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Knoop H - - 2012
Incidentally, a lesion in the right upper pulmonary lobe was found in a 74-year-old male patient. The flexible bronchoscopy revealed an endobrochial lipoma in the right lower lobe as the only pathological finding. Due to multiple co-morbidities, no intervention was performed initially. Since the endobronchial lipoma increased in size during ...
Sprague Matthew K - - 2012
The primary products of <italic>n</italic>-butoxy and 2-pentoxy isomerization in the presence and absence of O<sub>2</sub> have been detected using Pulsed Laser Photolysis - Cavity Ringdown Spectroscopy (PLP-CRDS). Alkoxy radicals were generated by photolysis of alkyl nitrite precursors (<italic>n</italic>-butyl nitrite or 2-pentyl nitrite), and the isomerization products were detected by infrared ...
Watanabe Masahiro - - 2012
We describe a fatal case of mumps virus-associated acute encephalopathy. In terms of the clinical course and cytokine as well as chemokine profiles, the pathogenesis in our case was different from that of mumps meningoencephalitis but was similar to that of influenza virus-associated acute encephalopathy.
Tacca Alessandra - - 2012
Anodically grown WO(3) photoelectrodes prepared in an N-methylformamide (NMF) electrolyte have been investigated with the aim of exploring the effects induced by anodization time and water concentration in the electrochemical bath on the properties of the resulting photoanodes. An n-type WO(3) semiconductor is one of the most promising photoanodes for ...
Ross B - - 2012
Background: During May and June 2011 an outbreak of enterohemorrhagic Escherichia coli (EHEC) occurred in Germany. More than 4000 patients were infected of which 800 developed hemolytic uremic syndrome (HUS) as a severe complication. Reports in the press led to great concern in the general population. Many people with diarrhea ...
Boyle Alistair - - 2012
Electrical impedance tomography (EIT) is a soft field tomography modality based on the application of electric current to a body and measurement of voltages through electrodes at the boundary. The interior conductivity is reconstructed on a discrete representation of the domain using a finite-element method (FEM) mesh and a parametrization ...
Orel Mikhail - - 2012
The Neurokinin-1 receptor (NK1R) is a G-Protein Coupled Receptor found in the central and peripheral nervous system of vertebrates, and is responsible for many physiological processes. The C-terminus domain seems to be essential for the coupling to corresponding G-protein and β-arrestin, and is important for receptor desensitization, internalization and recycling. We ...
Yang Shen-Miao - - 2012
To investigate potential predictive parameters for successful collection of autologous peripheral blood stem cells (PBSC), 60 consecutive first mobilization attempts and 145 leukapheresis procedures for patients with hematologic malignancies (multiple myeloma: n = 20; acute leukemia: n = 27; lymphoma: n = 13) were analyzed. All patients underwent chemotherapy and ...
Kim Jong Hoon - - 2012
Postoperative neck scarring is a major concern for patients who undergo thyroid surgery; however, the treatments for hypertrophic scars are generally considered by patients to provide unsatisfactory outcomes. Therefore, risk factors should be identified and prevention of these factors is considered to be critical in management. We reviewed the medical ...
Pecyna Jacek G - - 2012
The apparent ionization constants pK(a)' for series of carboxylic acids [closo-1-CB(9)H(8)-1-COOH-10-X](-) (1) and [closo-1-CB(11)H(10)-1-COOH-12-X](-) (2), where X = H, I, n-C(6)H(13), (+)NMe(3), (+)N(2), (+)SMe(2), OC(5)H(11), were measured in EtOH/H(2)O (1/1, v/v) at 24 °C. Correlation analysis of the pK(a)' values using Hammett substituent constants σ(p)(X) gave the reaction constant ρ ...
White Crh - - 2012
Please cite this paper as: White C, Doherty D, Kohan R, Newnham J, Pennell C. Evaluation of selection criteria for validating paired umbilical cord blood gas samples: an observational study. BJOG 2012; DOI: 10.1111/j.1471-0528.2012.03308.x. Objective  To compare six validation criteria for umbilical cord blood gas (UCBG) values in vigorous and ...
Qiu Xiang - - 2012
Fragment 450-650 of the spike (S) protein (S450-650) of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) contains epitopes capable of being recognized by convalescent sera of SARS patients. Vaccination of mice with recombinant S450-650 (rS450-650) can induce Abs against SARS-CoV, although the titer was relatively low. In the present study, we ...
