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Wang Y-S - - 2012
  To provide the observation that sodium citrate induced apoptosis in biocontrol yeast Cryptococcus laurentii.   The viability of the yeast cells was evaluated using the percentage of colony-forming units (CFU) of treated cells. The induction of cell death was dependent on the concentration of sodium citrate and exhibited typical ...
Leongamornlert D - - 2012
Prostate cancer (PrCa) is one of the most common cancers affecting men but its aetiology is poorly understood. Family history of PrCa, particularly at a young age, is a strong risk factor. There have been previous reports of increased PrCa risk in male BRCA1 mutation carriers in female breast cancer ...
Dhillon Sohita - - 2012
Bevacizumab is a recombinant, humanized anti-vascular endothelial growth factor (VEGF) monoclonal antibody that neutralizes the biological activity of VEGF and inhibits tumour angiogenesis. In two pivotal, well designed, phase III, clinical trials (GOG-0218 and ICON7) in women with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer, first-line treatment with ...
Yun Byeong Hwa - - 2012
Aristolochic acids (AAs) are a structurally related family of nephrotoxic and carcinogenic nitrophenanthrene compounds found in Aristolochia herbaceous plants, many of which have been used worldwide for medicinal purposes. AAs have been implicated in the etiology of so-called Chinese herbs nephropathy and of Balkan endemic nephropathy. Both of these disease ...
Gray Chancellor F - - 2012
Dissociation of the polyethylene liner from the acetabular shell is an uncommon event. Offset, face-changing polyethylene liners theoretically increase femoral head coverage, allow for larger heads with smaller cup diameters, and offer improved stability without risk of impingement. However, we present four cases of liner dissociations from the acetabular shell ...
Smith Toby O - - 2012
Triangular fibrocartilaginous complex (TFCC) tears are common sources of ulnar-sided wrist pain and resultant functional disability. Diagnosis is based on the history and clinical examination as well as radiographic evidence of a TFCC central perforation or a radial/ulnar tear. The purpose of this study was therefore to evaluate the diagnostic ...
Bozic Kevin J - - 2012
The patient-related risk factors for periprosthetic joint infection and postoperative mortality in elderly patients undergoing total hip arthroplasty are poorly understood. The purpose of this study was to identify the specific patient comorbidities that are associated with an increased risk of periprosthetic joint infection and of ninety-day postoperative mortality in ...
De La Rocha Adriana - - 2012
Larsen syndrome is associated with multiple complications, including spinal deformities and recalcitrant joint dislocations. We noted capital femoral ossific nuclei on ultrasonographic images that were made for two infants with Larsen syndrome who were less than two weeks of age. We sought to confirm that this finding is common in ...
Radcliff Tiffany A - - 2012
Intramedullary nails for stabilizing intertrochanteric proximal femoral fractures have been available since the early 1990s. The nails are inserted percutaneously and have theoretical mechanical advantages over plates and screws, but they have not been demonstrated to improve patient outcomes. Still, use of intramedullary nails is becoming more common. The goal ...
Segal Ava D - - 2012
Ankle arthritis, like hip and knee arthritis, has a substantial impact on patient function. Understanding the functional limitations of ankle arthritis may help to stratify treatment strategies. We measured the preoperative demographic characteristics, physical function, and self-assessed function of patients with end-stage ankle arthritis and identified correlations among these metrics. ...
Kurmis Andrew P - - 2012
The analgesic efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) is well established, and these agents often form an integral part of posttraumatic pain management. However, potentially deleterious effects of resulting prostaglandin suppression on fracture-healing have been suggested. A systematic literature review involving searches of electronic databases and online sources was performed ...
Fucentese Sandro F - - 2012
The natural history of small, symptomatic rotator cuff tears is currently unclear. The purpose of the present study was to assess the clinical and structural outcomes for a consecutive series of patients with symptomatic, isolated full-thickness supraspinatus tears who had been offered rotator cuff repair but declined operative treatment. In ...
Penner Murray John - - 2012
End-stage arthritis may be associated with increased body mass index (BMI). Overweight patients with ankle arthritis often request surgery in the hope that this will allow them to initiate a weight loss program. One hundred and forty-five overweight (BMI = 25.1 to 29.9 kg/m2) or obese (BMI > 30 kg/m2) ...
