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Chow Cheryl-Emiliane T - - 2012
Marine myoviruses (i.e. bacteriophages with a contractile tail sheath) are numerically abundant and genetically diverse. We developed a terminal restriction fragment length polymorphism assay (TRFLP) for g23, the conserved gene encoding the major capsid protein, to investigate T4-like myovirus communities at USC's Microbial Observatory at the San Pedro Ocean Time-series ...
Mohaupt Jennifer - - 2012
The importance and necessity of interprofessional collaboration (IPC) present challenges for educators as they determine how best to achieve IPC through interprofessional education (IPE). Simulation-based teaching has been shown to enhance students' understanding of professional roles and promote positive attitudes toward team members; yet, empirical evidence providing direction on the ...
Liu J Y - - 2012
This study was to validate a mandarin Chinese version of Oral Health Impact Profile (OHIP-49) in China and to develop a shortened version of OHIP appropriate for use in partially dentate patients with implant-supported prostheses. The original 49 items of OHIP were translated into mandarin Chinese using a forward-backward method ...
Venugopal C - - 2012
Reasons for performing study: To determine and compare the reactive oxygen and nitrogen species (ROS and RNS) in pulmonary tissues of horses affected with recurrent airway obstruction (RAO) and clinically healthy horses, and to evaluate the effectiveness of potential therapeutic agents in reducing ROS and RNS in the tissues of ...
Gziri Mina Mhallem - - 2012
The co-occurrence of cancer and pregnancy is more frequently diagnosed. The effects of cancer treatment on maternal and fetal outcomes are less well known. The cardiotoxic effects of chemotherapy are a specific concern for the mother and fetus. We wanted to review the existing literature, mainly consisting of case reports, ...
Yarema Maksym - - 2012
Indium tin oxide (ITO) nano-patterned electrodes are prepared from colloidal solutions as material saving alternative to the industrial vapor phase deposition and top down processing. For that purpose highly monodisperse In1-xSnx (x < 0.1) colloidal nanocrystals (NCs) are synthesized with accurate size and composition control. The outstanding monodispersity of the ...
Shafran Yuri - - 2012
Novel self-condensation of 3-(azol-5-yl)-1,1-dimethylenamines has been found to form new C-C bonds leading to 2,4-(1,2,3-triazole-1,2,3-thiadiazole-3-phenylisothiazole)-(1E,3Z)-5-yl-butadiene-1-amines. The discovered reaction represents a new example of C-H functionalization in unsaturated systems and can serve an efficient synthetic approach to rational design of new 2,4-(diazole-5-yl)-dieneamines.
Zhao Shuzhi - - 2012
ABSTRACT Aims: To assess the association between the NOS3 4b/a, T-786C and G894T polymorphisms and diabetic retinopathy (DR) susceptibility. Materials and Methods: Twenty-one studies covering 8,111 subjects were included. The fixed or random effect model used was based on heterogeneity. Results: A significant association of the intron 4a allele in ...
Bobek Vladimir - - 2012
Circulating tumor cells (CTC) may reach multiple organ sites. However, CTC seeding and growth in distant organs is not random. Each metastatic site may contain a specific subpopulation of the original metastatic tumor capable of growing at that site. The fluorescent orthotopic prostate cancer model (PC-3-GFP) model was used for ...
Jia Zhiwei - - 2012
Multipurpose active capsule endoscopes (ACE) have drawn considerable attention in recent years, but these devices continue to suffer from energy limitations. In order to deliver stable and sufficient energy safely, a wireless power transmission system based on inductive coupling is presented. The system consists of a double-layer solenoid pair primary ...
Liu Shengyan - - 2012
Efficient drug delivery to the eye remains a challenging task for pharmaceutical scientists. Due to the various anatomical barriers and the clearance mechanisms prevailing in the eye, conventional drug delivery systems, such as eye drop solutions, suffer from low bioavailability. More invasive methods, such as intravitreal injections and implants, cause ...
Nigro Giovanni - - 2012
Abstract Objective: To determine if fetal hyperechogenic bowel is associated with a poor outcome with or without immunoglobulin therapy. Methods: Sixteen pregnant women whose 17 fetuses had hyperechogenic bowel were followed by a protocol of offering additional serologic testing, amniocentesis, immunoglobulins, serial ultrasounds, and evaluation of their children. Results: Of ...
