Search Results
Results 51 - 100 of 2109
1 2 3 4 5 6 7 8 9 10 >
Vanhorne-Sealy Jama - - 2012
ABSTRACT: The Medical Radiobiology Advisory Team (MRAT) is the operations arm of the Armed Forces Radiobiology Research Institute (AFRRI), located at Naval Support Activity in Bethesda, MD. AFRRI is internationally recognized as expert in the biological effects of ionizing radiation research, training, and mitigation. During the U.S. Department of Defense's ...
Fuks David D Department of Digestive Surgery, Jules Verne University of Picardy, Amiens, - - 2012
Liver cirrhosis is considered to be a contraindication for pancreaticoduodenectomy (PD). The aim of this study was to present 4 cases of successful PD in cirrhotic patients. Among the charts of 90 patients who underwent PD between 2004 and 2008, 4 patients with liver cirrhosis were retrospectively reviewed. There were ...
Musolino Stephen V - - 2012
ABSTRACT: Emergency responders from the Department of Energy are trained regularly to assess the environmental consequences of a radiological or nuclear incident. While drills and exercises are highly effective tools in rehearsing for an emergency, the accidents at the Fukushima Daiichi Nuclear Power Plants presented real-world complexities that are difficult ...
Shimura Tatsuo - - 2012
Background/Aims: The aim of this paper is to examine the safety and feasibility of pylorus-preserving pancreaticoduodenectomy in elderly patients. Methodology: The study population consisted of 40 consecutive patients. They were divided into two groups: Group A (<75 years old) and Group B (=75 years old). Reconstruction with a vertical duodenojejunostomy ...
Lou Yu-Feng - - 2012
Background/Aims: HBV-related acute-on-chronic liver failure (AoCLF) is associated with a high mortality rate. An artificial liver support system (ALSS) is a newly emerging therapeutic option, which can be implemented in routine patient care. In order to determine if any pretreatment immunological parameter could be an indicator to evaluate immune states ...
Craddock Susan - - 2012
Tuberculosis poses one of the biggest threats to individuals living with HIV in most low-income regions of the world, and the increase of multi-drug resistant tuberculosis (MDR-TB) in South Africa, Eastern Europe, and elsewhere makes this threat that much more critical. Despite the extent of the problem, new drugs for ...
Shivathirthan Nairuthya - - 2012
For resection of advanced hepatocellular carcinoma (HCC) in which tumor thrombus (TT) extends into inferior vena cava (IVC) or right atrium (RA) surgery is challenging and requires skillful techniques. Here, we report a case of recurrent HCC with TT extending to the RA, who underwent successful resection with tumor thrombectomy ...
Piecuch Jerzy - - 2012
Background/Aims: The aim of the study was to analyze the mortality and symptomatic anastomotic leak following stapled anastomosis after anterior resection for rectal cancer. Methodology: We analyzed retrospectively 161 patients subjected to elective anterior resection of the rectum. There were 102 (63.3%) men and 59 (37.7%) women. The patients were ...
Cohn Randy M - - 2012
The extreme range of motion at the shoulder, high velocities and stresses, and repetitive nature of the throwing motion place the throwing athlete at risk for a wide range of pathologic entities. The treating orthopedist must fully understand the biomechanics of the throwing cycle and how it contributes to the ...
Smith J J - - 2012
Present quality of life instruments for inflammatory bowel disease do not evaluate many social aspects of patients' lives that are potentially important in clinical decision making. We have developed a new Social Impact of Chronic Conditions - Inflammatory Bowel Disease (SICC-IBD) questionnaire to assess these areas. A 34-item questionnaire was ...
Katayose Yu - - 2012
Gemcitabine is widely used as a first-line therapy for biliary tract cancer (BTC). However, few studies have been conducted to analyze second- line therapies. From 33 patients who had been administered gemcitabine following resection between May 2005 and August 2007, we retrospectively analyzed the safety and efficacy of S-1 in ...
Jakab Ferenc - - 2012
Background/Aims: Transverse hepatectomy, removal of hepatic segments IVB, V, VI, (III) in continuity with the gallbladder through the transverse portal plane, was first introduced by Paul Sugarbaker in 1990. In 1995 the first transverse hepatectomy in Hungary was carried out by our workgroup. This article summarizes our experience with transverse ...
Tupin Edward A - - 2012
ABSTRACT: During the spring of 2011, the U.S. Environmental Protection Agency (EPA) used its national radiation monitoring and sampling system, RadNet, to detect, identify, and inform the public about radioactive material in the United States resulting from Japan's Fukushima Daiichi Nuclear Power Plant release. The RadNet system monitors ambient air, ...
