Search Results
Results 401 - 450 of 3890
< 4 5 6 7 8 9 10 11 12 13 14 >
Ma Weiya - - 2012
Neuropathic pain (NeP) is an intractable chronic pain condition which severely deteriorates the quality of life of 6% of the population. Caused by direct physical damage or diseases of the nervous system responsible for pain generation and transmission, NeP is manifested as spontaneous pain, hyperalgesia and allodynia. Its treatment is ...
Poulsen Mads H - - 2012
Study Type - Diagnostic (exploratory cohort) Level of Evidence 2a What's known on the subject? and What does the study add? Staging of patients with prostate cancer is the cornerstone of treatment. However, after curative intended therapy a high portion of patients relapse with local and/or distant recurrence. Therefore, one may ...
Kawai Yoshihisa - - 2012
What's known on the subject? and What does the study add? Ras association domain family 1A (RASSF1A) is a tumour suppressor and regulates cell cycle, apoptosis and microtubule stability. This is the first study to identify associations between RASSF1A polymorphisms and clinicopathological parameters and survival in patients with clear cell ...
Bhatta Raghavendra - - 2012
BACKGROUND: Plant tannins as rumen modifiers are better than chemicals or antibiotic-based modifiers since these compounds are natural products which are environmentally friendly and therefore have a better acceptance with regard to feed safety issues. Tropical plants containing phenols such as tannins were found to suppress or eliminate protozoa from ...
Fischer Steven L - - 2012
The use of principal component analysis (PCA) as a multivariate statistical approach to reduce complex biomechanical data-sets is growing. With its increased application in biomechanics, there has been a concurrent divergence in the use of criteria to determine how much the data is reduced (i.e. how many principal factors are ...
Fine Kari L - - 2012
Interactions between Mycobacterium tuberculosis bacilli and alveolar macrophages have been extensively characterized, while similar analyses in epithelial cells have not been performed. In this study, we microscopically examined endosomal trafficking of M. tuberculosis strain Erdman in A549 cells, a human type II pneumocyte cell line. Immuno-electron microscopic (IEM) analyses indicate ...
Ayres Karen - - 2013
Measuring intentions and other cognitions to perform a behaviour can promote performance of that behaviour (the question-behaviour effect, QBE). It has been suggested that this effect may be amplified for individuals motivated to perform the behaviour. The present research tested the efficacy of combining a motivational intervention (providing personal risk ...
Mizoguchi Haruki - - 2012
We have developed a unique catalytic protocol for direct gem-vinylation of tryptamine derivatives employing Hg(OTf)(2) as the optimum catalyst. The intermolecular vinylations with a series of aromatic acetylenes proceeded under ambient temperature at the C2 positions of indoles with high functional group tolerance. Based on the mechanistic insights, we further ...
Nagata K - - 2012
A retrospective evaluation of 232 feline nasal biopsies initially diagnosed as either carcinoma or lymphoma was performed by two pathologists. One or both pathologists disagreed with the original diagnosis in 15 cases (7%), 14 of which had original diagnoses of carcinoma. Out of the 232 cases, 140, including the disputed ...
Ablinger Irene - - 2012
Although changes in reading performance of recovering letter-by-letter readers have been described in some detail, no prior research has provided an in-depth analysis of the underlying adaptive word processing strategies. Our work examined the reading performance of a letter-by-letter reader, FH, over a period of 15 months, using eye movement ...
Chang Hubert - - 2012
Abstract Background. A multicomponent evaluation of the oxidative consumption of salivary biomolecules by a tooth-whitening oral rinse preparation has been performed using high-resolution proton ((1)H) nuclear magnetic resonance spectroscopy (NMR). Methods. Unstimulated human saliva samples (n = 12) were treated with aliquots of the oral rinse tested and 600 MHz ...
Kaneko Yoko S - - 2012
We previously reported that the optimal dose of lipopolysaccharide markedly extends the life span of mouse primary-cultured microglia by suppressing apoptotic and autophagic cell death pathways. This study was undertaken to assess how these cells protect themselves against reactive oxygen species generated by lipopolysaccharide treatment. We used microglia obtained from ...
Lorente Nicolas - - 2012
Abstract In low- and middle-income countries, men who have sex with men (MSM) are 19 times more likely to be HIV positive compared with background populations. Criminalisation and social rejection of homosexuality in most sub-Saharan African countries reinforce stigma and exclude MSM from prevention activities, including HIV testing. This paper's ...
