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Hestad Knut A KA Department of Psychology, The Norwegian University of Science and Technology, Trondheim, Norway. - - 2012
This study examined whether there are neuropsychological performance differences between human immunodeficiency virus-seropositive participants being followed at a University of Zambia clinic and demographically comparable seronegative controls being tested for infection in the same setting. All participants were administered a standardized neurocognitive test battery that has been found sensitive to ...
Ichiki M M Department of Radiology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan. - - 2012
The purpose of this study was to evaluate the MRI characteristics of venous thrombus over set time thresholds with histopathological correlation in a porcine model. Inferior vena cava thrombi were induced in 12 pigs. MRI was performed in three pigs 2 h, 1 day, 3 days and 2 weeks after ...
Journy N N Institut de Veille Sanitaire, Saint-Maurice, France. - - 2012
The study aimed to characterise the factors related to the X-ray dose delivered to the patient's skin during interventional cardiology procedures. We studied 177 coronary angiographies (CAs) and/or percutaneous transluminal coronary angioplasties (PTCAs) carried out in a French clinic on the same radiography table. The clinical and therapeutic characteristics, and ...
Young Annie A Roche Products Ltd, Welwyn Garden City, - - 2012
Dalcetrapib, a cholesteryl ester transfer protein modulator, under development to increase high-density lipoprotein cholesterol and potentially decrease cardiovascular risk, will potentially be co-prescribed to women on oral contraceptive (OC). Assess the effect of dalcetrapib on the pharmacokinetics and ability to suppress ovulation of Microgynon® 30, a representative monophasic OC. A ...
Voshaar Thomas T Krankenhaus Bethanien, Moers, IMS Health, Frankfurt, - - 2012
Asthma is one of the most common chronic diseases worldwide. Patient persistence with treatment is essential to achieve sufficient outcomes, in particular to avoid exacerbations. To investigate inhaled corticosteroid (ICS) therapy with two different inhalers (Novolizer® and Turbuhaler®) by comparing persistence, concomitant use of additional asthma medication and occurrence of ...
Lin Kant Y KY Department of Plastic Surgery, University of Virginia Health System, Box 800376, Charlottesville, VA 22908, USA. - - 2012
More women with breast cancer who either have already had radiation therapy or will be getting radiation therapy as part of their treatment protocol are now seeking implant-based breast reconstruction. The literature on the success of this type of reconstruction in the setting of radiation injury is mixed. A single ...
Aschen Seth S Divisions of Plastic and Reconstructive Surgery and Breast Surgery, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, - - 2012
Although fat deposition is a defining clinical characteristic of lymphedema, the cellular mechanisms that regulate this response remain unknown. The goal of this study was to determine how lymphatic fluid stasis regulates adipogenic gene activation and fat deposition. Adult female mice underwent tail lymphatic ablation and were euthanied at 1, ...
Li Weiwei W Department of Orthopaedic Surgery and the Developmental Division of Advanced Orthopaedic Therapeutics, Graduate School, Tokyo Medical and Dental University, Tokyo, - - 2012
Flap necrosis remains a major complication of reconstructive surgery. To improve skin flap survival, various treatments with vasodilators, antiplatelet drugs, or the local administration of growth factors have been performed. However, the sufficient prevention of skin necrosis is not well established. Platelet-rich plasma has been used as an autologous factor ...
Sucher Robert R Research Laboratory Innsbruck Medical University Anichstrasse 35 A-6020 Innsbruck, Austria. - - 2012
Rat models of experimental face transplantation have been widely used to study vascularized composite tissue allotransplantation. Because the mouse represents a superior species for vascularized composite tissue allotransplantation research, the authors developed a novel surgical technique with which to perform hemiface transplantation in mice. BALB/c hemifacial grafts were transplanted into ...
