Search Results
Results 301 - 350 of 2770
< 2 3 4 5 6 7 8 9 10 11 12 >
Forsman A K - - 2012
Objective: To study the association between structural and cognitive aspects of social capital and depression among older adults in two Nordic regions. Method: Data were retrieved from a postal survey targeting older adults aged 65, 70, 75 and 80 years (N = 6 838, response rate = 64%) residing in the Västerbotten region (Sweden), and ...
Eid Tore T Department of Laboratory Medicine, Yale University School of Medicine, 330 Cedar Street, P.O. Box 208035, New Haven, CT 06520-8035, USA. - - 2012
Glutamine synthetase (GS, E.C. 6.3.1.2) is a ubiquitous and highly compartmentalized enzyme that is critically involved in several metabolic pathways in the brain, including the glutamine-glutamate-GABA cycle and detoxification of ammonia. GS is normally localized to the cytoplasm of most astrocytes, with elevated concentrations of the enzyme being present in ...
Rapoport J L - - 2012
The neurodevelopmental model of schizophrenia, which posits that the illness is the end state of abnormal neurodevelopmental processes that started years before the illness onset, is widely accepted, and has long been dominant for childhood-onset neuropsychiatric disorders. This selective review updates our 2005 review of recent studies that have impacted, ...
de Kok Stefan - - 2012
Plasma membrane H(+)-ATPase isoforms with increased H(+)/ATP ratios represent a desirable asset in yeast metabolic engineering. In vivo proton coupling of two previously reported Pma1p isoforms (Ser800Ala, Glu803Gln) with increased in vitro H(+)/ATP stoichiometries was analysed by measuring biomass yields of anaerobic maltose-limited chemostat cultures expressing only the different PMA1 ...
Sathyadevi Palanisamy - - 2012
Two new copper(i) hydrazone complexes have been synthesised from bivalent copper precursor [CuCl(2)(PPh(3))(2)] and ferrocene containing bidentate hydrazone ligands HL(1) () or HL(2) (). Based on the elemental analyses and spectroscopic data, the complexes are best formulated as [CuL(1)(PPh(3))(2)] () and [CuL(2)(PPh(3))(2)] () of the monovalent copper ion. Solid state ...
Summers deLuca Leslie - - 2012
Members of the tumour necrosis factor (TNF) superfamily have been implicated in a wide range of biological functions, and their expression by cells of the immune system makes them appealing targets for immunomodulation. One common theme for TNF superfamily members is their coordinated expression at the interface between antigen-specific T ...
Frieden L - - 2012
Objectives:This paper reviews the literature pertaining to the employment of people who experience spinal cord injury (SCI) in the United States and recommending future research.Methods:The literature was reviewed with search terms such as SCI, employment, working from home and telework using databases in EBSCO, including Academic Search Complete and the ...
Ghoshal Tandra - - 2012
Highly dense hexagonal ordered arrays of superparamagnetic iron oxides nanodots are fabricated by a simple and cost-effective route. Spectroscopic, microscopic and magnetic measurements show that the nanodots have uniform size, shape and their placement mimics the original self-assembled block copolymer pattern. The nanodots show good thermal stability and strong adherence ...
Schnüriger Beat - - 2012
BACKGROUND: The predictive factors to regain a heartbeat following emergency department resuscitative thoracotomy (EDT) for trauma are poorly understood. The objective of the present study was to prospectively assess the electrolyte profile, coagulation parameters, and acid-base status from intracardiac blood samples in trauma patients subjected to open cardiopulmonary resuscitation (CPR) ...
Wang Lisu - - 2012
Chronic arsenic exposure has been linked to an increased risk of vascular diseases. To clarify the molecular mechanisms through which arsenic causes injuries to blood vessels, we analyzed the effects of arsenic trioxide on the cytotoxicity, intracellular reactive oxygen species (ROS), the expression of related genes, and signaling pathways involved ...
da Silva Ana Raquel Araújo AR Post-Graduate Program of Biotechnology, State University of Ceará, Fortaleza, CE, - - 2012
The leaves of Spondias tuberosa Arr. Cam. (Anacardiaceae) and Spondias mombin L. have been traditionally used for medicinal purposes. Some studies reveal their antibacterial, antimicrobial, and antiviral properties. Determine the chemical composition, antioxidant, and antimicrobial activities of Spondias species to justify its ethnopharmacological use. Spondias species extracts were prepared with ...
