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Results 251 - 300 of 3791
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Reymer Anna - - 2012
Opposite enantiomers of [Ru(phenanthroline)(3)](2+) affect the persistence length of DNA differently, a long speculated effect of helix kinking. Our molecular dynamics simulations confirm a substantial change of duplex secondary structure produced by wedge-intercalation of one but not the other enantiomer. This effect is exploited by several classes of DNA operative ...
Wang Cui - - 2012
Thumb polydactyly is a common congenital abnormality of the hand. Surgical treatment includes reduction and reconstruction. A new type of thumb polydactyly and the achieved treatment are reported. A 4-year-old boy with thumb polydactyly is reported. The duplicated two thumbs had one complete metacarpal and a separated triphalangeal phalanx. The ...
Zedda Marco - - 2012
This review focuses on the possibilities and limits of nontarget screening of emerging contaminants, with emphasis on recent applications and developments in data evaluation and compound identification by liquid chromatography-high-resolution mass spectrometry (HRMS). The general workflow includes determination of the elemental composition from accurate mass, a further search for the ...
Kanamori Toshiyuki - - 2012
Filtration, namely, convective mass transport through a hemodialysis membrane, has recently been utilized in maintenance hemodialysis to enhance the removal of high-molecular-weight uremic toxins. However, it has been practically impossible to estimate the clearance of solutes from hemodialyzers operated at predetermined net filtration rates, even if the mass-transfer parameters of ...
Delgado Salvadora - - 2012
BACKGROUND: Sleeve gastrectomy is gaining relevance in the surgical armamentarium against obesity. The transumbilical single port has proved to be an attractive and safe alternative for a variety of minimally invasive abdominal surgeries. The purpose of this study is to evaluate the initial results of a group of patients operated ...
Andrade Evelyn R - - 2012
SummaryThe objective of this study was to evaluate the effects of adding ascorbic acid to the media for in vitro culture of cattle ovarian fragments and to determine their effects on growth activation and viability of early-stage follicles. The ovarian cortex was divided into small fragments; one fragment was immediately ...
Yamamoto Naomichi - - 2012
Fungi are ubiquitous in outdoor air, and their concentration, aerodynamic diameters and taxonomic composition have potentially important implications for human health. Although exposure to fungal allergens is considered a strong risk factor for asthma prevalence and severity, limitations in tracking fungal diversity in air have thus far prevented a clear ...
Oruçoğlu Faik - - 2012
To determine the incidence of recurrent epithelial loosening (REL) following laser in situ keratomileusis (LASIK) and evaluate the efficacy of anterior stromal micropuncture (ASP) and the application of bandage contact lenses (BCLs) in the management of REL after LASIK. A retrospective study including all individuals who underwent LASIK with a ...
Pasteau Magali - - 2012
Song discrimination and recognition in songbird species have usually been studied by measuring responses to song playbacks. In female canaries, Serinus canaria, copulation solicitation displays (CSDs) are used as an index of female preferences, which are related to song recognition. Despite the fact that many studies underline the role of ...
Fang Fang - - 2012
Receiving a diagnosis of cancer is a traumatic experience that may trigger immediate adverse health consequences beyond the effects of the disease or treatment. Using Poisson and negative binomial regression models, we conducted a historical cohort study involving 6,073,240 Swedes to examine the associations between a cancer diagnosis and the ...
Weber Roland W - - 2012
BACKGROUND: We sought to prospectively determine foetal echocardiographic factors associated with neonatal interventions in borderline hypoplastic left ventricles. METHODS: Foetuses were included who had a left ventricle that was 2-4 standard deviations below normal for length or diameter and had forward flow across the mitral and aortic valves. Factors associated ...
Wasala Nalinda B - - 2012
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine produced by many mammalian tissues. It is also found in ticks and may function to aid the tick in regulating host responses to tick feeding. Our hypothesis is that MIF functions in tick blood meal acquisition and pathogen transmission. This study ...
Canivet Catarina - - 2012
OBJECTIVES: The aim of this study was to investigate whether job strain, psychological demands, and decision latitude are independent determinants of disability pension rates over a 12-year follow-up period. METHODS: We studied 3,181 men and 3,359 women, all middle-aged and working at least 30 h per week, recruited from the general ...
