Search Results
Results 151 - 200 of 2952
1 2 3 4 5 6 7 8 9 10 >
Borchardt Stefan - - 2012
Objective-To evaluate the use of nonesterified fatty acids (NEFA) and β-hydroxybutyrate (BHBA) concentrations in pooled serum samples for herd-based detection of subclinical ketosis (SCK) in dairy cows after calving. Design-Cross-sectional study. Animals-1,100 dairy cows from 110 herds. Procedures-Blood samples were collected from 10 healthy cows/herd in the first week after ...
Gadó Klára - - 2012
AL amyloidosis is a systemic disease characterised by pathogenetic proteins produced by malignant plasma cells and the deposition of them in different organs of the body. Amyloidogenic protein is the light chain of the monoclonal immunoglobulin, which becomes water insoluble, precipitates and deposites in the extracellular space resulting damage of ...
Koliscak Lindsey - - 2012
Purpose Published evidence on the incidence and predictors of venous thromboembolism (VTE) in patients with cirrhosis of the liver is reviewed. Summary The frequently observed phenomenon of elevated International Normalized Ratio (INR) values in patients with cirrhosis has led to a theory of "autoanticoagulation" and the assertion that such patients ...
Látos Melinda - - 2012
Transplant patients' attitudes and representations related to their illness, their body, and the healing process have a significant impact on their recovery. Aims: The study involved 51 patients from the Department of Surgery, University of Szeged, Hungary. The primary aim was to examine the possible connections between emotional and mood ...
Klosterman Emily S - - 2012
Case Description-An 8-year-old 12.2-kg (26.9-lb) spayed female American Cocker Spaniel was referred for evaluation of abdominal discomfort and a suspected intra-abdominal lipoma with possible invasion into the thorax. Clinical Findings-Physical examination revealed a tense abdomen, and the margins of a large abdominal mass could be appreciated. Abdominal imaging revealed a ...
Kinyó Agnes - - 2012
Allopurinol is an effective urate lowering drug, which is usually well-tolerated with no adverse effects in most cases, but about 2% of the treated patients develop a skin rash, and patients may experience severe allopurinol-induced hypersensitivity syndrome. Aims: The aim of the authors was to summarize and present the clinical ...
Creighton Catherine M - - 2012
Objective-To compare the effect of xylazine bolus versus medetomidine constant rate infusion (MCRI) on serum cortisol and glucose concentrations, urine production, and anesthetic recovery characteristics in dorsally recumbent, spontaneously breathing, isoflurane-anesthetized horses. Design-Prospective, randomized crossover study. Animals-10 healthy Standardbreds. Procedures-Horses were premedicated with xylazine or medetomidine IV. Anesthesia was induced ...
Olivier Heather E - - 2012
Purpose The implementation of a pharmacist-managed clinic based on the Simplified Treatment Intervention to Control Hypertension (STITCH) algorithm is described, with insights on physician acceptance and implementation challenges. Summary After a medical records review indicating gaps in the follow-up care of emergency department (ED) patients found to have elevated blood ...
Kender Zoltán - - 2012
Transient or chronic hyperglycaemia increases the formation of intracellular reactive oxygen species and aldehydes. The accumulation of reactive aldehydes is implicated in the development of diabetic complications. Methylglyoxal, a glucose dependent α-dicarbonyl might be the most important reactive aldehyde in diabetes and its complications. Diabetes was the first disease in ...
Bos Alexandra Squires - - 2012
Objective-To determine accuracy, intermethod agreement, and inter-reviewer agreement for multisequence magnetic resonance imaging (MRI) and 2-view orthogonal myelography in small-breed dogs with first-time intervertebral disk (IVD) extrusion. Design-Prospective evaluation study. Animals-24 dogs with thoracolumbar IVD extrusion. Procedures-Each dog underwent MRI and myelography. Images obtained with each modality were independently evaluated ...
Martello Jay L - - 2012
Purpose The pharmacology, pharmacokinetics, efficacy, safety, dosage, administration, adverse effects, and place in therapy of ecallantide, a kallikrein inhibitor for the treatment of hereditary angioedema (HAE), are reviewed. Summary Ecallantide is the first member of the kallikrein inhibitor class approved for the treatment of acute attacks of HAE. Ecallantide works ...
Radovic-Moreno Aleksandar F - - 2012
Bacteria have shown a remarkable ability to overcome drug therapy if there is a failure to achieve sustained bactericidal concentration or if there is a reduction in activity in situ. The latter can be caused by localized acidity, a phenomenon that can occur as a result of the combined actions ...
