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Results 401 - 450 of 5011
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Mandolfino T - - 2012
Distal bypass has been considered as a primary choice for the treatment of critical limb ischemia (CLI). When bypass failed with limb threatening ischemia, the amputation rate is high in patients with increased surgical risks and lack of conduit. Percutaneous transluminal angioplasty (PTA) has been shown to be effective and ...
Yu Jin-Lu - - 2012
To study the features and approaches of endovascular treatment for intracranial aneurysms with a ruptured bleb. This retrospective study was carried out from June 2007 to June 2009 in Jilin University, Jilin, China. Thirty patients with intracranial aneurysms with ruptured blebs were included. The aneurysms were diagnosed by digital subtraction ...
Torigoe Keiichiro - - 2012
Hemangiopericytoma develops from many organs. In the central nervous system, most tumors arise in the intracranial portion, and tumors originating from the spinal cord are rare. Its clinical course and neurological characteristics have not been disclosed. We present a case of a 51-year-old woman with gradually progressing paraparesis. Magnetic resonance ...
Segall Marc - - 2012
Permanent binary phase masks with planar surfaces and high tolerance to laser radiation are recorded in the volume of photo-thermo-refractive glass using the contact copying technique and binary amplitude master masks. Conversion of a Gaussian beam to higher order modes is shown.
Beitz Janice M - - 2012
Negative pressure wound therapy (NPWT) is used extensively in the management of acute and chronic wounds, but concerns persist about its efficacy, effectiveness, and safety. Available guidelines and algorithms are wound type-specific, not evidence-based, and many lack clearly described relative and absolute contraindications and stop criteria. The purpose of this ...
Faas Brigitte Hw - - 2012
We evaluated both clinical and laboratory aspects of our new strategy offering quantitative fluorescence (QF)-PCR followed by non-targeted whole genome 250K single-nucleotide polymorphism array analysis instead of routine karyotyping for prenatal diagnosis of fetuses with structural anomalies. Upon the detection of structural fetal anomalies, parents were offered a choice between ...
Ma Jie-Fei - - 2012
To investigate the changes in serum malondialdehyde (MDA), interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), aspartate aminotransferase (AST) and creatinine (Cr) after the reproduction of ischemia/reperfusion (I/R) injury model, and the protective effects of liver and kidney with Xuebijing injection on acute I/R injury in rabbits. Sixty rabbits were divided into ...
Sartore Giovanni - - 2012
Glucose variability has recently been investigated in diabetic patients in several studies, but most of them considered only a few variability indicators and did not systematically correlate them with patients' HbA1c levels and other important characteristics. In thus study, the correlations between HbA1c levels and metabolic control (average glucose, AG), ...
Chen Shaopeng S Key Laboratory for Protein and Peptide Pharmaceuticals, National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, - - 2012
Activation-induced cytidine deaminase (AID) is required for the generation of antibody diversity through initiating both somatic hypermutation (SHM) and class switch recombination. A few research groups have successfully used the feature of AID for generating mutant libraries in directed evolution of target proteins in B cells in vitro. B cells, ...
Shi Xinghua - - 2012
A major hurdle for molecular mechanistic studies of many proteins is the lack of a general method for fluorescence labeling with high efficiency, specificity and speed. By incorporating an aldehyde motif genetically into a protein and improving the labeling kinetics substantially under mild conditions, we achieved fast, site-specific labeling of ...
Wilson Gail - - 2012
The nursing shortage triggered by retiring nurses is expected to affect all areas of nursing but particularly specialized nursing areas, such as perioperative units. In addition, the perioperative environment is a difficult place for novice nurses to fit in. Many factors contribute to making the OR environment stressful, and novice ...
Cerci Vladimir - - 2012
An adolescent boy with an Angle Class II Division 1 malocclusion had a hyperdivergent growth pattern with an excessive lower facial height and an anterior open bite. Combined orthodontic and surgical treatment should be considered for patients with a skeletal anterior open-bite malocclusion. For patients who do not want surgery, ...
Bian Hui - - 2012
In this study, the 5 d and 7 d training paradigms were adopted to investigate the influences of different training procedures on the performance of spatial learning and memory of the hippocampal injured rats. The results showed that during the hidden-platform acquisition training, similar spatial learning dysfunctions were indicated in ...