Zhang Ming - - 2012
Background/Aims: This study gives insight into survival predictors and clinicopathological features of carcinoma of the gastric cardia. Methodology: The study included 233 patients who underwent operation for carcinoma of the gastric cardia. Clinicopathological prognostic variables were evaluated as predictors of long-term survival by univariate and multivariate analysis. Cox regression was ...
Macrì Antonio - - 2012
Background/Aims: To evaluate the role of the hepatic perfusion in the assessment of the colorectal cancer. Methodology: For this research 18 patients affected by colorectal cancer were enrolled. All the patients were submitted to the evaluation of the Doppler Perfusion Index (DPI) which represents the ratio of hepatic arterial to ...
Restivo A - - 2012
Patients with lung metastasis from colorectal cancer (CRC) may benefit from surgical resection. Chest computed tomography (CT) is often included in the preoperative staging. Interpretation of the nature of pulmonary lesions is not always easy and many question its clinical value. Clinical data for all patients treated at our institution ...
Yamada Atsuo - - 2012
Background/Aims: Capsule endoscopy (CE) has high positive (95%) and negative predictive values (83- 100%) for the bleeding source in patients with obscure gastrointestinal bleeding (OGIB) but the diagnostic yield is influenced by the timing of the examination and the nature of the bleeding. Methodology: We investigated the role of early ...
Yokoo Hideki - - 2012
Background/Aims: Many kinds of transection devices have been developed but there are very few reports on the effectiveness of using ultrasonically activated scalpel with a hook blade in combination with a thermo-coagulating device for hepatectomy. Methodology: We studied 533 consecutive patients who underwent hepatectomy for primary disease and for living- ...
Hong Sung Pil - - 2012
Background/Aims: Although capsule endoscopy (CE) is widely used to evaluate small bowel diseases, its diagnostic power has not been firmly established. The aim of this study was to compare the abilities of the "Miro- Cam" and "PillCam SB" to detect Z-line and duodenal papillae. Methodology: The records of 141 patients ...
Cuschieri Joseph - - 2012
To determine and compare outcomes with accepted benchmarks in trauma care at 7 academic level I trauma centers in which patients were treated on the basis of a series of standard operating procedures (SOPs). Injury remains the leading cause of death for those younger than 45 years. This study describes ...
Romanyukha Alexander - - 2012
ABSTRACT: After the 9.0 magnitude earthquake and subsequent massive tsunami on 11 March 2011 in Japan, several reactors at the Fukushima Daiichi Nuclear Power Plant suffered severe damage. There was immediate participation of U.S. Navy vessels and other United States Department of Defense (DoD) teams that were already in the ...
Kitagawa Maki - - 2012
Background/Aims: To determine the safety and the efficacy of total pancreatectomy for the curative treatment of pancreatic carcinoma. Methodology: Retrospective analysis was performed using 10 patients receiving total pancreatectomy. Results: The median duration of the operative procedure was 8.7 hours and the median estimated blood loss was 2,700mL. Seven patients ...
Lyons Craig - - 2012
ABSTRACT: The U.S. Department of Energy/National Nuclear Security Administration's (DOE/NNSA) Aerial Measuring System (AMS) deployed personnel and equipment to partner with the U.S. Forces in Japan (USFJ) to conduct multiple aerial radiological surveys. These were the first and most comprehensive sources of actionable information for U.S. interests in Japan and ...
Oida Takatsugu T Department of Surgery, Yokohama Central Hospital, Yokohama, Japan. - - 2012
Marginal ulceration and delayed gastric emptying are considerable problems after pancreaticoduodenectomy. Helicobacter pylori (HP) are well known to be associated with gastritis, gastric ulcer and gastric cancer. Thus, we studied the relationship between marginal ulceration and delayed gastric emptying in the early postoperative period after pancreaticoduodenectomy with pancreaticogastrostomy. We retrospectively ...
Oida Takatsugu - - 2012
Background/Aims: A high incidence of hyperbilirubinemia and an increased incidence of gallbladder disorders after esophagectomy have been reported. Moreover, several studies have documented an increased incidence of gallbladder disease in patients receiving long-term total parenteral nutrition. We studied the incidence of cholecystitis and cholestasis and hyperbilirubinemia associated with total parenteral ...
Gerstein Neal Stuart - - 2012
To provide an evidence-based focused review of aspirin use in the perioperative period along with an in-depth discussion of the considerations and risks associated with its preoperative withdrawal. For patients with established cardiovascular disease, taking aspirin is considered a critical therapy. The cessation of aspirin can cause a platelet rebound ...
