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Results 401 - 450 of 5011
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Diniz Michele B - - 2012
The authors conducted an in vivo study to determine clinical cutoffs for a laser fluorescence (LF) device, an LF pen and a fluorescence camera (FC), as well as to evaluate the clinical performance of these methods and conventional methods in detecting occlusal caries in permanent teeth by using the histologic ...
Keating Gillian M - - 2012
Oral bazedoxifene (Conbriza®) reduces the incidence of new vertebral fractures in patients with postmenopausal osteoporosis. It also appears to reduce the risk of nonvertebral fractures in high-risk patients. Bazedoxifene is generally well tolerated and does not appear to have detrimental effects on endometrial or breast tissue.
Ma Long - - 2012
To systematically review the literature to determine the effects of intensive versus normal glycaemic control during peri-operative period on prognosis of patients undergoing cardiac surgery. The literature was systematically reviewed based on searching criteria established by Cochrane Collaboration. PubMed database searching was conducted for literature and the language was limited ...
Patel Kaushik P - - 2012
Significance: The renin-angiotensin system (RAS) plays an important role in the normal control of cardiovascular and renal function in the healthy state and is a contributing factor in the development and progression of various types of cardiovascular diseases (CVD), including hypertension, diabetes and heart failure, in the disease state. Recent ...
Iles Ross Anthony - - 2012
Objectives This study aimed to determine whether a multi-faceted model of management of work related musculoskeletal disorders reduced compensation claim costs and days of compensation for injured workers. Methods An intervention including early reporting, employee centred case management and removal of barriers to return to work was instituted in 16 ...
Zhao Yan - - 2012
In this study, we report the functionalization of silica nanoparticles with highly photoreactive phenyl azido groups and their utility as a negatively charged building block for layer-by-layer (LbL) electrostatic assembly to produce a stable silica nanoparticle coating. Azido-terminated silica nanoparticles were prepared by the functionalization of bare silica nanoparticles with ...
Thompson Richard B - - 2012
Abstract This article provides a concise review of the use of magnetic resonance imaging (MRI) for measurement of regional aerosol deposition in the lungs. Basic aspects of MRI and its use in lung imaging and measurement of regional ventilation are introduced. Imaging of hydrogen protons (water) and inhaled hyperpolarized gases ...
Kong Cheng-Jiang - - 2012
C9, a component of the membrane attack complex, participates in the final stage of the complement cascade which lyses foreign organisms by disrupting the integrity of their cell membranes. In the present study, a full-length ayu C9 (aC9) cDNA was cloned which contains 2,125 nucleotides and encodes a protein of ...
Tünnermann Henrik - - 2012
Coherent beam combining enables power scaling beyond the limits of single amplifiers. Therefore, improving the performance and simplicity of coherent combination techniques is of great interest for many high power applications. Here, we show all-fiber coherent beam combining of two ytterbium doped amplifiers with and without a dedicated phase actuator ...
Squassina Alessio - - 2012
The Golden Helix Pharmacogenomics Days are high-profile international educational scientific meetings discussing pharmacogenomics and personalized medicine. Here, we provide an overview of the scientific lectures and the topics discussed during the 4th Golden Helix Pharmacogenomics Day, held in Cagliari, Italy, on 7 October 2011, and the 5th Golden Helix Pharmacogenomics ...
Spasovski Goce - - 2012
Organ donation and transplantation activity in the majority of Balkan countries (Albania, Bosnia and Herzegovina, Croatia, Macedonia, Moldova, Montenegro, Serbia, Romania and Bulgaria) are lagging far behind international averages. Inadequate financial resources, unclear regional data and lack of government infrastructure are some of the issues which should be recognized to ...
Chiu Rossa W K - - 2012
Noninvasive prenatal diagnosis of fetal Down syndrome using direct nucleic acid analysis was once an elusive goal. The presence of cell-free fetal DNA in maternal plasma was discovered in 1997 and offered a new noninvasive source of fetal genetic material. A number of approaches have since been developed for the ...