Safwani Wan Kamarul Zaman Wan - - 2012
Adipose tissue is a source of multipotent stem cells and it has the ability to differentiate into several types of cell lineages such as neuron cells, osteogenic and adipogenic cells. Most studies on human adipose-derived stem cells (ASCs) have been carried out at the early passages. For clinical usage, ASCs ...
Peipins Lucy A - - 2012
Access to screening mammography may be limited by the availability of facilities and machines, and nationwide mammography capacity has been declining. We assessed nationwide capacity at state and county levels from 2003 to 2009, the most recent year for which complete data were available. Using mammography facility certification and inspection ...
Small David M - - 2012
Acute kidney injury (AKI) in critically ill patients is closely associated with increased morbidity and mortality, yet there remains continued reliance on increased serum creatinine and blood urea nitrogen to diagnose AKI. These biomarkers increase only after significant renal structural damage has occurred. Recent research efforts have focused on discovery ...
Cherniack E Paul - - 2012
Today, tens of millions of elderly individuals worldwide suffer from dementia. While the pathogenesis of dementia is complex and incompletely understood, it may be, at least to a certain extent, the consequence of systemic vascular pathology. The metabolic syndrome and its individual components induce a proinflammatory state that damages blood ...
Chu Xiao-Man - - 2012
PURPOSE: The aim of this study was to investigate the genetic polymorphisms of UGT1A3, UGT1A6, and UGT2B7 in Chinese epilepsy patients and their potential influence on the pharmacokinetics of valproic acid (VPA). METHODS: The genetic architectures of UGT1A3, UGT1A6, and UGT2B7 in 242 epilepsy patients were detected by DNA sequencing ...
Hardcastle Sarah - - 2012
Little research exists on the impact of behavior change interventions in disadvantaged communities. We conducted a prospective study to explore the effectiveness of motivational interviewing on physical activity change within a deprived community and the social- psychological and motivational predictors of change in physical activity including stage of change, self-efficacy, ...
Lankelma Jan - - 2012
This communication describes a new design for a paper-based electrochemical system for flow-injection analysis. Capillary wicking facilitates a gravity-driven flow of buffer solution continuously through paper and nitrocellulose, from a buffer reservoir at one end of the device, to a sink, at the other. A difference in height between the ...
Dånmark S - - 2012
In vitro, degradable aliphatic polyesters are widely used as cell carriers for bone tissue engineering, despite their lack of biological cues. Their biological active surface is rather determined by an adsorbed layer of proteins from the surrounding media. Initial cell fate, including adhesion and proliferation, which are key properties for ...
Sasisekaran Jayanthi - - 2012
The aim of the present study was to investigate the effects of cognitive-linguistic variables and language experience on behavioral and kinematic measures of nonword learning in young adults. Group 1 consisted of thirteen participants who spoke American English as the first and only language. Group 2 consisted of seven participants ...
Ross Robert D - - 2012
Accurate grading of the presence and severity of heart failure (HF) signs and symptoms in infants and children remains challenging. It has been 25 years since the Ross classification was first used for this purpose. Since then, several modifications of the system have been used and others proposed. New evidence has ...
Patel Vishal - - 2012
Internal herniation through the foramen of Winslow is a rare cause of abdominal hernia. We describe a case in which caecal herniation through the foramen of Winslow was diagnosed using various imaging modalities, including computed tomography and managed operatively through hernia identification, caecal reduction and foramen closure. The literature is ...
Aktas Erdem - - 2012
BACKGROUND: To investigate the efficacy of a topically applied hemostatic agent used to reduce blood loss in patients undergoing simultaneous bilateral total knee arthroplasty (TKA). METHODS: Thirty-two patients (5 male, 27 female) mean age 65 ± 9.3 (46-80) undergoing single-stage bilateral TKA were enrolled in the study and divided in two groups. ...
Biswas Manosh Kumar - - 2012
Pummelo (Citrus grandis) is one of the most important species found in the genus Citrus and one of the ancestors of sweet oranges. We used flower buds at different developmental stages to construct the first cDNA library for this species. A total of 3,758 EST sequences were generated from the ...