Ono Shimpei S Department of Plastic, Reconstructive, and Aesthetic Surgery, Nippon Medical School, 1-1-5 Sendagi Bunkyo-ku, Tokyo 113-8603, Japan. - - 2012
The occipitocervicopectoral flap has a local skin pedicle in the occipital region, with the distal portion of the flap in the pectoral region. One disadvantage of the occipitocervicopectoral flap is its limited flap length. To overcome this disadvantage, a perforator supercharging technique was applied to enlarge the original flap length. ...
Campbell Kristin Turza KT Department of Plastic Surgery, Unit 1488, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, - - 2012
Human acellular dermal matrix is used for ventral hernia repair, as it resists infection and remodels by means of surrounding tissue. However, the tissue source and impact of basement membrane on cell and vessel infiltration have not been determined. The authors hypothesized that musculofascia would be the primary tissue source ...
Frost Christopher M CM Section of Plastic Surgery, University of Michigan, 2023 BSRB 109 Zina Pitcher Place, Ann Arbor, Mich. 48109-2200, - - 2012
The goal of the authors is to restore fine motor control and sensation for high-arm amputees. They developed a regenerative peripheral nerve interface with the aim of attaining closed loop neural control by integrating directly with the amputee's residual motor and sensory peripheral nerves. PEDOT, poly(3,4-ethylenedioxythiophene), has both electrical and ...
Lakin Gregory E GE Section of Plastic and Reconstructive Surgery, Department of Surgery, University of Michigan Health Systems, Ann Arbor, MI 48109, - - 2012
The pathoetiology of craniosynostosis is not well understood. It likely results from a combination of genetic and epigenetic phenomena, such as intrauterine constraint from multiple gestations. Information on craniosynostosis in twins is limited to case reports and series. The authors conducted a systematic review and meta-analysis of the literature to ...
Lazzeri Davide D Plastic and Reconstructive Surgery Unit, Hospital of Pisa Via Paradisa 2 Cisanello, 56100 Pisa, Italy. - - 2012
Complications following facial cosmetic injections have recently heightened awareness of the possibility of iatrogenic blindness. The authors conducted a systematic review of the available literature to provide the best evidence for the prevention and treatment of this serious eye injury. The authors included in the study only the cases in ...
Luce Edward A EA Department of Plastic Surgery, University of Tennessee, Memphis, TN, USA. - - 2012
The roots of the working hours mandate and controversy are outlined, the effect on resident education is described, and the service versus education equation is defined.
Taylor Kim O KO ARC Plastic Surgery and the Hematology Service, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia. - - 2012
There has never been a convincing association between breast implants and breast malignancy. A total of 42 cases of non-Hodgkin's lymphoma of the breast associated with implant capsules have been reported. The majority of the patients have anaplastic large cell lymphoma of T-cell origin. These lymphoma types have less frequently ...
Losken Albert A Emory Division of Plastic Surgery 550 Peachtree Street, Suite 84300 Atlanta, GA 30308, USA. - - 2012
There is an ongoing debate about the reliability of various lower abdominal flaps for breast reconstruction. The authors evaluate in vivo perfusion of these flaps to objectively determine which techniques and which skin island zones had better perfusion. A prospective study was performed on 77 single-pedicle breast reconstructions [pedicled transverse ...
O╩╝donovan David A DA Division of Plastic Surgery, The Hospital for Sick Children Center for Craniofacial Care and Research, The Hospital for Sick Children Research Institute, University of Toronto, Toronto, Ontario, - - 2012
The authors previously established an animal model of radiation-induced craniofacial bone growth inhibition and demonstrated the effectiveness of cytoprotection in preserving growth using amifostine, but the mechanism is unclear. The objective of this study was to investigate the acute and long-term histopathologic effects of single-dose orthovoltage irradiation on craniofacial bone ...
Tchanque-Fossuo Catherine N CN University of Michigan Medical School, the University of Michigan, MI 48109-5340, - - 2012
Radiotherapy, a cornerstone of head and neck cancer treatment, causes substantial morbidity to normal adjoining bone. The authors assessed the radioprotective effect of amifostine therapy on the mineralization of the mandible using micro-computed tomography. They hypothesized that amifostine would safeguard the mandible from radiation-induced disruption of the mineralization process and ...