Verendel J Johan - - 2012
Several types of chiral hetero- and carbocyclic compounds have been synthesized by using the asymmetric hydrogenation of cyclic alkenes. N,P-Ligated iridium catalysts reduced six-membered cyclic alkenes with various substituents and heterofunctionality in good to excellent enantioselectivity, whereas the reduction of five-membered cyclic alkenes was generally less selective, giving modest enantiomeric ...
Liao Hong-Jun - - 2012
Following the addition of EGF or ionomycin to A431 cells, protease activity mediates the cleavage of the EGF receptor producing a 60 kDa fragment that includes the intracellular domain (ICD). This fragment is located in both membrane and nuclear fractions. Based on sensitivity to chemical inhibitors and overexpression of cDNAs, ...
Lönnroos Eija - - 2012
Background: Medications with anticholinergic and sedative effects carry significant risks in older people. Adverse events arising from the use of these medications may also lead to hospitalization and contribute to length of stay. The Drug Burden Index (DBI) is a tool that measures a person's total exposure to medications with ...
Wang W - - 2012
Divalproex sodium is an antiepileptic drug. Hepatotoxicity is one of the most common side effects induced by divalproex sodium. Impaired fatty acid metabolism is considered to play an important role in the drug-induced hepatotoxicity. The sterol regulatory element-binding protein 1c (SREBP-1c) and peroxisome proliferator-activated receptor α (PPARα) are two key ...
Hayrabedyan Soren - - 2012
It is currently accepted that the Sertoli cells are proliferatively active only during the embryogenesis and early fetal development, seizing to divide after puberty, when the spermatogenic niche is prepared, and they become terminally differentiated. So far, only seasonal breeders from mammals have been reported as having season-dependent variations in ...
Mahar Kelly M - - 2012
To further characterize the time course of gastric pH with respect to meals and gastric residence times (GRTs) in dogs, continuous pH measurements were recorded with Bravo® capsules, which were attached to the dogs' stomach mucosa or administered as free capsules, respectively. Experiments took place in home or study cages, ...
Ding Caifeng - - 2012
Herein we report a polymerase chain reaction (PCR)-free electrochemiluminescence (ECL) approach that uses ECL nanoprobes for the determination of cancer cells with high sensitivity. The ECL nanoprobe consists of gold nanoparticles (AuNPs), linker DNA, and tris(2,2'-bipyridyl)ruthenium (TBR)-labeled signal DNA. The linker DNA and signal DNA were modified on the surface ...
Coulter Cynthia - - 2012
This paper describes the determination of tetrahydrocannabinol (THC) and its metabolite, 11-nor-Δ(9)-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) in oral fluid using solid-phase extraction and liquid chromatography with tandem mass spectral detection (LC-MS-MS) and its application to proficiency specimens. The method employs collection of oral fluid with the Quantisal™ device, base hydrolysis, solid-phase extraction ...
Wu Kuan-Lin - - 2012
Panchromatic Os(II) sensitizers for dye-sensitized solar cells (DSCs) were prepared. A DSC based on TF-52 showed promising performance characteristics: short-circuit photocurrent density J(SC) =23.3 mA cm(-2) , open-circuit photovoltage V(OC) =600 mV, fill factor (FF)=0.633 and power conversion efficiency η=8.85 % under AM 1.5G simulated one-sun irradiation.
Liao Kristine - - 2012
The coverage dependent heats of adsorption and sticking probabilities for oxygen on fcc Co{110} have been measured at 300 K using single crystal adsorption calorimetry (SCAC). Initial adsorption is consistent with dissociative chemisorption at low coverage followed by oxide formation above 0.6 ML coverage. The initial heat of adsorption of ...
Neilson James Richmond - - 2012
Here, we study the nature of metal--metal bonding in the ThCr<sub>2</sub>Si<sub>2</sub> structure type by probing the rate-limiting steps in the oxidative deintercalation of KNi<sub>2</sub>Se<sub>2</sub>. For low extents of oxidation, alkali ions are removed exclusively to form K<sub>1-<italic>x</italic></sub>Ni<sub>2</sub>Se<sub>2</sub>. For greater extents of oxidation, the rate of the reaction decreases dramatically, concomitant ...
Espuña-Pons Montserrat - - 2012
AIMS: To estimate the frequency of double incontinence, and to identify associated risk factors during pregnancy and postpartum in previously continent nulliparous women. METHODS: A cohort study in healthy, nulliparous, continent pregnant women, attending the public healthcare system of Catalonia (Spain) was designed. The field work was conducted during the ...