Higgins Khadine A - - 2012
RcnR (resistance to cobalt and nickel regulator) is a 40-kDa homotetrameric protein and metalloregulator that controls the transcription of the Co(II) and Ni(II) exporter, RcnAB, by binding to DNA as an apoprotein and releasing DNA in response to specifically binding Co(II) and Ni(II) ions. Using X-ray absorption spectroscopy (XAS) to ...
Yang Kai - - 2012
A nanoscale reduced graphene oxide-iron oxide nanoparticle (RGO-IONP) complex is nonco-valently functionalized with polyethylene glycol (PEG) by Z. Liu and co-workers on page 1868, obtaining a RGO-IONP-PEG nanocomposite which displays excellent physiological stability, strong NIR optical absorbance, and superpara-magnetic properties. This theranostic nanoprobe allows multimodal tumor imaging - in vivo ...
Escudier Bernard - - 2012
In metastatic renal cell carcinoma (mRCC), many factors influence clinical decisions, including histology, tumour burden, prognostic factors, comorbidities, and the ability of the patient to tolerate treatment. Progression-free survival (PFS) durations reported from randomized trials of targeted therapies vary considerably, in part because of differences in patient characteristics. For first-line ...
Nepal Dhriti - - 2012
Colloidal approaches to discrete plasmonic architectures offer numerous advantages with respect to lithography; however, scale-up, purity, and yield has been challenging. Reversibly controlling surface interactions throughout aqueous assembly affords methods that address these challenges. The false-color image illustrates the crude product of soluble, compositionally discrete Au nanorod (50 nm × ...
Wang Xingbao - - 2012
Understanding the transformation mechanism and products of xenobiotics catalyzed by cytochrome P450 enzymes (CYPs) is vital to risk assessment. By density functional theory computation with the B3LYP functional, we simulated the reaction of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) catalyzed by the active species of CYPs (Compound I). The enzymatic and aqueous environments ...
Kota Pradeep - - 2012
Limited proteolysis, accomplished by endopeptidases, is a ubiquitous phenomenon underlying the regulation and activation of many enzymes, receptors, and other proteins synthesized as inactive precursors. Serine proteases make up one of the largest and most conserved families of endopeptidases involved in diverse cellular activities, including wound healing, blood coagulation, and ...
Ruffing Anne M - - 2012
The direct conversion of carbon dioxide into biofuels by photosynthetic microorganisms is a promising alternative energy solution. In this study, a model cyanobacterium, Synechococcus elongatus PCC 7942, is engineered to produce free fatty acids (FFA), potential biodiesel precursors, via gene knockout of the FFA-recycling acyl-ACP synthetase and expression of a ...
Breunig Fábio M - - 2012
Directional effects introduce a variability in reflectance and vegetation index determination, especially when large field-of-view sensors are used (e.g., Moderate Resolution Imaging Spectroradiometer - MODIS). In this study, we evaluated directional effects on MODIS reflectance and four vegetation indices (Normalized Difference Vegetation Index - NDVI; Enhanced Vegetation Index - EVI; ...
Jonnalagadda Venkatadurga - - 2012
The E. coli isopentenyl diphosphate isomerase (IDI) catalyzed reaction of isopentenyl diphosphate (IPP) in D(2)O gives a 66% yield of dimethylallyl diphosphate labeled with deuterium at the (E)-methyl group (d-DMAPP) and a 34% yield of IPP labeled with 1 mol of deuterium at C-2 (d-IPP). This shows that the release ...
Heldwein C G CG Departamento de Farmácia Industrial, Universidade Federal de Santa Maria, RS, - - 2012
The objective of this study was to identify the possible involvement of the GABAergic system in the anesthetic effect of Lippia alba essential oil (EO). We propose a new animal model using silver catfish (Rhamdia quelen) exposed to an anesthetic bath to study the mechanism of action of EO. To ...
Rudd T R TR Istituto di Chimica e Biochimica, Milano, - - 2012
Heparan sulphate (HS) and the related polysaccharide, heparin, exhibit conformational and charge arrangement properties, which provide a degree of redundancy allowing several seemingly distinct sequences to exhibit the same activity. This can also be mimicked by other sulphated polysaccharides, both in overall effect and in the details of interactions and ...