Colli L - - 2012
Since its domestication, about 5000 years ago, the donkey (Equus asinus) has been extensively used as a work or draft animal in agricultural activities and for the transportation of people and goods. In the last century, technology improvement and growing mechanization strongly affected agriculture and the management and use of this ...
Herschtal A - - 2012
Early approaches to characterizing errors in target displacement during a fractionated course of radiotherapy assumed that the underlying fraction-to-fraction variability in target displacement, known as the 'treatment error' or 'random error', could be regarded as constant across patients. More recent approaches have modelled target displacement allowing for differences in random ...
Shen Bo - - 2012
Restorative proctocolectomy with ileal pouch-anal anastomosis has become the procedure of choice for the majority of patients with ulcerative colitis who require surgical treatment. Pouchitis, the most common long-term complication of the procedure, involves a spectrum of disease processes with heterogeneous risk factors, clinical features, disease courses and prognoses. In ...
Quinet Muriel - - 2012
Ferrous iron toxicity is a mineral disorder frequently occurring under waterlogged soils where rice is cultivated. To decipher the main metabolic pathways involved in rice response to iron excess, seedlings have been exposed to 125 mg L(-1) FeSO(4) for 3 weeks. A combined transcriptomic, biochemical and physiological study has been ...
Pereira do Amaral Fabiano - - 2012
The methanol extract of the flowers of Paepalanthus geniculatus Kunth. showed radical-scavenging activity in the TEAC assay. An analytical approach based on HPLC-ESIMS(n) was applied to obtain the metabolite profile of this extract and led to the rapid identification of 19 polyphenolic compounds comprising flavonoids and naphthopyranones. The new naphthopyranone ...
Wang Chun - - 2012
The item response times (RTs) collected from computerized testing represent an underutilized source of information about items and examinees. In addition to knowing the examinees' responses to each item, we can investigate the amount of time examinees spend on each item. In this paper, we propose a semi-parametric model for ...
Rideout Todd C - - 2012
Reducing intestinal cholesterol absorption with plant sterol consumption is a well-characterized strategy to lower LDL-C and potentially reduce cardiovascular disease risk. However, over 50 years of clinical research demonstrate that there is significant heterogeneity in the individual LDL-C lowering response to plant sterol therapy. A clear understanding of why plant sterols ...
Hockenhull J - - 2012
Reasons for performing study: UK leisure horses are owned primarily for riding. Ridden behaviour problems may compromise the use of the horse in this role and lead to harsh redress or relinquishment of the horse. Despite the consequences of these problems little is known about their prevalence or the working ...
Zhang Yicheng - - 2012
A novel iron-promoted tandem reaction of anilines with styrene oxides via C-C cleavage and C-H activation has been developed. The reaction utilizes an inexpensive FeCl(3) as promoter and is suitable for forming a variety of 3-arylquinolines from the simple and readily available starting materials.
Nelson-Filho Paulo - - 2012
This study evaluated the effect of the systemic use of sodium alendronate in rats in vivo. Forty-five Wistar rats aged 36 to 42 days and weighing 200 to 230 g were randomly assigned to a control group (n = 20), which received distilled water, and an experimental group (n = ...
Pasquet Florian - - 2012
Abstract Purpose: To examine the relation between uveitis and common variable immunodeficiency (CVID). Methods: Retrospective analysis of patients included in the French DEFI cohort of adults with CVID and of patients identified by reviewing the literature. Results: Four patients were identified in the DEFI study (frequency of uveitis: 1.6%). The ...
Taskin Fusun - - 2012
PURPOSE.: To describe the sonographic (US) features associated with ultrasonography BI-RADS category 4 lesions that have a benign histopathological outcome. METHODS.: One hundred seventy-two histopathologically proven benign lesions in 169 patients, which had been classified as BI-RADS category 4 with ultrasonography, were retrospectively evaluated. Ultrasonography and histopathology findings were analyzed. ...
Nakayama-Ichiyama Shoko - - 2012
Abstract For differentiating reactive plasmacytosis from clonal plasma cell neoplasms such as plasma cell myeloma (PCM), it is important to determine the expression of the cytoplasmic light chain accurately. Through retrospective analysis, we studied the cytoplasmic kappa/lambda ratio of CD138-positive plasma cells in bone marrow from 50 PCM patients and ...