Goodman Karyn A - - 2012
Local failure remains a major issue for patients with both resectable and locally advanced pancreatic cancer. The role of radiation therapy in the management of this disease is less clear and represents an area of some controversy. The objective of this review is to present the rationale for radiation therapy ...
Ramasamy Karthik - - 2012
Power generation through photovoltaics (PV) has been growing at an average rate of 40% per year over the last decade; but has largely been fuelled by conventional Si-based technologies. Such cells involve expensive processing and many alternatives use either toxic, less-abundant and or expensive elements. Kesterite Cu(2)ZnSnS(4) (CZTS) has been ...
Rizell Sara - - 2012
The aim of this project was to study the impact on craniofacial morphology from Turner syndrome (TS) karyotype, number of intact X chromosomal p-arms, and age as well as to compare craniofacial morphology in TS with healthy females. Lateral radiographs from 108 females with TS, ranging from 5.4 to 61.6 ...
Fritz Heidi - - 2012
Background: Green tea is a beverage widely used by lung cancer patients and the public for its purported anticancer properties. The authors conducted a systematic review of green tea for the treatment and prevention of lung cancer. Methodology: Six electronic databases were searched from inception until November 2011 for human ...
Blümel J E - - 2012
Objective Few Latin American studies have described menopausal symptoms in detail by means of a standardized assessment tool. The objective of this study was to assess the prevalence and severity of menopausal symptoms and their impact over quality of life among mid-aged Latin American women. Method In this cross-sectional study, ...
Morellini Natalie M - - 2012
Burn injury can lead to abnormal sensory function at both the injury and at distant uninjured sites. Here, we used a mouse model to investigate return of nociceptive function and reinnervation of the skin at the wound and uninjured distant sites following a 3% total burn surface area full-thickness burn ...
Pernet Adeline - - 2012
Background. Patient safety during radiotherapy has become a central priority for public policy further to the various accidents arisen at Epinal, Toulouse and Grenoble for the most symbolic. In this context, patients' involvement in the management of their own safety can be a way to improve the quality of care ...
Dieckmann Michael - - 2012
Symmetry helps: The total synthesis of the potent actin-targeting C(2) -symmetric myxobacterial macrolide rhizopodin is accomplished by the convergent assembly of three building blocks of similar complexity, a concise macrocyclization strategy, and a late-stage introduction of the labile side chains.
Chiu Hei Yeung - - 2012
Body donation is important for medical education and academic research. However, it is relatively rare in Hong Kong when compared with many Western countries. Comprehensive research has been performed on the motivation for body donation in Western countries; however, there is still insufficient research on body donation in Hong Kong ...
Fan M-J - - 2012
Safrole, a component of piper betle inflorescence, is a documented rodent hepatocarcinogen and inhibits bactericidal activity and the release of superoxide anion (O(2-)) by polymorphonuclear leukocytes (PMNs). In the present study, we investigated the effects of safrole on immune responses, including natural killer (NK) cell cytotoxicity, phagocytic activity and population ...
Bar-Ziv Ronen - - 2012
Methyl radicals react with Pt(0) NPs suspended in aqueous solutions in fast reactions. The major product is stable methyl coated Pt(0) NPs, (Pt(0) NPs)(CH(3) )(n) . C(2) H(6) , C(2) H(4) and some polymerization products are also formed.
Shikata Toshiyuki - - 2012
The dielectric behaviors of some small symmetric ketone molecules, including acetone, 3-pentanone, cyclopentanone, 4-heptanone and cyclohexanone, were investigated as a function of temperature (T) over a wide frequency range from 50 MHz (3.14 × 10<sup>8</sup> s<sup>-1</sup>, in angular frequency) to 3 THz (1.88 × 10<sup>13</sup> s<sup>-1</sup>). The temperature dependencies of ...
Lan F - - 2012
BACKGROUND AND OBJECTIVE: Transcutaneous electrical nerve stimulation (TENS) is regarded as an effective treatment for various types of pain. However, no randomized controlled trial has investigated TENS on acupoints for postoperative analgesia in elderly patients. This study aim to investigate whether TENS on acupoints has any favorable effect on complementary ...
Wang Bin - - 2012
Bioinspired manganese complexes based on N(4) ligands, with a more rigid, chiral diamine derived from proline and two benzimidazoles, were synthesized and applied to epoxidize olefins with hydrogen peroxide as a clean oxidant. Notably, 60-99 % isolated yields and excellent ee values (up to 95 %) were obtained by using low catalyst ...
