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Kim Jessica S JS New York University School of Medicine, New York, New York, - - 2012
The accumulated mucin in non-Gottron's dermatomyositis (DM) lesions is primarily chondroitin-4-sulfate (C4S), which is immunomodulatory in vitro. Gottron's papules are a particularly resistant manifestation of DM that often persist after other lesions have resolved with therapy. We examined non-Gottron's DM lesions and Gottron's papule skin biopsies for C4S, CD44 variant ...
Huang Eric Yi-Hsiu - - 2012
PURPOSE: To review the perioperative and follow-up outcomes of patients undergoing radical cystectomy with orthotopic neobladder reconstruction for bladder cancer after prior radical prostatectomy (RP) for prostate cancer. METHODS: A retrospective review of more than 1,900 patients treated with radical cystectomy at USC between 1990 and 2011 was conducted. Fifty-six ...
Roa J J - - 2012
In the last years, Nanoindentation or Instrumented Indentation Technique has become a powerful tool to study the mechanical properties at micro/nanometric scale (commonly the hardness, Elastic modulus and the stress-strain curve). In this review, the different contact mechanisms (elastic and elasto-plastic)are discussed,the recent patentsfor each mechanism (elastic and elato-plastic)are summarized ...
Carlomagno Teresa - - 2012
Covering: up to 2011Natural products are of tremendous importance in both traditional and modern medicine. For medicinal chemistry natural products represent a challenge, as their chemical synthesis and modification are complex processes, which require many, often stereo-selective, synthetic steps. A prerequisite for the design of analogs of natural products, with ...
Zhao Jingjin - - 2012
A simple label-free fluorescent sensing scheme for sensitive and selective detection of nicotinamide adenine dinucleotide (NAD(+)) has been developed based on DNA ligation reaction with ligand-responsive quadruplex formation. This approach can detect 0.5 nM NAD(+) with high selectivity against other NAD(+) analogs.
Shin Seungwoo - - 2012
Aspirin-exacerbated respiratory disease (AERD) is associated with severe asthma and aspirin can cause asthma to worsen, often in the form of a severe and sudden attack. The oral aspirin challenge is the gold standard to confirm the diagnosis of AERD, but it is time consuming and produces serious complications in ...
Ozturk Necla - - 2012
Pressure applied during harvesting of the saphenous vein (SV) graft in coronary artery bypass surgery might change its mechanical properties and thereby decrease the patency. This study was performed to assess the mechanical properties of the SV graft distended manually with different levels of pressure and to determine the pressure ...
Ogawa Tetsuya - - 2012
Vitamin D deficiency is common in hemodialysis (HD) patients. The aim of this study was to determine whether HD patients with low 25-hydroxyvitamin D [25(OH)D] levels are at increased risk of mortality. This was a prospective cohort study of Japanese HD patients. We selected all patients with measured serum 25(OH)D ...
Messias André - - 2012
To evaluate changes in electroretinographic (ERG) findings after panretinal photocoagulation (PRP) compared to PRP plus intravitreal injection of ranibizumab (IVR) in eyes with high-risk proliferative diabetic retinopathy (PDR). Patients with high-risk PDR and no prior laser treatment were assigned randomly to receive PRP (PRP group; n = 9) or PRP plus IVR ...
Malik Shabnam - - 2012
Diethylnitrosamine (DEN), found in many commonly consumed foods, has been reported to induce cancers in animals and humans. Several models have been developed to study multistage carcinogenesis in rat liver; these include the Solt-Farber-resistant hepatocyte model. In the Solt-Farber model, the initiation consists of either a necrogenic dose of a ...
Narita Masato - - 2012
BACKGROUND: Portal triad clamping (PTC) has been widely adopted in an attempt to decrease bleeding during liver parenchymal transection. As a larger proportion of patients are treated with chemotherapy prior to liver resection, the safety of PTC in patients with chemotherapy-associated liver injury remains poorly investigated. This study aims to ...
Pangeni Gobinda - - 2012
The aim of this study is to measure the on- and off-responses and their response asymmetries elicited by sawtooth stimuli in normal subjects and glaucoma patients. Furthermore, the correlation between the ERGs and other functional and structural parameters are investigated. Full-field stimuli were produced using a Ganzfeld bowl with Light ...
