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Chamberlain Marc C - - 2012
Glioblastoma (GBM) is the most common malignant primary brain tumor, which despite combined modality treatment, recurs and is invariably fatal. New therapies for GBM represent an unmet need in neuro-oncology. This review provides an overview of the epidemiology and molecular biology of GBM and focuses, in particular, on integrins, which ...
Choi Won-Gyu - - 2012
Many plant response systems are linked to complex dynamics in signaling molecules such as Ca(2+) and reactive oxygen species (ROS) and to pH. Regulatory changes in these molecules can occur in the timeframe of seconds and are often limited to specific subcellular locales. Thus, to understand how Ca(2+) , ROS ...
Gotlib Jason - - 2012
Mast cells and eosinophils often travel in the same biologic circles. In non-clonal states, such as allergic and inflammatory conditions, cell-to-cell contact and the pleiotropic actions of multiple cytokines and chemokines, derived from local tissues or mast cells themselves, foster the co-recruitment of these cells to the same geographic cellular ...
Chen Jia-Min - - 2012
Hookworm infection is a relatively common cause of anemia in endemic areas. The most common hookworm species are Ancylostoma duodenale and Necator americanus. In this report we present a case of overt gastrointestinal bleeding because of hookworm infection. Capsule endoscopy revealed many hookworms in the lumen of proximal jejunum where ...
Li Stella - - 2012
Studies have shown that in adult animals the medial prefrontal cortex (mPFC) is a critical brain region involved in fear regulation, with the prelimbic (PL) subregion being important for fear expression. However, few studies have examined whether the PL cortex is also involved in fear expression in infant animals. Five ...
Banfi Carlo - - 2012
Pheochromocytoma is a catecholamine-secreting tumor associated with clinical presentations ranging from paroxysmal hypertension to intractable cardiogenic shock. We report the use of central extracorporeal life support (ECLS) in a young woman admitted to the intensive care unit with cardiogenic shock. Her medical history included neurofibromatosis type I and pheochromocytoma. ECLS ...
Rajapakse Senaka - - 2012
Scrub typhus is a zoonosis caused by the pathogen Orientia tsutsugamushi (O. tsutsugamushi). The disease has significant prevalence in eastern and Southeast Asia. Usually presenting as an acute febrile illness, the diagnosis is often missed because of similarities with other tropical febrile infections. Many unusual manifestations are present, and these ...
Rohlf Thimo - - 2012
Epigenetic mechanisms play an important role in regulating and stabilizing functional states of living cells. However, in spite of an increasing amount of experimental data, models of transcriptional regulation by epigenetic processes, in particular by histone modifications, are rather rare. In this article, we focus on epigenetic modes of transcriptional ...
Arias Cesar A - - 2012
The treatment of infections caused by vancomycin-resistant enterococci (VRE) has become an important clinical challenge and compromises the care of critically ill patients. A striking increase in the frequency of nosocomial isolation of multidrug-resistant Enterococcus faecium has dramatically reduced the therapeutic alternatives because the majority of E. faecium isolates are ...
Huang Guofu - - 2012
Purpose: To evaluate reasons for non-compliance with post-cataract surgical follow-up in rural China, and assess the impact of incentives on improving compliance. Methods: Patients having undergone cataract surgery more than 3 months previously at cataract surgery training hospitals in Guangdong were invited by telephone and advertisements to a hospital-based study ...
Zafar Abdul Mueed - - 2012
Although intervention in asymptomatic carotid artery stenosis remains controversial, most carotid interventions are performed in asymptomatic individuals. Carotid duplex ultrasound is the diagnostic test that precedes more than 90% of carotid interventions. In terms of economic incentives, providers who perform carotid artery revascularization may experience synergy if they also provide ...
Jones Roger W - - 2012
Samples of haploid and hybrid seed from three different maize donor genotypes after maternal haploid induction were used to test the capability of automated near-infrared transmission spectroscopy to individually differentiate haploid from hybrid seeds. Using a two-step chemometric analysis in which the seeds were first classified according to genotype and ...
