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Results 451 - 500 of 2770
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Gupta N - - 2012
N. Gupta, N. Dudding, J. Crossley, S.J. Payyappilly and J.H.F. Smith Outcome of SurePath™ cervical samples reported as borderline nuclear changes by cytological subtype and high-risk HPV status Background:  The average borderline rate in cervical cytology samples for English laboratories was 3.8% with the range being 2.0-6.8% at the time ...
Hünig Thomas - - 2012
The life-threatening cytokine-release syndrome suffered by six volunteers in a Phase I clinical trial following administration of the CD28 superagonist antibody TGN1412 (developed by TeGenero) in March 2006 was completely unpredicted by the preclinical studies. Here, Thomas Hünig, main founder of TeGenero, describes the recent investigations into what went wrong ...
Murase Seiichiro - - 2012
An MoO(3) film spin-coated from a solution prepared by an extremely facile and cost-effective synthetic method is introduced as an anode buffer layer of bulk-heterojunction polymer photovoltaic devices. The device efficiency using the MoO(3) anode buffer layer is comparable to that using a conventional PEDOT:PSS layer without annealing at an ...
Reedijk Jan - - 2012
The binding of transition metal compounds to nucleic acids is discussed in the perspectives of kinetics and their anticancer activity. Kinetics of ligand exchange is primarily determined by the intrinsic properties of the metal ions, and to a lesser degree by the ligands coordinated already to the metal ion. Metal ...
Kanda N - - 2012
BACKGROUND: Skin lesions with atopic dermatitis (AD) are associated with dysregulated expression of LL-37 and enhanced expression of IL-22, thymic stromal lymphopoietin (TSLP), IL-25, IL-31, and oncostatin M. Vitamin D3 enhances LL-37 production in keratinocytes. This study aimed to examine the serum levels of LL-37 and vitamin D3 and their ...
Brinkman Adam S - - 2012
Lipoblastoma is a rare benign neoplasm of embryonic white fatty tissue primarily found in the extremities of children <3 years old (Batanian et al., Cancer Genet Cytogenet 125(1):10-13, 2001; McVay MR et al., J Pediatr Surg 41(6):1067-1071, 2006; Kamal et al., J Pediatr Surg 46(7):E9-E12, 2011). Translocations affecting the 8q11-13 region ...
Rusch George M - - 2012
HFO-1234ze is being developed as a refrigerant, propellant, and foam-blowing agent because it has a very low global warming potential (less than 10), as contrasted to the hydrofluorocarbons with values of over 500. Several toxicology studies were conducted to develop a toxicology profile for this material. There was no lethality ...
Liu Jianqing - - 2012
A new anticalin against estradiol (E(2)), a kind of endocrine disruptor, was obtained in the present study to detect E(2) levels. A member of the lipocalin family from Pieris brassicae called bilin-binding protein (BBP) was employed for the preparation of a random library to specifically complex E(2). Sixteen amino acid ...
Alhamdani A - - 2012
BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) is one of the commonest bariatric procedures in the UK. This study reports our experience with this procedure over the last 10 years. METHODS: A prospectively maintained database of all the patients undergoing LAGB at our centre between March 2000 and August 2010 was analysed. ...
Okafor Maria-Theresa C - - 2012
Although over 1.5 million African immigrants live in the US, few studies have examined the relationship of language acculturation to health outcomes among African immigrant adults. The primary objective of this research was to investigate the relationship between English proficiency and current self-rated health among African immigrant adults. Using a cross-sectional ...
Lee Hyo-Jong - - 2012
OBJECTIVES AND DESIGN: Arbutin, which is found in the genus Arctostaphylos, is an anti-oxidant and a depigmenting agent. The present study was designed to validate the anti-inflammatory effect of arbutin. MATERIALS AND METHODS: The anti-inflammatory properties of arbutin were studied using a lipopolysaccharide (LPS)-stimulated murine BV2 microglial cells model. As ...
Perelaer Jolke - - 2012
A combination of photonic and microwave flash exposure is used to sinter inkjet printed silver nanoparticles. This approach leads to conductive features on polymer substrates in short times that are compatible with roll-to-roll production. The sequential process of sintering the as-printed features revealed a final conductivity of 40% of bulk ...
Trejo-Acevedo Antonio - - 2012
The aim of this study was to evaluate hexachlorocyclohexane (HCH) exposure in children living in nine hot spots in four Mexican states. We analyzed HCH (α, β, and γ-isomers) in blood using gas chromatography/mass spectrometry. HCH exposure level in 261 children was assessed and approximately 75 % of the children studied ...
