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Turner G A - - 2012
Dandruff is characterized by a flaky, pruritic scalp and affects up to half the world's population post-puberty. The aetiology of dandruff is multifactorial, influenced by Malassezia, sebum production and individual susceptibility. The commensal yeast Malassezia is a strong contributory factor to dandruff formation, but the presence of Malassezia on healthy ...
Wang Y-S - - 2012
  To provide the observation that sodium citrate induced apoptosis in biocontrol yeast Cryptococcus laurentii.   The viability of the yeast cells was evaluated using the percentage of colony-forming units (CFU) of treated cells. The induction of cell death was dependent on the concentration of sodium citrate and exhibited typical ...
Leongamornlert D D Oncogenetics Team, The Institute of Cancer Research, Sutton SM2 5NG, - - 2012
Prostate cancer (PrCa) is one of the most common cancers affecting men but its aetiology is poorly understood. Family history of PrCa, particularly at a young age, is a strong risk factor. There have been previous reports of increased PrCa risk in male BRCA1 mutation carriers in female breast cancer ...
Dhillon Sohita - - 2012
Bevacizumab is a recombinant, humanized anti-vascular endothelial growth factor (VEGF) monoclonal antibody that neutralizes the biological activity of VEGF and inhibits tumour angiogenesis. In two pivotal, well designed, phase III, clinical trials (GOG-0218 and ICON7) in women with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer, first-line treatment with ...
Yun Byeong Hwa - - 2012
Aristolochic acids (AAs) are a structurally related family of nephrotoxic and carcinogenic nitrophenanthrene compounds found in Aristolochia herbaceous plants, many of which have been used worldwide for medicinal purposes. AAs have been implicated in the etiology of so-called Chinese herbs nephropathy and of Balkan endemic nephropathy. Both of these disease ...
Lazar-Antman Meredith A - - 2012
Obese children have a theoretically increased risk of sustaining an extremity fracture because of potential variations in their bone mineral density, serum leptin levels, and altered balance and gait.Trauma databases suggest an increased rate of extremity fractures in obese children and adolescents involved in polytrauma compared with nonobese children and ...
Miyanji Firoz - - 2012
The treatment of patients with large adolescent idiopathic scoliosis curves has been associated with increased surgical complexity. The purpose of this study was to determine whether surgical correction of larger adolescent idiopathic scoliosis curves increased the utilization of health-care resources and to identify potential predictors associated with increased perioperative health-care ...
Penner Murray John - - 2012
End-stage arthritis may be associated with increased body mass index (BMI). Overweight patients with ankle arthritis often request surgery in the hope that this will allow them to initiate a weight loss program. One hundred and forty-five overweight (BMI = 25.1 to 29.9 kg/m2) or obese (BMI > 30 kg/m2) ...
Harris N Lindsay - - 2012
Platelet-rich plasma is reported to contain multiple growth factors, and has been utilized in orthopaedic surgery to aid healing in multiple tissues. To date, the use of autologous platelet-rich plasma has not been studied for its effects on normal soft tissue. Eighteen adult New Zealand White rabbits were injected with ...
Radcliff Tiffany A - - 2012
Intramedullary nails for stabilizing intertrochanteric proximal femoral fractures have been available since the early 1990s. The nails are inserted percutaneously and have theoretical mechanical advantages over plates and screws, but they have not been demonstrated to improve patient outcomes. Still, use of intramedullary nails is becoming more common. The goal ...
de Putter C E - - 2012
Injuries to the hand and wrist account for approximately 20% of patient visits to emergency departments and may impose a large economic burden. The purpose of this study was to estimate the total health-care costs and productivity costs of injuries to the hand and wrist and to compare them with ...
Gray Chancellor F - - 2012
Dissociation of the polyethylene liner from the acetabular shell is an uncommon event. Offset, face-changing polyethylene liners theoretically increase femoral head coverage, allow for larger heads with smaller cup diameters, and offer improved stability without risk of impingement. However, we present four cases of liner dissociations from the acetabular shell ...