Alouche S R SR Departamento de Fisioterapia, Universidade Cidade de São Paulo, - - 2012
This study investigated the influence of cueing on the performance of untrained and trained complex motor responses. Healthy adults responded to a visual target by performing four sequential movements (complex response) or a single movement (simple response) of their middle finger. A visual cue preceded the target by an interval ...
Mendanha S A SA Instituto de Física, Universidade Federal de Goiás, Goiânia, - - 2012
Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to monitor membrane dynamic changes in erythrocytes subjected to oxidative stress with hydrogen peroxide (H(2)O(2)). The lipid spin label, 5-doxyl stearic acid, responded to dramatic reductions in membrane fluidity, which was correlated with increases in the protein content of the ...
Sun Dao-Cai DC Department of Implant Dentistry, School of Stomatology, Fourth Military Medical University, Xi'an, - - 2012
In order to understand the mechanisms of poor osseointegration following dental implants in type 2 diabetics, it is important to study the biological properties of alveolar bone osteoblasts isolated from these patients. We collected alveolar bone chips under aseptic conditions and cultured them in vitro using the tissue explants adherent ...
Carmo A A AA Laboratório de Instrumentação para Biomecânica, Faculdade de Educação Física, Universidade Estadual de Campinas, SP, Brasil. - - 2012
The aim of this study was to analyze the alterations of arm and leg movements of patients during stroke gait. Joint angles of upper and lower limbs and spatiotemporal variables were evaluated in two groups: hemiparetic group (HG, 14 hemiparetic men, 53 ± 10 years) and control group (CG, 7 ...
Danila Ion - - 2012
The formation of helical self-assembled fibres by a C(3) symmetric molecule incorporating three tetrathiafulvalene units is shown to be influenced dramatically by the processing conditions, leading to a variety of different chiral forms, including unprecedented croissants.
Lee Jung-Jin - - 2012
Morus alba (white mulberry) has been used in traditional Chinese medicine as an anti-headache, diuretic, expectorant, and anti-diabetic agent. In previous studies, extracts of Morus alba demonstrated favorable biological properties, such as antioxidant activity, suppression of lipoxygenase (LOX)-1, cytotoxicity against cancer cells, and inhibition of the invasion and migration of ...
Xu Zhaochao - - 2012
We report a coumarin-derived fluorescent sensor for Zn(2+) termed CTS. CTS shows excellent binding selectivity for Zn(2+) over competing metal ions due to the transformable ability of CTS, that is the displacement of other metal ions by Zn(2+), which induces transformation of chelation from an amide to an imidic acid ...
von Holstein Sarah Linéa - - 2012
Epithelial tumours of the lacrimal gland represent a large spectrum of lesions with similarities in clinical signs and symptoms but with different biological behaviour and prognosis. They are rare, but with aggressive malignant potential. Tumours of the lacrimal gland may present with swelling of the lacrimal gland, displacement of the ...
Hun Kwak Ja - - 2012
H(2)-TPR and FTIR were used to characterize the nature of the Cu ions present in the Cu-SSZ-13 zeolite at different ion exchange levels. The results obtained are consistent with the presence of Cu ions at two distinct cationic positions in the SSZ-13 framework.
Nakazato Michiko - - 2012
Eating disorders (EDs) manifest as abnormal patterns of eating behavior and weight regulation driven by low self-esteem due to weight preoccupation and perceptions toward body weight and shape. Two major groups of such disorders are anorexia nervosa (AN) and bulimia nervosa (BN). The etiology of EDs is complex and evidence ...
Pacha Omar - - 2012
  Ecthyma gangrenosum is the cutaneous manifestation of pseudomonas infection in patients with sepsis. A previously healthy 7-month-old girl who developed ecthyma gangrenosum without apparent inciting factors became neutropenic secondary to autoimmune neutropenia 2 months after initial presentation. She was treated with appropriate surgical and medical intervention and was discharged in ...
Wegner Ingmar - - 2012
BACKGROUND: While electromagnetic tracking (EMT) holds great promise, there are substantiated concerns about interference within the clinical environment. The purpose of this study was to address accuracy and isolate pitfalls for using multiple or adjacent EMT sensors in clinical routine. METHODS: A phantom simulating an EMT-guided puncture of the kidney ...
El Magraoui Fouzi - - 2012
The RING-finger peroxins Pex2p, Pex10p and Pex12p are central components of the peroxisomal matrix protein import machinery. The RING-domain enables each of these proteins to exhibit ubiquitin-protein-ligase (E3) activity, which has been linked to ubiquitin-dependent regulation of the peroxisomal import receptor Pex5p. The RING-peroxins are thought to form a heteromeric ...