Sieper Joachim - - 2012
First-line therapy for spondyloarthritis (SpA) has not yet altered in the wake of new classification criteria; NSAIDs and physical therapy are recommended. Anti-TNF agents can be used when NSAIDs fail, but their efficacy has potentially been limited in previous trials by inclusion criteria requiring the presence of established, active disease. ...
Balić Davor - - 2012
To investigate the degree of genetic variability of bovine leukemia virus (BLV) strains circulating in Croatia, 29 isolates from the six largest dairy farms were examined by PCR for a segment of the gp51 env gene, followed by DNA sequencing and phylogenetic analysis. The nucleotide sequences were compared with other ...
Rahir Gwendoline - - 2012
There is ample evidence that the presence of tumor-infiltrating T lymphocytes is associated with a favorable prognostic in patients. These observations suggest that a limiting step to immune resistance and immunotherapy could be the capacity of tumor-specific T cells to reach tumor bed. In this article, we review some factors ...
Martineau Charlotte - - 2012
We present in this paper the structure resolution of a fluorinated inorganic-organic compound-Zn(3)Al(2)F(12)·[HAmTAZ](6)-by SMARTER crystallography, i.e. by combining powder X-ray diffraction crystallography, NMR crystallography and chemical modelling of crystal (structure optimization and NMR parameter calculations). Such an approach is of particular interest for this class of fluorinated inorganic-organic compound materials ...
Theocharis Stamatios - - 2012
PURPOSE: Focal adhesion kinase (FAK) and Src are protein tyrosine kinases, localized in the focal adhesions, which, upon activation interacts each other, regulate several cellular signaling pathways implicated in malignant transformation and disease progression. The present study aimed to evaluate the clinical significance of FAK and Src protein expression in ...
Shan Changsheng - - 2012
A large quantity of highly conductive graphene was prepared by a novel CVD method with nickel powder as a template and PMMA as carbon source. With Pt as a model, PtNP-modified graphene showed much better electrocatalytic ability for O(2) and methanol than PtNP-reduced graphene oxide (RGO) and commercial Pt/C, showing ...
Manna Prasenjit - - 2012
Abstract In this review article, we describe the most recent development of the beneficial effect of arjunolic acid (AA) in reducing type 1 diabetic pathophysiology. Diabetic mellitus is a serious and growing health problem worldwide. Increasing evidence suggest that oxidative stress plays a pivotal role in the pathogenesis of diabetes ...
Tabuchi Masahiro - - 2012
18β-Glycyrrhetinic acid (GA) is a major metabolite of glycyrrhizin (GL), which is one of the components of glycyrrhiza root, a constituent herb of the traditional Japanese medicine yokukansan. It is well known that most GL is metabolized to GA in the intestine by bacteria. A previous in vitro study using ...
Austin Julia L - - 2012
Adherence to behavioral weight management programs is often limited, especially among ethnic minority populations. The current study examined whether attitudinal familism, or attention to the needs of family above those of the self, predicted poorer adherence to a behavioral weight management program in Mexican-American women. One-hundred overweight or obese Mexican-American ...
Lee Seunghyup - - 2012
The resistive switching (RS) characteristics of a tungsten oxide (WO(x) )-Au core-shell nanowire device array is demonstrated for the first time. In addition to the stable bipolar RS characteristics, the nanowire structure of our RS devices provides superhydrophobic properties. The superhydrophobic RS nanowires repelled water that was poured over, such ...
Schnüriger Beat - - 2012
BACKGROUND: The predictive factors to regain a heartbeat following emergency department resuscitative thoracotomy (EDT) for trauma are poorly understood. The objective of the present study was to prospectively assess the electrolyte profile, coagulation parameters, and acid-base status from intracardiac blood samples in trauma patients subjected to open cardiopulmonary resuscitation (CPR) ...
Wang Lisu - - 2012
Chronic arsenic exposure has been linked to an increased risk of vascular diseases. To clarify the molecular mechanisms through which arsenic causes injuries to blood vessels, we analyzed the effects of arsenic trioxide on the cytotoxicity, intracellular reactive oxygen species (ROS), the expression of related genes, and signaling pathways involved ...
Raap Ulrike - - 2012
The oral mucosa is constantly exposed to a large number of potentially irritating and sensitizing dental materials. Dental materials used for fillings and fixed or removable replacements must have a good biocompatibility. Metals including palladium are used in alloys for the production of the core of crowns, onto which porcelain ...
Tonner Ralf - - 2012
In an effort to understand the chemical factors that stabilize dianions, experimental and theoretical studies on the stability of the tartrate dianion were performed. Quantum chemical calculations at the coupled cluster level reveal only a metastable state with a possible decomposition pathway (O2C-CH(OH)-CH(OH)-CO2)2- -> (O2C-CH(OH)-CH(OH))•- + CO2 + e- explaining ...
