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Results 301 - 350 of 3890
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Gensicke H - - 2012
BACKGROUND AND PURPOSE: Antecedent surgery has been described to trigger Guillain/x96Barré syndrome (GBS), but its evidence is poor and based on case reports only. METHODS: We performed a retrospective analysis of 63 patients with GBS admitted to the University Hospital Basel and University Children's Hospital Basel from January 2005 to ...
Jarvie Brooke C - - 2012
Hypothalamic proopiomelanocortin (POMC) neurons have traditionally been defined by their peptide transmitters, which are important regulators of energy balance and reward. Recent work shows that POMC neurons can also release the amino acid transmitters GABA and glutamate, although studying GABA- and glutamatergic populations of POMC neurons has been hindered by ...
Sundvik Maria - - 2012
Histamine is an essential factor in the ascending arousal system (AAS) during motivated behaviors. Histamine and hypocretin/orexin (hcrt) are proposed to be responsible for different aspects of arousal and wakefulness, histamine mainly for cognitive and motivated behaviors. We have in this study visualized the entire histaminergic neuron population in adult ...
Mamedov Tarlan - - 2012
Application of tools of molecular biology and genomics is increasingly leading towards the development of recombinant protein-based biologics. As such, it is leading to an increased diversity of targets that have important health applications and require more flexible approaches for expression because of complex post-translational modifications. For example, Plasmodium parasites ...
Pezzotta S - - 2012
Current treatment of ocular GVHD (oGVHD), represented by systemic immunosuppressive regimens and local therapies (mainly artificial tears and corticosteroids), gives unsatisfactory results. We investigated the safety and efficacy of autologous plasma rich in PDGFs to treat oGVHD unresponsive to standard medications. A total of 23 patients with refractory oGVHD (grade ...
Tamta Hemlata - - 2012
Toxicity of pyrrolizidine alkaloids (PAs) largely depends on their metabolic activation by hepatic enzymes, including cytochrome P450s, to become chemically reactive pyrrolic derivatives. These then spontaneously release the esterifying acids to generate carbonium ions that form covalent adducts with cellular nucleophiles to exhibit toxicity. In our investigation, metabolism-mediated toxicity of ...
Tarján Miklós - - 2012
Abstract Objective.The aim of the study was to refine the methodology for discriminating the ductal (DAP) and acinar adenocarcinomas (AAP) of the prostate and confirm that prostate carcinoma of ductal origin is a more aggressive subtype. Material and methods. A retrospective analysis of 110 consecutive radical prostatectomy cases operated on ...
Guo Wenxi - - 2012
We present a new approach to fabricate an integrated power pack by hybridizing an energy harvest and storage processes. This power pack incorporates dye-sensitized solar cell (DSSC) and lithium ion battery (LIB) on the same Ti foil that has double-sided TiO2 nanotube (NTs) arrays. The solar cell part is made ...
Gwathmey Kelly - - 2012
Neurologists commonly use therapeutic plasma exchange (TPE) to treat a number of conditions. This concise review examines the most common neurologic indications for TPE. It focuses on Guillain-Barre' syndrome and myasthenia gravis and also the role of TPE in chronic inflammatory demyelinating polyneuropathy, Lambert-Eaton syndrome, multiple sclerosis, neuromyelitis optica, paraproteinemic ...
Zhou Erjun - - 2012
A new alternating copolymer of fluorene and naphthalene diimide, PF-NDI, was synthesized and characterized. The highest power conversion efficiency of all-polymer solar cells based on P3HT:PF-NDI reached 1.63% with a relatively high fill factor of 0.66 by using 1,8-diiodooctane as a solvent additive to optimize the mixing morphology.
Sipponen Taina - - 2012
Abstract Objective. Data on fecal calprotectin and S100A12 in predicting wireless capsule endoscopy (WCE) findings in suspicion of Crohn's disease (CD) are scarce. Our aim was to study the role of calprotectin and S100A12 in predicting inflammatory lesions of small bowel in patients undergoing WCE. Material and methods. 84 patients ...