Lazar-Antman Meredith A - - 2012
Obese children have a theoretically increased risk of sustaining an extremity fracture because of potential variations in their bone mineral density, serum leptin levels, and altered balance and gait.Trauma databases suggest an increased rate of extremity fractures in obese children and adolescents involved in polytrauma compared with nonobese children and ...
Patwardhan Avinash G - - 2012
The biconvex mobile core of the CHARITÉ lumbar disc prosthesis forms two joints (spherical bearings) with the metal end plates. We quantified the intra-prosthesis motion to test the hypothesis that the total prosthesis motion would not be equally distributed between the two bearings of implanted CHARITÉ discs, which might explain ...
de Putter C E - - 2012
Injuries to the hand and wrist account for approximately 20% of patient visits to emergency departments and may impose a large economic burden. The purpose of this study was to estimate the total health-care costs and productivity costs of injuries to the hand and wrist and to compare them with ...
Miyanji Firoz - - 2012
The treatment of patients with large adolescent idiopathic scoliosis curves has been associated with increased surgical complexity. The purpose of this study was to determine whether surgical correction of larger adolescent idiopathic scoliosis curves increased the utilization of health-care resources and to identify potential predictors associated with increased perioperative health-care ...
Harris N Lindsay - - 2012
Platelet-rich plasma is reported to contain multiple growth factors, and has been utilized in orthopaedic surgery to aid healing in multiple tissues. To date, the use of autologous platelet-rich plasma has not been studied for its effects on normal soft tissue. Eighteen adult New Zealand White rabbits were injected with ...
Dominguez-Medina Sergio - - 2012
We present in situ observations of adsorption of bovine serum albumin (BSA) on citrate-stabilized gold nanospheres. We implemented scattering correlation spectroscopy as a tool to quantify changes in the nanoparticle brownian motion resulting from BSA adsorption onto the nanoparticle surface. Protein binding was observed as an increase in the nanoparticle ...
Shuval Kerem - - 2012
Studies have found that higher levels of cardiorespiratory fitness and light to moderate alcohol intake reduce the risk for premature death. Scant evidence, however, exists assessing the joint effects of both measures on all-cause and cardiovascular disease (CVD) mortality. This study aims to examine the independent and joint effects of ...
Schöttner Konrad - - 2012
In Djungarian hamsters (Phodopus sungorus) bred at the authors' institute, a certain number of animals show activity patterns incompatible with proper entrainment of their endogenous circadian pacemaker to the environmental light-dark (LD) cycle. Even though the activity-offset in these animals is stably coupled to "light-on," activity-onset is increasingly delayed, leading ...
Cristina Cantú-Salinas - - 2012
Background  Alopecia areata (AA) is a chronic inflammatory condition characterized by hair loss, most frequently from the scalp. Its etiopathogenesis is currently unknown, but inflammatory traits and associations with autoimmune diseases suggest that AA shares a similar origin. The tumor necrosis factor alpha (TNFα) gene, located on chromosome 6 within ...
Xu Li - - 2012
Lipid homeostasis is maintained through the coordination of lipid metabolism in various tissues, including adipose tissue and the liver. The disruption of lipid homeostasis often results in the development of metabolic disorders such as obesity, diabetes mellitus, liver steatosis, and cardiovascular diseases. Cell death-inducing DNA fragmentation factor 45-like effector family ...
Salfi Salvatore F - - 2012
Current evidence demonstrates that probiotics reduce diarrheal duration from a number of etiologies. Professional nursing practice based on evidence and clinical expertise supports a diet-containing probiotics to manage acute diarrhea. Dietary limitations included in the BRAT (bananas, rice, applesauce, and toast) diet recommended by many nurses need to be reexamined ...
Halıgür Beyzan Durul - - 2012
Background  Psoriasis is a common Th1-mediated skin disease whose etiology remains obscure. Loss of sweating caused by retention hyperkeratosis is seen in psoriasis plaques, which is likely to have resulted from autonomic dysfunction. Objective  In the present study, we aimed to evaluate autonomic nervous system (ANS) functions with regard to ...
