Search Results
Results 301 - 350 of 2109
< 2 3 4 5 6 7 8 9 10 11 12 >
Métras R - - 2012
Highly pathogenic avian influenza HPAI H5N1 was first reported in Africa in 2006, in Nigeria. The country experienced severe outbreaks in 2006 and 2007, strongly affecting the poultry population. Current knowledge on potential risk factors for HPAI H5N1 occurrence in poultry farms in Nigeria is limited. Therefore, we conducted a ...
Shahabadi Nahid - - 2012
The water-soluble complex, [Cu(Val)(2)(NO(3))(2)]; in which Val=valacyclovir, an antiviral drug, has been synthesized and characterized by elemental analysis, furier transfer-infrared, hydrogen nuclear magnetic resonance (H NMR), and UV-Vis techniques. The binding of this Cu (II) complex to calf thymus DNA was investigated using fluorimetry, spectrophotometry, circular dichroism, and viscosimetry. In ...
Liu Gang - - 2012
We report the synthesis of single crystalline Co(2)Si nanowires and the electrical transport studies of single Co(2)Si nanowire devices at low temperature. The butterfly shaped magnetoresistance shows interesting ferromagnetic features, including negative magnetoresistance, hysteretic switch fields, and stepwise drops in magnetoresistance. The nonsmooth stepwise magnetoresistance response is attributed to magnetic ...
Wang Y - - 2012
The infiltration of glioma cells into adjacent tissue is one of the major obstacles in the therapeutic management of malignant brain tumours, in most cases precluding complete surgical resection. Consequently, malignant glioma patients almost invariably experience tumour recurrences. Within the brain, glioma cells migrate rapidly either amoeboidly or mesenchymally to ...
Marsh John E - - 2012
Cognitive control mechanisms-such as inhibition-decrease the likelihood that goal-directed activity is ceded to irrelevant events. Here, we use the action of auditory distraction to show how retrieval from episodic long-term memory is affected by competitor inhibition. Typically, a sequence of to-be-ignored spoken distracters drawn from the same semantic category as ...
Ko Wei-Hsu WH Division of Gastroenterology, Department of Internal Medicine, Shin-Kong Wu Ho-Su Memorial Hospital College of Medicine, Taipei Medical University Division of Biostatistics, Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei Department of Health Care Management, College of Management, Chang Gung University, Tao-Yuan, - - 2012
  In spite of numerous studies on the association between diabetes mellitus (DM) and hepatocellular carcinoma (HCC), the results are inconsistent and whether and how the effect of DM on the risk for HCC is modified or synergistically exerted by hepatitis virus infection are still unclear. We aimed to elucidate ...
Hoffman Gloria E - - 2012
FMR1 premutation (PM) alleles have 55-200 CGG·CCG-repeats in their 5' UTR. PM carriers are at risk of fragile X-associated tremor and ataxia syndrome (FXTAS). Females are also at risk for FX primary ovarian insufficiency (FXPOI). PM pathology is generally attributed to deleterious properties of transcripts with long CGG-tracts. For FXPOI, ...
Bursey Charles R - - 2012
Abstract Paraplesiohedruris ranae n. gen., n. sp. (Ascaridida; Cosmocercoidae; Cosmocercidae) from the large intestine of Hylarana volkerjane (Anura; Ranidae) is described and illustrated. The new genus is assigned to the Cosmocercinae of the Cosmocercidae based on the presence of an esophagus composed of a short pharynx, cylindrical corpus, isthmus and ...
Dasanu Constantin A - - 2012
Tyrosine kinase inhibitors (TKIs) have changed the concepts of systemic therapy for a variety of advanced solid and hematologic malignancies. However, their toxicity can be significant, and includes both cardiac and non-cardiac effects. The authors evaluate comprehensively the adverse cardiovascular portfolio of small molecule TKIs, postulate their underlying mechanisms and ...