Chitrapriya Nataraj - - 2012
The photo-induced cleavage of pGEM-7zf-NIS super-coiled DNA by Cu(ii)-meso-tetrakis(n-N-methylpyridiniumyl)porphyrins (n = 2, 3, 4 referred to as o-, m- and p-CuTMPyP, respectively) and their binding mode were investigated in this study. m-CuTMPyP was most efficient in cleavage than o- and p-CuTMPyP isomers. Cleavage was suppressed by N(2) bubbling, suggesting that ...
Ota Y - - 2012
OTA Y., MORITO A., FUJISAWA K., NISHIDA M., HATA H., UENO T., YURIKUSA T. & MURATA T. (2012) European Journal of Cancer Care Evaluation of a moisturising micro-gel spray for prevention of cell dryness in oral mucosal cells: an in vitro study and evaluation in a clinical setting A moisturising ...
Ebrahimzadeh Samira - - 2012
Aims and objectives.  To evaluate the correlation between maternal fatigue and uterine contraction pattern at the beginning of the active phase of labour. Background.  Fatigue is one of the most common complaints in pregnant women that often continues until delivery. Maternal fatigue prolongs the labour process and increases the rate ...
Ljujic Vanja - - 2012
This study examines the relationships between nationalism and integration attitudes on one hand, and anti-Roma prejudice on the other. Using Stephan and Stephan's threat theory, the study analyzes whether and to what extent these relationships are mediated by perceived economic and symbolic threats. Data were collected among 16- and 17-year-old ...
Zhao Ming - - 2012
In recent years, cationic polymeric magnetic liposomes have shown greater stability and prolonged circulation half-life over traditional liposomes. Here, we examined the capability of cationic polymeric magnetic liposomes in delivering drugs into the brain under magnetic targeting with paclitaxel as the loaded agent. We found that the fabricated paclitaxel-loaded magnetic ...
Eicher Simone C - - 2012
The Gram-negative genus Bartonella comprises arthropod-borne pathogens that typically infect mammals in a host-specific manner. Bartonella bacilliformis and Bartonella quintana are human-specific pathogens, while several zoonotic bartonellae specific for diverse animal hosts infect humans as an incidental host. Clinical manifestations of Bartonella infections range from mild symptoms to life-threatening disease. Following ...
Pereira Arturo - - 2012
BACKGROUND: The temporal pattern of the biologic mechanism linking red blood cell (RBC) storage duration with clinical outcomes is yet unknown. This study investigates how such a temporal pattern can affect the power of randomized controlled trials (RCT) to detect a relevant clinical outcome mediated by the transfusion of stored ...
Campanella Fabio - - 2012
The existence of semantic access disorders is now well established, however the precise cognitive and anatomical underpinnings are still debated. Here we describe the case of a patient that became aphasic after the resection of a left frontal glioma. Detailed lesion reconstruction indicates that the lesion was mostly restricted to ...
Li Zhuo - - 2012
The biliopancreatic diversion surgery with duodenal switch (BPD-DS) is a surgical procedure that not only induces significant weight loss, but also promotes remission of diabetes. However, the mechanism responsible for this insulin-potentiating effect (both on sensitivity and production) is not yet clearly understood. The insulin-like growth factor (IGF) binding protein ...
Spiess Philippe E - - 2012
Study Type - Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Little is known about the prognostic impact of body mass index (BMI) and obesity on patients with locally advanced kidney cancer. Previous studies suggest that clinical/pathological stage, the proximal extent ...
Kurup Anil Nicholas - - 2012
Study Type - Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Growth of small renal masses has been shown to be variable, with mean growth rates ranging from 1 to 5 mm/year in several series. Small numbers of oncocytomas in these series ...
Josephs K A - - 2012
BACKGROUND: The progressive supranuclear palsy syndrome (PSPS) and corticobasal syndrome (CBS) are associated with relatively specific patterns of atrophy; the former predominantly involving the brainstem, the latter frontoparietal regions. However, it has become apparent that there are subjects that meet criteria for PSPS and CBS. We refer to subjects with ...
Budäus Lars - - 2012
Study Type - Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Different tools allow the individual estimation of the various endpoints in patients with prostate cancer. The Cancer of the Prostate Risk Assessment (CAPRA) score is an easy to calculate prediction ...
Eckert Kerstin - - 2012
The dynamics of A + B → C reaction fronts is studied under modulated gravitational acceleration by means of a combination of parabolic flight experiments and numerical simulations. During modulated gravity the front position undergoes periodic modulation with an accelerated front propagation under hyper-gravity together with a slowing down under ...
