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Liu Zhen - - 2012
Magnetic hybrid hydrogels with a novel polymeric coating consisting of chitosan and cellulose were prepared. By coating cellulose and chitosan, we combined the renewability and biocompatibility of cellulose and chitosan as well as the magnetic properties of Fe(3)O(4) to create a hybrid system to adsorb heavy metals.
Huang Eric Yi-Hsiu - - 2012
PURPOSE: To review the perioperative and follow-up outcomes of patients undergoing radical cystectomy with orthotopic neobladder reconstruction for bladder cancer after prior radical prostatectomy (RP) for prostate cancer. METHODS: A retrospective review of more than 1,900 patients treated with radical cystectomy at USC between 1990 and 2011 was conducted. Fifty-six ...
Roa J J - - 2012
In the last years, Nanoindentation or Instrumented Indentation Technique has become a powerful tool to study the mechanical properties at micro/nanometric scale (commonly the hardness, Elastic modulus and the stress-strain curve). In this review, the different contact mechanisms (elastic and elasto-plastic)are discussed,the recent patentsfor each mechanism (elastic and elato-plastic)are summarized ...
Carlomagno Teresa - - 2012
Covering: up to 2011Natural products are of tremendous importance in both traditional and modern medicine. For medicinal chemistry natural products represent a challenge, as their chemical synthesis and modification are complex processes, which require many, often stereo-selective, synthetic steps. A prerequisite for the design of analogs of natural products, with ...
Zhao Jingjin - - 2012
A simple label-free fluorescent sensing scheme for sensitive and selective detection of nicotinamide adenine dinucleotide (NAD(+)) has been developed based on DNA ligation reaction with ligand-responsive quadruplex formation. This approach can detect 0.5 nM NAD(+) with high selectivity against other NAD(+) analogs.
Zang Yongyuan - - 2012
Electrical and thermal properties of a carbon nanotube (CNT)/multiferroic BiFeO(3) (BFO)/Pt photovoltaic heterojunction are investigated for the first time. Enhanced photovoltaic properties (J(sc) ≈ 2.1 μA cm(-2) and V(oc) ≈ 0.47 V), as compared to the traditional polycrystalline BFO with indium tin oxide (ITO) as the top electrode, are observed ...
Chung E - - 2012
PURPOSE: To evaluate the clinical outcomes of penile prosthesis implantation for the treatment for erectile dysfunction (ED) over 3 decades in a centre of excellence. METHODS: A total of 955 penile prostheses were implanted between June 1981 and June 2010. The mean age of the men was 53.2 (28-80) years, ...
Maruthavanan T - - 2012
A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7-12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7-12) were assayed for antibacterial, antifungal and anthelmintic activities and they exhibited significant results.
Hawkins Summer Sherburne - - 2012
To examine the impact of cigarette excise taxes and smoke-free legislation on tobacco use among households with school-age children and adolescents as well as disparities in children's secondhand smoke exposure. We compare the results from models using causal inference techniques to those from cross-sectional models. We linked families of 6-17-year-olds ...
Hellmuth Marc - - 2012
Orthology detection is an important problem in comparative and evolutionary genomics and, consequently, a variety of orthology detection methods have been devised in recent years. Although many of these methods are dependent on generating gene and/or species trees, it has been shown that orthology can be estimated at acceptable levels ...
Kwitko Sérgio - - 2012
BACKGROUND: Precise IOL calculation in post-refractive surgery patients is still a challenge for the cataract surgeon. The purpose of this study is to test whether adding Orbscan II values into the double-K method improves IOL calculation in this group of patients. METHODS: A prospective study with 43 eyes previously submitted ...
Wiser Amir - - 2012
Objective: To evaluate if monitoring patients by ultrasound (US) only during in vitro fertilization (IVF) treatment is safe. Design: Randomized prospective study. Intervention: Patients undergoing their first IVF treatment were randomized into two groups. The ultrasound only group (study group) was monitored by US for follicle size and endometrial thickness ...