Erden Sacide - - 2012
We aimed to determine the prevalence and risk factors of retinopathy in hypertensive outpatients. Demographic data, accompanying diseases, anthropometric measurements, and blood and urine biochemistry of 655 hypertensive patients were evaluated. Hypertensive retinopathy rate was 66.3% (grade 1, 33.6%; grade 2, 32.7%). Age, duration of hypertension, and systolic blood pressure ...
Matsumoto Ayumi - - 2012
Background:  This retrospective study aimed to evaluate the influence of prenatal diagnosis on perinatal outcomes of congenital heart disease (CHD) over a 17-year period at a single center. Methods:  We reviewed the perinatal outcomes of CHD in 146 patients diagnosed by fetal echocardiography between 1994 and 2010. We also analyzed ...
Sharma Gangavaram V M - - 2012
The synthesis of the macrolactone core of (+)-neopeltolide has been achieved. The key synthetic strategy involves the highly diastereoselective synthesis of the 2,6-cis-disubstituted tetrahydropyran ring by a transannular cyclization of δ-hydroxy alkene using mercuric trifluoroacetate. Two of the six stereocenters C-5 and C-11 were realized from l-malic acid, while the ...
Balasubramanian Sowmya - - 2012
Purpose.  Pulmonary vein stenosis (PVS) is a progressive disease that is frequently lethal. We have previously identified neoproliferation of myofibroblasts as the mechanism for progressive intraluminal PVS. PVS occurs in association with other congenital heart diseases (CHD) and in structurally normal hearts. This study sought to describe the spectrum of ...
Tian Cuifeng - - 2012
Self-assembling Au mesoflower arrays are prepared using a polymethylmethacrylate (PMMA) template on an iron substrate via a combined top-down/bottom-up nanofabrication strategy. The PMMA template with the holes around 300-500 nm in diameter is first fabricated by using polymer blend lithography on iron substrates, and the highly homogeneous Au mesoflower arrays with ...
Benesic Andreas - - 2012
Gender, ethnicity and individual differences in hepatic metabolism have major impact on individual drug response, adverse events and attrition rate during drug development. Therefore, there is an urgent need for reliable test systems based on human cells. Yet, the use of primary human hepatocytes (PHHs) is restricted by limited availability, ...
García-Jiménez W L - - 2012
The potential role of wild animals in the maintenance and spread of tuberculosis (TB) infection in domestic livestock is of particular importance in countries where eradication programs have substantially reduced the incidence of bovine tuberculosis but sporadic outbreaks still occur. Mycobacterium bovis is the agent mainly isolated in wildlife in ...
Harp Kathi L H KL Department of Sociology, University of Kentucky, Lexington, Kentucky 40506, USA. - - 2012
Limited research shows that correlates of substance use differ for mothers and nonmothers. This study compares mothers and nonmothers by examining the relationship between perceived social support and frequency of crack/cocaine use. Data for the 307 female prisoners in this sample were collected between 2007 and 2008 in four US ...
Caldwell Christine A - - 2012
It has been proposed that the uniqueness of human cumulative culture may be attributable to humans' greater orientation toward copying the process of behavior (imitation), as compared with the products (emulation), resulting in particularly high fidelity transmission. Following from previous work indicating that adult human participants can exhibit cumulative learning ...
Koo Bonil - - 2012
Material design in terms of their morphologies other than solid nanoparticles can lead to more advanced properties. At the example of iron oxide we explored the electrochemical properties with an application as a cathode and anode of hollow nanoparticles. Such nanoparticles contain very high concentration of cation vacancies that can ...
Khan Munasib - - 2012
Juniperus excelsa Bieb. is used in folk medicine for lowering blood pressure (BP). Its BP-lowering effect, endothelium-dependent and endothelium-independent vasodilator effects, and cardio-modulatory effect are reported here. The crude extract of J. excelsa (Je.Cr) which tested positive for the presence of anthraquinone, flavonoids, saponins, sterols, terpenes, and tannins induced a ...