Sakaue Shohei - - 2012
Two terbium ions in a triple-decker complex (Pc)Tb(Pc)Tb(T(p-OMe)PP) (Pc = phthalocyaninato, T(p-OMe)PP = tetra-p-methoxyphenylporphyrinato) have shown sharply different magnetic behaviours depending on symmetry of the coordination polyhedron. The fast quantum tunnelling relaxation process in a square-prismatic site has been revealed to be hindered by magnetic-dipolar coupling between the f-electronic systems.
Fujita H - - 2012
Background: Nafamostat mesilate (NM), a protease inhibitor, is available for acute pancreatitis and disseminated intravascular coagulopathy and is used as an anticoagulant for haemodialysis in Japan. Co-infusion of red cell concentrates (RCC) and intravenous drugs is usually contraindicated. Because of limited venous access, adherence to the guidelines may be compromised ...
Liu Juan - - 2012
In this review, we summarize the major fundamental advances in immunological research reported in 2011. The highlights focus on the improved understanding of key questions in basic immunology, including the initiation and activation of innate responses as well as mechanisms for the development and function of various T-cell subsets. The ...
Myer Landon - - 2012
Abstract Initiation of antiretroviral therapy (ART) in pregnancy is an important intervention to prevent the mother-to-child transmission (MTCT) of HIV and to promote maternal health. Early initiation of ART is particularly important to achieve viral suppression rapidly before delivery. However, current approaches to start ART in pregnancy may be problematic ...
Rojas Castro D - - 2012
Abstract The publication of the "Swiss Statement" in 2008 shook the international HIV prevention and advocacy scene. HIV behavioral research has provided us with some studies focusing on the potential changes that new prevention strategies can produce, but results are not conclusive. Besides, there is a lack of data concerning ...
Yao F - - 2012
The purpose of this study is to investigate the possible underlying pathogenesis of erectile dysfunction(ED) in young men with low risk of coronary heart disease and no well-known aetiology. To conduct this study, 122 patients with ED under the age of 40 were enrolled, along with 33 age-matched normal control ...
Kim Jury - - 2012
Objective  To determine the effect of 0.5% proparacaine in tonometry by evaluating corneal touch threshold (CTT) and intraocular pressure (IOP). Animal studied  Nine rats (18 eyes, Sprague-Dawley) and 10 dogs (20 eyes, Beagle) Procedures  The IOP and CTT were measured in each eye before and after topical anesthesia with 0.5% ...
Schinkel-Ivy Alison - - 2012
The purpose of this study was to determine whether modifying an existing, highly biofidelic full body finite element model [total human model for safety (THUMS)] would produce valid amplitude and temporal shock wave characteristics as it travels proximally through the lower extremity. Modifying an existing model may be more feasible ...
Smith Lauren B - - 2012
Blood products are scarce resources requiring prudent and reasoned allocation. The utilization of red blood cells and platelets in terminally ill patients can be complicated and requires guidelines tempered by individualized considerations. Representative cases are discussed in which blood products are requested or utilized by patients at the end of ...
Yuan Huiming - - 2012
An on-line integrated platform for proteome profiling was established, with combination of protein separation by micro-reversed phase liquid chromatography (μRPLC), on-line acetonitrile (ACN) removal and pH adjustment by a hollow fiber membrane interface (HFMI), on-line digestion by an immobilized enzymatic microreactor (IMER), as well as peptide separation and proteins identification ...
Herzer Nicole - - 2012
A printable hydrogen bonded cholesteric liquid crystal (CLC) polymer film has been fabricated that after conversion to a hygroscopic polymer salt film responds to temperature and humidity by changing its reflection color. Fast responding humidity sensors have been made in which the reflection color changes between green and yellow depending ...
Hodges E - - 2012
Modern ventilators provide capnography monitoring in patients with tracheal tubes, in compliance with national and international recommendations. This technology is often not used when patients' lungs are non-invasively ventilated; however, it should be accessed immediately following tracheal intubation to confirm tube placement. This study assessed the effect of ventilation interface ...