Denis Pablo A - - 2012
The interaction between alkyl radicals and graphene was studied by means of dispersion-corrected density functional theory. The results indicate that isolated alkyl radicals are not likely to be attached onto perfect graphene. It was found that the covalent binding energies are low, and because of the large entropic contribution, Δ${G{{{\standard}\hfill ...
Plisson Fabien - - 2012
Screening a library of Southern Australian and Antarctic marine invertebrates and algae for inhibitors of neurodegenerative disease kinase targets casein kinase 1 (CK1δ), cyclin-dependent kinase 5 (CDK5) and glycogen synthase kinase 3β (GSK3β) identified a Western Australian Didemnum species (CMB-02127) as a high-priority specimen. Chemical fractionation returned the known aromatic alkaloids ningalins B-D ...
Khanfar M - - 2012
Abstract Context: Liquisolid technique is one of the methods used to improve the dissolution rate of the poorly water soluble drugs utilizing non volatile liquids.Objectives: Enhancement of the release of ezetimibe from different liquisolid formulations.Materials and Methods: Four liquid vehicles were used to prepare the liquid medications with different drug ...
Zucchi Eliana V M - - 2012
OBJECTIVE: To evaluate the expression of nerve growth factor (NGF) in the urethra of adult female rats in different hormonal status using immunohistochemical assay. METHODS: Forty-eight rats (Rattus norvegicus albinus, Rodentia, Mammalia) from the CEDEME-UNIFESP laboratory animal facility were used in the study. Rats were divided into four groups: group ...
Davies Stephen G - - 2012
"Matching" and "mismatching" effects in the doubly diastereoselective conjugate additions of the antipodes of lithium N-benzyl-(N-α-methylbenzyl)amide to enantiopure cis- and trans-dioxolane containing α,β-unsaturated esters have been investigated. High levels of substrate control were established first upon conjugate addition of achiral lithium N-benzyl-N-isopropylamide to both tert-butyl (S,S,E)-4,5-O-isopropylidene-4,5-dihydroxyhex-2-enoate and tert-butyl (4R,5S,E)-4,5-O-isopropylidene-4,5-dihydroxyhex-2-enoate. However, ...
Long Jennifer - - 2012
Background:  Work-related physical discomfort exists within the optometric profession. It is not well understood how optometrists manage this issue in their workplaces. Method:  An online questionnaire was sent by e-mail to approximately 1,700 Australian optometrists. Participants were asked if they experienced work-related discomfort in any of eight nominated body regions. ...
Kato Jason - - 2012
Vincristine (VCR) is a potent anti-cancer drug but its clinical efficacy is limited by neurotoxicity. The field of drug delivery may provide an opportunity to increase the therapeutic index of VCR by delivering the drug specifically to tumor sites while sparing normal tissue. We have recently developed a telodendrimer (PEG5k-Cys4-L8-CA8) ...
de Faria Emerson H - - 2012
The catalytic efficiency of takovite-aluminosilicate-chromium catalysts obtained by adsorption of Cr3+ ions from aqueous solutions by a takovite-aluminosilicate nanocomposite adsorbent is reported. The adsorbent was synthesized by the co-precipitation method. The catalytic activity of the final Cr-catalysts depended on the amount of adsorbed chromium. (Z)-cyclooctene conversion up to 90% with ...
Amonn Kathrin - - 2012
OBJECTIVES: To compare health-related quality of life (QoL) in patients undergoing transcatheter aortic valve implantation via transapical access (TA TAVI) with patients undergoing surgical aortic valve replacement (SAVR). METHODS: One hundred and forty-four high-risk patients referred for aortic valve replacement underwent TAVI screening and were assigned to either TA TAVI ...
Iwahori Kota - - 2012
Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis for which an effective therapy remains to be established. This study investigated the therapeutic potential of gene delivery using suppressor of cytokine signaling 1 (SOCS-1), an endogenous inhibitor of intracellular signaling pathways, for the treatment of MPM. We infected ...
Je Eun Mi - - 2012
Recurrent somatic mutations in MED12 exon 2 have recently been reported in uterine leiomyomas. The recurrent nature of the mutations strongly suggests that the mutations may play important roles in the pathogenesis of uterine leiomyomas. The aim of this study was to see whether MED12 exon 2 mutations occur in ...
Simons Claudia J P - - 2012
Psychotic disorders are associated with neurocognitive alterations that aggregate in unaffected family members, suggesting that genetic vulnerability to psychotic disorder impacts neurocognition. The aim of the present study was to investigate whether selected schizophrenia candidate single nucleotide polymorphisms (SNPs) are associated with (1) neurocognitive functioning across populations at different genetic ...
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