Search Results
Results 201 - 250 of 2952
< 1 2 3 4 5 6 7 8 9 10 >
Liu Qiang - - 2012
No pressure: The oxidation of aromatic CH bonds at room temperature was realized through a copper-catalyzed "oxygenase-type" oxidation of arenes and heteroarenes in the presence of air. The reaction involves an oxygen-atom transfer from O(2) in the air onto the substrates.
Agren Göran I - - 2012
• All plant species require at least 16 elements for their growth and survival but the relative requirements and the variability at different organizational scales is not well understood. • We use a fertiliser experiment with six willow (Salix spp.) genotypes to evaluate a methodology based on Euclidian distances for ...
Dohnke B - - 2012
Hospital treatments are assumed to be a 'teachable moment'. This phenomenon, however, is only poorly conceptualised and untested. A stage-theoretical perspective implies that a cueing event such as hospital treatments is a teachable moment if a stage progression, change of cognitions, or both occur. This concept is examined in a ...
Zhou Dezhong - - 2012
A novel multifunctional oligomer is synthesized and incorporated to enhance the gene delivery efficiency of PLL via non-electrostatic assembly and covalent grafting strategies. The improvement of the gene delivery efficiency is dependent on the gene carrying complex properties, and the properties are dependent on the oligomer incorporation strategy.
Yuan Longyan - - 2012
Energy storage on paper: Paper-based, all-solid-state, and flexible supercapacitors were fabricated, which can be charged by a piezoelectric generator or solar cells and then discharged to power a strain sensor or a blue light-emitting diode, demonstrating its efficient energy management in self-powered nanosystems.
Ueda Takunori - - 2012
A synthetic oxygen (O(2)) and carbon monoxide (CO) receptor (hemoCD) composed of 5,10,15,20-tetrakis(4-sulfonatophenyl)porphinatoiron(ii) and a per-O-methylated β-cyclodextrin dimer with a pyridine linker (Py3CD) was functionalised with poly(ethylene glycol) (PEG) to elongate the circulation time of the receptor in the bloodstream. α-PEG monocarboxylic acid (HOOC(CH(2))(3)(CO)O-PEG(mw)-OCH(3); mw = 750 or 5k) or ...
Bel Hadj Ali Insaf - - 2012
Background: Otosclerosis is a common form of hearing impairment among Western-Eurasian adults. The cause of otosclerosis remains unknown. Autoimmune reaction against the otic capsule has been suggested as a possible aetiologic factor in otosclerosis. Aim: The present study is the first report to evaluate the relationship between class I major ...
Wang Xiangfu - - 2012
Novel hexagonal Na(1.23)Ca(0.12)Y(1.28)Er(0.24)F(6) nanodisks, microtubes, and nanorods were synthesized hydrothermally for the first time. Time-dependent morphology evolution showed that the resulting nanodisks, microtubes, and nanorods were synthesized by a dissolution-reconstruction formation mechanism. With the help of a 980 nm semiconductor laser, tunable homochromatic luminescence was observed by exciting single hexagonal ...
Karam Marie Celeste - - 2012
Protein fortification and solubilisation into the milk base are important parameters enhancing yogurt texture. In this study, the milk base prepared from reconstituted skim milk powder was fortified with 2% of 'aged' (1 year old) or 'fresh' micellar casein (MC) powder. Micellar casein powders were left to rehydrate at 20°C ...
Goodsaid Federico - - 2012
Biomarker data are essential in the discovery and development of new drugs. However, pathways needed to make sure that biomarker data are accepted by regulatory agencies may be considered an unnecessary burden on the critical path for drug development. There is the need to consider early in discovery and development ...
Less Robert J - - 2012
The reactions of Na[C(5)(CN)(5)] (Na[]) with group 11 phosphine complexes [(P)(n)MCl] (M = Cu, Ag, Au, P = Ph(3)P; M = Cu, P = dppe (Ph(2)PCH(2)CH(2)PPh(2))] give a range of compounds containing the pentacyanocyclopentadienide ligand, [C(5)(CN)(5)](-) (). The new complexes [(Ph(3)P)(2)M{}](2) [M = Cu (); M = Ag ()], [(Ph(3)P)(3)Ag{}] ...
Zhang Jing-Jing - - 2012
Gold cures: The depicted gold(III) complex self-assembles into supramolecular polymers which form nanofibrillar networks that display sustained cytotoxicity and can also act as carriers for other cytotoxic agents.