Yue Hairong - - 2012
Ethylene glycol (EG) is an important organic compound and chemical intermediate used in a large number of industrial processes (e.g. energy, plastics, automobiles, and chemicals). Indeed, owing to its unique properties and versatile commercial applications, a variety of chemical systems (e.g., catalytic and non-catalytic) have been explored for the synthesis ...
Peltzer Karl - - 2012
The aim of this study was to describe sexual risk behavior among 239 couples during pregnancy and to examine the relationship of sexual risk behavior with HIV serostatus and intimate partner violence. One-third (31.8 %) of pregnant women and 20.9 % of male partners were HIV positive. HIV risk factors included lack ...
Mona Mohammed H - - 2012
Context:Holothuria polii (H. polii)Linnaeus (Holothuriidae),Actinopyga mauritiana (A. mauritiana) Quoy & Gaimard (Holothuriidae) andBohadschia vitiensis(B. vitiensis) Semper (Holothuriidae) are sea cucumbers inhabiting the coasts of Egypt. Their tegument and the cuvierian gland contained a substance called holothurin that was used in traditional medicine. These three species are abundant in the Egyptian ...
Jones Judith K - - 2012
PURPOSE: Emerging interests in pharmacoepidemiology make it important to define the profession's core content. The International Society for Pharmacoepidemiology (ISPE)'s Education Committee sought to develop a consensus on its core disciplines. This report recapitulates their efforts and conclusions. METHODS: The survey for skill inventories conducted characterized the field of pharmacoepidemiology ...
Zheng Jian - - 2012
Context: Liquid-liquid extraction (LLE) shows high efficiency in the plasma sample preparation. However, this extraction method is not optimal for the biological samples containing complex organic interferences, such as liver and brain tissues. Some plant secondary metabolites can be converted between water-insoluble and water-soluble forms by pH adjustment. Objective: A ...
Zhang Min - - 2012
To increase thermotolerance and ethanol tolerance in Saccharomyces cerevisiae strain YZ1, the strategies of high-energy pulse electron beam (HEPE) and three rounds of protoplast fusion were explored. The YF31 strain had the characteristics of resistant to high-temperature, high-ethanol tolerance, rapid growth and high yield. The YF31 could grow on plate ...
Gerhard Pascal - - 2012
PURPOSE: The primary purpose of our study was to analyse the long-term outcome of patients treated for anterior cruciate ligament (ACL) tears by anatomical single-bundle ACL reconstruction with patellar tendon autograft. The secondary purpose was to identify predictive factors for good outcome and occurrence of osteoarthritis. METHODS: Sixty-three patients (m:f = 54:9; ...
Issack Bilkiss B - - 2012
Essential collective dynamics is a promising and robust approach for analysing the slow motions of macromolecules from short molecular dynamics trajectories. In the current work, an extension of the method to treat a collection of interacting protein molecules is presented. The extension is applied to investigate the effects of dimerisation ...
Del Turco Serena - - 2012
Advanced glycation endproducts (AGEs) are a group of modified molecular species formed by nonenzymatic reactions between the aldehydic group of reducing sugars with proteins, lipids, or nucleic acids. Formation and accumulation of AGEs are related to the aging process and are accelerated in diabetes. AGEs are generated in hyperglycemia, but ...
Kalkan Yildiray - - 2012
The protective effects of Panax ginseng (PG) on gentamicin sulphate (GS) induced acute nephrotoxicity were investigated in rats. A total of 32 adult Sprague-Dawley rats were randomly divided into 4 equal groups and treated by intraperitoneous route for 10 days with: 0.5 mL of isotonic saline (group C), GS 100 mg/kg/day (group GS), ...
López-Jornet Pia - - 2012
Gerodontology 2012; doi: 10.1111/j.1741-2358.2012.00671.x Short-term side effects of 0.2% alcohol-free chlorhexidine mouthrinse in geriatric patients: a randomized, double-blind, placebo-controlled study Objective:  To determine the effects of a 0.2% alcohol-free chlorhexidine mouthwash applied twice a day during 30 days in patients over 65 years of age. Materials and methods:  A randomized, double-blind, placebo-controlled ...
Toksen Erol - - 2012
Sagum posteli Delamare-Deboutteville & Nunes-Ruivo, 1954 (Copepoda: Lernanthropidae) is reported from the white grouper Epinephelus aeneus Geoffroy Saint-Hilaire caught off the Turkish Mediterranean coast. This documents the first discovery of this species in the Mediterranean and is only the second record. The species is redescribed from adult females and the ...