Raap Ulrike - - 2012
The oral mucosa is constantly exposed to a large number of potentially irritating and sensitizing dental materials. Dental materials used for fillings and fixed or removable replacements must have a good biocompatibility. Metals including palladium are used in alloys for the production of the core of crowns, onto which porcelain ...
Tonner Ralf - - 2012
In an effort to understand the chemical factors that stabilize dianions, experimental and theoretical studies on the stability of the tartrate dianion were performed. Quantum chemical calculations at the coupled cluster level reveal only a metastable state with a possible decomposition pathway (O2C-CH(OH)-CH(OH)-CO2)2- -> (O2C-CH(OH)-CH(OH))•- + CO2 + e- explaining ...
Balić Davor - - 2012
To investigate the degree of genetic variability of bovine leukemia virus (BLV) strains circulating in Croatia, 29 isolates from the six largest dairy farms were examined by PCR for a segment of the gp51 env gene, followed by DNA sequencing and phylogenetic analysis. The nucleotide sequences were compared with other ...
Rahir Gwendoline - - 2012
There is ample evidence that the presence of tumor-infiltrating T lymphocytes is associated with a favorable prognostic in patients. These observations suggest that a limiting step to immune resistance and immunotherapy could be the capacity of tumor-specific T cells to reach tumor bed. In this article, we review some factors ...
Martineau Charlotte - - 2012
We present in this paper the structure resolution of a fluorinated inorganic-organic compound-Zn(3)Al(2)F(12)·[HAmTAZ](6)-by SMARTER crystallography, i.e. by combining powder X-ray diffraction crystallography, NMR crystallography and chemical modelling of crystal (structure optimization and NMR parameter calculations). Such an approach is of particular interest for this class of fluorinated inorganic-organic compound materials ...
Theocharis Stamatios - - 2012
PURPOSE: Focal adhesion kinase (FAK) and Src are protein tyrosine kinases, localized in the focal adhesions, which, upon activation interacts each other, regulate several cellular signaling pathways implicated in malignant transformation and disease progression. The present study aimed to evaluate the clinical significance of FAK and Src protein expression in ...
Shan Changsheng - - 2012
A large quantity of highly conductive graphene was prepared by a novel CVD method with nickel powder as a template and PMMA as carbon source. With Pt as a model, PtNP-modified graphene showed much better electrocatalytic ability for O(2) and methanol than PtNP-reduced graphene oxide (RGO) and commercial Pt/C, showing ...
Manna Prasenjit - - 2012
Abstract In this review article, we describe the most recent development of the beneficial effect of arjunolic acid (AA) in reducing type 1 diabetic pathophysiology. Diabetic mellitus is a serious and growing health problem worldwide. Increasing evidence suggest that oxidative stress plays a pivotal role in the pathogenesis of diabetes ...
Tabuchi Masahiro - - 2012
18β-Glycyrrhetinic acid (GA) is a major metabolite of glycyrrhizin (GL), which is one of the components of glycyrrhiza root, a constituent herb of the traditional Japanese medicine yokukansan. It is well known that most GL is metabolized to GA in the intestine by bacteria. A previous in vitro study using ...
Groen Reinou S - - 2012
BACKGROUND: A first step toward improving surgical care in many low and middle income countries is to document the need. To facilitate the collection and analysis of surgical capacity data and measure changes over time, Surgeons OverSeas (SOS) developed a tool and index based on personnel, infrastructure, procedures, equipment, and ...
Müllersdorf Maria - - 2012
The aim of this study was to describe the prevalence of creative activities in occupational therapy in Sweden and how often Swedish occupational therapists use creative activities as a means of intervention. A web-mail survey was sent to 2975 Swedish occupational therapists working in health care at regional, county council ...
Zhang Minghui - - 2012
An artificial nanofluidic diode system is prepared, mimicking the light-gated and pH-tunable ion channels that play an important role in life sciences. When UV light is off, the nanochannel is in the closed state, analogous to a resistance. Under UV light irradiation and at pH 7, the current flows from ...
Kobashigawa Yoshihiro - - 2012
Pseudo contact shifts (PCSs) induced by paramagnetic lanthanide ions fixed in a protein frame provide long-range distance and angular information, and are valuable for the structure determination of protein-protein and protein-ligand complexes. We have been developing a lanthanide-binding peptide tag (hereafter LBT) anchored at two points via a peptide bond ...
Erikstad Helge-André - - 2012
Methane monooxygenases (MMOs) are oxygen-dependent enzymes that catalyze the oxidation of methane to methanol in the methanotrophic bacteria. The thermoacidophilic verrucomicrobial methanotroph 'Methylacidiphilum kamchatkense' Kam1 contains three complete and phylogenetically distinct copies of the pmoCAB gene cluster apparently organized as operons, each encoding all three subunits of particulate MMO (pMMO), ...
