Search Results
Results 251 - 300 of 2656
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Endo Yoshiro - - 2012
Prevalence of equine gastric ulcer syndrome in 85 young Thoroughbreds was investigated. The presence of gastric ulcers was confirmed in 27.1% (23/85) of the horses by endoscopic examination. For 62 horses without gastric ulcers were allocated randomly to either the treated group (31 horses) or sham-dosed control group (31 horses) ...
Täng Margareta Scharin - - 2012
Background: Regional myocardial deformation patterns are important in a variety of cardiac diseases, including stress-induced cardiomyopathy. Velocity-vector-based imaging is a speckle-tracking echocardiography (STE)-based algorithm that has been shown to allow in-depth cardiac phenotyping in humans. Regional posterior wall myocardial dysfunction occurs during severe isoprenaline stress in mice. We have previously ...
McKee Kristopher J - - 2012
Total internal reflection (TIR) Raman and reflectivity spectra were collected for non-resonant analytes as a function of incident angle at sapphire or sapphire/smooth 50 nm gold interfaces using 785 nm excitation. For both interfaces, the Raman signal as a function of incident angle is well-modeled by the calculated interfacial mean ...
Sohn Won - - 2012
Background:  The widely accepted range of upper limits of normal ALT levels (ULN < 40 U/L) was recently challenged by several reports. And both ALT and AST are commonly used as surrogate marker of liver disease, almost all studies related aminotransferase activity limited to ALT activity. We investigated not only ...
Bostick Geoff P - - 2012
Purpose: To use quantitative data characterizing whiplash-associated disorder (WAD)-related pain beliefs over time to develop qualitative analysis exploring experiences informing these beliefs. Method: A mixed-method design was used. Quantitative and qualitative data were collected concurrently at baseline and 3 and 6 months postmotor vehicle collision. WAD-related pain beliefs were quantitatively ...
Ishikawa T - - 2012
The temperature and polarization dependence of the optical reflectivity  spectra of a quasi-one-dimensional 1/4-filled band system, (DMEDO-EBDT)(2)PF(6), have been investigated. We observed clear anisotropy in the electronic structures corresponding to the anisotropic transport properties. The appearance of a charge gap (E(g) > 0.1 eV) and transfer of the spectral weight accompanied by the ...
Xing Zhitao - - 2012
New coumarin-based chiral thiourea sensor was found to be an enantioselective fluorescent chemosensor for N-Boc-protected proline. The chiral sensor shows lower background fluorescence, and higher fluorescence enhancement with 18 nm blue shifts. Job plot analysis result indicates that sensor can form a 1 : 1 stoichiometric complex and it could be used ...
Tomita Toshihiko - - 2012
Background and Aims:  Proton pump inhibitors (PPIs) are generally used to prevent delayed bleeding after endoscopic submucosal dissection (ESD) and to heal the artificial ulcers. However, it remains controversial whether PPIs or histamine-2 receptor antagonists (H(2) RAs) are more effective in preventing delayed bleeding after ESD. We prospectively compared the ...
Wong H S - - 2012
We present an in-depth study of the myriad atomically resolved patterns observed on graphite using the scanning tunnelling microscope (STM) over the past three decades. Through the use of highly resolved atomic resolution images, we demonstrate how the interactions between the different graphene layers comprising graphite affect the local surface ...
Gruner Christiane - - 2012
Objectives: Anderson-Fabry disease (AFD) is a lysosomal storage disease, which can involve the heart, mimicking hypertrophic cardiomyopathy (HCM). The underlying mechanism of disease in AFD is an infiltrative, diffuse process, whereas HCM is a primary heart muscle condition with patchy distribution, which may prompt differences in myocardial mechanics. The aim ...
Ky Bonnie - - 2012
Background: The left ventricle (LV) undergoes significant architectural remodeling in heart failure (HF). However, the fundamental associations between cardiac function and LV size and performance have not been thoroughly characterized in this population. We sought to define the adaptive remodeling that occurs in chronic human HF through the detailed analyses ...
Bernardino N R - - 2012
Using a square-gradient density functional model we test the prediction that the filling transition for a fluid in a wedge geometry changes from continuous to first-order as the wedge becomes more acute. Our numerical findings confirm such a change of order, but the value of the tilt angle at which ...
Sorel Sophie - - 2012
We have characterized the optoelectrical properties of networks of silver nanowires as a function of nanowire dimension by measuring transmittance (T) and sheet resistance (R(s)) for a large number of networks of different thicknesses fabricated from wires of different diameters (D) and lengths (L). We have analysed these data using ...