Mason Kevin - - 2012
Strapping two salicylaldoxime units together with aliphatic α,Ω-aminomethyl links in the 3-position gives ligands which allow the assembly of the polynuclear complexes [Fe(7)O(2)(OH)(6)(H(2)L1)(3)(py)(6)](BF(4))(5)·6H(2)O·14MeOH (·6H(2)O·14MeOH), [Fe(6)O(OH)(7)(H(2)L2)(3)](BF(4))(3)·4H(2)O·9MeOH (·4H(2)O·9MeOH) and [Mn(6)O(2)(OH)(2)(H(2)L1)(3)(py)(4)(MeCN)(2)](BF(4))(5)(NO(3))·3MeCN·H(2)O·5py (·3MeCN·H(2)O·5py). In each case the metallic skeleton of the cluster is based on a trigonal prism in which two [M(III)(3)O] triangles are ...
Nadiki Hadi Hassani - - 2012
A new modified carbon paste electrode based on multi-walled carbon nanotubes and a synthesized Schiff base of N,N'-bis(2-hydroxybenzylidene)-2,2'(aminophenylthio) ethane, acting as a chelating agent for Ag(i) ions, is described. The electroanalytical procedure for the determination of Ag(i) was comprised of two steps: the chemical accumulation of the analyte under open-circuit ...
Bethell Christina - - 2012
School success predicts many pathways for health and well-being across the life span. Factors promoting or potentially impeding school success are critical to understand for all children and for children with special health care needs (CSHCN), whose life course trajectories are already impacted by their chronic health problems. The 2007 ...
Zhang Liwu - - 2012
One putative quantitative trait locus (QTL) for seeds per silique (SS), cqSS.A8, was identified using a double haploid (DH) population in Brassica napus, and near-isogenic lines (NILs; BC(3)F(1)) for cqSS.A8 were developed. However, the flanking markers from cqSS.A8 showed no significant difference using single-marker analysis, even though the frequency distribution ...
Nicholson David - - 2012
OBJECTIVE AND DESIGN: A mathematical analysis of leukocytes accumulating in experimental autoimmune uveitis (EAU), using ordinary differential equations (ODEs) and incorporating a barrier to cell traffic. MATERIALS AND SUBJECTS: Data from an analysis of the kinetics of cell accumulation within the eye during EAU. METHODS: We applied a well-established mathematical ...
Lai Yu - - 2012
Despite substantial progress that has been made in understanding many aspects regarding biology and pathogenesis of human immunodeficiency virus type 1 (HIV-1), there is currently no vaccine or curative treatment available. HIV-1 continues to be a major global health problem. In this regard, new strategies are required for promoting a ...
Hardman L M - - 2012
A phylogenetic analysis was carried out on rDNA of 45 species of anoplocephaline cestodes from marsupial hosts. The exclusively Australasian genera Progamotaenia Nybelin, 1917, Triplotaenia Boas, 1902, Paramoniezia Maplestone & Southwell, 1923 and Phascolotaenia Beveridge, 1976 formed a monophyletic clade, and the previously suggested relationship between the Australasian species of ...
Eyley Samuel - - 2012
Ferrocene-decorated cellulose nanowhiskers were prepared by the grafting of ethynylferrocene onto azide functionalized cotton-derived cellulose nanowhiskers using azide-alkyne cycloaddition. Successful surface modification and retention of the crystalline morphology of the nanocrystals was confirmed by elemental analysis, inductively coupled plasma-atomic emission spectroscopy, X-ray photoelectron spectroscopy, and X-ray diffraction. The coverage with ...
Wang Yan - - 2012
Because of their plasticity and availability, bone-marrow-derived mesenchymal stem cells (MSC) are a potential cell source for treating ischemic heart disease. Schwann cells (SC) play a critical role in neural remodeling and angiogenesis because of their secretion of cytokines such as vascular endothelial growth factor (VEGF). Cell microencapsulation, surrounding cells ...
Georgiadou Michaella - - 2012
The functionally versatile type IV pili (Tfp) are one of the most widespread virulence factors in bacteria. However, despite generating much research interest for decades, the molecular mechanisms underpinning the various aspects of Tfp biology remain poorly understood, mainly because of the complexity of the system. In the human pathogen ...
Zeng Huan - - 2012
The preparation of magnetic molecularly imprinted polymers (MMIPs) which can be used for the separation and purification of rutin from Chinese medicinal plants has been proposed. By applying the improved co-precipitation method, magnetic Fe(3)O(4) particles were easily prepared, followed by the modification of TEOS and functionalization with -CH[double bond, length ...
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