Komatsu Shuhei S Kyoto Prefectural University of Medicine, Division of Digestive Surgery, Department of Surgery, 465 Kajii-cho, Kawaramachihirokoji, Kamigyo-ku, Kyoto 602-8566, Japan. - - 2012
miR-21 and miR-375 are reported to be highly and poorly expressed in esophageal squamous cell carcinoma (ESCC) tissues, respectively. Recently, we demonstrated that circulating miR-21 and miR-375 were stably detectable in plasma and reflected tumor dynamics as a tumor marker for ESCC. We hypothesized that these plasma miRNA concentrations contributed ...
Monti Jim M JM Department of Psychology, University of Illinois at Urbana-Champaign, IL, USA. - - 2012
It is widely accepted that aerobic exercise enhances hippocampal plasticity. Often, this plasticity co-occurs with gains in hippocampal-dependent memory. Cross-sectional work investigating this relationship in preadolescent children has found behavioral differences in higher versus lower aerobically fit participants for tasks measuring relational memory, which is known to be critically tied ...
Mamot Christoph - - 2012
Abstract Immunoliposomes (ILs) can be constructed to target the epidermal growth factor receptor (EGFR) to provide efficient intracellular drug delivery in tumor cells. We hypothesized that this approach might be able to overcome drug resistance mechanisms, which remain an important obstacle to better outcomes in cancer therapy. ILs were evaluated ...
Wada Atsushi - - 2012
Efficient luminescence was realized by suppressing not only excited-state distortion but also C-H vibrational quenching in a Cu complex. Organic light-emitting diodes containing the Cu complex as an emitting dopant exhibited a maximum external quantum efficiency of 7.4%.
Hunter Corey - - 2012
Chronic pelvic pain (CPP) is complex and often resistant to treatment. While the exact pathophysiology is unknown, the pain states resultant from conditions such as interstitial cystitis and the like yield patients with a presentation that bears a striking similarity to neuropathic syndromes that are known to respond to neuromodulation. ...
Abe Koichiro - - 2012
Sickle tail (Skt) was originally identified by gene trap mutagenesis in mice, and the trapped gene is highly expressed in the notochord, intervertebral discs (IVD), and mesonephros. Here we report the generation of Skt(cre) mice expressing Cre recombinase in the IVD due to target insertion of the cre gene into ...
Silberman Daniel D Department of Biology, Rider University, Lawrenceville, NJ 08648, - - 2012
When compared to spleen or lymph node cells, resident peritoneal cavity cells respond poorly to T-cell activation in vitro. The greater proportional representation of macrophages in this cell source has been shown to actively suppress the T-cell response. Peritoneal macrophages exhibit an immature phenotype (MHC class II(lo), B7(lo)) that reduces ...
Rodrigues F S L M - - 2012
Accurate lineage tracing is crucial to understanding of developmental and stem cell biology, but is particularly challenging for transient and highly dispersive cell-types like the neural crest (NC). We report here a new zebrafish transgenic line Tg(-4725sox10:Cre)(ba74) . This line expresses Cre under the control of a well-characterised portion of ...
Fields David A - - 2012
Body composition assessment during infancy is important because it is a critical period for obesity risk development, thus valid tools are needed to accurately, precisely, and quickly determine both fat and fat-free mass.The purpose of this study was to compare body composition estimates using dual-energy x-ray absorptiometry (DXA) and air ...
Yeung Ching-Hei - - 2012
Epididymal tumour incidence is at most 0.03% of all male cancers. It is an enigma why the human epididymis does not often succumb to cancer, when it expresses markers of stem and cancer cells, and constitutively expresses oncogenes, pro-proliferative and pro-angiogenic factors that allow tumour cells to escape immunosurveillance in ...
Zhou Erjun - - 2012
A new alternating copolymer of fluorene and naphthalene diimide, PF-NDI, was synthesized and characterized. The highest power conversion efficiency of all-polymer solar cells based on P3HT:PF-NDI reached 1.63% with a relatively high fill factor of 0.66 by using 1,8-diiodooctane as a solvent additive to optimize the mixing morphology.
Sipponen Taina - - 2012
Abstract Objective. Data on fecal calprotectin and S100A12 in predicting wireless capsule endoscopy (WCE) findings in suspicion of Crohn's disease (CD) are scarce. Our aim was to study the role of calprotectin and S100A12 in predicting inflammatory lesions of small bowel in patients undergoing WCE. Material and methods. 84 patients ...