Bottero D - - 2012
Aims:  Characterize Bordetella pertussis vaccine strains in comparison with current circulating bacteria. Methods and Results:  Genomic and proteomic analysis of Bp137 was performed in comparison with other vaccine strains used in Latin America (Bp509, and Bp10536) and with the clinical Argentinean isolate Bp106. Tohama I strain was used as reference ...
Zhu Saijie - - 2012
Stimulus-sensitive micelles are attractive anticancer drug delivery systems. Herein we reported a novel strategy to engineer acid-sensitive micelles using a amphiphilic material synthesized by directly conjugating the hydrophilic polyethylene glycol (PEG) with a hydrophobic stearic acid derivative (C18) using an acid-sensitive hydrazone bond (PHC). An acid-insensitive PEG-amide-C18 (PAC) compound was ...
Sehga Virendra N - - 2012
  A favorable response to narrow-band ultraviolet B light treatment, a novel option, is illustrated in familial reactive perforating collagenosis, and its use is recommended. Its probable mode of action is outlined.
Klein Andrea - - 2012
Ryanodine receptor 1 (RYR1) mutations are a common cause of congenital myopathies associated with both dominant and recessive inheritance. Histopathological findings frequently feature central cores or multi-minicores, more rarely, type 1 predominance/uniformity, fiber-type disproportion, increased internal nucleation, and fatty and connective tissue. We describe 71 families, 35 associated with dominant ...
Nyunt M M - - 2012
The centuries-old antimalarial drug, quinine, continues to play a critical role in the treatment of severe falciparum malaria and uncomplicated malaria in pregnant women. It shares cytochrome P450 (CYP)-mediated metabolic pathways with several commonly used antiretroviral drugs, raising the potential for clinically important drug-drug interactions. A phase I pharmacokinetic study ...
Kavli M - - 2012
BACKGROUND: The mortality of patients suffering from acute decompensated liver disease treated in the intensive care unit (ICU) varies between 50% and 100%. Previously published data suggest that liver-specific score systems are less accurate compared with the ICU-specific scoring systems acute physiology and chronic health evaluation II (APACHE II) and ...
Hart John S - - 2012
Tripodal pyrrole imine and amide ligands provide platforms for combined primary and secondary coordination sphere interactions in square planar Pd and Cu, and octahedral Ti complexes.
Weissmann-Brenner Alina - - 2012
Objective. To compare maternal and neonatal outcomes of term large-for-gestational age (LGA) pregnancies and adequate-for-gestational age (AGA) pregnancies. Design. Retrospective analysis. Setting. Large university research medical center. Population. All term singleton LGA (birthweight ≥90(th) percentile) and AGA pregnancies (birthweight 10.1-89.9(th) percentile) delivering between 2004 and 2008. Methods. Data collected included ...
Robinson Pc - - 2012
Objectives:  Gout is a growing worldwide health problem especially in affluent countries such as Australia. Gout and hyperuricemia are associated with the metabolic syndrome, diabetes mellitus, obesity and hypertension. Importantly Australia has a growing prevalence of these important health problems. The aim of the study was to systematically review published ...
Song Min Sup - - 2012
The importance of the physiological function of phosphatase and tensin homologue (PTEN) is illustrated by its frequent disruption in cancer. By suppressing the phosphoinositide 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) pathway through its lipid phosphatase activity, PTEN governs a plethora of cellular processes including survival, proliferation, energy metabolism and cellular ...
Hirakawa Kazutaka - - 2012
An electron donor-connecting water-soluble porphyrin, meso-(1-pyrenyl)-tris(N-methyl-p-pyridinio)porphyrin, did not demonstrate singlet oxygen generating activity under photo-irradiation. The interaction with DNA successfully recovered the photosensitized singlet oxygen generation by this porphyrin.
Glimvall P - - 2012
Glimvall P, Wickström C, Jansson H. Elevated levels of salivary lactoferrin, a marker for chronic periodontitis? J Periodont Res 2012: doi: 10.1111/j.1600-0765.2012.01479.x. © 2012 John Wiley & Sons A/S Background and Objective:  Whole saliva is a complex mixture of fluids essential for the well-being of the oral hard and soft ...
