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Scuffham J W - - 2012
An 80-year-old male with recurrent thyroid cancer and a percutaneous endoscopic gastrostomy (PEG) tube in situ was referred for radioiodine therapy and was administered 5510 MBq I-131 sodium iodide intravenously. Sequential whole-body images taken over the subsequent 7 days for dosimetric evaluation revealed an area of persistent high uptake in ...
Li Bin - - 2012
Porcine circovirus type 2 (PCV2) is the etiologic agent of porcine circovirus-associated disease. Here, we first report the complete genome sequence of PCV2 strain JSTZ, which was isolated from piglet stool samples and is highly prevalent in China. It will help in understanding the epidemiology and molecular characteristics of PCV2.
Donneys Alexis A Plastic Surgery Section, University of Michigan Craniofacial Research Laboratory, Ann Arbor, MI 48109-4215, - - 2012
Bone regeneration during distraction osteogenesis is intricately associated with an enhanced vascular response. Augmenting this response may offer considerable clinical advantages such as optimizing the quality of regenerate formation, decreasing lengthy consolidation periods, or increasing regenerate size and distance. Using deferoxamine, an angiogenic transcriptional activator, the authors posit that substantial ...
Punyawudho Baralee - - 2012
Mycophenolic acid (MPA) has become the first-line drug therapy for proliferative lupus nephritis, a common and serious complication of systemic lupus erythematosus. Although a sufficient MPA exposure is required, a high interindividual variability in the pharmacokinetics of MPA has been observed. The knowledge of MPA pharmacokinetics in lupus nephritis patients ...
Torsello G F - - 2012
The aim of the present article is to describe a new thoracic stent graft (Zenith TX2 Low-Profile TAA Endovascular Graft). Feasibility of endovascular repair of thoracic aortic aneurysms depends on several anatomic factors. A primary limitation is an adequate arterial approach. Since most currently used endografts require large introducer sheaths, ...
Katsanos K - - 2012
Modern critical limb ischemia management algorithms endorse an "endovascular first" strategy of treatment. The advent of stents coated with anti-restenotic agents that are gradually eluted to the vessel wall has revolutionized modern endovascular therapies. Several single-center, non-randomized cohort series have provided compelling data about the short- to mid-term safety and ...
Lysaker Paul H - - 2012
ABSTRACT: Although negative symptoms are a barrier to recovery from schizophrenia, little is understood about the psychological processes that reinforce and sustain them. To explore this issue, this study used structural equation modeling to test whether the impact of social withdrawal and emotion recognition deficits upon negative symptoms is mediated ...
Frost Christopher M CM Section of Plastic Surgery, University of Michigan, 2023 BSRB 109 Zina Pitcher Place, Ann Arbor, Mich. 48109-2200, - - 2012
The goal of the authors is to restore fine motor control and sensation for high-arm amputees. They developed a regenerative peripheral nerve interface with the aim of attaining closed loop neural control by integrating directly with the amputee's residual motor and sensory peripheral nerves. PEDOT, poly(3,4-ethylenedioxythiophene), has both electrical and ...
Banner Bill - - 2012
Systemic lead poisoning may occur from ingested lead foreign bodies. Rarely, these may cause a retained appendolith. The risks of lead toxicity from these appendoliths, the time course of retention in the appendix, the rapidity of inhibition of heme synthesis, and the best approach to removal remain controversial. Fourteen days ...
Morrissey N J - - 2012
Distal embolization (DE) during lower extremity arterial intervention is a potentially devastating complication which could lead to limb loss. The use of a distal embolic protection device (EP) may prevent significant DE during intervention. Studies investigating the incidence and impact of DE suggest that it is a rare event with ...
Maan Narender S - - 2012
We report the full-genome sequence of an Indian isolate of bluetongue virus serotype 1 (BTV-1), strain IND1992/01. This is the first report of the entire genome sequence (Seg-1 to Seg-10) of an Eastern (e) strain of BTV-1. These sequence data provide a reference for BTV-1e that will help to define ...
Li Weiwei W Department of Orthopaedic Surgery and the Developmental Division of Advanced Orthopaedic Therapeutics, Graduate School, Tokyo Medical and Dental University, Tokyo, - - 2012
Flap necrosis remains a major complication of reconstructive surgery. To improve skin flap survival, various treatments with vasodilators, antiplatelet drugs, or the local administration of growth factors have been performed. However, the sufficient prevention of skin necrosis is not well established. Platelet-rich plasma has been used as an autologous factor ...
