an ethanol-water system have been explored as a template to direct the growth of the ZnO nanostructures. The key species for the formation of the ...
Liu Jian-Wei - - 2012
A family of water/oil interfaces is introduced to provide effective platforms for rapid fabrication of large-area self-assembled nanofilms composed of various nanosized building blocks, including nanoparticles (NPs), nanocubes (NC), nanowires (NWs), and nanosheets, at room temperature. As a general interfacial assembly method, NWs and NPs are co-assembled at the liquid/liquid ...
Yang Xuyong - - 2012
High-quality InP/ZnS core-shell nanocrystals with luminescence tunable over the entire visible spectrum have been achieved by a facile one-pot solvothermal method. These nanocrystals exhibit high quantum yields (above 60%), wide emission spectrum tunability and excellent photostability. The FWHM can be as narrow as 38 nm, which is close to that ...
Colak Ozlem - - 2012
In this study, a novel amperometric glucose biosensor was developed by immobilizing glucose oxidase (GOX) by cross-linking via glutaraldehyde on electrochemically polymerized polypyrrole-poly(vinyl sulphonate) (PPy-PVS) films on the surface of a platinum (Pt) electrode. Electropolymerization of pyrrole and poly(vinyl sulphonate) on the Pt surface was carried out with an electrochemical ...
Speed Michael P - - 2012
Defensive toxins are widely used by animals, plants and micro-organisms to deter natural enemies. An important characteristic of such defences is diversity both in the quantity of toxins and the profile of specific defensive chemicals present. Here we evaluate evolutionary and ecological explanations for the persistence of toxin diversity within ...
Huang Sheng Tian - - 2012
We report on a fast, sensitive, label-free, and general dye-sensor platform for synthetic organic dyes detection by competitive adsorption on reduced graphene oxide (rGO) against a fluorescent dye (FD). Fluorescein (Fl) as fluorescence indicator and a cationic dye methylene blue (MB) as model analyte were employed to investigate the analytical ...
Bondarenko Alexander - - 2012
High dietary Na(+) is associated with an impaired function of the vascular endothelium. The underlying mechanisms, however, are not completely understood. We investigated whether endothelial hyperpolarization induced by acetylcholine exhibits abnormalities in Wistar rats fed a high Na(+) diet (HSD) for one month, and, if so, whether chronic treatment with ...
Polac Ireneusz - - 2012
Aim:  Menopause is associated with an increased risk of cardiovascular disorders, which are accompanied by oxidative stress. Our study was undertaken to determine whether oxidative stress in menopausal women could be reduced after six months of oral or transdermal hormonal therapy. Material and Methods:  Carbonyl groups of proteins in blood ...
Vaickus Louis J - - 2012
Objectives. The aim of this study is to define the kinetics of the pulmonary inflammatory response in cockroach allergen (CRA) sensitized and challenged outbred mice. Methods. Asthma-like pulmonary inflammation was induced with three pulmonary exposures to CRA, without the use of adjuvants. Mice were sacrificed at multiple time points and ...
Uchida Sayaka - - 2012
The structural and dynamical aspects of alkylammonium salts of a silicodecatungstate [(CH(3))(4)N](4)[γ-SiW(10)O(34)(H(2)O)(2)] [], [(n-C(3)H(7))(4)N](4)[γ-SiW(10)O(34)(H(2)O)(2)] [], [(n-C(4)H(9))(4)N](4)[γ-SiW(10)O(34)(H(2)O)(2)] [], and [(n-C(5)H(11))(4)N](4)[γ-SiW(10)O(34)(H(2)O)(2)] [] were investigated. The results of sorption isotherms, XRD analyses, and solid-state NMR spectroscopy show that facile sorption of solvent molecules, flexibility of structures, and high mobility of alkylammonium cations are ...
Burugula Laxminarayana - - 2012
A simple, rapid and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) assay method has been developed and validated for simultaneous quantification of sitagliptin and simvastatin in human plasma. Carbamazepine was used as an internal standard (IS). The analytes and IS were extracted from the human plasma by liquid-liquid extraction technique. The ...
Cheng Hong-Gang - - 2012
A new class of chiral sulfoxide-Schiff base ligands has been developed by the rational combination of two privileged chiral backbones. These sulfoxide-Schiff base ligands were found to be highly efficient for Cu-catalyzed asymmetric Henry reactions (up to 98% yield and 96% ee).
Lin W - - 2012
We performed a randomised trial comparing the CEL-100 videolaryngoscope(TM) with the Macintosh laryngoscope blade in 170 patients undergoing double-lumen tube placement for thoracic surgery. Compared with the Macintosh laryngoscope blade, use of the CEL-100 resulted in significantly more patients with a Cormack and Lehane Grade-1 laryngeal view (90.4% vs 61.0%, ...
