Search Results
Results 501 - 550 of 2952
< 6 7 8 9 10 11 12 13 14 15 16 >
Eddey Philip D - - 2012
This case describes an extrauterine fetus that was discovered in an apparently healthy bitch 5 mo after whelping. The extrauterine fetus was surgically removed, and the bitch made a complete recovery. The topic of canine ectopic pregnancy is discussed, and a review of previously reported cases is presented.
Silbert Benjamin I - - 2012
Background: In medical education, peer-assisted learning (PAL) refers to teaching occurring between fellow students. Few descriptions of its use to teach clinical examination have been published. Student Grand Rounds (SGR) is a student-led initiative whereby senior students volunteer to teach clinical examination to pre-clinical peers. Student tutors attend a modified ...
Xue Mianqi - - 2012
Here we report the successful synthesis of superconducting potassium doped few-layer graphene (K-doped FLG) with a transition temperature of 4.5 K, which is one order of magnitude higher than that observed in the bulk potassium-GIC (graphite intercalation compound), KC8 (Tc = 0.39 K). The realization of super-conductivity in K-doped FLG ...
Feng Xiaoqin - - 2012
Human CAP10-like protein 46 kDa (hCLP46), as a protein O-glucosyltransferase in mammalian cell lines, modifies the epidermal growth factor-like repeat of Notch receptor and regulates Notch signal pathway, which plays a significant role in carcinogenesis of mammalian. O-glucosylation, modified by rumi in drosophila and poglut in mouse to Notch and other ...
Palaninathan S K - - 2012
Transthyretin (TTR), a β-strand rich tetrameric protein present in human serum and cerebrospinal fluid is involved in the transport of thyroxine and retinol binding protein:retinol complex (holo-RBP). TTR forms two T4 binding sites at the center of the dimer-dimer interface and contains holo-RBP binding sites on both faces of the ...
Hemminki K - - 2012
BACKGROUND: Cancer of unknown primary (CUP) is diagnosed at the metastatic stage. We aimed to identify hidden primary cancers in CUP patients by comparison with cancers in family members. We take use of the fact that the cause of death in CUP patients is often coded as the cancer in ...
Saare M - - 2012
BACKGROUNDDe novo somatic copy number aberrations (SCNAs) in eutopic and ectopic endometria are thought to be involved in the pathogenesis of endometriosis. In this study we used, for the first time, high-density single nucleotide polymorphism-array technology for accurate detection of SCNAs, inherited DNA copy number variations (CNVs) and copy-neutral loss ...
Gugiu P Cristian - - 2012
Objective: To evaluate the quality of evidence produced by studies of the chronic care model (CCM). Study Design: Systematic review using a grading system in which grades are assigned on the basis of the hierarchy of evidence, study limitations, and analytical attempts to mitigate limitations. Data Collection: Systematic literature search ...
Ng Ee Ling - - 2012
Lysosomes serve key degradative functions for the turnover of membrane lipids and protein components. Its biogenesis is principally dependent on exocytic traffic from the late endosome via the trans-Golgi network, and it also receives cargo to be degraded from the endocytic pathway. Membrane trafficking to the late endosome-lysosome is tightly ...
Kowalski Dariusz M - - 2012
Background: Chemotherapy is the principal treatment method for patients with advanced non-small-cell lung cancer (NSCLC). Treatment with platinum-based and novel chemotherapeutic regimens, compared to monotherapy, slightly increases the response rates to 20-40%. The predictive and prognostic values of molecular factors are highly variable; however, data on clinical-demographic factors are still ...
Li Xianglin - - 2012
Ordered array of Au semishells on TiO2 spheres with controlled size are prepared by combining the nanosphere self-assembly and atomic layer deposition (ALD). This ordered 2-D structure with designed array of metal nanogaps can be used as ultra-sensitive surface-enhanced Raman scattering (SERS) substrates with high reproducibility and stability. More importantly, ...
Lu Huili - - 2012
Alterations in gene expression after chemotherapy may potentially help to identify mediators that induce suppression or regeneration in bone marrow. This paper reports our observation that the expression of the chemokine Mig (monokine induced by interferon γ) and its receptor CXCR3 was significantly activated in mice following treatment with the ...