Hauglann Beate - - 2012
PURPOSE: The aims of this cohort study were to explore various longitudinal aspects of employment and disability pension due to permanently reduced work ability among women with breast cancer and to investigate the impact of breast cancer on income. PATIENTS AND METHODS: In a national register-based controlled cohort study from ...
Bangert Mathieu - - 2012
New treatments against severe bacterial infections are needed because the response to antibiotic treatment is slow in acute settings and is becoming less effective owing to the emergence of antibiotic-resistant pathogens. P4-mediated antibody therapy offers a unique treatment strategy that combines exogenous immunoglobulin with the immunoactivating peptide P4. In an ...
Vazquez B N - - 2012
CD69 is one of the earliest proteins expressed after leukocyte activation and its engagement is essential in the control of innate and adaptive immune responses. Inducible CD69 expression is strongly controlled at the transcriptional level. The molecular basis for developmental- and stage-specific regulation in T cells is beginning to be ...
Zurek Daniel B - - 2012
The modular visual system of jumping spiders (Salticidae) divides characteristics such as high spatial acuity and wide-field motion detection between different pairs of eyes. A large pair of telescope-like anterior-median (AM) eyes is supported by 2-3 pairs of 'secondary' eyes, which provide almost 360 degrees of visual coverage at lower ...
Wu Jueheng - - 2012
Identification of endogenous angiogenesis inhibitors has led to development of an increasingly attractive strategy for cancer therapy and other angiogenesis-driven diseases. Vascular endothelial growth inhibitor (VEGI), a potent and relatively nontoxic endogenous angiogenesis inhibitor, has been intensively studied, and this work shed new light on developing promising anti-angiogenic strategies. It ...
Hulten Edward A - - 2012
While multiple different imaging tests can be used to evaluate patients with known or suspected coronary artery disease (CAD), each of them is designed to evaluate either coronary anatomy or physiology. Recently, it has been recognized that cardiac CT can be used to evaluate stress and rest myocardial perfusion in ...
Huck C W - - 2012
The measurement of the physical and chemical ("physicochemical") properties of nanomaterials usedin industry and science including including chemistry, pharmacy, medicine, toxicology, etc., is time-consuming, expensive and requires a lot of experience of a well trained lab staff. Near-infrared spectroscopy (NIR; 4.000 - 12.000 cm-1), working in the wavelength region with ...
Lugenbiel Patrick - - 2012
Gene therapy-based modulation of atrioventricular (AV) conduction by overexpression of a constitutively active inhibitory Gα( i ) protein effectively reduced heart rates in atrial fibrillation (AF). However, catecholamine stimulation caused an excessive increase in ventricular rate. We hypothesized that modest genetic suppression of a stimulatory G protein in the AV ...
Burdick Jason A - - 2012
Hydrogels are water-swollen polymer networks that are being developed for a range of applications, from tissue engineering to drug delivery. The last decade has seen widespread advances in the design of novel hydrogel systems, enhancing their functionality and utility in biomedicine [1, 2]. Hydrogels exhibit high water content and can ...
Vanić Zeljka - - 2012
Objective: The aim of this study was to investigate various deformable liposomes for their potential application for the vaginal administration of metronidazole. Materials and methods: Deformable liposomes composed of egg phosphatidylcholine (EPC) and various surfactants [sodium deoxycholate (SDCh), Tween 80 or Span 80] and conventional liposomes consisting of EPC and ...
Yamaguchi-Kabata Yumi - - 2012
Although the Japanese population has a rather low genetic diversity, we recently confirmed the presence of two main clusters (the Hondo and Ryukyu clusters) through principal component analysis of genome-wide single-nucleotide polymorphism (SNP) genotypes. Understanding the genetic differences between the two main clusters requires further genome-wide analyses based on a ...
Cohen Philip N - - 2012
Gender differences in color preferences have been found in adults and children, but they remain unexplained. This study asks whether the gendered social environment in adulthood affects parents' color preferences. The analysis used the gender of children to represent one aspect of the gendered social environment. Because having male versus ...
Smichi Nabil - - 2012
Studies on the digestive secretions in aquatic animals can elucidate certain aspects of their nutritive physiology. The aim of the present study was to compare the digestive lipase and phospholipase activities in ten marine species belonging to four classes following the taxonomic classification of marine organisms. All aquatic digestive tissues ...