Stewart C - - 2012
AIm: To examine the reasons for referral to the Paediatric Dental Department, Cork University Dental School and Hospital, Ireland and to study the profile of these reasons in terms of the various sources of referral. Clinical review. Consecutive clinical records for children attending the service were reviewed with regard to ...
Eme Robert - - 2012
This review examines the long-standing finding that ADHD is a common sequela of pediatric traumatic brain injury (PTBI) in light of the current conceptualization of ADHD as a dimensional, neuropsychologically heterogeneous disorder. The review contends that this conceptualization established the basis for concluding that frequently occurring symptoms caused by PTBI, ...
Seifert-Klauss V - - 2012
ABSTRACT Decreasing rates of ovulation, hormonal changes, and increasing bone loss pre-date menopause by several years. Data suggest that, in addition to estradiol, progesterone may play a significant role in the interrelationship between the ovaries and the skeleton in women. Indeed, the differentiation of human osteoblasts from perimenopausal women has ...
Arias-Rivas S - - 2012
INTRODUCTION. Hospital-based population studies are a good way to determinate the number and features of strokes that occur in a given society. The major stroke subtypes have different patterns of incidence and outcome, for that reason information on the natural history of stroke subtypes is essential. AIM. To determine the ...
Oddershede Lars - - 2012
A short saphenous vein segment is commonly used as a conduit for coronary artery bypass grafting, and clinicians must decide whether to obtain it by performing open (OVH) or endoscopic vein harvest (EVH). We conducted a health economic evaluation, using data on resource usage collected alongside a randomized controlled trial, ...
Shi Jia-Yu - - 2012
To explore the aesthetic characteristics of the Chinese children lips. Frontal and profile photographs of 653 healthy children were categorized as the attractive and the unattractive by three laypersons and objectively measured for comparison. The attractive group tended to be smaller in the upper paramedian red lip height, the lower ...
de-la-Llave-Rincon A I - - 2012
INTRODUCTION. The symptoms of carpal tunnel syndrome (CTS) vary greatly and can depend on the severity of the clinical symptoms. AIMS. To characterise the description and self-perception of pain in a sample of patients with CTS and to determine whether that perception of pain differs among the patients on the ...
Rankine James J - - 2012
The purpose of this study is to determine the diagnostic accuracy of radiographs in the diagnosis of Lisfranc injury. In addition, a foot phantom was investigated to determine the optimum degree of craniocaudal angulation on the anteroposterior radiograph to best show the joint. The angle of the joint in patients ...
Tani Tomoko - - 2012
We describe a 66-year-old man who required an operation for severe mitral regurgitation associated with a double-orifice mitral valve. Real-time 3-dimensional transesophageal echocardiography clearly demonstrated a double-orifice mitral valve with a central fibrous bridge. A flail posterior leaflet was observed on the anterolateral mitral valve orifice. Mitral valve repair using ...
Haider Abul Fazal Mohammed Yusuf - - 2012
Elemental analyses of kohl (stone) samples collected from three different parts of the world were performed using laser-induced breakdown spectroscopy (LIBS). The analyses indicated that lead (Pb), copper (Cu), silver (Ag), iron (Fe), calcium (Ca), aluminum (Al), silicon (Si), and sodium (Na) were present in all the kohl samples. In ...
Paul Asit K - - 2012
In patients with breast cancer, a number of biomarkers, such as estrogen receptor, progesterone receptor and HER2, are part of routine work-up and used to guide endocrine, cytotoxic and HER2-targeted treatment. Interaction among these markers may also impact on treatment response and is being investigated. Multigene assays have reached varying ...
Oto Murat - - 2012
The aim of this study is to evaluate the outcomes of eight-plate (Orthofix) use during hemiepiphyseodesis operation for growth modulation in obese children with adolescent Blount disease. Six limbs of five consecutive patients who underwent lateral proximal tibial eight-plate (Orthofix) hemiepiphysiodesis were evaluated. The body mass index (BMI) was >30 ...
Olak J - - 2012
Aim: This was to compare the effect of a prevention program between children of anxious and non-anxious mothers. Mothers (n=120) with high and low dental anxiety scores (DAS>15 and DAS <8, respectively), and with high levels of mutans streptococci (>10(5)cfu/mL) were recruited at a maternity clinic of Tartu, Estonia. Two ...