Segal Ava D - - 2012
Ankle arthritis, like hip and knee arthritis, has a substantial impact on patient function. Understanding the functional limitations of ankle arthritis may help to stratify treatment strategies. We measured the preoperative demographic characteristics, physical function, and self-assessed function of patients with end-stage ankle arthritis and identified correlations among these metrics. ...
Bozic Kevin J - - 2012
The patient-related risk factors for periprosthetic joint infection and postoperative mortality in elderly patients undergoing total hip arthroplasty are poorly understood. The purpose of this study was to identify the specific patient comorbidities that are associated with an increased risk of periprosthetic joint infection and of ninety-day postoperative mortality in ...
Dominguez-Medina Sergio - - 2012
We present in situ observations of adsorption of bovine serum albumin (BSA) on citrate-stabilized gold nanospheres. We implemented scattering correlation spectroscopy as a tool to quantify changes in the nanoparticle brownian motion resulting from BSA adsorption onto the nanoparticle surface. Protein binding was observed as an increase in the nanoparticle ...
Kurmis Andrew P - - 2012
The analgesic efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) is well established, and these agents often form an integral part of posttraumatic pain management. However, potentially deleterious effects of resulting prostaglandin suppression on fracture-healing have been suggested. A systematic literature review involving searches of electronic databases and online sources was performed ...
Patwardhan Avinash G - - 2012
The biconvex mobile core of the CHARITÉ lumbar disc prosthesis forms two joints (spherical bearings) with the metal end plates. We quantified the intra-prosthesis motion to test the hypothesis that the total prosthesis motion would not be equally distributed between the two bearings of implanted CHARITÉ discs, which might explain ...
Fucentese Sandro F - - 2012
The natural history of small, symptomatic rotator cuff tears is currently unclear. The purpose of the present study was to assess the clinical and structural outcomes for a consecutive series of patients with symptomatic, isolated full-thickness supraspinatus tears who had been offered rotator cuff repair but declined operative treatment. In ...
Smith Toby O - - 2012
Triangular fibrocartilaginous complex (TFCC) tears are common sources of ulnar-sided wrist pain and resultant functional disability. Diagnosis is based on the history and clinical examination as well as radiographic evidence of a TFCC central perforation or a radial/ulnar tear. The purpose of this study was therefore to evaluate the diagnostic ...
De La Rocha Adriana - - 2012
Larsen syndrome is associated with multiple complications, including spinal deformities and recalcitrant joint dislocations. We noted capital femoral ossific nuclei on ultrasonographic images that were made for two infants with Larsen syndrome who were less than two weeks of age. We sought to confirm that this finding is common in ...
Thota Anilkrishna B - - 2012
To improve the quality of depression management, collaborative care models have been developed from the Chronic Care Model over the past 20 years. Collaborative care is a multicomponent, healthcare system-level intervention that uses case managers to link primary care providers, patients, and mental health specialists. In addition to case management ...
Lee Lore E - - 2012
We tested fecal samples from 93 norovirus-negative gastroenteritis outbreaks; 21 outbreaks were caused by sapovirus. Of these, 71% were caused by sapovirus genogroup IV and 66% occurred in long-term care facilities. Future investigation of gastroenteritis outbreaks should include multi-organism testing.
O'Byrne P M - - 2012
Patients with severe refractory asthma have not achieved asthma control, even with high doses of ICS, usually in combination with LABAs and other maintenance treatments. The most promising approaches currently under investigation are those which reduce airway eosinophils in patients with severe refractory asthma and a persisting airway eosinophilia. Monoclonal ...
Hemmige Vagish - - 2012
Chagas disease, an infection caused by the protozoan Trypanosoma cruzi and transmitted by the Reduuvid insect vector, remains a major cause of morbidity in Central and South America over a century after its discovery in 1909. Though major advances in preventing the spread of this disease have been made in ...
Möller M - - 2012
Möller M., Schaupp E., Massumi-Möller N., Zeyher C., Godt A., Berneburg M. Reference values for three-dimensional surface cephalometry in children aged 3-6 years Orthod Craniofac Res 2012; 15: 103-116. © 2012 John Wiley & Sons A/S STRUCTURED ABSTRACT: Objective -  This prospective cross-sectional study design was performed to define reference values for ...