Butler Javed J Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA, - - 2012
Aldosterone antagonists (or mineralocorticoid receptor antagonists [MRAs]) are guideline-recommended therapy for patients with moderate to severe heart failure (HF) symptoms and reduced left ventricular ejection fraction (LVEF), and in postmyocardial infarction patients with HF. The Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure (EMPHASIS-HF) trial evaluated the ...
Hang Jun - - 2012
ssRNA viruses have high levels of genomic divergence, which can lead to difficulty in genomic characterization of new viruses using traditional PCR amplification and sequencing methods. In this study, random reverse transcription, anchored random PCR amplification, and high-throughput pyrosequencing were used to identify orthobunyavirus sequences from total RNA extracted from ...
Velázquez-Ibarra L - - 2012
An experimental study of the effects of an auxiliary 976 nm pump signal on the four-wave mixing parametric bands generated with a 1064 nm pump in a normal dispersion Er-doped photonic crystal fiber is presented. The four-wave mixing signal and idler bands shift to shorter and longer wavelengths, respectively, with ...
Bu Tong-liang - - 2012
As a component of diesel exhaust particles, 3-methyl-4-nitrophenol (4-nitro-m-cresol, PNMC) is also a metabolite of the insecticide fenitrothion and imposes hazardous effects on human health. In the present study, the alleviative effect of a common antioxidant flavonoid quercetin on mouse germ cells intoxicated by PNMC was investigated. Results showed that ...
Kalpoe Jayant S - - 2012
Resistant bacterial infections are important causes of morbidity and mortality after liver transplantation (LT). This was a retrospective cohort study evaluating the outcomes associated with carbapenem-resistant Klebsiella pneumoniae (CRKP) infections after LT. In a 2005-2006 cohort of 175 consecutive LT recipients, 91 infection episodes were observed in 61 patients (35%). ...
Hamada Akinobu - - 2012
We analyzed the association of ABCB1 polymorphisms with erlotinib-induced toxicity and the pharmacokinetics in patients with non-small-cell lung cancer. After erlotinib 150 mg was administered to 50 patients, ABCB1 polymorphisms were analyzed via either TaqMan(®) assays or direct nucleotide sequencing. Plasma concentrations were measured by HPLC. The trough concentration at ...
Tournis Symeon - - 2012
OBJECTIVE: To investigate the effect of rheumatoid arthritis (RA) on volumetric bone mineral density (vBMD) and bone geometry in postmenopausal women treated with bisphosphonates. METHODS: Fifty-three postmenopausal women with RA and 87 control subjects, comparable in terms of age, body mass index, and years since menopause, underwent peripheral quantitative computed ...
Lowry Gregory Victor - - 2012
Transformations and long-term fate of engineered nanomaterials must be measured in realistic complex natural systems to accurately assess the risks that they may pose. Here, we determine the long-term behavior of poly(vinylpyrrolidone)-coated silver nanoparticles (AgNPs) in freshwater mesocosms simulating an emergent wetland environment. AgNPs were either applied to the water ...
Sumino Kaharu - - 2012
The methacholine challenge test (MCT) is commonly used to assess airway hyperresponsiveness, but the diagnostic characteristics have not been well studied in asthmatic patients receiving controller medications after the use of high-potency inhaled corticosteroids became common. We investigated the ability of the MCT to differentiate participants with a physician's diagnosis ...
Günes Mutlu - - 2012
The study aimed to retrospectively evaluate the reliability of the diagnostic and location tests in Cushing's Syndrome (CS). Eighty-seven patients diagnosed with CS between 1995 and 2007 by Endocrinology Metabolism Department of Cerrahpasa Medical School were included in the study. The control group consisted of 91 patients who presented to ...
Gilbert Sharon A - - 2012
The purpose of this study was to determine outcomes, after the use of propensity score techniques, to create balanced groups according to whether a woman undergoes elective repeat cesarean delivery (ERCD) or trial of labor (TOL). Women who were eligible for a TOL with 1 previous low transverse incision were ...
Liu Xiao-Fen - - 2012
The olfactory system may play a pivotal role in drug addiction. To clarify the issues, we investigated the morphine dependence and psychological craving in morphine addicted mice using the conditioned place preference (CPP) paradigm by taking an only odor cue as the conditioned stimulus (CS). The results showed that by ...