Willis Matthew D - - 2012
Background. Although seasonal variation in tuberculosis incidence has been described in several recent studies, the mechanism underlying this seasonality remains unknown. Seasonality of tuberculosis disease may indicate the presence of season-specific risk factors that could potentially be controlled if they were better understood. We conducted this study to determine whether tuberculosis ...
Achemchem F - - 2012
The F420 strain, isolated from raw goat milk and identified as Enterococcus hirae , was selected because of its strong activity against Gram-positive bacteria, including Listeria monocytogenes . Interestingly, the F420 strain lacks the virulence genes and decarboxylase activity of histidine, lysine, and ornithine, and it is susceptible to 11 ...
Yu Miao - - 2012
As the demand for renewable energy resource is growing rapidly worldwide, a variety of energy materials and technologies are being developed. In this review, we aim to summarize recent developments in the state-of-the-art research on energy harvesting technologies such as thin-film Si or Ge, CdTe, GaAs, organic, hybrid, and dye-sensitized ...
Olsen Gavin L - - 2012
A 2.5 yr old sexually intact male vizsla was admitted to the Iowa State University Veterinary Teaching Hospital for persistent diarrhea, weight loss, and panhypoproteinemia. Examination revealed an emaciated condition and melena. Two masses were palpated in the cranial abdomen. Hematology and serum biochemistry exhibited a regenerative anemia and confirmed ...
Sato Yoko - - 2012
Background: Differences in electrical properties between left and right atria (LA and RA) after pulmonary vein isolation (PVI) for atrial fibrillation (AF) are currently poorly understood. Magnetocardiograms were used to investigate the effect of PVI on bi-atrial magnetic field changes and their relationship to clinical outcomes. Methods and Results: This ...
Kazmierski Wieslaw M - - 2012
The macrocyclic urea 2, a byproduct in the synthesis of benzoxaborole 1, was identified to be a novel and potent HCV protease inhibitor. We further explored this motif by synthesizing additional urea-based inhibitors and by characterizing them in replicase HCV protease-resistant mutants assay. Several compounds, exemplified by 12, were found ...
Kohoutek John - - 2012
We report a type of infrared switchable plasmonic quantum cascade laser, in which far field light in the mid-wave infrared (MWIR, 6.1 μm) is modulated by a near field interaction of light in the telecommunications wavelength (1.55 μm). To achieve this all-optical switch, we used cross-polarized bow-tie antennas and a ...
Shi Shi-Hui - - 2012
The combination of a chiral phosphate anion with a silver ion has been demonstrated as a powerful and synergistic ion pair catalyst for the aza-Mannich reaction. A series of valuable quaternary α,β-diamino acid derivatives was obtained in high yield, and with excellent diastereo- (up to 25:1 dr) and enantioselectivity (up ...
Ford Alexander C - - 2012
OBJECTIVES:Most chronic and recurrent gastrointestinal (GI) symptoms in the community are caused by functional GI disorders, such as functional dyspepsia and irritable bowel syndrome (IBS). It is not known, however, whether these conditions affect mortality. We present the results of a large community-based prospective study that examines this issue.METHODS:This was ...
Green Howard J - - 2012
In this study, we hypothesized that athletes involved in 5-6 months of sprint-type training would display higher levels of proteins and processes involved in muscle energy supply and utilization. Tissue was sampled from the vastus lateralis of 13 elite ice hockey players (peak oxygen consumption = 51.8 ± 1.3 mL·kg(-1)·min(-1); mean ± standard error) ...
van Schoor N M - - 2012
Context:To our knowledge, no previous studies examined the longitudinal relationship between vitamin D status and pulmonary function in a population-based sample of older persons.Objective:Our objective was to examine the cross-sectional as well as the longitudinal relationship between vitamin D status and peak expiratory flow rate (PEFR) in a representative sample ...
Gariepy T D - - 2012
Ticks are among the most important vectors of disease in the Northern Hemisphere, and a better understanding of their feeding behaviour and life cycle is critical to the management and control of tick-borne zoonoses. DNA-based tools for the identification of residual bloodmeals in hematophagous arthropods have proven useful in the ...
Mahajan Sanjay K - - 2012
Scrub typhus and leptospirosis are both zoonosis and systemic febrile illnesses with diverse clinical manifestations and they may present with similar signs and symptoms. We present a case of co-infection of scrub typhus and leptospirosis from Himachal Pradesh in the Himalayan region of India.