Ramírez Julio - - 2012
OBJECTIVE: The efficacy of antibody-based biological therapies currently used in psoriatic arthritis (PsA) depends not only on their blocking effect on the targeted molecule but also on their binding affinity to genetically defined variants of cell-surface Fc-γ receptors. Our objective was to assess the potential influence of functionally relevant FCGR2A/CD32A ...
Eisenstein Diana Hill - - 2012
Many people receiving maintenance anticoagulation therapy require surgery each year in ambulatory surgery centers. National safety organizations focus attention toward improving anticoagulation management, and the American College of Chest Physicians has established guidelines for appropriate anticoagulation management to balance the risk of thromboembolism when warfarin is discontinued with the risk ...
John Cynthia Cindi A - - 2012
Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome are secondary events that affect patients with traumatic brain injury. All 3 syndromes affect both sodium and water balance; however, they have differences in pathophysiology, diagnosis, and treatment. Differentiating between hypernatremia (central neurogenic diabetes insipidus) ...
Zhukovsky Donna S - - 2012
PC-FACS (Fast Article Critical Summaries for Clinicians in Palliative Care), an electronic publication of the American Academy of Hospice and Palliative Medicine, provides palliative care clinicians with concise summaries of the most important findings from more than 50 medical and scientific journals. Each month, structured summaries and insightful commentaries on 6-10 ...
Al-Saleh Mohammed A Q - - 2012
Although electromyography (EMG) has been used extensively in dentistry to assess masticatory muscle impairments in several conditions, especially temporomandibular disorders (TMDs), many investigators have questioned its psychometric properties and accuracy in diagnosing TMD. The authors conducted a systematic review to analyze the literature critically and determine the accuracy of EMG ...
Ran Ke - - 2012
To investigate the changes in protein of myocardium after hydrogen sulfide delayed preconditioning by using proteomics technology. Sixteen Sprague-Dawley rats were randomly assigned to control (group S) or hydrogen sulfide group (group H), n = 8 for each group. Myocardial ischemia/reperfusion injury model (ischemia 30 minutes followed by reperfusion 120 ...
Kalyani Manjula Ishwara - - 2012
In diseases such as cancer, induction of apoptosis has been a new target for mechanism-based drug discovery. The central component of the process of apoptosis is a proteolytic system involving a family of proteases called caspases. Apoptosis involves characteristic morphological and biochemical events ultimately leading to cell demise. Apoptotic induction ...
Hansch Andreas - - 2012
OBJECTIVE: To assess the feasibility of time-resolved parallel three-dimensional magnetic resonance imaging (MRI) for quantitative analysis of pulmonary perfusion using a blood pool contrast agent. METHODS: Quantitative perfusion analysis was performed using novel software to assess pulmonary blood flow (PBF), pulmonary blood volume (PBV) and mean transit time (MTT) in ...
- - 2012
We sought to provide evidence-based guidelines for utilization of Doppler studies for fetuses with intrauterine growth restriction (IUGR). Relevant documents were identified using PubMed (US National Library of Medicine, 1983 through 2011) publications, written in English, which describe the peripartum outcomes of IUGR according to Doppler assessment of umbilical arterial, ...
Grünheid Thorsten - - 2012
Cone-beam computed tomography (CBCT) has become a routine imaging modality for many orthodontic clinics. However, questions remain about the amount of radiation patients are exposed to during the scans. This study determined the amounts of radiation potentially absorbed by a patient during orthodontic imaging with a CBCT machine with various ...
Ortmann Amanda J - - 2012
This is a case report of a 53-yr-old female who experienced sudden sensorineural hearing loss (SSNHL) accompanied by roaring tinnitus in her right ear. The patient's hearing partially improved in the low frequencies in response to intratympanic injections. Given that her hearing loss did not improve further, the patient was ...
Sunamura M - - 2012
In bypass-grafted arteries, anastomotic intimal hyperplasia develops more markedly at the distal junction than the proximal one. It is likely that it arises from the difference in flow patterns at these two sites. Therefore we have studied the relationship between the flow patterns and precise locations of wall thickening specific ...
Borhani-Haghighi Afshin - - 2012
To investigate the safety, tolerability, and short-term efficacy of treatment with erythropoietin in patients with optic neuritis as a first demyelination event. We conducted this randomized double-blind pilot study in the Shiraz University of Medical Sciences, Shiraz, Iran, from March 2007 to January 2009. The participants were patients aged 18-45 ...