Kim H K - - 2012
Although atherosclerosis remains the most common cause of lower limb ischemia, cystic adventitial disease (CAD) must be considered in the differential diagnosis of a patient without risk factors for atherosclerosis. The disease typically produces lower limb claudication and usually affects young and middle-aged men. The treatment consists of interposition grafting ...
Ghaffarinejad Ali R - - 2012
Periodic catatonia (PC) is a rare type of catatonia syndrome, in which the catatonic phases often repeat regularly. Between the catatonic periods, the symptoms totally disappear and make the diagnosis difficult. We report a case with PC who did not show any catatonic symptoms except anxiety and restlessness in his ...
Lan Tzu-Hsiang - - 2012
This Letter presents a scheme to embed both angular/spectral surface plasmon resonance (SPR) in a unique far-field rainbow feature by tightly focusing (effective NA=1.45) a polychromatic radially polarized beam on an Au (20  nm)/SiO<sub>2</sub> (500  nm)/Au (20  nm) sandwich structure. Without the need for angular or spectral scanning, the virtual spectral probe snapshots a wide operation ...
Maseda Emilio - - 2012
Candida peritonitis in postoperative patients is an independent predictor of mortality. Empirical early antifungal therapy should be started in these patients, since according to the results of studies in patients with candidemia, this has an impact on the prognosis. The treatment recommended by clinical practice guidelines in patients with haemodynamic ...
Ibrahim Michael - - 2012
Ca(2+)-induced Ca(2+) release (CICR) is critical for contraction in cardiomyocytes. The transverse (t)-tubule system guarantees the proximity of the triggers for Ca(2+) release [L-type Ca(2+) channel, dihydropyridine receptors (DHPRs)] and the sarcoplasmic reticulum Ca(2+) release channels [ryanodine receptors (RyRs)]. Transverse tubule disruption occurs early in heart failure (HF). Clinical studies ...
Brown Peter I - - 2012
Respiratory muscle work limits high-intensity exercise tolerance in healthy human beings. Emerging evidence suggests similar limitations exist during submaximal work in some physically demanding occupations. In an occupational setting, heavy loads are routinely carried upon the trunk in the form of body armor, backpacks, and/or compressed air cylinders by military, ...
Falkensammer J - - 2012
Constant-load treadmill testing is frequently used to estimate walking ability of patients with peripheral arterial disease and to assess changes in functional capacity following therapeutic interventions or through disease progression. The value of this test has frequently been disputed based on doubts concerning its reproducibility. The aim of this study ...
Babtain Fawzi A - - 2012
Epilepsy is commonly encountered in neurology practice, affecting more than 50 million people worldwide, according to the World Health Organization reports. Management of women with epilepsy requires attention to some considerations including the hormonal changes and its impact on epilepsy, the interaction between oral contraceptives and antiepileptic drugs (AEDs), pregnancy, ...
Tanei Takafumi - - 2012
Spinal cord stimulation (SCS) has become the preferred option for neurosurgical management of several intractable pains. To evaluate effects of dual lead SCS using two quad leads for central post-stroke pain (CPSP), we retrospectively reviewed eight consecutive patients with CPSP who underwent SCS. Six (75%) of eight patients obtained more ...
Lai Jui-Yu - - 2012
We proposed and experimentally demonstrated the iterative domino algorithm to optimize optical superlattice with >10<sup>5</sup> unit blocks to achieve arbitrary target phase-matching power spectrum. This scheme can achieve unprecedented overall conversion efficiency and spectral fidelity with extremely high computation efficiency.
Zhao Pu - - 2012
We implemented a singly resonant optical parametric oscillator based on adhesive-free-bonded periodically inverted KTiOPO<sub>4</sub> plates. It has major advantages such as walk-off compensation and oscillation at four wavelengths. The threshold of the oscillation was measured to be 8  MW/cm<sup>2</sup>, which is about a factor of 4 lower than that based in ...
Smith Edward R - - 2012
Moyamoya is a progressive arteriopathy of unknown origin affecting the branches of the internal carotid artery (ICA). The arteriopathy can present as an isolated medical condition, affecting both sides of the brain ("moyamoya disease") or can be unilateral or found in association with systemic disorders ("moyamoya syndrome"). The ischemia resulting ...
Shaffer Lisa G - - 2012
To understand the prenatal referral patterns from the United States, Canada, and Israel for two whole-genome microarray platforms, each with a different resolution. Physicians selected one of the two array designs to be performed on 1483 prenatal specimens for a 1-year period. We retrospectively examined detection rates, indications for study, ...