Chepla Kyle J KJ Department of Plastic and Reconstructive Surgery, University Hospitals Case Medical Center, Case Western Reserve School of Medicine 29017 Cedar Road, Cleveland, Ohio 44124, - - 2012
Although 92 percent of patients who undergo surgical decompression of the supraorbital nerve for treatment of frontal migraine headaches through resection of the glabellar muscle group achieve at least 50 percent improvement, only two-thirds demonstrate complete resolution of symptoms. The authors investigated the role of additional decompression methods by comparing ...
Taylor Jesse A JA Department of Surgery, The Children’s Hospital of Philadelphia The University of Pennsylvania Colket Translational Research Building, 9th Floor Philadelphia, PA. 19104, USA. - - 2012
The treatment of multisuture syndromic craniosynostosis is in evolution, with an increasing prevalence of reports on posterior vault expansion with distraction osteogenesis over conventional osteotomy. The purported benefits of distraction osteogenesis include less perioperative morbidity. The authors conducted this preliminary study to compare the perioperative course in children undergoing posterior ...
Schiller Jeffrey D - - 2012
The techniques of lower blepharoplasty are evolving to reflect the concept that the lower eyelid contour does not stop at the inferior orbital rim, and that the lid-cheek junction must often be modified to restore the midface to a youthful configuration. Multiple procedures have been proposed to smooth the lid-cheek ...
Thorne Charles H CH Department of Plastic Surgery, New York University School of Medicine 812 Park Avenue, New York, NY 10021-2759, USA. - - 2012
After reviewing this article, the participant should be able to: 1. Evaluate patient's ears for needed adjustments to size, shape, prominence, and symmetry. 2. Identify common ear deformities and describe methods to repair them. 3. Avoid or manage common complications associated with otoplasty and ear reconstruction. The essentials of otoplasty ...
Sbitany Hani H University of Pennsylvania Health System 10 Penn Tower 3400 Spruce Street, Philadelphia, PA 19104, USA. - - 2012
Despite common superficial venous system dominance of the abdominal wall, the majority of transverse rectus abdominis musculocutaneous (TRAM)/deep inferior epigastric perforator (DIEP) flaps drain adequately, due to communicating veins with the deep system. In cases where such connections are inadequate, it is necessary for the surgeon to correctly recognize resultant ...
Zampell Jamie C JC Divisions of Plastic and Reconstructive Surgery and Breast Surgery, Department of Surgery, Memorial Sloan-Kettering Cancer - - 2012
Although fat deposition is a defining clinical characteristic of lymphedema, the cellular mechanisms that regulate this response remain unknown. The goals of this two-part study were to determine the effect of lymphatic fluid stasis on adipogenesis and inflammation (part I) and how these changes regulate the temporal and spatial expression ...
Donneys Alexis A Plastic Surgery Section, University of Michigan Craniofacial Research Laboratory, Ann Arbor, MI 48109-4215, - - 2012
Bone regeneration during distraction osteogenesis is intricately associated with an enhanced vascular response. Augmenting this response may offer considerable clinical advantages such as optimizing the quality of regenerate formation, decreasing lengthy consolidation periods, or increasing regenerate size and distance. Using deferoxamine, an angiogenic transcriptional activator, the authors posit that substantial ...
Dellon A Lee AL Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, Johns Hopkins Hospital Outpatient Center, 8th Floor, McElderry 8161, 601 North Caroline Street, Baltimore, MD. 21287, - - 2012
The sympathetic innervation of the hand was demonstrated using formaldehyde staining techniques in the 1990s and provides a basis for both medical (botulinum toxin type A) and surgical (sympathectomy) therapeutic approaches. This research investigates the sympathetic innervation of the human foot using tyrosine hydroxylase immunohistochemistry. With institutional review board approval, ...