Singh Shweta - - 2012
Lafora progressive myoclonus epilepsy, also known as Lafora disease (LD), is the most severe and fatal form of progressive myoclonus epilepsy with its typical onset during the late childhood or early adolescence. LD is characterized by recurrent epileptic seizures and progressive decline in intellectual function. LD can be caused by ...
Wu Tong - - 2012
Organometallic rectangle which undergoes [2+2] cycloaddition upon irradiation with sunlight and organometallic prism which displayed interesting host-guest property were self-assembled based on a versatile building block.
Zhao Bijun - - 2012
Heat shock protein (HSP) 70 plays a critical role in protecting the heart from various stressor-induced cell injuries; the mechanism remains to be further understood. The present study aims to elucidate the effect of a probiotics-derived protein, LGG-derived protein p75 (LGP), in alleviating the ischemia/reperfusion (I/R)-induced heart injury. We treated ...
Zijlmans Mariken - - 2012
Abstract Background: Precise laparoscopic liver resection requires accurate planning and visualization of important anatomy such as vessels and tumors. Combining laparoscopic ultrasound with navigation technology could provide this. Preoperative images are valuable for planning and overview of the procedure, while intraoperative images provide an updated view of the surgical field. ...
Ogawa Tetsuya - - 2012
Vitamin D deficiency is common in hemodialysis (HD) patients. The aim of this study was to determine whether HD patients with low 25-hydroxyvitamin D [25(OH)D] levels are at increased risk of mortality. This was a prospective cohort study of Japanese HD patients. We selected all patients with measured serum 25(OH)D ...
Smith William B - - 2012
Clevidipine is a rapidly-acting intravenous dihydropyridine antihypertensive acting via calcium channel blockade. This was a randomized, single-blind, parallel-design study of a 72-h continuous clevidipine infusion. Doses of 2, 4, 8, or 16.0 mg/h or placebo were evaluated in 61 subjects with mild to moderate essential hypertension. IV clevidipine or placebo was ...
da Rocha Lapa Fernanda - - 2012
Adenosine and its metabolite, inosine, have been described as molecules that participate in regulation of inflammatory response. The aim of this study was to investigate the effect of adenosine and inosine in a mouse model of carrageenan-induced pleurisy as well as the participation of adenosine receptors in this response. Injection ...
Alford Chris - - 2012
This study investigated the coadministration of an energy drink with alcohol to study the effects on subjective intoxication and objective performance. This study aims to evaluate the objective and subjective effects of alcohol versus placebo at two alcohol doses, alone and in combination with an energy drink, in a balanced ...
Janowski Konrad - - 2012
Social support was shown to be an important factor buffering negative effects of stress in a range of clinical populations. Little is known, however, about the role of social support in the population of patients with psoriasis although strong psychosocial stress has been implicated in this disease. The objective of ...
Simar David - - 2012
Induction of heat shock proteins (Hsp) 72 and 27 can improve insulin signalling in obesity and type 2 diabetes via inhibition of key stress kinases. In metabolic disease, altered insulin signalling, as illustrated by increased serine phosphorylation of insulin receptor substrate (IRS)-1 (Ser312), is not confined to muscle or liver ...
Schito Marco - - 2012
Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis. Despite the need to strengthen existing laboratory infrastructure, which includes expanding and developing new laboratories, there are clear diagnostic needs where conventional laboratory support ...
Desai Esha S - - 2012
We recently showed that superporous hydrogel (SPH) scaffolds promote long-term stem cell viability and cell driven mineralization when cells were seeded within the pores of pre-fabricated SPH scaffolds. The possibility of cell encapsulation within the SPH matrix during its fabrication was further explored in this study. The impact of each ...
Srinivasan Padma P - - 2012
The goal of this study was to use bioengineered injectable microgels to enhance the action of bone morphogenetic protein 2 (BMP2) and stimulate cartilage matrix repair in a reversible animal model of osteoarthritis (OA). A module of perlecan (PlnD1) bearing heparan sulfate (HS) chains was covalently immobilized to hyaluronic acid ...