Pemán Javier - - 2012
The management of invasive fungal infections in critically ill patients, from diagnosis to selection of the ther- apeutic protocol, is often a challenge. Early diagnosis and treatment are associated with a better prognosis, but apart from cases with positive cultures from blood or fluid/tissue biopsy, diagnosis is neither sensitive nor ...
McClamrock Howard D - - 2012
Ovarian stimulation and intrauterine insemination (OS/IUI), a mainstay of current infertility therapy and a common antecedent to IVF, is a significant driver of the multiple births epidemic. Redress of this challenge, now marking its quarter centennial, will require a rethinking of current practice patterns. Herein we explore prospects for prevention, ...
Guo Li-Yun - - 2012
Glaucoma is a typical irreversible blind neurodegenerative disease for which there is no effective treatment for halting visual deterioration. The recent development of neural stem cells studies sheds light on a potential resolution for this disease. As a result, an appropriate glaucoma modeling method for stem cell transplantation study is ...
Poh Paula Y S - - 2012
Orthostatic hypotension (OH) occurs among several populations; elevated temperatures increase an individual's susceptibility, whereas the effect of sleep loss (SL) remains inconclusive. The purpose was: 1) to evaluate the effects of 10 d of heat acclimation (HA) and 28 h of SL on OH; and 2) to determine the best ...
Di Raimondo D - - 2012
Walking is a very acceptable form of aerobic exercise. Several trials have demonstrated significant benefits of fast walking on the risk factors of cardiovascular disease, particularly for hypertension. Aim of our study was to assess whether physical activity obtained through fast walking might lead to a different reduction of blood ...
Shalabney A - - 2012
We show that adding a thin dielectric layer with high refractive index on top of the metallic layer in surface plasmon resonance sensors in the Kretschmann-Raether configuration in the spectral mode causes a redshift of the resonance wavelength, narrowing of the resonance dip, and an enhancement to the spectral sensitivity. ...
Martin Jérôme - - 2012
We show both numerically and experimentally that intense, narrow, and low-divergence beams of light are produced at the apex of dielectric pyramid-shaped microtips. These beams exhibit a Bessel transverse profile but are narrower than the usual Bessel beam, allowing for a significant enhancement of the light intensity inside the beam. ...
Angileri Filippo F - - 2012
Object Telemedicine provides a new approach to improve stroke care in community settings, delivering acute stroke expertise to hospitals in rural areas. Given the controversies in many aspects of the treatment of intracerebral hemorrhage (ICH) and the lack of guidelines, a prompt neurosurgical second opinion may facilitate the treatment of ...
Ho Sherry S Y - - 2012
Rapid molecular prenatal diagnostic methods, such as fluorescence in situ hybridization (FISH), quantitative fluorescence-PCR, and multiplex ligation-dependent probe amplification, can detect common fetal aneuploidies within 24 to 48 h. However, specific diagnosis or aneuploidy exclusion should be ideally available within the same day as fetal sampling to alleviate parental anxiety. Microfluidic ...
Cheung Kenneth M C - - 2012
STUDY DESIGN.: A cross-sectional, population-based cohort study. OBJECTIVE.: The objective of this study was to evaluate the clinical relevance of skipped level disc degeneration (SLDD) to that of contiguous, multilevel disc degeneration (CMDD) of the lumbar spine. The study also aimed to identify patterns of SLDD, its classification, prevalence, and ...
Lederer Valérie - - 2012
Objective To assess the differential effect of personal and work-related psychosocial, physical and organizational determinants by gender on time to return-to-work (RTW) following long-term disability. Methods Data come from a larger study conducted in the province of Quebec, Canada. A cohort of 455 adults on long-term disability due to work-related ...
Kaoutar B - - 2012
Social and health data on the immigrant population remain scarce in France, especially concerning those in irregular situation. The Baudelaire outpatient clinic in Saint- Antoine hospital in Paris (PASS, i.e. specific free medicosocial care for the poor, the uninsured or the undocumented patients) treats a majority of immigrants, a lot ...