Rousseau-Harrison Kate - - 2012
Purpose: Mobility aids not only compensate for a locomotor disability, they also increase users' opportunities for social participation. The objective was to explore the impacts of wheelchair (WC) acquisition on children's social participation, personal factors and social environment.Methods: A literature review was done in MEDLINE for the years 1996 to ...
Leung Galen G - - 2012
INTRODUCTION: Patients with inflammatory bowel disease, such as Crohn's disease (CD), suffer from a threefold increase in the risk of venous thromboembolism. Small bowel, segmental bowel, or ileocolonic resection to treat Crohn's disease can lead to rare complications of portal vein thrombosis (PVT), which can lead to further poor health ...
Kumar Arvind - - 2012
About a quarter of angiosperm species are stipulate. They produce stipule pairs at stem nodes in association with leaves. Stipule morphology is treated as a species-specific characteristic. Many species bear stipules as laminated organs in a variety of configurations, including laterally free large foliaceous, small, or wholly leaf-like stipules, and ...
Chiang Huei-Hsin - - 2012
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative syndrome primarily affecting the upper and lower motor neurons. A characteristic neuropathological finding in ALS patients is neuronal inclusions positive for TAR DNA-binding protein 43 (TDP-43). Subsequently, mutations in the gene encoding TDP-43, TARDBP, proved to be involved in the development of ALS. ...
Oesch Franz - - 2012
This review is based on the lecture presented at the April 2010 nanomaterials safety assessment Postsatellite to the 2009 EUROTOX Meeting and summarizes genotoxicity investigations on nanomaterials published in the open scientific literature (up to 2008). Special attention is paid to the relationship between particle size and positive versus negative ...
Mazeh Haggi - - 2012
BACKGROUND: Current recommendations for treating acute calculus cholecystitis include the use of intravenous antibiotics, although these recommendations were never tested scientifically. The aim of this study was to evaluate the role of intravenous antibiotic therapy in patients with mild acute calculus cholecystitis. METHODS: In this prospective, randomized controlled trial, 84 ...
Steidl P - - 2012
Irradiation of moving targets using a scanned ion beam can cause clinically intolerable under- and overdosages within the target volume due to the interplay effect. Several motion mitigation techniques such as gating, beam tracking and rescanning are currently investigated to overcome this restriction. To enable detailed experimental studies of potential ...
Thakur P P Carlsbad Environmental Monitoring & Research Center, 1400 University Drive, Carlsbad, New Mexico-88220, USA. - - 2012
The release of radioactivity into the atmosphere from the damaged Fukushima Daiichi nuclear power plant started on March 12th, 2011. Among the various radionuclides released, iodine -131 ((131)I) and cesium isotopes ((137)Cs and (134)Cs) were transported across the Pacific Ocean and reached the United States on 17-18 March 2011. Consequently, ...
Dubrow Robert R Yale School of Public Health, Yale School of Medicine, New Haven, CT, USA. - - 2012
We utilized the large, prospective NIH-AARP Diet and Health Study to further explore the hypothesis, suggested by two recent prospective cohort studies, that increased intake of coffee, tea, soda, and/or caffeine is associated with reduced adult glioma risk. At baseline in 1995-1996, dietary intake, including coffee, tea, and soda, was ...
Deguchi Jun - - 2012
We prepared a series of acerogenins A and B derivatives as inhibitors of nitric oxide (NO) production in vitro. Our results suggested that an ester group at a hydroxyl at C-2 improved inhibitory effects without cytotoxicity. A benzoyl ester derivative of acerogenin C showed the most potent inhibitory activity of ...
Bertanha Camila S - - 2012
Chemical investigation of the n-hexane and EtOAc fractions of the ethanolic extract from Styrax pohlii (Styracaceae) aerial parts resulted in the isolation of the benzofuran nor-neolignan derivatives egonol (1), homoegonol (2), homoegonol gentiobioside (3), homoegonol glucoside (4) and egonol gentiobioside (5). This is the first report of compounds 1-5 in ...
Lin Genyao - - 2012
Here we report the design and characterization of injectable and thermosensitive hydrogel composites comprised of poly(lactic acid-co-glycolic acid)-g-poly(ethylene glycol)(PLGA-g-PEG) containing hydroxyapatite (HA) for potential application in bone tissue engineering. Inclusion of HA into the hydrogels would provide both enhanced mechanical properties and bioactivity to the composites. The effects of HA ...