Jackson Oksana A OA Division of Plastic Surgery, 9th Floor Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia, PA 19104, - - 2012
The separation of conjoined twins presents a unique challenge to many pediatric surgical specialties. A multidisciplinary approach is essential for successful twin separation, and plastic surgeons are critical members of this surgical team when soft-tissue requirements preclude simple closure. In this article, the authors review multiple techniques available to plastic ...
Swanson Eric E - - 2012
Evaluation of changes in breast shape, particularly "upper pole fullness," "breast projection," and "bottoming out," has been made difficult by the lack of an accepted definition of these entities and no standardized system for measurements and comparison. Three-dimensional imaging is impractical for most surgeons and limited in providing evidence-based assessments. ...
Kung Theodore A TA Department of Surgery, Section of Plastic and Reconstructive Surgery, University of Michigan Health Systems, MI 48109, - - 2012
Contracture of the antecubital fossa is a common occurrence following thermal burn injury to the upper extremity. Scarring of the superficial tissues can be treated with a variety of surgical methods to provide release and coverage. However, complex scarring of the elbow, which involves the deeper structures, requires a patient-specific ...
Nagy Michael W MW Plastic Surgery of the Face and Body 1967 Highway 34 Suite 102 Wall, NJ 07719, USA. - - 2012
No scientific comparative study has demonstrated any statistically significant clinical improvement attributable to a new lipoplasty technology relative to traditional suction-assisted lipoplasty. This prospective study used a contralateral study design to evaluate postoperative differences between vibration amplification of sound energy at resonance (VASER)-assisted lipoplasty and suction-assisted lipoplasty. Twenty female patients ...
Luce Edward A EA Department of Plastic Surgery, University of Tennessee, Memphis, TN, - - 2012
Efforts to limit resident work hours are conceptually flawed. A fundamental solution to resident service requires funding, which currently is not feasible. An equally fundamental structuring of the system of surgical resident education is feasible and should be attained.
Li Ping - - 2012
Chronic kidney disease (CKD) and chronic liver disease are both very harmful to human health almost all over the world, which lead to the fibrosis of the two organs ultimately. Currently, there are few satisfactory therapeutic methods in treating the two diseases. Some research works from Chinese medicine and Western ...
- - 2012
Increasing the price of cigarettes reduces the demand for cigarettes, thereby reducing youth smoking initiation and cigarette consumption and decreasing the prevalence of cigarette use in the United States overall, particularly among youths and young adults. The most common way governments have increased the price of cigarettes is by increasing ...
- - 2012
In March and April 2011, the Hillsborough County Health Department (HCHD) Epidemiology Department (Tampa, Florida) investigated three clusters of rash illness linked to the white-marked tussock moth caterpillar among persons at two child care centers and one elementary school. At least 23 children and one adult were affected; most had ...
- - 2012
Autism spectrum disorders (ASDs) are a group of developmental disabilities characterized by impairments in social interaction and communication and by restricted, repetitive, and stereotyped patterns of behavior. Symptoms typically are apparent before age 3 years. The complex nature of these disorders, coupled with a lack of biologic markers for diagnosis ...
Braun S A - - 2012
The occurrence of multiple cutaneous leiomyomas can be indicative of hereditary cutaneous leiomyomatosis. This autosomal dominant disorder is due to germline mutations in the fumarate hydratase (FH) gene. Associations with uterine myomas and renal cell carcinomas have been described and are referred to as Multiple Cutaneous and Uterine Leiomyomas (MCUL) ...
Zhao Ying - - 2012
To explore the molecular mechanism of puerarin (Pue) in improving insulin resistance through observing its effect on the insulin resistance of 3T3-Li lipocyte induced by free fatty acid (FFA). 3T3-L1 preadipocyte was induced by a culture solution containing insulin, isobutyo-menthyl-xanthine, and dexamethasone to mature lipocyte, and it was divided into ...