Ni Jingmei - - 2012
Background/Aims: Increased production of reactive oxygen species, which cause oxidative DNA damage, is considered to be related to gastric carcinogenesis. The aim of this research was to detect the 8-OHdG and the expression of hOGG1and MnSOD, in human gastric mucosa with chronic atrophic gastritis (CAG) and gastric carcinoma (GC) comparing ...
O'Reilly Elma A - - 2012
Laparoscopic inguinal hernia repair (LIHR), using a transabdominal preperitoneal (TAPP) or totally extraperitoneal (TEP) technique, is an alternative to conventional open inguinal hernia repair (OIHR). A consensus on outcomes of LIHR when compared with OIHR for primary, unilateral, inguinal hernia has not been reached. Perform a meta-analysis of all randomized ...
Suehiro Taketoshi - - 2012
Background/Aims: We summarize data of patients with gastrointestinal bleeding (GIB) and discuss the relationship between antithrombotic drug use and age in patients with GIB. Methodology: One-hundred and twenty patients with GIB were divided into two groups according to age (=75 years old and <75 years old). The causes and clinical ...
Huang Brady K - - 2012
The anatomic and histologic descriptions of the rotator cuff tendons and footprints are continuously evolving, and new discoveries have led to novel concepts in our understanding of rotator cuff tendon pathology. These concepts may be translated into the analysis of these footprints with imaging methods, particularly magnetic resonance imaging.
Clark Brian C - - 2012
Dynapenia (pronounced dahy-nuh-pē-nē-a, Greek translation for poverty of strength, power, or force) is the age-associated loss of muscle strength that is not caused by neurologic or muscular diseases. Dynapenia predisposes older adults to an increased risk for functional limitations and mortality. For the past several decades, the literature has largely ...
Morimura Ryo - - 2012
Background/Aims: Repeat hepatectomy is widely accepted as a treatment for primary or metastatic liver malignancy. However, it entails a longer operative time and is associated with additional operative risks. The goal of the present study was to evaluate the impact of previous hepatectomy on the short-term outcomes of repeat hepatectomy, ...
Miller Charles W - - 2012
ABSTRACT: On 11 March 2011, northern Japan was rocked by first a magnitude 9.0 earthquake off the eastern coast and then an ensuing tsunami. The Fukushima Daiichi Nuclear Power Plant complex was hit by these twin disasters, and a cascade of events was initiated that led to radionuclide releases causing ...
Lv Sheng-Xiang - - 2012
Background/Aims: To assess the incidence of gastric cancer development in gastric benign ulcer patients and to evaluate the value of biopsy by taking specimens from both the base and edges of ulcers in contrast to the traditional biopsy which takes specimens from the edges of ulcers only. Methodology: An endoscopic ...
Zhou Li L Department of General Surgery, Peking Union Medical College, Beijing, China. - - 2012
The significance of preoperative serum a-fetoprotein (AFP) level in hepatocellular carcinoma (HCC) treated with different modalities remains controversial. Besides, many cut-off values have been used. The present study aims to clarify significance of two major ones in HCC with cirrhosis. One hundred and thirty eight consecutive cirrhotic patients with HCC ...
Masuda Toshiro - - 2012
Background/Aims: To investigate the efficacy and the safety of a hybrid ablation combining a percutaneous and endoscopic approach for multi-nodular hepatocellular carcinomas. Methodology: Hybrid ablation consists of a percutaneous approach for deep-sited tumors and an endoscopic approach for superficial ones. Between January 1991 and December 2007, fortyeight patients with 139 ...
Fujiwara Shozo - - 2012
Background/Aims: It remains unclear whether synchronous, multiple, early gastric cancers can be radically resected with endoscopic resection. Methodology: Patients who underwent gastrectomy for early gastric cancer were included in this study and divided into two groups: a solitary gastric cancer group and a multiple gastric cancer group. The clinicopathological features ...
Otani Kazuhiro - - 2012
Background/Aims: The aim of this study was to clarify the role of bile duct resection without hepatectomy (hilar resection) in hilar cholangiocarcinoma. Methodology: We retrospectively compared surgical results for hilar cholangiocarcinoma between 8 patients treated with hilar resection and 21 patients treated with hepatectomy. Results: All hilar resections were performed ...