Almeida Rodrigo C - - 2012
BACKGROUND: Celiac disease is an autoimmune disorder that occurs in genetically susceptible individuals in whom the ingestion of dietary gluten induces intestinal mucosa inflammation. Previous studies suggest that celiac disease may either be very rare or underdiagnosed in African and/or African-derived population. AIM: Determine the prevalence of celiac disease in ...
Harp Eric - - 2012
Granular cell tumor rarely occurs in the thyroid. This case report describes the cytologic features of a granular cell tumor seen in a fine needle aspirate obtained from a 27-year-old woman with a gradually enlarging thyroid nodule. The aspirate showed single as well as syncytial clusters of cells with abundant ...
Kohout Michal - - 2012
The synthesis, ab initio calculations, and a comparative nuclear magnetic resonance study of a novel chiral mefloquine-based selector (SO) are presented. On a series of variously N-acyl protected leucine selectands (SAs), a feasibility study of mefloquine carbamate as a basic chiral solvating agent, and potential fluorophilic high-performance liquid chromatography selector ...
Wang Nan - - 2012
Catecholamine-containing small dense core granules (SDCGs, vesicular diameter of ∼100 nm) are prominent in carotid glomus (chemosensory) cells and some neurons, but the release kinetics from individual SDCGs has not been studied in detail. In this study, we compared the amperometric signals from glomus cells with those from adrenal chromaffin cells, ...
Hoda Rana S - - 2012
Liquid-based preparations (LBPs) have largely replaced conventional Papanicolaou smears (CPS) for cervical samples in the United States and in many other industrialized countries. The two FDA-approved LBP currently in use include ThinPrep (TP), (Hologic Inc., Bedford, MA) and SurePath (SP), (BD Diagnostic, Burlington, NC). Split-sample and direct-to-vial studies have shown ...
Turrell Gavin - - 2012
Introduction and Aims. Individual smokers from disadvantaged backgrounds are less likely to quit, which contributes to widening inequalities in smoking. Residents of disadvantaged neighbourhoods are more likely to smoke, and neighbourhood inequalities in smoking may also be widening because of neighbourhood differences in rates of cessation. This study examined the ...
Kim-Fine Shunaha - - 2012
Abstract Objectives: To establish gender-specific differences in maternal and fetal immune response in healthy human fetuses at term. Methods: Forty-five women with elective caesarean sections for uncomplicated singleton pregnancies were recruited for two studies. Using a Multiplex Biomarker Immunoassay system, un-stimulated maternal and fetal plasma concentrations of IL-1β, IL-1ra, IL-6, ...
Grangeon M - - 2012
Study design:A case study.Objective:The aim was to investigate whether motor imagery (MI) could be successfully incorporated into conventional therapy among individuals with spinal cord injury (SCI) to improve upper limb (UL) function.Setting:The Physical Medicine and Rehabilitation Unit at the Henry Gabrielle Hospital in Lyon, France.Methods:The participant was an individual with ...
Hara E S - - 2012
Summary  Occlusal dysesthesia refers to a persistent complaint of uncomfortable bite sensation with no obvious occlusal discrepancy. This systematic review aimed to draw a picture of such patients, to present an agreement of previously reported diagnostic criteria and to analyse the evidence level of the recommended management approaches. An electronic ...
Su Yu - - 2012
Abstract Although it is believed that altered conformations exposing cryptic regions are intermediary and critical steps in the mechanism of transthyretin (TTR) amyloid formation, no effective therapy targeting this step is available. In this study, to establish the antibody therapy for familial amyloidotic polyneuropathy (FAP), we generated a monoclonal anti-TTR ...
Ten Berge F - - 2012
Summary  The analysis of microwear patterns, including scratch types and widths, has enabled reconstruction of the dietary habits and lifestyles of prehistoric and modern humans. The aim of this in vitro study was to determine whether an assessment of microwear features of experimental scratches placed on enamel, perpendicularly to the ...
Anstice Nicola - - 2012
Background:  Limited data are available on the causes of visual impairment in preschool children in New Zealand. We aimed to review demographic and visual parameters in children referred to the Ophthalmology Department, Manukau Super Clinic from vision screening programs in South Auckland. Methods:  Retrospective medical record review of 131 children, ...