Simon J A - - 2012
The original conclusions of the Women's Health Initiative study have been questioned as a result of the availability of age-stratified data. Initial concerns regarding the risk of coronary heart disease (CHD) in association with the use of hormone replacement therapy (HRT) have been replaced with concerns regarding thromboembolic disease, encompassing ...
Roufosse Florence - - 2012
Hypereosinophilia, defined as peripheral blood eosinophil counts >1,500/μL, may complicate the course of various lymphoproliferative disorders. Among these, Hodgkin lymphoma (HL) and certain peripheral T-cell lymphomas (PTCLs) derived from CD4 cells, including Sezary syndrome (SS), adult T-cell leukemia/lymphoma (ATLL), and angioimmunoblastic T-cell lymphoma (AITL), are most commonly associated with increased ...
Ewing Michael J - - 2012
A 67-year-old woman presented with dyspnea on exertion and a diminished left radial pulse in comparison with the right. She had signs and symptoms of cardiac tamponade. A computed tomographic (CT) angiogram of the chest revealed an aortic arch pseudoaneurysm along the lesser curvature and a large pericardial effusion with ...
Brian Garry - - 2012
Purpose: To determine the use of medical services for eye problems in Fiji, and barriers to seeking that care. Methods: An interview-based questionnaire was administered as part of a population-based cross-sectional survey of adults selected by multistage random sampling from those aged ≥40 years living on Fiji's main island. Results: ...
Carvalho Manuela C - - 2012
In emergency/clinical practice it is often necessary to restore the balance of blood coagulation: the rapid reversal of oral anticoagulant therapy (OAT) is crucial in cases of serious acute bleeding and emergency surgery in patients with high international normalized ratios (INRs). Coagulation can be normalized via the application of haemostatic ...
Kim Tae Ki - - 2012
The purpose of our study was to assess the acceptable compression threshold for JPEG2000 compression of CT images used for measuring coronary artery calcification scores (CACS) in terms of variability. In a retrospective review, 80 patients who had undergone CT for determination of the CACS were compiled in four subsets ...
Yoo Eun Young - - 2012
The aim of this study was to evaluate the diagnostic contribution of BRAF(V600E) mutation analysis from the fine-needle aspiration (FNA) specimens of calcified thyroid nodules. From January 2008 to December 2008, 139 patients with 139 calcified thyroid nodules prospectively underwent BRAF(V600E) mutation analysis and ultrasound-guided FNA. At ultrasound, the patterns ...
Zhang Chang-Hua - - 2012
Management of presacral hemorrhage is always challenging. Herein we describe the use of an absorbable hemostatic gauze with α-cyanoacrylate medical adhesive to achieve hemostasis. In this study, we conducted total mesorectal excision for the treatment of rectal cancer in 258 patients from March 2006 to May 2009. Intraoperative presacral hemorrhage ...
Cruz Anleu Israel Didier - - 2012
Tuberculosis is one of the conditions with higher incidence worldwide. Infection occurs when Mycobacterium enters the body, and its progression to disease occurs when immune, nutritional and vaccination status are altered. The diagnosis in children is based on elements such as contact history, tuberculin test, chest radiograph and microbiological finding ...
Shinzawa Hideyuki - - 2012
Hydrolysis degradation of a set of drawn poly(lactic acid) (PLA) fibers was induced by an accelerated weathering test, radiating ultraviolet (UV) light under a certain temperature and humidity. The fine features of the transient behavior of the PLA fibers were captured by near-infrared (NIR) hyperspectral imaging. The PLA fibers showed ...
Neghina Raul - - 2012
Malaria is a major problem for European travelers to endemic regions. In Romania during 1980-2007 approximately 20 imported cases were detected annually. The aim of our short communication is to present 2 interesting cases of imported malaria detected in Western Romania. The first patient was a 20-year female who traveled ...