Young Annie A Roche Products Ltd, Welwyn Garden City, - - 2012
Dalcetrapib, a cholesteryl ester transfer protein modulator, under development to increase high-density lipoprotein cholesterol and potentially decrease cardiovascular risk, will potentially be co-prescribed to women on oral contraceptive (OC). Assess the effect of dalcetrapib on the pharmacokinetics and ability to suppress ovulation of Microgynon® 30, a representative monophasic OC. A ...
Tapley Heather - - 2012
The following article reads the protagonist in Sarah Schulman's Girls, Visions and Everything as not only lesbian, but as hobosexual-a concept representative of anti-capitalist practices in both sex and labor. The hobosexual is developed as an extension of the lesbian flâneur, as a concept that requires reading Schulman's urban lesbian ...
Luce Edward A EA Department of Plastic Surgery, University of Tennessee, Memphis, TN, - - 2012
Efforts to limit resident work hours are conceptually flawed. A fundamental solution to resident service requires funding, which currently is not feasible. An equally fundamental structuring of the system of surgical resident education is feasible and should be attained.
Silverpil Elin - - 2012
Asthma is perceived as a heterogeneous disease with several clinical phenotypes and triggering factors. In general, cytokines from T-helper 2 cells are believed to be critical contributors of asthma. In recent years, IL-17, another T-helper lymphocyte-associated cytokine, has been put forward as another potentially important mediator of asthma. Currently, several ...
Lakin Gregory E GE Section of Plastic and Reconstructive Surgery, Department of Surgery, University of Michigan Health Systems, Ann Arbor, MI 48109, - - 2012
The pathoetiology of craniosynostosis is not well understood. It likely results from a combination of genetic and epigenetic phenomena, such as intrauterine constraint from multiple gestations. Information on craniosynostosis in twins is limited to case reports and series. The authors conducted a systematic review and meta-analysis of the literature to ...
Vellante Marcello - - 2012
ABSTRACT: Unusual subjective experiences are relatively common in the general population and have been associated with an increased level of vulnerability to psychosis. The current study aimed to a) determine the distribution of hallucination-like experiences (HLEs) in a community sample of young adults, b) investigate their dimensional subtypes, and c) ...
Voshaar Thomas T Krankenhaus Bethanien, Moers, IMS Health, Frankfurt, - - 2012
Asthma is one of the most common chronic diseases worldwide. Patient persistence with treatment is essential to achieve sufficient outcomes, in particular to avoid exacerbations. To investigate inhaled corticosteroid (ICS) therapy with two different inhalers (Novolizer® and Turbuhaler®) by comparing persistence, concomitant use of additional asthma medication and occurrence of ...
Portelli Michael - - 2012
There is heterogeneity in patient responses to current asthma medications. Significant progress has been made identifying genetic polymorphisms that influence the efficacy and potential for adverse effects to asthma drugs, including; β(2)-adrenergic receptor agonists, corticosteroids and leukotriene modifiers. Pharmacogenetics holds great promise to maximise clinical outcomes and minimize adverse effects. ...
Tatewaki Y - - 2012
Reports on the MRI findings of cerebral corticosubcortical lesions in osmotic myelinolysis (OM) are rare despite several pathological descriptions of this involvement. We report two patients with subcortical lesions associated with OM that were characteristically distributed along the crowns and sides of the cerebral gyri on T(2) weighted or fluid-attenuated ...
Fukui S - - 2012
The aim of this study was to investigate the early and mid term results of total laparoscopic bypass for aortoiliac occlusive lesions. From December 2001 to January 2007, we performed 32 laparoscopic bypasses for aortoiliac lesions. The mean age was 52.9 years. Clinical stages included: severe intermittent claudication (N.=24) ischemic ...
Micheli Lucia - - 2012
Objective: Although hypoglycemia is known to be associated with levofloxacin, patients are continually being hospitalized because of this adverse event. Here we have reported two further cases of severe hypoglycemia and discussed the possibility that the hypoglycemia is the result of interactions between levofloxacin and certain drugs, in order to ...
Forsberg Sune - - 2012
Objectives. The hospital mortality from acute poisoning in the western world is approximately 0.6%. However, this figure is based on series of consecutive cases, including mild intoxications. The aim of this paper was to investigate the mortality among poisoned patients with CNS depression on admission. Design. This report is based ...
Volkova Evgeniya - - 2012
Rio Bravo virus (RBV) is a member of the family Flaviviridae, genus Flavivirus. It belongs to a group of viruses in the genus with no known vector. In this report, we analyze the complete genome of the prototype RBV, strain M64.