Reid Greg - - 2012
Professional practice guided by the best research evidence is a usually referred to as evidence-based practice. The aim of the present paper is to describe five fundamental beliefs of adapted physical activity practices that should be considered in an 8-step research model to create evidence-based research in adapted physical activity. ...
Lusardi Paula - - 2012
Applying the best evidence to support nursing practice and generating new knowledge for use in practice are the hallmarks of excellence and allow practitioners to meet patient care quality and safety priorities. Although identifying a patient care problem comes easily to staff nurses, the process of clarifying the problem and ...
McQueen Peter - - 2012
Evaluation of: Stephanowitz H, Lange S, Lang D et al. Improved two-dimensional reversed phase-reversed phase LC-MS/MS approach for identification of peptide-protein interactions. J. Proteome Res. 11(2), 1175-1183 (2011). Recent developments in bottom-up proteomics have supplanted the use of gel-based approaches in favor of multidimensional chromatographic separations of peptide mixtures followed ...
Borges-Sá Marcio - - 2012
Invasive fungal infection (IFI) is an entity that encompasses different types of infections caused by different types of those fungi pathogenic for humans. In the setting of critically ill patients with multiple and oftenconcurrent risk factors and comorbidities the most common are those caused by the Candida and Aspergillus species. ...
Gutierrez Marwin - - 2012
OBJECTIVE: To test the learning curve of rheumatologists with different experience in videocapillaroscopy (VCP) attending an intensive training program focused on interpretation of the main capillary nailfold abnormalities, the scleroderma (systemic sclerosis, SSc) pattern, and the normal pattern, and to determine their interreader agreement with an experienced investigator. METHODS: Five ...
Lopes Filho Hibernon - - 2012
The aims of this study were to evaluate the optical properties of esthetic brackets and determine their influence on visual perception. Eighty esthetic brackets of 16 commercial brands were tested. The color and translucency of the brackets, as well as the color of the maxillary central incisors of 40 subjects, ...
Johnson Lynt B - - 2012
Laparoscopic-assisted hepatic resection (LAHR) has been described as a safe and reliable means of liver resection for tumors or live-donor hepatectomy. Here we compare the outcomes in paired cohorts between patients undergoing open hepatic resection (OHR) and LAHR. Two hundred and twelve patients who underwent either OHR or LAHR from ...
Alvarez-Lerma Francisco - - 2012
In non-immunocompromised patients admitted to intensive care departments or units (ICU), it is difficult to establish a definitive diagnosis of pulmonary aspergillosis because the signs and symptoms of this infectious disease are non-specific, and serological techniques are not very specific as well. For this reason, a diagnosis of possible pulmonary ...
Goronzy Jörg J - - 2012
Age is an important risk for autoimmunity, and many autoimmune diseases preferentially occur in the second half of adulthood when immune competence has declined and thymic T cell generation has ceased. Many tolerance checkpoints have to fail for an autoimmune disease to develop, and several of those are susceptible to ...
You Kug-Ho - - 2012
This case report describes the treatment of a 16-year-old girl with ankylosed maxillary central incisors that were noticeably infraoccluded and labially displaced. We performed a segmental osteotomy with an autogenous bone graft in a single-stage surgery to align and level the ankylosed teeth. The dento-osseous segment was successfully repositioned with ...
Robichaux Catherine - - 2012
Acute and critical care nurses routinely encounter ethical "quandaries" such as providing perceived futile care. Other everyday ethically important occurrences may go unrecognized, however, thus diminishing their importance to moral nursing practice. This column presents a framework that may assist in developing specific skills to recognize and engage in both ...
Ward Stephanie A - - 2012
The role of aspirin in the secondary prevention of occlusive cardiovascular events has now been well established. Given this, aspirin in primary prevention has been the focus of several large trials and subsequent meta-analyses over the past 3 decades, and yet the issue remains controversial. Recent studies in populations with ...
Zielinski Christina E - - 2012
IL-17-producing CD4(+) T helper cells (T(H)17) have been extensively investigated in mouse models of autoimmunity. However, the requirements for differentiation and the properties of pathogen-induced human T(H)17 cells remain poorly defined. Using an approach that combines the in vitro priming of naive T cells with the ex vivo analysis of ...
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