Chitrapriya Nataraj - - 2012
The photo-induced cleavage of pGEM-7zf-NIS super-coiled DNA by Cu(ii)-meso-tetrakis(n-N-methylpyridiniumyl)porphyrins (n = 2, 3, 4 referred to as o-, m- and p-CuTMPyP, respectively) and their binding mode were investigated in this study. m-CuTMPyP was most efficient in cleavage than o- and p-CuTMPyP isomers. Cleavage was suppressed by N(2) bubbling, suggesting that ...
Ota Y - - 2012
OTA Y., MORITO A., FUJISAWA K., NISHIDA M., HATA H., UENO T., YURIKUSA T. & MURATA T. (2012) European Journal of Cancer Care Evaluation of a moisturising micro-gel spray for prevention of cell dryness in oral mucosal cells: an in vitro study and evaluation in a clinical setting A moisturising ...
Guo Wenxi - - 2012
We present a new approach to fabricate an integrated power pack by hybridizing an energy harvest and storage processes. This power pack incorporates dye-sensitized solar cell (DSSC) and lithium ion battery (LIB) on the same Ti foil that has double-sided TiO2 nanotube (NTs) arrays. The solar cell part is made ...
Gwathmey Kelly - - 2012
Neurologists commonly use therapeutic plasma exchange (TPE) to treat a number of conditions. This concise review examines the most common neurologic indications for TPE. It focuses on Guillain-Barre' syndrome and myasthenia gravis and also the role of TPE in chronic inflammatory demyelinating polyneuropathy, Lambert-Eaton syndrome, multiple sclerosis, neuromyelitis optica, paraproteinemic ...
Nishino Taito - - 2012
Hematopoietic stem cells (HSCs) are defined by their capacity to self-renew and to differentiate into all blood cell lineages, and are currently the foundation of HSC transplantation therapy. A variety of methods have recently been explored to find a way to expand hematopoietic stem and progenitor cells (HSCs/PCs) ex vivo ...
Na H S - - 2012
We investigated the effects of magnesium sulphate on blood coagulation profiles using rotational thromboelastometry in gynaecological patients undergoing pelviscopic surgery. Patients were randomly allocated to the magnesium group (n = 20) or control group (n = 20). The magnesium group received magnesium sulphate (50 mg.kg(-1) followed by continuous infusion of 15 mg.kg(-1) .h(-1) ), whereas the ...
Wu T - - 2012
Aim  Corneal confocal microscopy is a promising screening method for diabetic neuropathy. Although much research in this field has been accomplished, we aimed to determine and confirm the known clinical and eyewear variables associated with the parameters of corneal confocal microscopy specifically in healthy volunteers, in particular associations with corneal ...
Goiato Marcelo C - - 2012
doi: 10.1111/j.1741-2358.2012.00676.x Effect of thermal cycling and disinfection on colour stability of denture base acrylic resin Objectives:  The purpose of this study was to investigate the effect of thermal cycling and disinfection on the colour change of denture base acrylic resin. Materials and Methods:  Four different brands of acrylic resins ...
Liu Huijun - - 2012
Abstract China has experienced continual increase in the sex ratio at birth (SRB) since the 1980s, which has led to a serious gender imbalance. To identify whether the future forced bachelors, especially those who migrate to cities, will increase the risk of HIV spread, a systematic review was carried out ...
Kolotkin Ronette L - - 2012
We review the literature on the relationship between obesity and sexual functioning. Eleven population-basedstudies, 20 cross-sectional non-population-based studies,and16weight loss studies are reviewed.The consistency of findings suggests that the relationship between obesity and reduced sexual functioning is robust, despite diverse methods, instruments, and settings.In most population-based studies, erectile dysfunction (ED) is ...
Srisuwan Tanida - - 2012
Abstract -  Background:  Regenerative endodontics is an innovative treatment concept aiming to regenerate pulp, dentin and root structures. In the diseased or necrotic tooth, the limitation in vascular supply renders successful tissue regeneration/generation in a whole tooth challenging. The aim of this study is to evaluate the ability of vascularized tissue ...
Roberts M - - 2012
ACCESSIBLE SUMMARY: •  The manner in which the arts can contribute and enhance the practical, therapeutic concerns of mental health professionals is becoming well established in the health care literature. •  The aesthetic theory of the Hungarian philosopher Georg Lukács and, in particular, his concept of specific particularity presents the ...