Zerbino D R - - 2012
As genomic sequencing projects attempt ever more ambitious integration of genetic, molecular, and phenotypic information, a specialization of genomics has emerged, embodied in the subdiscipline of computational genomics. Models inherited from population genetics, phylogenetics, and human disease genetics merge with those from graph theory, statistics, signal processing, and computer science ...
Himaki Takehiro - - 2012
The objective of this study was to examine the effect of postactivation treatment with latrunculin A (LatA), an actin polymerization inhibitor, on in vitro and in vivo development of somatic cell nuclear transfer (SCNT) embryos derived from kidney fibroblasts of an Clawn miniature boar (12 years old). After electric activation, ...
Feng Xuesong - - 2012
Epstein-Barr virus (EBV) was considered as a major factor that causes nasopharyngeal carcinoma (NPC), which is one of the sneakiest cancers frequently occurred in Southeast Asia and southern China Apoptosis and pro-apoptotic signals have been studies for decades. However, few researches have extended the prevailing view of EBV to its ...
Kirsten Lars - - 2012
The investigation of lung dynamics on alveolar scale is crucial for the understanding and treatment of lung diseases, such as acute lung injury and ventilator induced lung injury, and to promote the development of protective ventilation strategies. One approach to this is the establishment of numerical simulations of lung tissue ...
Li Wenbo - - 2012
A series of lanthanide amide complexes supported by bridged bis(amidinate) ligand L, LLnNHAr(1)(DME) (L = [Me(3)SiNC(Ph)N(CH(2))(3)NC(Ph)NSiMe(3)], Ar(1) = 2,6-(i)Pr(2)C(6)H(3), DME = dimethoxyethane, Ln = Y (), Pr (), Nd (), Gd (), Yb ()), [Yb(μ(2)-NHPh)](2)(μ(2)-L)(2) () and [LYb](2)(μ(2)-NHAr(2))(2) () (Ar(2) = (o-OMe)C(6)H(4)), were synthesized by reaction of LLnCl(THF)(2) with the ...
Hodgkinson James T - - 2012
Many species of bacteria employ a mechanism of intercellular communication known as quorum sensing which is mediated by small diffusible signalling molecules termed autoinducers. The most common class of autoinducer used by Gram-negative bacteria are N-acylated-l-homoserine lactones (AHLs). Pseudomonas aeruginosa is a clinically important bacterium which is known to use ...
Schievenbusch Stephanie - - 2012
We have previously identified Neighbor of Punc E 11 (Nope) as a specific cell surface marker of stem/progenitor cells in the murine fetal liver that is also expressed in hepatocellular carcinoma. Here, we focus on the differential expression pattern of Nope during fetal and postnatal liver development as well as ...
Xu-Monette Zijun Y - - 2012
The TP53 (p53) protein is a well-known tumor suppressor that plays a crucial role in maintaining genome stability under various cellular stresses. Loss of TP53 causes lymphomagenesis in mouse models and/or promotes tumor progression. However, the prognostic significance of TP53 has been inconsistent in human cancers including malignant lymphoma. In ...
Ahn Seung-Eon - - 2012
The photoresponse characteristics of metal-oxide (MeO) semiconductor photosensors have been studied. Compared to the amorphous-Si-based photo-TFT, the MeO photo-TFT demonstrates superior EQE and responsivity. However, due to its inherent slow recovery to the dark state after the illumination is stopped, a unique sensing scheme suitable for the high-speed array operation ...
Lake Benjamin R M - - 2012
An electrochemical approach for the preparation of copper(i) N-heterocyclic carbene complexes has been developed to include a diverse range of ligand precursors. Importantly, the method is effective for a ligand precursor that contains several acidic protons and for which traditional methods of carbene formation are not suitable.
Mizutani Masato - - 2012
Self-degradable antimicrobial copolymers bearing cationic side chains and main-chain ester linkages were synthesized using the simultaneous chain- and step-growth radical polymerization of t-butyl acrylate and 3-butenyl 2-chloropropionate, followed by the transformation of t-butyl groups into primary ammonium salts. We prepared a series of copolymers with different structural features in terms ...
Ma Huipeng - - 2012
Mesenchymal stem cells (MSCs) are the progenitors of stromal cells, which have been found to interact with cancer cells and represent an important target for cancer therapies. Salivary gland cancer is an aggressive malignant epithelial tumor and can easily disseminate to distant sites in vivo. In this work, we probed ...