Ding Yue - - 2012
The safety of geniposide, mainly focusing on its hepatotoxicity in rats, was determined by liver enzymes in serum and histopathology ultrastructural preparation. The lethal dose, 50% (LD(50)) of per oral geniposide was 1431.1 mg kg(-1). The acute toxicity study indicated geniposide at dose of 574 mg kg(-1) or more could cause hepatic toxicity in ...
Sulaiman Yusran - - 2012
Chiral conducting polymers prepared by electropolymerising PEDOT in the presence of chiral anions such as hyaluronic acid and anionic collagen or in a chiral nematic phase (hydroxypropyl cellulose, HPC) show excellent chiral acid recognition. This paper demonstrates the enantioselective recognition and transfer of protonated mandelic acid and protons using chiral ...
Welner Ditte H - - 2012
NAC (NAM/ATAF/CUC) plant transcription factors regulate essential processes in development, stress responses and nutrient distribution in important crop and model plants (rice, Populus, Arabidopsis), which makes them highly relevant in the context of crop optimization and bioenergy production. The structure of the DNA-binding NAC domain of ANAC019 has previously been ...
Stegen James C - - 2012
A major goal of microbial community ecology is to understand the forces that structure community composition. Deterministic selection by specific environmental factors is sometimes important, but in other cases stochastic or ecologically neutral processes dominate. Lacking is a unified conceptual framework aiming to understand why deterministic processes dominate in some ...
Marrelli Mariangela - - 2012
Colon cancer is one of the major causes of cancer mortality worldwide. The analysed feeds, containing non-genetically modified (GM) soybean and Roundup Ready soybean, showed a different polyphenolic content and lipophilic composition. Non-GM soybean extract possessed twice the polyphenolic content of GM soybean and the highest number of sterols. Among ...
Seman Milan - - 2012
The occurrence of Vibrio cholerae, an important aquatic pathogen, was assessed in the surface water of the Danube River near Bratislava. The isolates were distinguished by biochemical tests and grouped by ARDRA to three clusters corresponding to three species (V. cholerae, Vibrio metschnikovii, and Aeromonas spp.). The identification of V. ...
Farook Vidya S VS Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA. - - 2012
The prevalence of metabolic syndrome (MS) has been rising alarmingly worldwide, including in the United States, but knowledge on specific genetic determinants of MS is very limited. Therefore, we planned to identify the genetic determinants of MS as defined by National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATPIII) criteria. We ...
Zhao Bijun - - 2012
Heat shock protein (HSP) 70 plays a critical role in protecting the heart from various stressor-induced cell injuries; the mechanism remains to be further understood. The present study aims to elucidate the effect of a probiotics-derived protein, LGG-derived protein p75 (LGP), in alleviating the ischemia/reperfusion (I/R)-induced heart injury. We treated ...
Zijlmans Mariken - - 2012
Abstract Background: Precise laparoscopic liver resection requires accurate planning and visualization of important anatomy such as vessels and tumors. Combining laparoscopic ultrasound with navigation technology could provide this. Preoperative images are valuable for planning and overview of the procedure, while intraoperative images provide an updated view of the surgical field. ...
Basu Saumyajit - - 2012
The purpose of the study was to find out if transpedicular decancellation osteotomy (TDO) is recommendable for neurological recovery in patients with myelopathy due to tubercular rigid kyphosis. We have analyzed the pattern of recovery seen after the surgery and also made an effort to correlate the neurological recovery with ...
Simar David - - 2012
Induction of heat shock proteins (Hsp) 72 and 27 can improve insulin signalling in obesity and type 2 diabetes via inhibition of key stress kinases. In metabolic disease, altered insulin signalling, as illustrated by increased serine phosphorylation of insulin receptor substrate (IRS)-1 (Ser312), is not confined to muscle or liver ...
Zang Yongyuan - - 2012
Electrical and thermal properties of a carbon nanotube (CNT)/multiferroic BiFeO(3) (BFO)/Pt photovoltaic heterojunction are investigated for the first time. Enhanced photovoltaic properties (J(sc) ≈ 2.1 μA cm(-2) and V(oc) ≈ 0.47 V), as compared to the traditional polycrystalline BFO with indium tin oxide (ITO) as the top electrode, are observed ...