Bennetzen Martin V - - 2012
Macroautophagy is a self-cannibalistic process that enables cells to adapt to various stresses and maintain energy homeostasis. Additionally, autophagy is an important route for turnover of misfolded proteins and damaged organelles, with important implications in cancer, neurodegenerative diseases and aging. Resveratrol and spermidine are able to induce autophagy by affecting ...
Pucket Jonathan D - - 2012
Case Description-A 9-year-old castrated male Bichon Frise was evaluated because of a 3-week history of a nonhealing corneal ulcer and corneal pigmentation of the left eye. Clinical Findings-Ophthalmic examination of the left eye revealed conjunctival hyperemia, corneal neovascularization, corneal edema, corneal ulceration, and central corneal pigmentation. Intraocular structures of the ...
Hussain Tarique - - 2012
Purpose: To identify which rest phase (systolic or diastolic) is optimum for assessing or measuring cardiac structures in the setting of three-dimensional (3D) whole-heart imaging in congenital heart disease (CHD). Materials and Methods: The study was approved by the institutional review board; informed consent was obtained. Fifty children (26 male ...
van Leeuwen Ingeborg M M - - 2012
Pharmacological activation of wild-type p53 has been found to protect normal cells in culture from cytotoxicity and nuclear aberrations caused by conventional cancer therapeutics. Hence, small-molecule p53 activators could have clinical benefits as chemoprotectants for cancer patients bearing p53-mutant tumors. We have evaluated 16 p53-based cyclotherapy regimes combining p53 activators ...
Lehavot Keren - - 2012
Women who have served in the military are a rapidly growing population. No previous studies have compared directly their health status to that of civilians. To provide estimates of several leading U.S. health indicators by military service status among women. Data were obtained from the 2010 Behavioral Risk Factor Surveillance ...
Frank Lawrence D - - 2012
GIS-based walkability measures designed to explain active travel fail to capture "playability" and proximity to healthy food. These constructs should be considered when measuring potential child obesogenic environments. The aim of this study was to describe the development of GIS-based multicomponent physical activity and nutrition environment indicators of child obesogenic ...
Petersen Randi Føns - - 2012
We used multilocus variable-number tandem repeat analysis and multiple antigen sequence typing to characterize isolates of Bordetella pertussis strains circulating in Denmark during periods with and without pertussis vaccination coverage. Our results show substantial shifts in the B. pertussis population over time and a reduction in genetic diversity. These changes ...
McLellan Christopher P - - 2012
ABSTRACT: McLellan, CP and Lovell, DI. Neuromuscular responses to impact and collision during elite rugby league match play. J Strength Cond Res 26(5): 1431-1440, 2012-The purpose of this study was to investigate the relationship between the prematch and short-term postmatch neuromuscular responses to the intensity, number, and distribution of impacts ...
Lee Bae-Young - - 2012
Purpose: To evaluate the evidence on the value of preparative fluid fasting for patients undergoing elective computed tomography (CT) with intravenous administration of contrast material and to survey leading institutions in a number of countries on their current policies in this regard. Materials and Methods: This study qualified for exempt ...
Wanner Miriam - - 2012
Physical activity has various health benefits. Active transport can contribute to total physical activity and thus affect body weight because of increased energy expenditure. This review summarizes published evidence on associations of active transport, general physical activity, and body weight in adults. A systematic review of the literature was conducted ...
Fraser Lorna K LK School of Geography, University of Leeds, United Kingdom. - - 2012
The childhood obesity epidemic is a current public health priority in many countries, and the consumption of fast food has been associated with obesity. This study aims to assess the relationship between fast-food consumption and obesity as well as the relationship between fast-food outlet access and consumption in a cohort ...
Blakey J D - - 2012
Asthma is common, and some individuals are severely affected by it. Learned institutions have sought to provide a definition of 'severe asthma' to facilitate research and clinical care. This is a challenging undertaking given the difficulty in defining asthma and the lack of supportive evidence for a distinct severe asthma ...