Domingues Heloisa Maria Bertol - - 2012
A letter sent in 1982 by a group of scientists to the president of Conselho Nacional de Desenvolvimento Científico e Tecnológico appealed for a policy of preservation of Brazilian scientific culture. The name of Carlos Chagas Filho topped the list of signatures thereby proving his commitment to that proposal, the ...
Takeda Takeshi - - 2012
The reaction of allyltitanocenes with five- to seven-membered cyclic enones proceeded with good to high diastereoselectivity depending on the ring size of enones. The stereochemistry of the major isomers produced by the reaction of cinnamyltitanocene was opposite to that of crotyltitanocene.
van Kempen Bob J H - - 2012
PURPOSE: Modeling studies that evaluate statin treatment for the prevention of cardiovascular disease (CVD) use different methods to model the effect of statins. The aim of this study was to evaluate the impact of using different modeling methods on the optimal decision found in such studies. METHODS: We used a ...
Pestana José M - - 2012
BACKGROUND: Consumer awareness regarding the intake of beef of organic origin is strongly associated with the beneficial outcomes to human health, the environment and animal welfare. In this paper the effects of slaughter season and muscle type on the fatty acid composition, conjugated linoleic acid (CLA) isomeric profile, total cholesterol, ...
Gogoll Karsten - - 2012
This work evaluates the transcutaneous in vitro and in vivo immunization efficacy of five commercially available 5% imiquimod containing formulations. Parameters include microscopic analysis, rheological properties, drug permeation across synthetic membranes of molecular weight cutoff 10kDa and ablated murine skin with both, 0.1M HCl and a phthalate buffer pH 3.6 ...
Rachow Andrea - - 2012
Background. Diagnosis and timely treatment of tuberculosis in children is hampered by the absence of fast and reliable tests, especially in the era of human immunodeficiency virus (HIV). The aim of this study was to evaluate the diagnostic performance of the Xpert MTB/RIF assay (Xpert) in children with suspected tuberculosis in ...
Seront E - - 2012
BACKGROUND: This phase II study assessed the safety and efficacy of everolimus, an oral mammalian target of rapamycin inhibitor in advanced transitional carcinoma cell (TCC) after failure of platinum-based therapy. PATIENTS AND METHODS: Thirty-seven patients with advanced TCC received everolimus 10 mg/day until progressive disease (PD) or unacceptable toxicity. The ...
Fiebach Jochen B - - 2012
BACKGROUND AND PURPOSE: Desmoteplase is a novel and highly fibrin-specific thrombolytic agent. Evidence of safety and efficacy was obtained in 2 phase II trials (Desmoteplase In Acute Ischemic Stroke [DIAS] and Desmoteplase for Acute Ischemic Stroke [DEDAS]). The DIAS-2 phase III trial did not replicate the positive phase II efficacy ...
McCally Ryan E - - 2012
A 2 yr old dog presented for dysphagia and coughing secondary to a 4 cm × 4 cm turgid subepiglottic mass. Cervical radiographs, an esophagram, and computed tomography confirmed the presence of a cystic mass that was not intimately associated with any surrounding structures. An incisional biopsy confirmed the cystic ...
Singh Damanpreet - - 2012
Context: The adventitious roots of Ficus religiosa L. (Moraceae) have been extensively used in traditional medicine for treatment of several disorders, including epilepsy. Objective: To investigate the possible anticonvulsant effect of the adventitious roots of Ficus religiosa, and to find the biologically active fraction, to substantiate its traditional use in ...
Rocca B - - 2012
Background: Interindividual variability in response to aspirin has been popularized as "resistance". We hypothesized that faster recovery of platelet cyclooxygenase-1 activity may explain incomplete thromboxane (TX) inhibition during the 24-hour dosing interval. Objective: Characterize the kinetics and determinants of platelet cyclooxygenase-1 recovery in aspirin-treated diabetic and non-diabetic patients. Patients/Methods: One-hundred ...
Lin Jian Hua - - 2012
Objective: To assess whether Chinese manipulation improves pain, function/disability and global perceived effect in adults with acute/subacute/chronic neck pain.Data sources: CAJ Full-text Database (Chinese), Wanfang Database (Chinese), Cochrane Database (English) and Medline (English).Review methods: Literature searching was performed with the following keywords and their combination: 'manual therapy/bone setting/Chinese manipulation', 'neck/cervical ...