Kuntworbe Noble - - 2012
Cryptolepine hydrochloride-loaded gelatine nanoparticles were developed and characterised as a means of exploring formulation techniques to improve the pharmaceutic profile of the compound. Cryptolepine hydrochloride-loaded gelatine-type (A) nanoparticles were developed base on the double desolvation approach. After optimisation of formulation parameters including temperature, stirring rate, incubation time polymer and cross-linker ...
Song Chan-Hee - - 2012
Zinc (Zn) and copper (Cu) are essential micronutrients involved in numerous metabolic reactions. They are also antagonists of the N-methyl-D: -aspartate glutamate (NMDA) receptor in the central nervous system, which mediates mood, cognition, pain perception, and sleep. However, there have been few studies on the effects of Zn and Cu ...
Gumus Burçak - - 2012
PURPOSE: To present our clinical experience and to suggest different strategies in the management of dysfunctioning plastic biliary stents in patients with malignant biliary obstruction. MATERIALS AND METHODS: Twenty females and 23 males with a mean age of 64.8 years (range, 30-89 years) with malignant obstructive jaundice were referred to ...
Palter Vanessa N - - 2012
BACKGROUND: Laparoscopic colorectal surgery is considered an advanced minimally invasive procedure with a long, variable learning curve. Developing an evaluation tool is essential to ensure that individuals reach a certain level of competence prior to performing this procedure independently. To achieve standardization and wide implementation, an assessment tool must be ...
Köşüş Nermin - - 2012
PURPOSE: This study aimed to examine two-dimensional ultrasound (2D US) volumetric measurements of 1st trimester structures and their relationship with β-hCG, progesterone, and fetal heart rate (FHR) in 6-10 weeks healthy pregnant women. METHODS: Using conventional 2D transvaginal ultrasound imaging, the crown rump length (CRL), yolk sac (YS) and gestational sac ...
Hu Yanfeng - - 2012
The plant hormone auxin plays a central role in the regulation of plant growth and development, as well as in responses to environmental stimuli. Narciclasine (NCS, an Amaryllidaceae alkaloid) isolated from Narcissus tazetta bulbs has a broad range of inhibitory effects on plants. In this study, the role of NCS ...
Goto Kenichi - - 2012
This study was designed to determine whether a high-salt diet would alter endothelial function and, if so, the relative contributions of endothelium-derived hyperpolarizing factor (EDHF) and nitric oxide (NO) to any changes in vasomotor responses. Male Dahl salt-sensitive (DS) rats were given either a high-salt diet (8% NaCl, DS-H) or ...
Wittmann Marion E - - 2012
Anoxia can restrict species establishment in aquatic systems and the artificial promotion of these conditions can provide an effective control strategy for invasive molluscs. Low abundances (2-20 m(-2)) of the nonnative bivalve, Asian clam (Corbicula fluminea), were first recorded in Lake Tahoe, CA-NV in 2002 and by 2010 nuisance-level population densities ...
Ohtsuka Keiichi - - 2012
When a biotinylated FRET probe based on a peptide-thrombin binding aptamer conjugate was introduced together with streptavidin and biotinylated nuclear export signal peptide into HeLa cells, the resulting ternary complex enabled visualization of K(+) concentration changes in the cell.
Eide Melody J - - 2012
Health maintenance organization (HMO) administrative databases have been used as sampling frames for ascertaining nonmelanoma skin cancer (NMSC). However, because of the lack of tumor registry information on these cancers, these ascertainment methods have not been previously validated. NMSC cases arising from patients served by a staff model medical group ...
Hoe M - - 2012
BACKGROUND: Social cognition has been identified as a significant construct for schizophrenia research with relevance to diagnosis, assessment, treatment and functional outcome. However, social cognition has not been clearly understood in terms of its relationships with neurocognition and functional outcomes. The present study sought to examine the empirical independence of ...
Kaialy Waseem - - 2012
PURPOSE: To co-crystallise mannitol and lactose with a view to obtaining crystals with more favourable morphological features than either lactose or mannitol alone, suitable for use as carriers in formulations for dry powder inhalers (DPIs) using simultaneous engineering of lactose-mannitol mixtures. METHODS: Mannitol and lactose individually and the two sugars ...