Evjenth Bjørg - - 2012
Introduction:  Exhaled nitric oxide (FE(NO) ) measurements are recommended to be performed before spirometry and exercise challenge tests because forced breathing might influence FE(NO ) values. Information on the effect of exercise on FE(NO) is lacking in non-asthmatic children. Aim:   To investigate the effect on FE(NO) of a standardized ...
Giordano Cristina - - 2012
Purpose  To describe a case of a cat with primary B-cell lymphoma affecting the eye and brain and which shared features similar to oculo-cerebral lymphoma in humans. Methods  A 13-year-old castrated male Persian cat presented with clinical signs of anterior uveitis and increased intraocular pressure (IOP) in the left eye ...
Vermeij Wilbert P - - 2012
Protection against injurious external insults and loss of vital fluids is essential for life and is in all organisms, from bacteria to plants and humans, provided by some form of barrier. Members of the small-proline-rich (SPRR) protein family are major components of the cornified cell envelope (CE), a structure responsible ...
Tanno L K LK Emergency Department, Hospital Sírio Libanês, São Paulo, Brazil. - - 2012
Undernotification is well recognized as a key challenge to the study of anaphylaxis mortality, but it is seldom mentioned that one of its reasons is the difficult coding of the condition under the tenth revision of the international classification of diseases (ICD-10), given that there are no anaphylaxis-specific ICD-10, which ...
Chareyron Loïc J - - 2012
The amygdala is the central component of a functional brain system regulating fear and emotional behaviors. Studies of the ontogeny of fear behaviors reveal the emergence of distinct fear responses at different postnatal ages. Here, we performed a stereological analysis of the rat amygdala to characterize the cellular changes underlying ...
Eskew Evan A - - 2012
The natural flow regimes of rivers worldwide have been heavily altered through anthropogenic activities, and dams in particular have a pervasive effect on riverine ecosystems. Flow-regulation effects of dams negatively affect species diversity and abundance of a variety of aquatic animals, including invertebrates and fishes. However, the effects on semiaquatic ...
Debes Paul V - - 2012
Escaped domesticated individuals can introduce disadvantageous traits into wild populations due to both adaptive differences between population ancestors and human-induced changes during domestication. In contrast to their domesticated counterparts, some endangered wild Atlantic salmon populations encounter during their marine stage large amounts of suspended sediments, which may act as a ...
Ferranti F - - 2012
The glial cell line-derived neurotrophic factor (GDNF) has multiple functions that promote cell survival, proliferation and migration in different cell types. The experimental over-expression of GDNF in mouse testis leads to infertility and promotes seminomatous germ cell tumours in older animals, which suggests that deregulation of the GDNF pathway may ...
Liu Shuang - - 2012
In managing invasions and colonizations of non-native species, eradication or control efforts must proceed quickly. There are 2 challenges in taking such quick action. First, managers frequently have to choose among complex and often competing environmental, social, and economic objectives. Second, the effects are highly uncertain. We applied participatory structured ...
Marelli Marco - - 2012
The present study employs neglect dyslexia (ND) as an experimental model to study compound-word processing; in particular, it investigates whether compound constituents are hierarchically organized at mental level and addresses the possibility of whole-word representation. Seven Italian-speaking patients suffering from ND participated in a word naming task. Both left-headed (pescespada, ...
Harding Richard - - 2012
Abstract Patient self-reported outcomes are increasingly important in measuring disease, treatment and care outcomes. It is unclear what constitutes well-being using a combined biomedical and psychosocial approach for patients with antiretroviral therapy (ART) access. This study aimed to determine the variance within the visual analogue scale (VAS) measure of health ...
Bornas Xavier - - 2012
The cognitive regulation of emotions is important for human adaptation. Self-focused emotion regulation (ER) strategies have been linked to the development and persistence of anxiety and depression. A vast array of research has provided valuable knowledge about the neural correlates of the use of specific self-focused ER strategies; however, the ...
Fløisand Y - - 2012
Reduced-intensity conditioning (RIC) allo-SCT is a potentially curative treatment approach for patients with relapsed Hodgkin's or non-Hodgkin's lymphoma. In the present study, 37 patients underwent RIC allo-SCT after induction treatment with EPOCH-F(R) using a novel form of dual-agent immunosuppression for GVHD prophylaxis with CsA and sirolimus. With a median follow-up ...
< 4 5 6 7 8 9 10 11 12 13 14 >