Wi Jung-Sub - - 2012
We demonstrate a straightforward method to enlarge the spectral window for broadband interaction with light, by creating a plasmonic nanostructure composed of closely spaced multiple Au nano-disks. The vertically stacked, Au nano-disks of three different sizes make it possible to merge the individual spectral windows of the internal nano-disks into ...
Paterno Josne C - - 2012
Background/Aim: Chronic kidney disease (CKD) is an increasing major public health problem worldwide. The sympathetic nervous system and nitric oxide play an important role in the pathogenesis of CKD. Traditional Chinese medicine has accumulated thousands of years of therapeutic experiences. Electroacupuncture (EA) and moxibustion (MO) are two such therapeutic strategies. ...
Wilson Andrew W - - 2012
• This study uses phylogenetic analysis of the Sclerodermatineae to reconstruct the evolution of ectomycorrhizal host associations in the group using divergence dating, ancestral range and ancestral state reconstructions. • Supermatrix and supertree analysis were used to create the most inclusive phylogeny for the Sclerodermatineae. Divergence dates were estimated in ...
Cutress Mark L - - 2012
What's known on the subject? and What does the study add? Endoscopic management of upper tract urothelial carcinoma (UTUC) using either ureteroscopy and laser ablation, or percutaneous resection, is a management option for treating selected low-grade tumours with favourable characteristics. However, the evidence base for such practice is relatively weak, ...
Almeida Darcy Fontoura de - - 2012
This paper studies the period considered the 'prehistory' of the Instituto de Biofísica, namely between November 1937 and October 1945, during which Carlos Chagas Filho championed the inclusion of scientific research at Universidade do Brasil (UB), despite facing multiple and complex obstacles. The lack of successful precedents at UB isolated ...
Kim Mi-Na - - 2012
Left ventricular (LV) dyssynchrony is often seen in patients with hypertension, even without heart failure. Arterial stiffness is well accepted as an important factor of increasing blood pressure and influencing ventricular function. The purpose of this study was to determine the relationship between aortic stiffness and LV dyssynchrony in hypertensive ...
Ortore G - - 2012
Among the 23 different fibril proteins described in human amyloidosis, transthyretin is associated with the most common hereditary form of the disease and its knowledge is corroborated through about 150 crystal structures in addition to thousands of small ligands tested as fibril formation inhibitors. In spite of the large amount ...
Parmelee Dean X - - 2012
For about a decade, team-based learning (TBL), as an educational strategy, has been growing in use in the US and in several other international medical schools. It is a learner-centered, small group instructional strategy with good academic outcomes and considerable potential to address many of the professional competencies that are ...
Maly Thorsten - - 2012
We demonstrate a 15-fold enhancement of solid-state NMR signals via dynamic nuclear polarization (DNP) based on a stable, naturally occurring radical in a protein: the flavin mononucleotide (FMN) semiquinone of flavodoxin. The linewidth of flavodoxin's EPR signal suggests that the dominant DNP mechanism is the solid effect, consistent with the ...
Nelson-Flower Martha J - - 2012
1. Breeding with kin can reduce individual fitness through the deleterious effects of inbreeding depression. Inbreeding avoidance mechanisms are expected to have developed in most species, and especially in cooperatively breeding species where individuals may delay dispersal until long after sexual maturity. Such potential mechanisms include sex-biased dispersal and avoidance of ...
Pedersen Bente K - - 2012
During the past decade, skeletal muscle has been identified as a secretory organ. Accordingly, we have suggested that cytokines and other peptides that are produced, expressed and released by muscle fibres and exert either autocrine, paracrine or endocrine effects should be classified as myokines. The finding that the muscle secretome ...
Sundborg Eva - - 2012
The aim of this study was to describe the translation and the cross-cultural adaptation process of questionnaire about intimate partner violence (IPV). IPV is a serious threat to women's health. There is a need for instruments to measure the results of educational interventions. The Violence Against Women Health Care Provider ...
Nencetti S - - 2012
Transthyretin is a homotetrameric protein that carries thyroxine and retinol binding protein in plasma and is associated with a variety of amyloid diseases. One approach to the potential treatment of TTR amyloidosis is the stabilization of the native tetramer, over the dissociative transition state, through the binding of small molecules; ...
< 6 7 8 9 10 11 12 13 14 15 16 >