Miyajima Daigo - - 2012
Ferroelectric liquid crystals are materials that have a remnant and electrically invertible polar order. Columnar liquid crystals with a ferroelectric nature have potential use in ultrahigh-density memory devices, if electrical polarization occurs along the columnar axis. However, columnar liquid crystals having an axial nonzero polarization at zero electric field and ...
Suto Jun-Ichi - - 2012
Growth deficit (gd) is a recessive mutation that occurs spontaneously in the inbred NC/Sgn mouse strain. Because homozygotes (gd/gd) of both sexes are sterile, they must be produced by mating putative heterozygous carriers (+/gd) whose phenotypes are essentially the same as those of wild-type +/+ mice. The objectives of this ...
Dreyfus Tom - - 2012
We introduce Toleranced Models (TOM), a generic and versatile framework meant to handle models of macro-molecular assemblies featuring uncertainties on the shapes and the positions of proteins. A TOM being a continuum of nested shapes, the inner (resp. outer) ones representing high (low) confidence regions, we present topological and geometric ...
Tang Hai-Ling - - 2012
Background and Aim:  ARHI is a maternally imprinted tumor suppressor gene. ARHI protein is widely expressed in many types of human tissues; however, its expression is frequently reduced or absent in various tumors and plays tumor suppressor role in vitro study. In this study, we investigated the expression level of ...
Evers Elisabeth Anna - - 2012
Previous studies showed that functional connectivity (FC) within resting state (RS) networks is modulated by previous experience. In this study the effects of sustained cognitive performance on subsequent RS FC were investigated in healthy young (25 - 30 years; n=15) and middle-aged (50 - 60 years; n=14) male schoolteachers. Participants ...
Porrati F - - 2012
CoPt-C binary alloys have been fabricated by focused-electron-beam-induced deposition by the simultaneous use of Co(2)(CO)(8) and (CH(3))(3)CH(3)C(5)H(4)Pt as precursor gases. The alloys are made of CoPt nanoparticles embedded in a carbonaceous matrix. TEM investigations show that as-grown samples are in an amorphous phase. By means of a room temperature low-energy ...
Ding M - - 2012
The AND gate functions such that when all inputs are activated the downstream gene will be transcribed and it is off otherwise. To accomplish optimal and targeted gene therapy in solid tumor patients, we have constructed an AND gate genetic circuit and investigated whether it could be activated by low-dose ...
Morelli Luis G - - 2012
Computational approaches are breaking new ground in understanding how embryos form. Here, we discuss recent studies that couple precise measurements in the embryo with appropriately matched modeling and computational methods to investigate classic embryonic patterning strategies. We include signaling gradients, activator-inhibitor systems, and coupled oscillators, as well as emerging paradigms ...
Sans Susana - - 2012
Aims. To investigate the relationship of body mass index and serum adipokines with incidence of diabetes in men. Material and methods. Ten-year cohort study of a random population sample of 1011 men aged 35-69 years from the MONICA-Catalonia survey (1986-1988). WHO-MONICA protocol and the US Hispanic NHANES diabetes questionnaire were ...
Fabregat Georgina - - 2012
The morphology of poly(N-cyanoethylpyrrole) has been controlled through the polymerization process. This polymer has been prepared by anodic polymerization, chemical oxidative polymerization in emulsion medium, and layer-by-layer templating polymerization. Anodic polymerization using LiClO(4) as supporting electrolyte provides compact films, in which the oxidation degree is controlled through the thickness, useful ...
Suh Hye-Young - - 2012
Post-translational modification by SUMO can be reversed by SENPs, the first known class of deSUMOylase. Recently, we identified a new deSUMOylating enzyme DeSI-1, which is distinct from SENPs and belongs to the putative deubiquitinating isopeptidase PPPDE superfamily. Herein, we report the crystal structure of DeSI-1, revealing that this enzyme forms ...
Zhang Jianyuan - - 2012
The nanoscale parameters of metal lattice have crucial influence on macroscopic properties of materials. Herein we provide a detailed study on the size and shape of isolated yttrium carbide clusters in different fullerene cages. A family of diyttrium endohedral metallofullerenes with the general formula of Y2C2n (n=40-59) are reported. The ...