Caldwell Diana H - - 2012
Background: Individuals entering substance abuse treatment are at elevated risk for HIV infection, and clinicians must generally rely on patient self-report to gauge their involvement in risk behaviors. Strategies to improve accurate reporting of personally sensitive or stigmatizing risk behaviors are needed. Objective: This study compared computerized and face-to-face interview ...
Staver A Carla - - 2012
Ecology Letters (2012) ABSTRACT: The role of top-down factors like herbivory and fire in structuring species' niches, even in disturbance-dependent biomes like savanna, remains poorly understood. Interactions between herbivory and fire may set up a potential tradeoff axis, along which unique adaptations contribute to structuring communities and determining species distributions. ...
Ioannou Christos - - 2012
OBJECTIVE: Rendered three-dimensional images of the fetal cranial vault permit the identification of sutures and measurement of the fontanelle surface area. The objective of this study was to establish the feasibility and repeatability of sphenoidal fontanelle area measurement. METHOD: Head volumes were obtained using the biparietal diameter as the reference ...
- - 2012
The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the articles related to pericardial and epicardial disease that ...
Scerpa Maria Cristina - - 2012
Background aims. Immunomagnetic cell selection (ICS) of CD34(+) cells is being used increasingly in allogeneic transplantation in order to reduce T-cell quantity. The aim of this study was to evaluate an automated washing protocol before immunomagnetic selection. Methods. The automated method was compared with a conventional washing procedure. In the ...
Wong C C M - - 2012
Background and Aim:  Intrarectal administration of mouse cathelin-related antimicrobial peptide (mCRAMP) reduced intestinal inflammation in mice. In the current study, we examined whether mCRAMP-transformed Lactococcus lactis given orally attained similar protective effects. Method:  mCRAMP was produced and secreted from the transformed L. lactis. Murine colitis was induced by ingestion of ...
Lee Tsung-Ming - - 2012
Sympathetic activities are elevated in the central sympathetic nervous systems of hypertensive animals but it is not known if sympathetic innervation is also elevated in the heart. Sympathetic hyperresponsiveness in hypertension may result from oxidative stress. The aim of this study was to investigate sympathetic hyperinnervation in deoxycorticosterone acetate (DOCA)-salt ...
Campana L G - - 2012
BACKGROUND: The aim of the study was to determine predictive factors for effectiveness, toxicity and local disease control in patients with malignant melanoma treated with bleomycin-based electrochemotherapy (ECT). METHODS: Electrochemotherapy was offered to patients with superficially disseminated melanoma metastases unsuitable for resection and unresponsive to chemotherapy. RESULTS: Eighty-five patients were ...
Axente Marian - - 2012
The purpose of this study was to investigate the increase in cell kill that can be achieved by tumor irradiation with heterogeneous dose distributions targeting hypoxic regions that can be visualized with non-invasive imaging. Starting with a heterogeneous distribution of microvessels, a microscopic two-dimensional model of tumor oxygenation was developed ...
Feldman B M - - 2012
Summary.  Severe haemophilia results in increased mortality and poorer quality of life. Factor prophylaxis leads to a more normal life, but is very costly; most of the cost is due to the high cost of replacement factor. Despite its high cost, factor prophylaxis has been adopted throughout the developed world ...
Malwitz Mark M - - 2012
The remarkable, vapor-induced transformation of the yellow polymorphs of [(C6H11NC)2AuI](AsF6) and [(C6H11NC)2AuI](PF6) into the colorless forms are reported along with related studies of the crystallization of these polymorphs. Although the interconversion of these polymorphs is produced by vapor exposure, molecules of the vapor are not incorporated into the crystals. Thus, ...
Pan Qiuwei - - 2012
Liver transplantation is an effective treatment for end-stage liver disease that is attributable to chronic HCV infection. However, long-term outcomes are compromised by universal virological recurrence in the graft. Reinfection that occurs after transplantation has increased resistance to current interferon-based antiviral therapy and often leads to accelerated development of cirrhosis. ...
Klumpp Dorothee - - 2012
Nanofiber scaffolds have proven their various advantages for tissue engineering and have been analyzed extensively. However, to date the three-dimensional pattern of vascularization inside nanofibrous scaffolds is unknown. This study introduces a novel method to visualize and quantify vascularization of electrospun nanofibrous PCL/collagen scaffolds in 3D in vivo. Randomly spun ...
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