Panos Aristotelis - - 2012
Video assistance can replace sternotomy in cardiac operations with excellent results. Because myxomas are very friable tumors, their removal from the heart and chest cavity through a working port in video-assisted or robotic procedures may be challenging. We used a laparoscopic basket to safely catch and remove these friable tumors ...
Al Bahry Saif - - 2012
To determine the effect of nalidixic acid on the morphology and protein expression of Pseudomonas aeruginosa (P. aeruginosa). Nalidixic acid solution of 1 600 μg/mL was prepared. The minimum inhibitory concentration (MIC) for P. aeruginosa was determined with tube dilution test. The effect of nalidixic acid on the morphology of ...
Kasprowicz Victoria O - - 2012
IFN-γ release by antigen-specific T cells can be used to track immune responses to infections and vaccines. In recent years, there have been substantial advances in the techniques available to measure IFN-γ release and a generation of such assays are now available for clinical use, as well as in a ...
Butts Janie B - - 2012
Nurses have long attempted to secure a unique identity for the profession. Many scholars are now promoting an interdisciplinary framework for nursing practice. Fawcett is convinced that interdisciplinary practice poses a danger for nursing to lose its identity and that interdisciplinary practice cannot be successful if members of each discipline ...
Rojas Carlos A - - 2012
In this article, we describe how we constructed a radiology teaching file that simulates real-life scenarios and discuss some of the advantages it affords. Using OsiriX imaging software and iWork Pages, we have created a HIPAA-compliant interstitial lung disease radiology teaching resource that allows the user to navigate through the ...
Santiago Inês - - 2012
The purpose of this essay is to illustrate the imaging findings of congenital cystic lesions of the biliary tract. Congenital cystic lesions of the biliary tract include ductal plate malformations and choledochal cysts and can be recognized with characteristic imaging findings and basic knowledge of the embryologic development of the ...
Kemerink Martijn - - 2012
This article will provide an assessment of the application of x-rays in the early days of radiology, which is an excellent way to come to value the convenience and safety of modern x-ray systems. The gas tubes that were originally applied for x-ray production were very unstable because of variations ...
Wang Page I - - 2012
The objectives of this article are to discuss the current evidence-based recommendations regarding the use of diagnostic imaging in the evaluation of pulmonary embolism, appendicitis, urolithiasis, and cholelithiasis during pregnancy. Diagnostic imaging should be performed during pregnancy only with an understanding of the maternal and fetal risks and benefits, the ...
Chintapalli Kedar N - - 2012
The purpose of this article is to discuss radiation dose during CT-guided interventions and to explain how radiologists can modify technical factors to minimize radiation doses. Scanner-displayed indexes of radiation exposure that are available during the procedure will be defined to increase awareness about CT radiation dose reduction during interventional ...
Langer Steve G - - 2012
The objective of this article is to provide an overview of the considerations that are faced when a film-based imaging department transitions to a filmless practice. Both departmental and enterprise issues will be discussed in the context of a single geographically confined campus. A successful transition to a filmless practice ...
Tsui Gary Kin-wai - - 2012
Patient data may appear as burned-in text on the image content of DICOM image files, which is commonly seen in ultrasound images and some secondarily scanned images. The purpose of this article is to discuss the removal of such information, which can be cumbersome and demands human intervention. This article ...
Wang Page I - - 2012
The objectives of this article are to discuss the current evidence-based recommendations regarding radiation dose concerns, the use of iodinated and gadolinium-based contrast agents, and the comparative advantages of multimodality imaging (ultrasound, CT, and MRI) during pregnancy and lactation. We also discuss the use of imaging to evaluate pregnant trauma ...
Grand David J - - 2012
We report acute onset of either odynophagia or abdominal pain immediately after ingestion of grilled meat in six patients presenting between May 1, 2009, and November 18, 2010. In all six patients, radiologic studies revealed a linear metallic foreign body. Careful history revealed cleaning of the grill with a metallic ...
Maldjian Pierre D - - 2012
The location, number, size, and configuration of intimal tears in aortic dissection have important therapeutic and prognostic implications. Planning of procedures to treat complications of aortic dissection may require precise delineation of the intimal tears. The purpose of this article is to illustrate the ability of MDCT using multiplanar image ...
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