Ho Fu Han - - 2012
We have successfully demonstrated a novel sensing technique for monitoring the variation of solution concentrations and measuring the effective dielectric constant in a medium by means of an ultra-small and label-free nanosensor, the mechanism of which is based on the localized surface plasmon resonance (LSPR) of gold nanorods. The nanorods ...
Brito A B - - 2012
SummaryThere is no tradition in studies reporting the effect of exposure to cryoprotectants or simply hypoxia and hypothermia on gene expression in the ovarian tissue and there has been only one study on reference or target genes quantification, and comparisons of normoxic with hypoxic, hypothermic and toxic conditions. Our aim ...
Kawabe Joji - - 2012
F-18 FDG PET/CT has been widely used to diagnose primary tumors and lymph node metastases and to evaluate the response of head and neck squamous cell carcinoma (HNSCC) to therapy. The advantage of using PET/CT is that this combination allows metabolic information to be precisely overlapped with anatomical information, thereby ...
Mao H - - 2012
Inflammatory bowel disease is well recognized for a strong genetic involvement in its pathogenesis. Homozygous mutations in interleukin-10 receptor 1 (IL-10R1) identified by linkage analysis were shown to be involved in this disorder. However, the underlying molecular mechanism and the causal nature of the mutations in the disease process remain ...
Vivier Emmanuel - - 2012
PURPOSE: Ultrasonography allows the direct observation of the diaphragm. Its thickness variation measured in the zone of apposition has been previously used to diagnose diaphragm paralysis. We assessed the feasibility and accuracy of this method to assess diaphragmatic function and its contribution to respiratory workload in critically ill patients under ...
Lucas-Carrasco Ramona - - 2012
ABSTRACTBackground: Depressive symptoms are prevalent among persons with dementia (PWD). Our aim was to assess the psychometric properties of the Spanish version of the Geriatric Depression Scale (GDS-15 and GDS-5) in PWD.Methods: In this cross-sectional study, five healthcare centers providing care for PWD from two cities in Spain participated. Ninety-six ...
Kang Jeonghyun - - 2012
PURPOSE: To compare the short-term perioperative results and long-term oncologic outcomes between patients who underwent neoadjuvant chemoradiotherapy (NCRT) and patients who underwent postoperative adjuvant chemoradiotherapy (ACRT) for stage III rectal cancer. METHODS: From January 1997 to December 2008, a total of 47 patients who were diagnosed as clinical stage III ...
Cui Qinghua - - 2012
Due to their good photostability, high quantum yield and low toxicity, fluorescent silver nanoclusters (Ag NCs) have received much attention as novel fluorophores for sensing applications. In this work, we investigate the upconversion emission of Ag NCs templated by single- and double-stranded DNAs. DNA-templated Ag NCs exhibit upconversion emission at wavelengths identical to ...
Prandl Kelly J - - 2012
Despite Australia's high standard of health care provision, Australian Aboriginal women continue to experience poor pregnancy outcomes in terms of maternal and foetal morbidity and mortality. In an attempt to improve these outcomes, health care providers have developed targeted antenatal programmes that aim to address identified health behaviours that are ...
Zuo Qinhua - - 2012
In this study, calcium-alginate microgels coated with a polyelectrolyte multilayer (PEM) were fabricated as a controlled-release system. This system was constructed via an electrostatic droplet generation technique followed by a layer-by-layer (LbL) self-assembly technique. The electrostatic droplet generation technique was reported as an easy method of preparing microgels, due to ...
Jena Srikanta - - 2012
The present investigation was aimed to elucidate the effect of curcumin on lipid peroxidation (LPx) and superoxide dismutase (SOD) in L: -thyroxine (T(4))-induced oxidative stress in cerebral cortex and cerebellum of rat brain. Elevated level of LPx in cerebral cortex declined to control level on supplementation of curcumin to T(4)-treated ...
Koehler Nicole - - 2012
Background: Patients generally have positive attitudes regarding being examined by a supervised medical student as part of their medical care. However, it is difficult to obtain model patients for students to examine purely for teaching purposes (i.e. in the absence of medical treatment). Aims: This study explored the effects of ...
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