Chin Yi-Ping - - 2012
Soybean fermentation broth (SFB) exhibits potent antibacterial activity against different species of bacteria in in vitro assays and animal models. Four isoflavone compounds-daidzin, genistin, genistein, and daidzein-of SFB were analyzed and quantified by high-performance liquid chromatography. In the in vitro test, daidzin and daidzein had more potent antibacterial activity than ...
Henne Walter A - - 2012
EC20, a folate-targeted (99m)Tc based radioimaging agent with a high folate receptor (FR) binding affinity, has been used for both the diagnosis and the staging of FR positive malignancies (currently in phase III trials) and also for the localization of inflamed lesions characterized by the accumulation of FR+ macrophages. Because ...
McDonald Andrea M - - 2012
Objectives  To (i) document the incidence of multiplicity in Nigeria, (ii) compare healthcare utilization during pregnancy and at delivery for singleton and multiple pregnancies (iii)and investigate whether antenatal care modifies the relationship between multiplicity and likelihood of having skilled attendance. Methods  This observational study was a secondary analysis of the ...
Bortolatto Cristiani F CF Laboratório de Síntese, Reatividade e Avaliação Farmacológica e Toxicológica de Organocalcogênios, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Santa Maria, CEP, RS, - - 2013
Organoselenium compounds have been described as antioxidant and neuroprotective agents. To evaluate the antioxidant action of 2,2'-dithienyl diselenide (DTDS) and its effects in brain monoamine oxidase (MAO) activity in vitro. Assays for reactive species (RS), lipid peroxidation, protein oxidation, MAO A and B activities in rat brain homogenate as well ...
Schlomer Gabriel L - - 2012
Drawing on the evolutionary terminal investment hypothesis and Trivers' (1974) parent-offspring conflict theory, we advance and evaluate a mediational model specifying why and how maternal age, via mating effort and parental investment, affects mother-child conflict. Data from a longitudinal study of 757 families indicate that (a) older maternal age predicts ...
Ayhan Erkan - - 2012
Hypertension is a known risk factor for coronary artery disease. However, the number of studies focusing on the events following ST elevation myocardial infarction (STEMI) in patients with an antecedent hypertension is limited. Our aim is to evaluate the clinical outcomes of primary angioplasty in STEMI patients with antecedent hypertension ...
Applebaum Allison J AJ Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, 641 Lexington Ave., New York, NY 10022, USA. - - 2012
A strong therapeutic alliance has been found to predict psychotherapeutic treatment success across a variety of therapeutic modalities and patient populations. However, only a few studies have examined therapeutic alliance as a predictor of psychotherapy outcome among cancer survivors, and none have examined this relation in telephone-administered cognitive-behavioral therapy (T-CBT). ...
Yan Shichao - - 2012
The rotation dynamics of single magnesium porphine (MgP) molecules on ultrathin NaCl bilayer is investigated with low temperature scanning tunneling microscopy (STM) and density functional theory (DFT) calculations. It is observed that the rotational oscillation between two stable orientations can be turned on and off by the molecular charge state, ...
Patching Geoffrey R - - 2012
Despite the importance of both response probability and response time for testing models of choice, there is a dearth of chronometric studies examining systematic asymmetries that occur over time- and space-orders in the method of paired comparisons. In this study, systematic asymmetries in discriminating the magnitude of paired visual stimuli ...
Schirhagl Romana - - 2012
Microgravimetric sensors have been developed for detection of insulin by using quartz crystal microbalances as transducers, in combination with sensitive layers. Natural antibodies as coatings were compared with biomimetic materials to fabricate mass-sensitive sensors. For this purpose polyurethane was surface imprinted by insulin which acts as synthetic receptor for reversible ...