Ahn Ji Young - - 2012
Hyaluronic acid (HA) dermal fillers are widely used to reduce the appearance of aging. However, comparative research on the efficacy and safety of products of similar composition is limited. We compared outcomes achieved with two non-cross-linked HA fillers of almost identical composition, Mesoglow(®) and IAL System(®) . Forty subjects with ...
Kute Vivek B - - 2012
Plasmodium vivax is causing increasingly more cases of severe malaria worldwide. Among 25 cases in India during 2010-2011, associated conditions were renal failure, thrombocytopenia, jaundice, severe anemia, acute respiratory distress syndrome, shock, cerebral malaria, hypoglycemia, and death. Further studies are needed to determine why P. vivax malaria is becoming more ...
McDonald V M - - 2012
Exacerbations occur frequently in severe asthma. They result in significant morbidity and can lead to hospitalization and death. Severe exacerbations can also lead to an accelerated decline in lung function. Phenotyping severe asthma can aid with both prognostication of exacerbation risk and maintenance treatment selection to minimize future risks of ...
Hawryluk Elena B - - 2012
Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of ...
Cacciò Simone M - - 2012
Dientamoeba fragilis is a common intestinal parasite in humans. Transmission routes and natural host range are unknown. To determine whether pigs are hosts, we analyzed 152 fecal samples by microscopy and molecular methods. We confirmed that pigs are a natural host and harbor genotypes found in humans, suggesting zoonotic potential.
Guadagnoli Mark - - 2012
The current paper describes a model of learning that has been used to produce efficient learning, thus yielding greater retention of information and superior performance under stress. In this paper, the model is applied to the learning of technical skills. After a brief review of the learning-performance paradox and other ...
Sanchez-Vaznaugh Emma V - - 2012
Physical education policies have received increased attention as a means for improving physical activity levels, enhancing physical fitness, and contributing to childhood obesity prevention. Although compliance at the school and district levels is likely to be critical for the success of physical education policies, few published studies have focused on ...
Greene Carol - - 2012
Multiple stressors are affecting the mental and physical health of entire populations. In this pilot study, the experience of a guided imagery presentation through the Internet reduced stress in a convenience sample of 29 adult participants as evidenced by a self-reported single-item rating scale question administered pre- and postintervention. Demographics ...
Richardson Kristy L - - 2012
ABSTRACT: Richardson, KL, Coburn, JW, Beam, WC, and Brown, LE. Effects of isocaloric carbohydrate vs. carbohydrate-protein supplements on cycling time to exhaustion. J Strength Cond Res 26(5): 1361-1365, 2012-The purpose of this study was to investigate the effects of isocaloric carbohydrate (CHO) and carbohydrate-protein (CHO-Pro) supplements on time to exhaustion. ...
Go Pauline H - - 2012
Medical Education 2012: 46: 491-500 Objectives  This study sought to evaluate the practices and perceptions of US residency programme directors (PDs) and residency applicants with reference to the use of social media and Internet resources in the resident doctor selection process. Methods  A survey was distributed via e-mail (SurveyMonkey(®) ) ...
Thoeny Harriet C - - 2012
Diffusion-weighted (DW) magnetic resonance (MR) imaging has a large number of potential clinical applications in the female and male pelvis and can easily be added to any routine MR protocol. In the female pelvis, DW imaging allows improvement of staging in endometrial and cervical cancer, especially in locally advanced disease ...
Cohen Jeffrey A JA Mellen Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA. - - 2012
Many of the available disability outcome measures used in clinical trials of multiple sclerosis are insensitive to change over time, inadequately validated, or insensitive to patient-perceived health status or quality of life. Increasing focus on therapies that slow or reverse disability progression makes it essential to refine existing measures or ...
Kennedy J L JL University of Virginia Asthma and Allergic Diseases Center, Charlottesville, VA, - - 2012
The classification of asthma to identify forms which have different contributing causes is useful for all cases in which the disease requires regular treatment, but it is essential for the management of severe asthma. Many forms of the disease can occur, and complex mixtures are not uncommon; here we artificially ...
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