Zhao Xiao-Qi - - 2012
To evaluate the effectiveness of mild hypothermia on low cardiac output in patients after cardiac surgery. Twelve patients manifesting low cardiac output after cardiac surgery despite of the use of massive doses of catecholamine and intra-aortic balloon pump (IABP) underwent mild hypothermia during May 2009 to February 2011. Changes in ...
Erwan Edi - - 2012
Intracerebroventricular (i.c.v.) administration of L: -aspartate (L: -Asp) attenuates stress responses in neonatal chicks, but the mechanism has not been clarified. In the present study, three behavioral experiments were carried out under socially isolated stressful conditions exacerbated by the use of corticotrophin-releasing factor (CRF). In Experiment 1, i.c.v. injection of ...
Kwon Hee Jung - - 2012
To evaluate the effects of transpupillary thermotherapy and intravitreal bevacizumab injection on serous macular detachment and cystoid macular edema (CME) associated with circumscribed choroidal hemangioma. Retrospective, interventional case series. We reviewed the records of 12 patients with circumscribed choroidal hemangioma treated with transpupillary thermotherapy and/or intravitreal injection of bevacizumab. We ...
Sun Shulin - - 2012
The arbitrary control of electromagnetic waves is a key aim of photonic research. Although, for example, the control of freely propagating waves (PWs; refs , , , , , ) and surface waves (SWs; refs , , , ) has separately become possible using transformation optics and metamaterials, a bridge linking both ...
Li Song - - 2012
The present study revisited the controversial taxonomic status of Petaurista yunanensis, P. philippensis, P. hainana, and P. petaurista by using a considerably extended set of morphometrical characters (26 cranial variables from 60 adult specimen skulls). The results revealed no sexual dimorphism in any of the four species but confirmed significant ...
Abt Elliot - - 2012
To understand research and develop skills in adopting research findings, clinicians must overcome a series of challenges. First is determining exactly what constitutes evidence-based care. The amount of often contradictory research findings and "expert" opinion that is available can be overwhelming and should not always be taken as best evidence. ...
Chen Zhi - - 2012
To assess the feasibility and result of endovascular treatments for ruptured peripheral intracranial aneurysms. We retrospectively reviewed our experience and results of endovascular treatments for a series of 18 consecutive patients with ruptured distal intracranial aneurysms at the Department of Neurosurgery, Southwest Hospital, Chongqing, China between January 2005 and June ...
Fisher Benjamin A BA Kennedy Institute of Rheumatology, Imperial College London, London, UK. - - 2012
To examine fine specificity of anticitrullinated peptide antibodies (ACPA) in relation to responsiveness to anti-tumor necrosis factor (anti-TNF) agents in rheumatoid arthritis (RA). Samples from 450 patients with RA treated with anti-TNF agents were analyzed for antibodies to citrullinated α-enolase, vimentin, and fibrinogen peptides. The Disease Activity Score-28 was measured ...
Attreed Matthew M Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, - - 2012
Modification patterns of heparan sulfate coordinate protein function in metazoans, yet in vivo imaging of such non-genetically encoded structures has been impossible. Here we report a transgenic method in Caenorhabditis elegans that allows direct live imaging of specific heparan sulfate modification patterns. This experimental approach reveals a dynamic and cell-specific ...
Chung Charles C - - 2012
Genome-wide association studies of prostate cancer have identified single nucleotide polymorphism (SNP) markers in a region of chromosome 11q13.3 in men of European decent. A fine-mapping analysis with tag SNPs in the cancer genetic markers of susceptibility study identified three independent loci, marked by rs10896438, rs12793759, and rs10896449. This study ...
Liu Te-Chun - - 2012
The miniscrew has been developed and effectively used as orthodontic anchorage, but current studies of its usage are insufficient to provide information about the underlying mechanical mechanisms. The aim of this study was to investigate the roles of bone quality, loading conditions, screw effects, and implanted depth on the biomechanics ...
Southworth Sheri L - - 2012
A process change with the goal of decreasing and ultimately eliminating bloodstream infections associated with central catheters in critical care patients was implemented at Riverside Methodist Hospital. This process of implementation resulted in a culture change in the hospital's medical surgical intensive care unit. Keys to success included a multidisciplinary ...
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