Hayward Richard A RA NIHR GP Clinical Lecturer, Arthritis Research UK Primary Care Centre, Keele University, Keele, Staffordshire, UK. - - 2013
Engagement of general practitioners (GPs) and recruitment of patients are ever present problems in primary care studies. This paper seeks to demonstrate that electronic prompts represent one method of easing the burden on GPs to recruit individual patients to studies and also provide the opportunity to collect research data during ...
Treasure Janet - - 2012
Treasure J. Coherence and other autistic spectrum traits and eating disorders: Building from mechanism to treatment. The Birgit Olsson lecture. Nord J Psychiatry 2012; Early Online:1-5. Aim: To revisit Gillberg's hypothesis proposed in 1992, which was that anorexia nervosa should be considered within the spectrum of autistic disorders. Method: A ...
Cartwright Colleen - - 2012
There is little understanding in Australia of the special issues faced by gay, lesbian, bisexual and transgender people in end-of-life care and advance care planning. This exploratory study aimed to achieve an initial understanding of these issues to inform the development of a larger study involving gay, lesbian, bisexual and ...
Schroden Jonathan J - - 2012
The reactions of neutral ground-state yttrium (Y) atoms with 1,3- and 1,4-cyclohexadiene (CHD) were studied using crossed molecular beams. Formation of YC(6)H(6) + H(2) and YH(2) + C(6)H(6) was observed for both isomers at collision energies (E(coll)) of 31.3 and 13.0 kcal/mol. Measured product branching ratios at E(coll) = 31.3 ...
Levin Andrew - - 2012
To date, few studies have examined mental health consequences among attorneys exposed to clients' traumatic experiences. A longitudinal, 2-wave, cross-lagged study was used in a cohort of attorneys (N = 107) from the Wisconsin State Public Defender's Office. We assessed changes in posttraumatic stress disorder (PTSD), depression, and functional impairment ...
Daniel Christoph - - 2012
Mesangial cell (MC) migration is essential during glomerular repair and kidney development. The aim of the study was to identify marker/player for glomerular progenitor/reserve cells migrating into the glomerulus after MC injury and during glomerulogenesis in the rat. Experimental mesangial proliferative nephritis was induced in Sprague Dawley rats by intravenous ...
Wong Yetta K - - 2012
Visual perceptual learning (PL) and perceptual expertise (PE) traditionally lead to different training effects and recruit different brain areas, but reasons for these differences are largely unknown. Here, we tested how the learning history influences visual object representations. Two groups were trained with tasks typically used in PL or PE ...
Zanaletti Riccardo - - 2012
Alpha-7 nicotinic acetylcholine receptors (α7 nAChR) are implicated in the modulation of many cognitive functions such as attention, working and episodic memory, for this reason α7 nAChR agonists represent promising therapeutic candidates for the treatment of cognitive impairment associated with with Alzheimer's disease (AD) and schizophrenia. A medicinal chemistry effort, ...
Garcia Agustin A AA Kenneth Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA. - - 2012
To evaluate the activity of gemcitabine and docetaxel in patients with recurrent ovarian cancer. Patients with platinum-resistant disease and prior treatment with paclitaxel received treatment with docetaxel on day 1 and gemcitabine on days 1 and 8, repeated every three weeks. Twenty patients, with a platinum-free interval of three months, ...
Cabe Patrick A - - 2012
Four experiments examined haptic perception of two distal spatial properties in a bypass event. A hook suspended a string held taut between the participant's finger and a weight. Moving their fingers laterally beneath the hook, participants estimated the finger's point of closest approach (PCA) to the hook and bypass distance ...
Jensen Michael D - - 2012
Respiratory motion may lead to dose errors when treating thoracic and abdominal tumours with radiotherapy. The interplay between complex multileaf collimator patterns and patient respiratory motion could result in unintuitive dose changes. We have developed a treatment reconstruction simulation computer code that accounts for interplay effects by combining multileaf collimator ...