Aschen Seth S Divisions of Plastic and Reconstructive Surgery and Breast Surgery, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, - - 2012
Although fat deposition is a defining clinical characteristic of lymphedema, the cellular mechanisms that regulate this response remain unknown. The goal of this study was to determine how lymphatic fluid stasis regulates adipogenic gene activation and fat deposition. Adult female mice underwent tail lymphatic ablation and were euthanied at 1, ...
Sucher Robert R Research Laboratory Innsbruck Medical University Anichstrasse 35 A-6020 Innsbruck, Austria. - - 2012
Rat models of experimental face transplantation have been widely used to study vascularized composite tissue allotransplantation. Because the mouse represents a superior species for vascularized composite tissue allotransplantation research, the authors developed a novel surgical technique with which to perform hemiface transplantation in mice. BALB/c hemifacial grafts were transplanted into ...
Ichiki M M Department of Radiology, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan. - - 2012
The purpose of this study was to evaluate the MRI characteristics of venous thrombus over set time thresholds with histopathological correlation in a porcine model. Inferior vena cava thrombi were induced in 12 pigs. MRI was performed in three pigs 2 h, 1 day, 3 days and 2 weeks after ...
Luce Edward A EA Department of Plastic Surgery, University of Tennessee, Memphis, TN, USA. - - 2012
The roots of the working hours mandate and controversy are outlined, the effect on resident education is described, and the service versus education equation is defined.
Fransson Bo - - 2012
The novel Type B gamma-aminobutyric acid (GABAB)-receptor agonist lesogaberan (AZD3355) has been evaluated as an add-on to proton pump inhibitor treatment for gastroesophageal reflux disease, but the effect of food on the bioavailability of this compound has not been assessed. In this openlabel crossover study, healthy males received single 100 ...
Sigal Leonard H - - 2012
ABSTRACT: In physiological systems, for every "yang," there must be a "yin," for uncontrolled systems can run amok. This is the case for the T-cell compartment of the immune system, where activation must be modulated, dampened, and ultimately reversed; to not apply the brakes leads to dire consequences. In less ...
Kurajoh Masafumi - - 2012
Although hyperuricemia is suggested to increase allantoin production in both pro- and antioxidant manners, it remains undetermined whether it increases the serum concentration of allantoin. In addition, since uric acid has both pro- and antioxidant actions, a decrease in the serum concentration of uric acid may have an effect on ...
Iezzoni Lisa I - - 2012
OVERVIEW: This narrative is related in the alternating voices of the two authors. One author, a 55-year-old man, quadriplegic from primary progressive multiple sclerosis, describes the 10 weeks he spent in four facilities for treatment of a stage IV ischial pressure ulcer. The other author, his friend and health care ...
Trimarchi S - - 2012
In-hospital outcome of acute type B dissection (ABAD) is strongly related to preoperative aortic conditions. In order to clarify the influence of the clinical presentation on the outcome, we analyzed the patients of the International Registry of Acute Aortic Dissection (IRAD). All patients affected by complicated ABAD, enrolled in the ...
Shim S S - - 2012
The purpose of this study was to review radiological images of patients with Paragonimus westermani (PW) that simultaneously involved the chest and abdomen. Our study included four patients with serologically and histopathologically confirmed paragonimiasis. Abdomen CT (n=3) and chest CT (n=3) scans were available, and abdominal wall ultrasonography was performed ...
Karaosmanoglu A D - - 2012
The presence of a small amount of macroscopic fat is not unusual in the hilar region of normal lymph nodes. However, abundant replacement of the lymph node with fat is highly unusual and may appear as metastatic lymph node disease in the course of fat-predominant liposarcomas or in the case ...
Kayser John W - - 2012
More than 1 million people in the United States use home oxygen therapy and its demand is growing. However, there are dangers associated with its use, such as burns and home fires, and smoking is the most common cause of these incidents. As a result, home healthcare nurses feel intense ...
Kniemeyer H W - - 2012
Spontaneous recanalization of the internal carotid artery (ICA) is rarely observed. Mainly case reports are published. Most often early recanalization occurs within days or weeks and only a few cases of late recanalization months or years after detected occlusion are reported. Symptomatic bilateral ICA occlusion is regarded as an acceptable ...
Losken Albert A Emory Division of Plastic Surgery 550 Peachtree Street, Suite 84300 Atlanta, GA 30308, USA. - - 2012
There is an ongoing debate about the reliability of various lower abdominal flaps for breast reconstruction. The authors evaluate in vivo perfusion of these flaps to objectively determine which techniques and which skin island zones had better perfusion. A prospective study was performed on 77 single-pedicle breast reconstructions [pedicled transverse ...