O'Brien Anthony - - 2012
Alcohol misuse is a prevalent problem in New Zealand society, and one that exacts a considerable cost in terms of health, social cohesion, and economic productivity. Despite the burden of alcohol misuse, screening, brief assessment, and interventions for alcohol problems are frequently poorly performed within general health services. In this ...
Shahrokhian Saeed - - 2012
Mixtures of gold-platinum nanoparticles (Au-PtNPs) are fabricated consecutively on a multi-walled carbon nanotubes (MWNT) coated glassy carbon electrode (GCE) by the electrodeposition method. The surface morphology and nature of the hybrid film (Au-PtNPs/MWCNT) deposited on glassy carbon electrodes is characterized by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), ...
Pedregal Concepcion - - 2012
Abstract Currently, a lack of sufficient tools has limited the understanding of the relationship between neuropsychiatric disorders and the nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor. Herein, we describe the discovery and development of an antagonist NOP receptor occupancy (RO) tracer and a novel positron emission tomography (PET) radioligand suitable to ...
Kacerovsky Marian - - 2012
Abstract OBJECTIVE: We sought to evaluate the distribution of scavenger receptor for hemoglobin positive (CD163(+)) cells in the placenta and fetal membranes from pregnancies complicated by preterm prelabor rupture of membranes with respect to the presence and absence of histological chorioamnionitis. METHODS: Sixty-two women with singleton pregnancies with a gestational ...
Park Semin - - 2012
Phospholipids (PLs) in 57 varieties of soybeans were profiled by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry and principal component analysis (PCA) to discriminate PL-rich soybeans. The PL calibration curves showed linearity with correlation coefficients >0.9964. The recoveries at 5 mg/L spiked level ranged from 72.8 to 86.7% and those at ...
Srivastava Shubhda - - 2012
Graphene-based nanocomposites have proven to be very promising materials for gas sensing applications. In this paper, we present a general approach for the preparation of graphene-WO(3) nanocomposites. Graphene-WO(3) nanocomposite thin-layer sensors were prepared by drop coating the dispersed solution onto the alumina substrate. These nanocomposites were used for the detection ...
Singh Deependra - - 2012
A biocompatible moist system was developed for effective and complete wound healing. Optimized PLGA microspheres of gentamicin (GM) and serratiopeptidase (STP) were incorporated into PVA-gelatin slurry and casted into films to prepare multiphase hydrogel. The prepared system was characterized by in vitro and in vivo studies. Results revealed the uniform ...
Singh J P - - 2012
We report a cost effective and facile way to synthesize flexible, uniform, and large area surface enhanced Raman scattering (SERS) substrates using an oblique angle deposition (OAD) technique. The flexible SERS substrates consist of 1 μm long, tilted silver nanocolumnar films deposited on flexible polydimethylsiloxane (PDMS) and polyethylene terephthalate (PET) ...
Derosa G - - 2012
Aim  To quantify how much exenatide added to metformin improves β-cell function, and to evaluate the impact on glycaemic control, insulin resistance and inflammation compared with metformin alone. Methods  A total of 174 patients with Type 2 diabetes with poor glycaemic control were instructed to take metformin for 8 ± 2 months, then ...
Cui Gang - - 2012
Flos Chrysanthemi (Gongju), a commonly used traditional Chinese medicine (TCM), has anti-inflammatory, antiviral, and anti-hypercholesterolemia properties. Its pharmacological properties are closely related to its antioxidant activity, yet its antioxidant material basis of activity is not well understood. This report describes a method developed to detect and rapidly isolate the antioxidant(s) ...
Brodskaya Elena N - - 2012
The surface layer of a direct ionic micelle with explicit solvent was simulated by the molecular dynamics method. Local properties of the system were calculated in the spherical micellar cell. The results for the local electric potential show that the contribution of a polar solvent makes the potential short-ranged, in ...
Lee Jaeho - - 2012
The coupled transport of heat and electrical current, or thermoelectric phenomena, can strongly influence the temperature distribution and figures of merit for phase-change memory (PCM). This paper simulates PCM devices with careful attention to thermoelectric transport and the resulting impact on programming current during the reset operation. The electrothermal simulations ...
Kanba Shigenobu - - 2012
Objective. To investigate the efficacy and safety of aripiprazole in Asian patients with manic or mixed episodes associated with bipolar I disorder. Methods. Subjects were randomised to aripiprazole (24 mg/day; reduced to 12 mg/day if needed for tolerability; n = 128) or placebo (n = 130) for 3 weeks in ...
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