Boei Jan J W A - - 2012
The recent steep increase in population dose from radiation-based medical diagnostics, such as computed tomography (CT) scans, requires insight into human health risks, especially in terms of cancer development. Since the induction of genetic damage is considered a prominent cause underlying the carcinogenic potential of ionizing radiation, we quantified the ...
Pan Jie - - 2012
WW domain-containing transcription regulator 1 (WWTR1) was initially identified as a transcriptional coactivator involved in the differentiation of stem cells as well as the development of multiple organs. Recently, WWTR1 has also been identified as a major component of the novel Hippo signalling pathway important for the development of breast ...
Yamase Toshihiro - - 2012
Ferromagnetic [n-BuNH(3)](12)[(CuCl)(6)(SbW(9)O(33))(2)]·6H(2)O (1) and antiferromagnetic [n-BuNH(3)](12)[(MnCl)(6)(AsW(9)O(33))(2)]·6H(2)O (4) have been synthesized and structurally and magnetically characterized. Two complexes are structural analogues of [n-BuNH(3)](12)[(CuCl)(6)(AsW(9)O(33))(2)]·6H(2)O (2) and [n-BuNH(3)](12)[(MnCl)(6)(SbW(9)O(33))(2)]·6H(2)O (3) with their ferromagnetic interactions, first reported by us in 2006. (1) When variable temperature (T) direct current (dc) magnetic susceptibility (χ(M)) data are analyzed ...
Alikhani N N Division of Endocrinology, Diabetes and Bone Diseases, The Samuel Bronfman Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, - - 2013
Dyslipidemia has been associated with an increased risk for developing cancer. However, the implicated mechanisms are largely unknown. To explore the role of dyslipidemia in breast cancer growth and metastasis, we used the apolipoprotein E (ApoE) knockout mice (ApoE(-/-)), which exhibit marked dyslipidemia, with elevated circulating cholesterol and triglyceride levels ...
Waligórska Anna - - 2012
Background:  The efficacy of early intervention programs for children with autism has been emphasized in many studies. However, access people with autism to professional services in Poland is very limited and the burden of supporting child's development often falls on parents, especially in families with low socio-economical status and families ...
Wang Yu - - 2012
Syntheses, structures, and properties of univalent coinage metal 2-methylimidazolate supramolecular isomers [M(mim)] (1, M = Cu; 2, M = Ag) were investigated in detail. In addition to the known isomers, namely, zigzag chains [Cu(mim)] (1a) and [Ag(mim)] (2a), molecular octagon [Cu(8)(mim)(8)]·C(6)H(6) (1b), decagon [Cu(10)(mim)(10)]·C(8)H(10) (1c), helical chain [Ag(4)(mim)(4)]·C(6)H(6) (2b), and ...
Chaung Wayne W WW The Feinstein Institute for Medical Research, Manhasset, NY 11030, - - 2012
Endogenous molecules released by dying cells [i.e., damage-associated molecular patterns (DAMPs)] after trauma and severe blood loss can activate pattern recognition receptors, leading to a cascade of inflammatory responses and organ injury. Mitochondrial transcription factor A (TFAM) is a transcription factor for mitochondrial DNA. TFAM is structurally related to high ...
Alafeefy Ahmed M - - 2012
Abstract New series of quinazoline containing sulfonamide derivatives were prepared and screened for their antitumor activity. Four human cancer cell lines, namely, hepatoma cancer cell line (HepG2), breast cancer cell line (MCF-7), cervix cancer cell line (HeLa) and colon cancer cell line (HCT-8), were used to measure the cytotoxic activity. ...
Skinner Robin - - 2012
Suicide is the second leading cause of death for young Canadians (10-19 years of age)--a disturbing trend that has shown little improvement in recent years. Our objective was to examine suicide trends among Canadian children and adolescents. We conducted a retrospective analysis of standardized suicide rates using Statistics Canada mortality ...
< 2 3 4 5 6 7 8 9 10 11 12 >