Nelis Sharon M - - 2012
Objectives: The process of developing and living with dementia may activate attachment feelings and behaviours in people with dementia (PwD) and their carers. By obtaining information from both PwD and carer, we aimed to provide information on the nature and concordance of attachment patterns within the dyad and to examine ...
Stöllberger Claudia - - 2012
Parasympathomimetics, immunosuppression and plasmapheresis have considerably improved management and prognosis of myasthenia gravis. Side effects of these measures, however, may complicate the course of the disease. In a 66-year-old male with myasthenia gravis and lower back pain, blood cultures, echocardiography and magnetic resonance imaging led to the diagnosis of endocarditis ...
Zengin Halit - - 2012
In this study, we investigated the morphometric and histological alterations of the aorta, brachial, and femoral arteries in 4- and 20-week-old rats that were prenatally exposed to diclofenac sodium (DS). For this purpose, pregnant rats were divided into three groups: control, saline injected, and drug treated. Beginning from day 5 ...
Zeng Huan - - 2012
The preparation of magnetic molecularly imprinted polymers (MMIPs) which can be used for the separation and purification of rutin from Chinese medicinal plants has been proposed. By applying the improved co-precipitation method, magnetic Fe(3)O(4) particles were easily prepared, followed by the modification of TEOS and functionalization with -CH[double bond, length ...
Shen Jian-Min - - 2012
We developed a novel chitosan-based luminescent/magnetic hybrid nanoparticles with folate-conjugated tetrapeptide composites (CLMNPs-tetrapeptide-FA) by conjugation in situ. First, chitosan, CdTe quantum dots (QDs) and superparamagnetic iron oxide were directly gelated into ternary hybrid nanogels. Subsequently, tetrapeptides (GFFG and LGPV) and folate were conjugated orderly to the hybrid nanoparticles. The morphology, ...
Ferraro Simona - - 2012
Background. Fibrinogen elevation is associated with a worse prognosis in patients with acute coronary syndrome (ACS). The aim of the present study was to assess the prognostic value of increased fibrinogen concentrations in ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (PCI). Methods. A total of 428 ...
Braak Breg - - 2012
Repeated exposure to stress leads to mast cell degranulation, microscopic inflammation, and subsequent visceral hypersensitivity in animal models. To what extent this pathophysiological pathway has a role in patients with the irritable bowel syndrome (IBS) has not been properly investigated. The objective of this study was to assess the relationship ...
Wang Yuji - - 2012
To discover whether novel anti-tumor platinum agents are capable of selectively accumulating in tumor tissue, three novel potassium N-[(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxylhex-1-yl]-l-amino acid dichloroplatinates(II) were prepared. At a dose of 1.67 μmol kg(-1) the in vivo anti-tumor potencies of two of the compounds were higher than that of oxaliplatin. The mortality analysis indicated ...
Wu Xiaohong - - 2012
The low-shrink Silorane-based composite could bond effectively to bone and showed the potential be used as a bone cement. Bone organ culture maintains the anatomical order, natural cell-to-cell and cell-to-matrix relationship. The purpose of this study was to evaluate the responses of bone cells to a Silorane-based composite which was ...
Coll-De-Tuero Gabriel - - 2012
Background. The aim is to evaluate whether cardiovascular (CV) risk stratification in newly diagnosed hypertensive patients according to the European Society of Hypertension (ESH) guidelines, can predict the evolution of target organ damage (TOD) using routine examinations in clinical practice during 1 year. Methods. Prospective study of recently diagnosed untreated ...
Moore David J - - 2012
Leg exercise hemodynamics during single-leg knee extensions were compared among healthy groups of early perimenopausal (n = 15), late perimenopausal (n = 12), and early postmenopausal (n = 11) women. Femoral blood flow (FBF) and vascular conductance (FVC) at rest and during very light work rates (0 and 5 W) ...
Loh Owen - - 2012
Nanoelectromechanical devices exhibiting dramatically improved robustness through novel material selection are demonstrated. A unique combination of carbon nanotube active elements and conductive diamond-like carbon contact electrodes results in reliable switching performance not found in devices with ubiquitously-used metal thin film electrodes. This in turn represents a viable means to improve ...
Barik Amita - - 2012
We have developed a non-redundant protein-RNA docking benchmark dataset, which is derived from the available bound and unbound structures in the PDB involving polypeptide and nucleic acid chains. It consists of 9 unbound-unbound cases where both the protein and the RNA are available in the free form. The other 36 ...