Oertel-Knöchel Viola - - 2012
ABSTRACT: This is the first study to combine psychometric and functional neuroimaging methods to study altered patterns of autobiographical memory in bipolar disorder (BD). All participants were interviewed with an expanded version of the Bielefelder Autobiographical Memory Inventory (Bielefelder Autobiographisches Gedächtnis Inventar 2004;Lisse: Swets and Zeitlinger). We then acquired functional ...
McRobbie D W - - 2012
This article reviews occupational exposure in clinical MRI; it specifically considers units of exposure, basic physical interactions, health effects, guideline limits, dosimetry, results of exposure surveys, calculation of induced fields and the status of the European Physical Agents Directive. Electromagnetic field exposure in MRI from the static field B(0), imaging ...
Anil G - - 2012
Surgery is the standard treatment for the extremely rare pathology of isolated anomalous systemic arterial supply to normal lung (ISSNL). We describe our experience with this anomaly in a 29-year-old male presenting with recurrent haemoptysis that was successfully treated with a combination of metallic coils and cyanoacrylate glue. In addition ...
Levitt Heidi M - - 2012
Sexual minority women were divided into four groups to study their gender identities (butch and femme), and gender expression (traditionally gendered and non-traditionally gendered women who do not identify as butch or femme). Experiences of heterosexist events (discrimination, harassment, threats of violence, victimization, negative emotions associated with these events), mental ...
Nagy Michael W MW Plastic Surgery of the Face and Body 1967 Highway 34 Suite 102 Wall, NJ 07719, USA. - - 2012
No scientific comparative study has demonstrated any statistically significant clinical improvement attributable to a new lipoplasty technology relative to traditional suction-assisted lipoplasty. This prospective study used a contralateral study design to evaluate postoperative differences between vibration amplification of sound energy at resonance (VASER)-assisted lipoplasty and suction-assisted lipoplasty. Twenty female patients ...
Zhang Wei - - 2012
Objective: This thorough QT/ QT interval corrected for heart rate (QTc) study was designed to assess the potential of semagacestat, a functional gamma-secretase inhibitor, to delay cardiac repolarization. Methods: In this Phase I, single-dose, randomized, 4-period crossover study, semagacestat was compared with placebo in 54 healthy male and female subjects ...
O╩╝donovan David A DA Division of Plastic Surgery, The Hospital for Sick Children Center for Craniofacial Care and Research, The Hospital for Sick Children Research Institute, University of Toronto, Toronto, Ontario, - - 2012
The authors previously established an animal model of radiation-induced craniofacial bone growth inhibition and demonstrated the effectiveness of cytoprotection in preserving growth using amifostine, but the mechanism is unclear. The objective of this study was to investigate the acute and long-term histopathologic effects of single-dose orthovoltage irradiation on craniofacial bone ...
Tchanque-Fossuo Catherine N CN University of Michigan Medical School, the University of Michigan, MI 48109-5340, - - 2012
Radiotherapy, a cornerstone of head and neck cancer treatment, causes substantial morbidity to normal adjoining bone. The authors assessed the radioprotective effect of amifostine therapy on the mineralization of the mandible using micro-computed tomography. They hypothesized that amifostine would safeguard the mandible from radiation-induced disruption of the mineralization process and ...
Deng Songqing - - 2012
Oxcarbazepine (OXC) is widely registered for the treatment of partial seizures and generalized tonic-clonic seizures (GTCS). Myoclonic seizures induced by OXC are uncommon. We report a child with idiopathic generalized epilepsy who developed myoclonic seizures and had an abnormal electroencephalogram (EEG) when oral suspension of OXC was introduced. This study ...
Macsali Ferenc - - 2012
Gender differences in respiratory health have, in recent years, been the focus of considerable scientific effort. This paper reviews recent literature on respiratory health in women in relation to age at menarche, menstrual cycle, irregular menstruation, polycystic ovarian syndrome, menopause and exogenous sex hormones. This literature provides substantial evidence that ...
Van Den Berg J C - - 2012
In-stent restenosis after endovascular treatment of stenotic and occlusive disease of the infrainguinal arteries is still a clinical challenge. In this paper an overview of the current status of drug-eluting balloon technology and results of clinical trials with drug-eluting balloon angioplasty is given. Furthermore a case series of 10 patients ...
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