Erickson Isaac E - - 2012
Functional repair of focal cartilage defects requires filling the space with neotissue that has compressive properties comparable to native tissue and integration with adjacent host cartilage. While poor integration is a common complication with current clinical treatments, reports of tissue engineering advances in the development of functional compressive properties rarely ...
Bartlett Rebecca S - - 2012
Vocal folds are anatomically and biomechanically unique, thus complicating the design and implementation of tissue engineering strategies for repair and regeneration. Integration of an enhanced understanding of tissue biomechanics, wound healing dynamics and innovative gel-based therapeutics has generated enthusiasm for the notion that an efficacious treatment for vocal fold scarring ...
Young D A - - 2012
Adipose tissue engineering has recently gained significant attention from materials scientists as a result of the exponential growth of soft tissue filler procedures being performed within the clinic. While several injectable materials are currently being marketed for filling subcutaneous voids, they often face limited longevity due to rapid resorption. Their ...
Kim Min Jee - - 2012
To determine the prevalence of Y chromosome microdeletions in infertile Korean men with abnormal sperm counts and to assess the clinical features and frequency of chromosomal abnormalities in Korean patients with microdeletions. A total of 1,306 infertile men were screened for Y chromosome microdeletions, and 101 of them had microdeletions. ...
Kim Jessica S - - 2012
The accumulated mucin in non-Gottron's dermatomyositis (DM) lesions is primarily chondroitin-4-sulfate (C4S), which is immunomodulatory in vitro. Gottron's papules are a particularly resistant manifestation of DM that often persist after other lesions have resolved with therapy. We examined non-Gottron's DM lesions and Gottron's papule skin biopsies for C4S, CD44 variant ...
Dubrow Robert - - 2012
We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk. At baseline in 1995-1996, dietary intake, including coffee, tea, and soda, was ...
John R C - - 2012
Polycyclic aromatic hydrocarbon (PAH)-degrading bacteria were isolated from aviation fuel contaminated soil at Inua Eyet Ikot in Ibeno, Nigeria. PAH-degrading bacteria in the contaminated soil were isolated by enrichment culture technique. Isolates with high PAH degrading potential characterized by their extensive growth on PAH-supplemented minimal salt medium were screened for ...
Zuno-Floriano Fabiola G - - 2012
This study was conducted to evaluate the effect of molinate on retinoids homeostasis in rat testis. Molinate was administrated to male Sprague-Dawley rats (200 mg kg(-1) in corn oil, ip). Retinoid measurements were made at 6, 12, 48 and 168 h time points after administration. Testis levels of retinoic acid ...
Stegmann Kerstin A - - 2012
Natural killer (NK) cells are an important component of the innate immune defense against viruses, including hepatitis C virus (HCV). The cell culture system using HCV-permissive Huh-7.5 cells make studies on interaction of NK cells and HCV-infected target cells possible. We used this system to characterize interactions of HCV-infected Huh-7.5 ...
Gordon Rachel J - - 2012
Little is known about the clonality of Staphylococcus epidermidis in the United States, although it is the predominant pathogen in infections involving prosthetic materials, including ventricular assist devices (VADs). Seventy-five VAD recipients at 4 geographically diverse US cardiac centers were prospectively followed up to 1 year of VAD support. The ...
Clutterbuck Elizabeth A - - 2012
A 23-valent unconjugated pneumococcal polysaccharide vaccine (23vP), routinely administered at the age of 65, has limited effectiveness, and revaccination induces attenuated antibody responses. It is not known whether pneumococcal polysaccharide-protein conjugated vaccines (PCV), although highly effective in infants, offer any immunological advantages over 23vP in adults. We immunized adults with ...
Tekola Ayele Fasil - - 2012
Podoconiosis is a tropical lymphedema resulting from long-term barefoot exposure to red-clay soil derived from volcanic rock. The World Health Organization recently designated it as a neglected tropical disease. Podoconiosis develops in only a subgroup of exposed people, and studies have shown familial clustering with high heritability (63%). We conducted ...
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