Mori Mattia - - 2012
Dry eye syndrome (DES) or keratoconjunctivitis sicca is an eye disease caused by the chronic lack of lubrication and moisture of the eye. The pathogenesis of DES involves the over-expression and over-activity of corneal Matrix Metalloproteinase 9 (MMP-9). We propose herein a new, non-symptomatic, approach for the treatment of DES ...
Thorbergsson Palmi Thor - - 2012
Brain-machine interfaces (BMIs) may be used to investigate neural mechanisms or to treat the symptoms of neurological disease and are hence powerful tools in research and clinical practice. Wireless BMIs add flexibility to both types of applications by reducing movement restrictions and risks associated with transcutaneous leads. However, since wireless ...
Leonardi Rosalia - - 2012
Abstract Objective: To investigate condylar symmetry and condyle fossa relationships in subjects with functional posterior crossbite comparing findings before and after rapid maxillary expansion (RME) treatment through low-dose computed tomography (CT). Materials and Methods: Twenty-six patients (14 girls and 12 boys, mean age 9.6 ± 1.4 years) with functional posterior crossbite ...
Koroleva A - - 2012
In this study, we explore the production of well-defined macroscopic scaffolds with two-photon polymerization (2PP) and their use as neural tissue engineering scaffolds. We also demonstrate that these 3D scaffolds can be replicated via soft lithography, which increases production efficiency. Photopolymerizable polylactic acid (PLA) was used to produce scaffolds by ...
Wimo Anders - - 2012
Abstract Objective: To analyse the economic impact of galantamine, based on basic activities of daily living (ADL). Methods: Data were derived from Swedish patients enrolled in a 6-month placebo-controlled trial of galantamine (GAL-INT-1; n = 80), and from the Kungsholmen-Nordanstig Project, a longitudinal study of 919 elderly persons in Sweden. Basic ADL ...
Davis A M - - 2012
The ecological opportunities associated with transitions across the marine-freshwater interface are regarded as an important catalyst of diversification in a range of aquatic taxa. Here, we examined the role of these major habitat transitions and trophic diversification in a radiation of Australasian fishes using a new molecular phylogeny incorporating 37 ...
Schmal Hagen - - 2012
Background aims. Bone morphogenetic protein-2 (BMP-2) and its receptor type 1A (BMPR-1A) play significant roles in cartilage metabolism. The aim of this study was to evaluate a possible correlation between intra-articular expression of these proteins and the degree of osteoarthritis (OA) in human knees. Methods. Biopsies of synovia and debrided ...
Rojas Castro D - - 2012
Abstract Barebacking has been, since its emergence in the 1990s, a very controversial issue, and has as many definitions as authors writing about it. In France, sexual risk reduction strategies have been very contentious, and the advent of the bareback phenomenon increased this conflictual situation. This state of affairs has ...
Penmatsa Varun - - 2012
Integrating graphene onto three-dimensional (3D) microelectrodes is a plausible technique to significantly improve the sensitivity of electrochemical devices. However, the construction of graphene coated 3D microstructures has been a considerable challenge. In this paper, we present a simple methodology using electrostatic spray deposition (ESD) to conformally coat graphene onto 3D ...
Kong Feng - - 2012
Over the past decade, emotional intelligence (EI) has received much attention in the literature. Previous studies indicated that higher trait or ability EI was associated with greater mental distress. The present study focused on mediating effects of positive and negative affect on the association between trait EI and mental distress ...
Podlasz P - - 2012
Despite the known importance of galanin in the nervous system of vertebrates, the galanin gene structure, expression and consequences of galanin deficiency in developing zebrafish are unknown. We cloned the galanin gene, analyzed its expression using in situ hybridization, PCR and immunocytochemistry throughout the early development of zebrafish until the ...
Scandura Salvatore - - 2012
Abstract  Background and aim of the study: The safety of percutaneous mitral valve repair with the MitraClip system has been documented. However, few data are available on high-risk patients not amenable to surgery. The aim of this study was to evaluate the outcomes of patients with prior cardiac surgery undergoing ...
Facio Jr Fernando N - - 2012
Study Type - Aetiology (case control) Level of Evidence 3b What's known on the subject? and What does the study add? Penile rehabilitation is still controversial regarding good results. Our study shows a non-invasive treatment option to recovery after cavernous nervous damage. The assessment of changes in the intracavernous pressure and ...
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