Chang Wai Keat WK Department of Surgery, South Auckland Clinical School, Middlemore Hospital, University of Auckland, Otahuhu, Auckland, New Zealand. - - 2012
To determine the efficacy and safety of triclosan-impregnated sutures. Surgical-site infections (SSIs) produce considerable morbidity and increase health care costs. A potential strategy to decrease the rates of SSIs may be the use of triclosan-impregnated sutures. These have been endorsed and/or funded by professional and governmental bodies in numerous countries. ...
Sharma Kavita - - 2012
Exercise stress testing is the most commonly used noninvasive method to evaluate for coronary artery disease in men and women. Although emphasis has been placed on the diagnostic value of ST-segment depression, the exercise stress test provides other valuable diagnostic and prognostic data, beyond ST-segment depression. The value of these ...
Yamashita Shin-Ichi - - 2012
Spontaneous rupture of the esophagus (Boerhaave's syndrome) is a critical disease. Most patients should undergo surgery for primary closure and drainage of the mediastinum and thorax. We treated a total of 7 cases of spontaneous rupture of the esophagus between December 2000 and August 2007. The time delay was 3 ...
Spiliotis John - - 2012
Background/Aims: Pseudomyxoma peritonei syndrome (PMP) may be associated with slow "benign" or malignant process. However, the natural history of this disease is slow progression to death. Its treatment is variable and controversial. In this current study we have compared the patients with Pseudomyxoma peritonei syndrome with recurrences due to the ...
Kim In-Wha - - 2012
The purpose of this study was to identify and characterize the association of various clinical variables and CYP3A5 genotypes with the pharmacokinetics of tacrolimus and outcome over 1-5 years in kidney transplantation patients in Korea. A total of 129 recipients (aged 18-65 years) administered tacrolimus were genotyped for CYP3A5 (6986A>G ...
Dineen Thomas A TA Chemical Research and Discovery, Amgen Inc., 360 Binney Street, Cambridge, Massachusetts 02142, United States. - - 2012
We have previously shown that hydroxyethylamines can be potent inhibitors of the BACE1 enzyme and that the generation of BACE1 inhibitors with CYP 3A4 inhibitory activities in this scaffold affords compounds (e.g., 1) with sufficient bioavailability and pharmacokinetic profiles to reduce central amyloid-β peptide (Aβ) levels in wild-type rats following ...
Ongarora Benson G - - 2012
Four phthalocyanine (Pc)-peptide conjugates designed to target the epidermal growth factor receptor (EGFR) were synthesized and evaluated in vitro using four cell lines: human carcinoma A431 and HEp2, human colorectal HT-29, and kidney Vero (negative control) cells. Two peptide ligands for EGFR were investigated: EGFR-L1 and -L2, bearing 6 and ...
Chang Andrew T - - 2012
Although the fate of most tRNA molecules in the cell is aminoacylation and delivery to the ribosome, some tRNAs are destined to fulfill other functional roles. In addition to their central role in translation, tRNA molecules participate in processes such as regulation of gene expression, bacterial cell wall biosynthesis, viral ...
Bhattacharjee Somnath S Department of Chemistry, Michigan State University , East Lansing, Michigan 48824, United - - 2012
Layer-by-layer polyelectrolyte adsorption is a simple, convenient method for introducing ion-exchange sites in porous membranes. This study demonstrates that adsorption of poly(acrylic acid) (PAA)-containing films at pH 3 rather than pH 5 increases the protein-binding capacity of such polyelectrolyte-modified membranes 3-6-fold. The low adsorption pH generates a high density of ...
Kim Hyunjung - - 2012
Chemical investigation of the cultured cyanobacterium Fischerella sp. (SAG strain number 46.79) led to the isolation of four nitrile-containing indole alkaloids, namely 12-epi-fischerindole I nitrile (1), deschloro 12-epi-fischerindole I nitrile (2), 12-epi-fischerindole W nitrile (3), and deschloro 12-epi-fischerindole W nitrile (4) along with a known metabolite hapalosin. The structures were ...
Chan K L Andrew - - 2012
Rapid, in situ, and label-free chemical analysis in microfluidic devices is highly desirable. FT-IR spectroscopic imaging has previously been shown to be a powerful tool to visualize the distribution of different chemicals in flows in a microfluidic device at near video rate imaging speed without tracers or dyes. This paper ...
Natesan Senthil - - 2012
We present the cellular quantitative structure-activity relationship (cell-QSAR) concept that adapts ligand-based and receptor-based 3D-QSAR methods for use with cell-level activities. The unknown intracellular drug disposition is accounted for by the disposition function (DF), a model-based, nonlinear function of a drug's lipophilicity, acidity, and other properties. We conceptually combined the ...
1 2 3 4 5 6 7 8 9 10 >