Wu Hao Bin - - 2012
Anatase TiO(2) nanowires have been directly synthesized via a one-pot solvothermal approach. The curved nanowires with length of ca. 300 nm and diameter of ca. 10 nm are grown along the [101] direction and assembled into hierarchical structures. After annealing, the anatase TiO(2) nanowires perfectly retain the nanostructure, and manifest ...
Chamberlain Scott A - - 2012
Meta-analysis is increasingly used in ecology and evolutionary biology. Yet, in these fields this technique has an important limitation: phylogenetic non-independence exists among taxa, violating the statistical assumptions underlying traditional meta-analytic models. Recently, meta-analytical techniques incorporating phylogenetic information have been developed to address this issue. However, no syntheses have evaluated ...
Sulaiman Ahmad Hatim - - 2012
Objectives. The objectives of this study were to determine the efficacy and safety of aripiprazole for treatment of psychosis, retention and abstinence in patients with methamphetamine dependence. Methods. This was a double-blind study where 37 methamphetamine dependent patients with history of psychosis were randomly assigned to receive aripiprazole (5-10 mg ...
de Montferrand Caroline - - 2012
The magnetic behavior at room temperature of maghemite nanoparticles of variable sizes (from 7 to 20 nm) is compared using a conventional super quantum interference device (SQUID) and a recently patented technology, called MIAplex. The SQUID usually measures the magnetic response versus an applied magnetic field in a quasi-static mode ...
Korossy-Mruk Eva - - 2012
To study the influence of the central noradrenergic system on antinociceptive effects mediated by the CB(1)-receptor agonist methanandamide, intact rats were contrasted with rats in which noradrenergic nerves were largely destroyed shortly after birth with the neurotoxin DSP-4 [N-(-2-chloroethyl)-N-ethyl-2-bromobenzylamine (50 mg/kg sc × 2, P1 and P3); zimelidine (10 mg/kg sc, 30 min pretreatment, selective serotonin reuptake ...
Dettling Daniela S - - 2012
BACKGROUND: Patients undergoing oesophageal surgery have a high risk for post-operative complications including pulmonary infections. Recently, physical therapy has shifted from the post-operative to the pre-operative phase to diminish post-operative complications and to shorten hospital stay. The purpose of this pilot study was to investigate the feasibility and initial effectiveness ...
Otzen Marleen - - 2012
During budding of yeast cells peroxisomes are distributed over mother cell and bud, a process that involves the myosin motor protein Myo2p and the peroxisomal membrane protein Inp2p. Here we show that Pex19p, a peroxin implicated in targeting and complex formation of peroxisomal membrane proteins, also plays a role in ...
Abraham Suzanne - - 2012
Abstract Objective. Little is known about the symptoms of abdominal bloating and distension in women with eating disorders (EDs). This study aimed to explore the prevalence and predictors of these symptoms in patients with EDs, by examining correlations with functional gastrointestinal disorders (FGIDs) including pelvic floor symptoms and other clinical ...
Bajoria Atul A AA Department of Prosthodontics, Manipal College of Dental Sciences, Mangalore, Karnataka, India. - - 2012
Knowing how patients really feel after treatment is, very often, as relevant as the success rate of the conventional dentures and it can even be the measurement of masticatory function. This questionnaire survey aimed to analyse the satisfaction level and masticatory efficiency of patients treated with conventional complete dentures.   ...
Bares Martin - - 2012
Objective. This randomized, 6-week, open-label study compared efficacy of CAD and antidepressant monotherapies (ADM) that had been chosen according to clinical judgment of the attending psychiatrist. Methods. A total of 60 inpatients (intent-to-treat analysis) with depressive disorder (≥ 1 unsuccessful antidepressant treatment) were randomly assigned to the interventions. The responders who ...
Akiyama Haruhisa - - 2012
Sugar alcohol derivatives with multi azobenzene arms are photochemically and isothermally liquefied from a powdered solid upon irradiation with ultraviolet light at room temperature, and then solidified on irradiation with visible light, where the transition between solid and liquid are reversible. These compounds possess similar chemical structures to comb-like liquid ...
Gibson Peter R - - 2012
Recognition of food components that induce functional gut symptoms in patient's functional bowel disorders (FBD) has been challenging. Food directly or indirectly provides considerable afferent input into the enteric nervous system. There is an altered relationship between the afferent input and perception/efferent response in FBD. Defining the nature of food-related ...
< 2 3 4 5 6 7 8 9 10 11 12 >