Griffin Barbara - - 2012
Medical Education 2012: 46: 485-490 Objectives  The problem of dissimulation by applicants when self-report tests of personality are used for job selection has received considerable attention in non-medical contexts. Personality testing is not yet widely used in medical student selection, but this may change in the light of recent research ...
Bacon Nicholas T - - 2012
ABSTRACT: Bacon, NT, Wingo, JE, Richardson, MT, Ryan, GA, Pangallo, TC, and Bishop, PA. Effect of two recovery methods on repeated closed-handed and open-handed weight-assisted pull-ups J Strength Cond Res 26(5): 1348-1352, 2012-The purpose of this study was to examine 2 recovery modalities (with and without an ice bag treatment) ...
Gropper Adrienne B - - 2012
Although primary basal cell carcinoma (BCC) represents an extremely common malignancy, metastases derived from BCC are exceedingly rare. The prognosis for metastatic BCC is poor, and little consensus exists regarding predictive factors or optimal treatment strategies. Here, we present the case of a 63-year-old man with BCC of the neck ...
Sundaram Meenakshi - - 2012
Exchangeable apolipoproteins, composed mainly of amphipathic α-helices, are associated with various plasma lipoproteins and play an important role in the metabolism of those lipoproteins to which they bind. Accumulating experimental evidence suggests that exchangeable apolipoproteins, such as apoE, apoA-IV, and apoC-III, also play a role intracellularly in facilitating lipid recruitment ...
Mortatti Arnaldo L - - 2012
ABSTRACT: Mortatti, AL, Moreira, A, Aoki, MS, Crewther, BT, Castagna, C, de Arruda, AFS, and Filho, JM. Effect of competition on salivary cortisol, immunoglobulin A, and upper respiratory tract infections in elite young soccer players. J Strength Cond Res 26(5): 1396-1401, 2012-The present study examined the effect of a 20-day ...
Lake Jason P - - 2012
ABSTRACT: Lake, JP, Lauder, MA, and Smith, NA. Barbell kinematics should not be used to estimate power output applied to the barbell-and-body system center of mass during lower-body resistance exercise. J Strength Cond Res 26(5): 1302-1307, 2012-The aim of this study was to compare measures of power output applied to ...
Hisamatsu Tadakazu - - 2012
See article in J. Gastroenterol. Hepatol. 2012; 27: 935-944.
O'Neill Daniel K - - 2012
ABSTRACT: Heel ulcers are clinically challenging. Limited subcutaneous tissue covering the calcaneus bone makes the heel vulnerable to pressure injury. Adequate debridement of fibrotic, infected, and necrotic tissue is essential for healing. The authors report a standardized anesthesia protocol using regional anesthesia with sedation rather than general anesthesia for heel ...
Glanz Karen - - 2012
In-store food marketing can influence food-purchasing behaviors and warrants increased attention given the dramatic rise in obesity. Descriptive and experimental studies of key marketing components have been conducted by consumer scientists, marketing researchers, and public health experts. This review synthesizes research and publications from industry and academic sources and provides ...
Rainham Daniel G - - 2012
Physical activity is an essential element in reducing the prevalence of obesity, but much is unknown about the intensity and location of physical activity among youth-this is important because adolescent health behaviors are predictive of behaviors in adults. This study aims to identify the locations where youth moderate-to-vigorous physical activity ...
Poon A H - - 2012
SUMMARY: Patients with severe asthma have asthma symptoms which are difficult to control, require high dosages of medication, and continue to experience persistent symptoms, asthma exacerbations or airflow obstruction. Epidemiological and clinical evidences point to the fact that severe asthma is not a single phenotype. Cluster analyses have identified subclasses ...
Ozkan Ilker - - 2012
Background  Topical drugs enhance the therapeutic effects of ultraviolet (UV)-based therapy for psoriasis. However, their efficacy has yet to be established in a clinical trial. Objectives  This study aimed to compare the efficacy of targeted microphototherapy alone and in combination with psoralen or calcipotriol in the treatment of plaque-type psoriasis. ...
Herzog Eva - - 2012
Purpose: To investigate whether multispectral optoacoustic tomography (MSOT) can reveal the heterogeneous distributions of exogenous agents of interest and vascular characteristics through tumors of several millimeters in diameter in vivo. Materials and Methods: Procedures involving animals were approved by the government of Upper Bavaria. Imaging of subcutaneous tumors in mice ...