Khanna R - - 2012
Background  There has been a significant increase in the prevalence of autism in the USA in the past few decades. The purpose of this study was to provide recent estimates of psychotropic drug use and costs among individuals with autism enrolled in Medicaid programme. Method  A cross-sectional analysis of 2007 ...
Liu J - - 2012
ACCESSIBLE SUMMARY: •  Aggressive behavior is the observable manifestation of aggression and is associated with transitions across different developmental periods as well as a variety of medical and psychiatric disorders. •  This paper provides a brief review of the different biological, social, and environmental risk factors that may predispose individuals ...
Kawai Hiroyuki - - 2012
Ether way: The cinchona-alkaloid-catalyzed title reaction was achieved in high yields with high to excellent ee values for the first time, and affords key intermediates for the biologically important 2 having a trifluoromethylated all-carbon quaternary chiral center. Ether-type catalysts (1) are more efficient in this transformation than the conventional hydroxy ...
Bhat Shailen - - 2012
2'-Aminoacetophenone was chemoselectively alkylated with a range of substituted benzyl, heteroaryl alcohols to afford either the corresponding C- or N- alkylated products in good yield.
Frisk Per - - 2012
Frisk P, Arvidson J, Larsson M, Naessén T. Risk factors for cardiovascular disease are increased in young adults treated with stem cell transplantation during childhood. Abstract:  We measured risk factors for CVD in 18 patients at a median of 18.2 yr after SCT and in sex and age-matched controls. Three patients ...
Chen Zheng - - 2012
Electrical energy storage plays an increasingly important role in modern society. Current energy storage methods are highly dependent on lithium-ion energy storage devices and the expanded use of these technologies is likely to affect existing lithium reserves. The abundance of sodium makes Na-ion based devices very attractive as an alternative, ...
Caron W P - - 2012
Major advances in the field of carrier-mediated agents (CMAs) have revolutionized drug delivery capabilities over the past decade. While providing numerous advantages over their small-molecule counterparts (solubility, duration of exposure, and delivery to the site of action are higher), these agents display substantial variability in systemic clearance (CL) and distribution, ...
Stuart Rhonda L - - 2012
INTRODUCTION:  The prevention and control of transmission of antimicrobial-resistant pathogens in Residential Aged Care Facilities (RACF) is an area that has been neglected yet has significant implications for health services. The aim of this study was to describe the prevalence and appropriateness of antibiotic use within five RACF associated with ...
Terwijn M - - 2012
Introduction:  Immunophenotypic detection of minimal residual disease (MRD) in bone marrow (BM) of acute myeloid leukaemia (AML) patients is of high prognostic relevance. Standard MRD percentage is assessed as a percentage of total white blood cells (WBCs) and is therefore highly dependent on WBC count. Peripheral blood (PB) contains more ...
Patrizi Annalisa - - 2012
  We performed a retrospective study covering a 10-year period (January 1997-January 2007) on children referred to our unit or followed up for Becker's nevus (BN). The aim of this study was to better define the characteristics of BN in childhood, when this hypermelanosis is more frequent than the limited number ...
Sarkar Sougata - - 2012
In the present study, surface-enhanced Raman spectra of a bifunctional Raman reporter, 2-mercaptobenzimidazole, has been found to be responsive exclusively towards Cu(2+) ions while the reporter remains anchored on the Au nanoparticle surface. Thus a specific Cu(2+) -ion-detection protocol emerges. The simplicity, sensitivity, and reproducibility of the method allow routine ...
Nielsen Kim - - 2012
Keratoconus (KC) is one of the leading causes for keratoplasty. While the genetic aetiology of more and more corneal dystrophies is revealed, KC falls behind. And it is not because of lack of effort. The diversity in the many published results from over two decades is discussed in relation to ...
Kaatz Scott - - 2012
The new oral anticoagulants dabigatran, rivaroxaban and apixaban have advantages over warfarin which include no need for laboratory monitoring, less drug-drug interactions and less food-drug interactions. However, there is no established antidote for patients who are bleeding or require emergent surgery and there is a paucity of evidence to guide ...
Liu Qiang - - 2012
No pressure: The oxidation of aromatic CH bonds at room temperature was realized through a copper-catalyzed "oxygenase-type" oxidation of arenes and heteroarenes in the presence of air. The reaction involves an oxygen-atom transfer from O(2) in the air onto the substrates.
1 2 3 4 5 6 7 8 9 10 >