Chung E - - 2012
PURPOSE: To evaluate the clinical outcomes of penile prosthesis implantation for the treatment for erectile dysfunction (ED) over 3 decades in a centre of excellence. METHODS: A total of 955 penile prostheses were implanted between June 1981 and June 2010. The mean age of the men was 53.2 (28-80) years, ...
Maruthavanan T - - 2012
A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7-12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7-12) were assayed for antibacterial, antifungal and anthelmintic activities and they exhibited significant results.
Hawkins Summer Sherburne - - 2012
To examine the impact of cigarette excise taxes and smoke-free legislation on tobacco use among households with school-age children and adolescents as well as disparities in children's secondhand smoke exposure. We compare the results from models using causal inference techniques to those from cross-sectional models. We linked families of 6-17-year-olds ...
Hellmuth Marc - - 2012
Orthology detection is an important problem in comparative and evolutionary genomics and, consequently, a variety of orthology detection methods have been devised in recent years. Although many of these methods are dependent on generating gene and/or species trees, it has been shown that orthology can be estimated at acceptable levels ...
Kwitko Sérgio - - 2012
BACKGROUND: Precise IOL calculation in post-refractive surgery patients is still a challenge for the cataract surgeon. The purpose of this study is to test whether adding Orbscan II values into the double-K method improves IOL calculation in this group of patients. METHODS: A prospective study with 43 eyes previously submitted ...
Wiser Amir - - 2012
Objective: To evaluate if monitoring patients by ultrasound (US) only during in vitro fertilization (IVF) treatment is safe. Design: Randomized prospective study. Intervention: Patients undergoing their first IVF treatment were randomized into two groups. The ultrasound only group (study group) was monitored by US for follicle size and endometrial thickness ...
Hauglann Beate - - 2012
PURPOSE: The aims of this cohort study were to explore various longitudinal aspects of employment and disability pension due to permanently reduced work ability among women with breast cancer and to investigate the impact of breast cancer on income. PATIENTS AND METHODS: In a national register-based controlled cohort study from ...
Bangert Mathieu - - 2012
New treatments against severe bacterial infections are needed because the response to antibiotic treatment is slow in acute settings and is becoming less effective owing to the emergence of antibiotic-resistant pathogens. P4-mediated antibody therapy offers a unique treatment strategy that combines exogenous immunoglobulin with the immunoactivating peptide P4. In an ...
Zhu Xiaoqing - - 2012
In matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS), the analysis capability, especially for small molecules, is often compromised by the addition of organic matrices due to the existence of background signals. Herein we report a new detection method on the utility of core-shell nanoparticles (CSNPs) as energy transfer ...
Ding Dongfeng - - 2012
In eukaryotes, the spindle assembly checkpoint (SAC) ensures the fidelity of chromosome segregation through monitoring the bipolar attachment of microtubules to kinetochores. Recently, the SAC components Mitotic Arrest Deficient 1 and 2 (MAD1 and MAD2) were found to associate with the nuclear pore complex (NPC) during interphase and to require ...
Cristina Tote Franco Pinotti Solange - - 2012
Objective: To study the prevalence of breast cysts in several age groups of the general female population and their association with the MspAI polymorphism of the gene CYP17. Results: In 204 ultrasound tests, cysts were present in 22% of the studied population. The epidemiological-clinical profile of these women was Caucasian, ...
Lee Han-Hyoung - - 2012
Since T cells express diverse sex steroid hormone receptors, they might be a good model to evaluate the effects of sex steroid hormones on immune modulation. Porcine testicular extract contains several sex steroid hormones and may be useful to study the effects of sex steroid hormones during T cell activation. ...
Basavaiah N - - 2012
BACKGROUND, AIM, AND SCOPE: Soils of basaltic origin cause difficulties in environmental magnetic screening for heavy metal pollution due to their natural high background values. Magnetic parameters and heavy metal content of highly magnetic topsoils from the Deccan Trap basalts are investigated to assess their potential for use in environmental ...
Okassa M - - 2012
Several species of the family Phytoseiidae are known to control mite pests in many crops worldwide. However, biological control success greatly depends on the accurate identification of these predatory mites. Species diagnostics is essentially based on the morphological characters of females. Thus, when only immature stages and/or males are collected, ...
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