Yin Lan - - 2012
To study the effect of Vaccinium uliginosum L., (VU) on the electroretinogram (ERG) and retinal pathological changes in rabbits after light-induced damage. Twenty-eight Chinchilla rabbits were randomly divided into four groups: administration beforehand (A), administration after injury (B), light injury without administration (C), and blank (D) groups. After a 4-week ...
Wang Guqi - - 2012
Contemporary Western medicines approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic hepatitis B (CHB), although available in China, have high costs, or major side effects and limited effectiveness. Research efforts have focused on looking for natural products as alternative medicines with low cost and ...
Zhang Ming-Yu - - 2012
To assess the effect of puerarin, a natural flavonoid found in Chinese Pueraria Lobata (Wild.) Ohwi, on promotion of new bone formation. Osteoblasts isolated from calvarial of newborn rats were cultured in vitro in the presence of puerarin at various concentrations. The viability of osteoblasts and alkaline phosphotase activity and ...
Gong Yuewen - - 2012
Liver fibrosis and hepatocellular carcinoma (HCC) are emerging health problems worldwide. Number of death due to HCC was steadily increased during the last decade. Although liver fibrosis and HCC have been investigated extensively, there are no successful and/or satisfactory therapies especially for patients with HCC. From our understanding of both ...
Dorenkamp M - - 2012
A 73-year-old man with nonischemic cardiomyopathy underwent catheter ablation of ventricular tachycardia that had resulted in frequent shocks from his implanted cardiac resynchronization therapy defibrillator (CRT-D). Coexisting atrial fibrillation required AV node ablation which rendered the patient pacemaker dependent. During follow-up, recurrent episodes of dizziness occurred caused by inhibition of ...
Yang Ping - - 2012
Our aim was to evaluate the safety and effectiveness of extracorporeal cardiac shock wave therapy (CSWT) for the patients with coronary heart disease (CHD) using a randomized, double-blind, controlled clinical trial design. Twenty-five patients with CHD were enrolled in this study. Fourteen of the patients were randomized into the CSWT ...
Zhang Ding - - 2012
An experiment was conducted to invest effects of chronic cadmium poisoning on Zn, Cu, Fe, Ca, and metallothionein gene expression and protein synthesis in liver and kidney in rats. Forty rats, 6 weeks old, were randomly allocated into two groups. A group was given CdCl(2) (1 mg/KgCd(2+)) by intraperitoneal injection once a ...
Motiwala Shweta R - - 2012
Vitamin D deficiency is a common condition that has well-documented effects on musculoskeletal health. A growing body of literature has related vitamin D deficiency to other chronic disorders, including cardiovascular disease. Several plausible biological mechanisms have been postulated to explain this association, including the effect of poor vitamin D status ...
Pang Wei - - 2012
To investigate the effect of puerarin on interleukin (IL)-8 mRNA expression and the protein release in the co-culture of human bronchial epithelial (BEAS-2B) cells and human neutrophils. BEAS-2B cells and neutrophills were cultured separately and co-cultured with puerarin (50, 100, and 200 μg/mL) for a predetermined time. Cytokines in culture ...
Deng Bo - - 2012
To study and evaluate the effect of Sangu Decoction (SGD, ) on the bone destruction due to mammary cancer metastasis. Metastasis rat mammary tumor-1 cells were transplanted into the left hind limb tibia of SD rats to establish the bone metastasis of the mammary cancer model. The modeled rats were ...
Girard Simon L - - 2012
Schizophrenia is a major mental disorder characterized by a deep disruption of the thinking process and of emotional response. For many decades, genetics studies have yielded little success in identifying genetic factors responsible for the disease. However, with the recent breakthroughs in genome analysis technologies, the field of the genetics ...
Yang Shu-Yu - - 2012
To investigate the therapeutic effects of Ping-tang Recipe (, PTR) on high-fat diet (HFD)-induced insulin resistance and non-alcoholic fatty liver disease (NAFLD), and to elucidate the underlying mechanisms. Forty male SD rats were included in the study. Ten rats were fed on normal diet as normal control, and thirty rats ...
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