Poon Peter Yam-Kau - - 2012
SUMMARY AT A GLANCE: While this is a single centre study, the size of the study population is not insignificant. The hypothesis is novel and provides room for another alternative biomarker for measuring outcomes in peritoneal dialysis, where current markers are less than satisfactory. ABSTRACT: Background Tumor necrosis factor-related apoptosis-inducing ...
Cho Youngjin - - 2012
Antifouling surfaces are critical for the good performance of functional materials in various applications including water filtration, medical implants, and biosensors. In this study, we synthesized amphiphilic triblock terpolymers (tri-BCPs, coded as KB) and fabricated amphiphilic nanofibers by electrospinning of solutions prepared by mixing the KB with poly(lactic acid) (PLA) ...
Poirier N - - 2012
Tolerance induction to alloantigens remains a major challenge in transplant immunology. Progress in the last decade of our understanding of T-cell activation has led to the development of new immunotherapeutic strategies to replace conventional immunosuppression which inhibits the immune system in a nonspecific way. In particular, positive and negative costimulatory ...
Feng Shengfei - - 2012
A polarization-independent optical sensor is created by fabricating a concentric gold ring grating with a period of 900 nm on the end facet of an optical fiber. The sensing function of this miniaturized device is realized by sending white light as a probe to the gold rings and collecting the ...
Edison E S - - 2012
Hemoglobinopathies are highly prevalent in Indian population. DNA analysis to detect causative mutations is required for identifying rare hemoglobin variants or when hematological results are discordant with the clinical phenotype. In this report, we describe a novel hemoglobin variant caused by a mutation in beta-globin gene, Codon 7 GAG→CAG (Glu→Gln) ...
Munro Natasha H - - 2012
Biomimetic materials which display the complexity of biominerals like nacre are synthetically difficult to prepare. The formation of chitin/calcium carbonate composites, where CaCO(3) is present as aragonite, was achieved via reacetylation of preformed chitosan scaffolds followed by the combination of presoaking of chitin templates with mineral solutions in the presence ...
Macher S - - 2012
Background and Objectives  Multicomponent collection (MCC) enables production and processing of various blood components during one apheresis session. In this prospective crossover study, the effects of donating platelets (PLTs) and packed red blood cells (PRBCs) on donor's blood cell count, coagulation, PLT function and iron state were analysed. Materials and ...
Kazemi Donna M - - 2012
This study is a baseline analysis of the demographic and behavioral characteristics of freshmen students recruited to enter a longitudinal multi-component intervention program based on the Brief Alcohol Screening, and Intervention for College Students (BASICS) program. The aim of the study was to determine the associations among the participants' gender, ...
Bennett Nicholas J - - 2012
The deprotonation and alkylation of 1-methylcyclohexa-2,5-diene-1-carboxylic acid has been investigated under a range of conditions. In all cases, the formation of compounds was found to be completely stereoselective, although compound was formed as an impurity when alkyl iodides were used as electrophiles, and doubly-alkylated compounds were formed in some cases ...
Gray Nicholas A - - 2012
Background:   Clinical outcomes for patients treated in public and private hospitals may be different. Aim:   To compare the characteristics and outcomes of patients receiving dialysis at public and private hospitals in Queensland. Methods:   Incident adult dialysis patients in Queensland registered with the Australia and New Zealand Dialysis ...
Shinomol George K - - 2012
The present investigation was designed to determine the efficacy of Bacopa monnieri (Brahmi; BM) to offset 3-nitropropionic acid (3-NPA) induced oxidative stress and mitochondrial dysfunction in dopaminergic (N27) cells and prepubertal mouse brain. Pretreatment of N27 cells with BM ethanolic extract (BME) significantly attenuated 3-NPA-induced cytotoxicity. Further, we determined the ...
Granja C - - 2012
Problems survivors face after intensive care unit (ICU) discharge begin while they are still in the ward, where many of their specific problems may run unrecognized, but they assume a heavy weight when they arrive at their homes and face several kind of limitations, from being unable to climb stairs ...
Frankel David S - - 2012
Additional Tachyarrhythmias in IST. Background: Symptom recurrence following sinus node modification (SNM) for inappropriate sinus tachycardia (IST) remains significant despite achieving acute procedural success. The impact of non-IST tachyarrhythmias on symptom recurrence remains poorly characterized. Objectives: The objective was to determine the prevalence and nature of additional tachyarrhythmias preceding and following ...