Denson Linley A - - 2012
Scand J Caring Sci; 2012 Discharge-planning for long-term care needs: the values and priorities of older people, their younger relatives and health professionals Discharge-planning decisions about long-term care (LTC) can be difficult and distressing for older people, families and discharge-planning health professionals. Retrospective research suggests that despite good intentions and ...
He Shijiang - - 2012
We have developed a SERS-active substrate based on gold nanoparticles-decorated CVD-growth graphene and used it for multiplexing detection of DNA. Due to the combination of gold nanoparticles and graphene, the Raman signals of dye were dramatically enhanced by this novel substrate. With the gold nanoparticles, DNA capture probes could be ...
Shin Hye Sun - - 2012
Background/Aims:  Little information is available about the antiviral efficacy of lamivudine (LAM) and entecavir (ETV) in patients with hepatitis B virus (HBV)-related advanced hepatocellular carcinoma (HCC). Thus, we compared the antiviral efficacy of LAM and ETV in these patients. Methods:  The medical records of 134 antiviral therapy-naïve patients with HBV-related ...
Mierke Claudia T - - 2012
Most cancer-related deaths are caused by the ability of cancer cells to metastasize. This process includes the dissemination of cancer cells from the primary tumor side and their migration to targeted organ sites. During the migration of cancer cells through the connective tissue microenvironment, which consists of endothelial cells and ...
Rubio-Guerra Alberto Francisco - - 2012
Endothelial dysfunction is a common feature in type-2 diabetic patients and is associated with inflammation, increased levels of circulating soluble adhesion molecules and atherosclerosis. Insufficiency of tetrahydrobiopterin leads to uncoupling of the nitric oxide synthase enzyme an endothelial dysfunction. The aim of this study was to evaluate if there is ...
Sevinc Ok Ebru - - 2012
It is anticipated that oxidized low-density lipoprotein (oxLDL) and anti-oxLDL are associated with atherosclerosis and mortality. However, data on this issue are controversial and limited. We aimed to investigate the effect of these two markers on the extent and progression of atherosclerosis and mortality in a group of hemodialysis patients. ...
Pellegrinelli J M - - 2012
OBJECTIVE: Primary fetal pleural effusions are rare. If severe, thoracoamniotic shunting is needed. Our objective was to study the management and outcomes of pleural effusions in our unit. METHODS: Retrospective analysis of primary fetal hydrothorax between 1991 and 2010. RESULTS: Of 41 cases, 23 (56%) were hydropic, and 27 (66%) ...
Jackson Belinda D - - 2012
Background and Aims:  Unexplained liver injury including fibrosis and portal hypertension has rarely been reported among patients with HIV in the absence of co-infection with hepatitis B (HBV) or hepatitis C (HCV). We describe a series of HIV mono-infected patients with evidence of non-cirrhotic portal hypertension. Methods:  HIV-infected patients with ...
Kozai Keisuke - - 2012
Although circulating progesterone (P(4)) levels tend to change with the season, little is known about the seasonal changes of P(4) synthesis-related proteins in the corpus luteum (CL) of mares. To examine these changes, seventy-four ovaries containing a CL were collected from Anglo-Norman mares at a local abattoir in Kumamoto, Japan ...
Skjolding Anders Daehli - - 2012
Aims:  Aqua¬porin-4 is the most abundant cellular water channel in brain and could be a molecular basis for a cerebrospinal fluid absorption route additional to the arachnoid villi. In the search for "alternative" cerebrospinal fluid absorption pathways it is important to compare experimental findings to human pathophysiology. This study compares ...
Chatuphonprasert Waranya - - 2012
The effects of six Thai fruits, namely banana, guava, mangosteen, pineapple, ripe mango and ripe papaya, on cytochrome P450 (P450) activities were investigated. The median inhibitory concentrations (IC(50) ) of each of the fruit juices on CYP1A1, CYP1A2, CYP2E1 and CYP3A11 activities were determined. Pineapple juice showed the strongest inhibitory ...
Lee In Hye - - 2012
Withdrawal of nutrients triggers an exit from the cell division cycle, the induction of autophagy, and eventually the activation of cell death pathways. The relation, if any, among these events is not well characterized. We found that starved mouse embryonic fibroblasts lacking the essential autophagy gene product Atg7 failed to ...
Modak P - - 2012
The ground state geometry and electronic structure of various 4d transition metal (TM) atom (Y, Zr, Nb and Mo) decorated single wall carbon nanotubes (SWCNTs) are obtained using density functional theory and the projector augmented wave (PAW) method. We found a systematic change in the adsorption site of the transition ...
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