Lehner Richard - - 2012
Overproduction of apolipoprotein B (apoB)-containing lipoproteins by the liver and the intestine is 1 of the hallmarks of insulin resistance and type 2 diabetes and a well-established risk factor of cardiovascular disease. The assembly of apoB lipoproteins is regulated by the availability of lipids that form the neutral lipid core ...
Lux Cassie N - - 2012
Case Description-A 7-year-old neutered male Saint Bernard was evaluated because of a 6-month history of coughing, gagging, change in phonation, excessive panting, and chronic intermittent vomiting and diarrhea. Clinical Findings-Physical examination revealed no remarkable findings other than panting. Total thyroxine concentration and results of a CBC, serum biochemistry analysis, urinalysis, ...
McBride Ali - - 2012
Purpose The pharmacology, pharmacokinetics, clinical efficacy, safety, and administration of eribulin in patients with metastatic breast cancer are reviewed. Summary Classical chemotherapeutic agents for breast cancer have dominated treatment regimens even in the era of targeted therapy. Disease progression through these agents is often due to the development of resistance ...
Okonta Nkechi Rose - - 2012
The aim of this article was to present a evidence-based integrative research review that validates yoga therapy as an effective complementary treatment in the management of high blood pressure (BP). The article also uses the theoretical framework of Dr Hans Selye's general adaptation syndrome. Yoga researchers demonstrate that yoga works ...
Losnegard Thomas - - 2012
ABSTRACT: Losnegard, T, Myklebust, H, and Hallén, J. No differences in O2-cost between V1 and V2 skating techniques during treadmill roller skiing at moderate to steep inclines. J Strength Cond Res 26(5): 1340-1347, 2012-Elite crosscountry skiers use both the V1 and V2 techniques on moderate and steep inclines despite previous ...
Thota Anilkrishna B - - 2012
To improve the quality of depression management, collaborative care models have been developed from the Chronic Care Model over the past 20 years. Collaborative care is a multicomponent, healthcare system-level intervention that uses case managers to link primary care providers, patients, and mental health specialists. In addition to case management ...
O'Byrne P M - - 2012
Patients with severe refractory asthma have not achieved asthma control, even with high doses of ICS, usually in combination with LABAs and other maintenance treatments. The most promising approaches currently under investigation are those which reduce airway eosinophils in patients with severe refractory asthma and a persisting airway eosinophilia. Monoclonal ...
Möller M - - 2012
Möller M., Schaupp E., Massumi-Möller N., Zeyher C., Godt A., Berneburg M. Reference values for three-dimensional surface cephalometry in children aged 3-6 years Orthod Craniofac Res 2012; 15: 103-116. © 2012 John Wiley & Sons A/S STRUCTURED ABSTRACT: Objective -  This prospective cross-sectional study design was performed to define reference values for ...
Zulkowski Karen - - 2012
PURPOSE:: To enhance the learner's competence in identifying and treating moisture-associated skin damage. TARGET AUDIENCE:: This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. OBJECTIVES:: After participating in this educational activity, the participant should be better able to:1. Differentiate moisture-associated skin ...
- - 2012
On the cover: A contextual array of false-colored ID maps are the focus of the cover, generated from segmentation and cell tracking of a cluster of amnioserosa cells. Three different ID maps are used that represent differences in time and cell movement, which in this issue, Mashburn and coworkers describe ...
Le Boedec Kevin - - 2012
Objective-To determine the strength of the relationship between paradoxical breathing (PB) and spontaneous pleural diseases in dyspneic dogs and cats. Design-Cross-sectional study. Animals-Dogs (n = 195) and cats (194) with a recorded diagnosis of dyspnea examined at the National Veterinary Schools of Alfort and Toulouse (France) between January 2001 and ...
Kinner Sonja - - 2012
To evaluate the diagnostic performance of T2-weighted magnetic resonance (MR) cholangiopancreatography pulse sequences in comparison with MR cholangiopancreatography sequences combined with nonenhanced T1-weighted images in the detection of biliary cast syndrome in liver transplant recipients. This retrospective study was conducted in accordance with the declaration of Helsinki. Institutional review board ...
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