Gatteschi Dante - - 2012
The comparison of the structural and magnetic properties of molecular nanomagnets (MNM) and magnetic nanoparticles (MNP) can be instructive to get a deeper understanding of the magnetic behavior on the intermediate scale between molecular and bulk objects. In this respect iron oxo based clusters are particularly interesting, since they provide ...
Dal Pan G J - - 2012
Off-label use of medicines is common. Because many off-label uses have not been carefully studied, it is important that postmarketing drug safety systems be able to identify, assess, and monitor adverse events that occur in the off-label setting. The full range of postmarketing surveillance and analysis tools can be utilized ...
Weese Jeffrey Scott - - 2012
Staphylococcal infections are common in veterinary dermatology patients, as are patients whose health status places them at increased risk of staphylococcal infection. The rapid emergence and dissemination of meticillin-resistant staphylococci has had significant impacts on management of infections and also increased concerns about transmission of staphylococci between animals, from animals ...
Teng Kuo-Hsun - - 2012
Abstract A group of prenyltransferases produce linear lipids by catalyzing consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP), a common building block of isoprenoid compounds. Depending on the stereochemistry of the double bonds formed during IPP condensation, these prenyltransferases are categorized as cis- and ...
Huang Zhangjian - - 2012
A series of O(2)-glycosylated diazeniumdiolate-based derivatives of oleanolic acid () were synthesized and their anti-human hepatocellular carcinoma (HCC) activities were evaluated. Compound selectively inhibited HCC, but not non-tumor liver cell proliferation. This inhibition was attributed to high levels of nitric oxide (NO) released in HCC cells. Importantly, exhibited low acute ...
Lee Jung Hyun - - 2012
We suggest copper nanoparticles as a CO(2) carrier by employing the ionic liquid BMIM(+)BF(4)(-) for facilitated transport membranes. The copper nanoparticles were prepared by dissociating the copper metal into the ionic liquid as a facile synthesis. The interactions between BF(4)(-) of the ionic liquid and the surface of copper nanoparticles ...
Zhang Min - - 2012
Restricted mean lifetime is often of direct interest in epidemiologic studies involving censored survival times. Differences in this quantity can be used as a basis for comparing several groups. For example, transplant surgeons, nephrologists, and of course patients are interested in comparing posttransplant lifetimes among various types of kidney transplants ...
McDowell Sean A C - - 2012
A comparative computational study of the cooperative effect of hydrogen-, lithium- and halogen-bonding on model F-H and F-Li complexes with H(2)O was undertaken at the MP2/6-311++G(d,p) level of theory. The general trend of increased attraction or a positive cooperative effect on introduction of a third molecule to the F-H/LiOH(2) dimer ...
Sachse Alexander - - 2012
The metal-organic framework Cu-BTC has been successfully synthesized as nanoparticles inside the mesopores of silica monoliths featuring a homogeneous macropore network enabling the use of Cu-BTC for continuous flow applications in liquid phase with low pressure drop. High productivity was reached with this catalyst for the Friedländer reaction.
Moehrle Matthias - - 2012
  Propranolol has become the treatment of choice of large and complicated infantile hemangiomas. There is a controversy concerning the safety of systemic propranolol. Here we show that topical use of the beta-blocker timolol can also inhibit the growth and promote regression of infantile hemangiomas. In this case series we ...
Ishimoto Ryo - - 2012
Acid assists: The reaction of [{WO(O(2) )(2) }(2) (μ-O)](2-) with 0.5 equivalents of HNO(3) gave a tetranuclear peroxotungstate (1; see picture) that has a dramatically enhanced activity for the epoxidation of cyclooctene with H(2) O(2) compared to various peroxotungstates. The 1-catalyzed system was applicable to the selective oxidation of various ...
Yamamoto Kohta - - 2012
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been considered as a possible therapeutic agent for cancer treatment. This is because of its selective cytotoxicity against various cancer cells without a detrimental effect on normal cells. However, recent studies have reported that the potential application of TRAIL in cancer therapy is ...
Morris J - - 2012
Significant efforts are under way to develop analytic surveillance systems that can leverage observational health-care data to monitor biopharmaceutical products. The systems are being designed to identify safety-related events in a postapproval setting, when the products are already on the market. An additional application of such a system would be ...
< 1 2 3 4 5 6 7 8 9 10 >