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Results 301 - 350 of 2590
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Wang Yu - - 2012
A new rhodamine-based reversible chemosensor (2) was synthesized, which exhibits high sensitivity and selectivity for Cu(2+) but no significant response toward other competitive metal ions in aqueous solution. Upon the addition of Cu(2+), the spirolactam ring of 2 was opened and the solution color changed from colorless to red. Strangely, ...
Corcoran Anthony T AT Department of Urology, University of Pittsburgh School of Medicine, Suite 700 Kaufmann Medical Building, 3471 Fifth Avenue, Pittsburgh, PA 15213, - - 2013
This study investigated the cytokine profile in bladder tissue and urine of painful bladder syndrome/interstitial cystitis (PBS/IC) patients. Multiplex analysis of 23 cytokines was performed with a multiple antigen bead assay (Luminex 100 IS) on cold cup bladder biopsy and urine specimens collected during cystoscopy with hydrodistention (HD) under general ...
Riar Sandeep - - 2012
Chylous ascites (CA) is an unusual complication of pediatric abdominal surgery which can be difficult to manage. Little data are available to guide therapy. We describe the presentation, clinical course and management of two patients, a 7-year-old boy and 2.5-year-old girl, who experienced CA following intraperitoneal renal transplantation. Both cases ...
Saito Masaya - - 2012
BACKGROUND: Transcatheter arterial chemoembolization (TACE) is an effective treatment for hepatocellular carcinoma (HCC), but it sometimes makes liver function worse. The pre-TACE prediction of liver dysfunction after TACE would be helpful to avoid long-term liver dysfunction. METHODS: We performed a case-control study in 100 HCC patients who underwent TACE at ...
Stingl L - - 2012
BACKGROUND: Hsp90 inhibitors can enhance the tumour sensitivity to ionising radiation (IR). However, Hsp90 inhibition leads to the up-regulation of anti-apoptotic Hsp90 and Hsp70, which might diminish the radiosensitizing effects of the inhibitors. Therefore, inhibition of the up-regulation of Hsp90 by siRNA might be a promising strategy to enhance drug-mediated ...
Yamamoto Toshiyuki - - 2012
Pustulotic arthro-osteitis (PAO) is occasionally seen in patients with palmoplantar pustulosis (PPP); however, its pathogenesis is still obscure. Herein, two patients with PAO associated with PPP were described. Both patients developed hydrarthrosis on the knees, along with sternocostoclavicular pain. Detail examination revealed odontogenic infection in both cases. Matrix metalloproteinase-3 (MMP-3) ...
Salonia Andrea - - 2012
PURPOSE: We sought the association of preoperative serum total testosterone (tT), hypogonadism, 17β estradiol (E(2)), and sex hormone-binding globulin (SHBG) with early biochemical recurrence (BCR) after radical prostatectomy (RP). METHODS: Sex steroids were assessed the day before surgery (7-11 a.m.) in a cohort of 605 patients with a median follow-up ...
Roghani Tayebeh - - 2012
The aim of this study is to evaluate the effect of submaximal aerobic exercise with and without external loading on bone metabolism and balance in postmenopausal women with osteoporosis (OP). Thirty-six volunteer, sedentary postmenopausal women with OP were randomly divided into three groups: aerobic, weighted vest, and control. Exercise for ...
Bandeali Salman - - 2012
Levels of high-density lipoprotein (HDL) cholesterol are generally inversely associated with the risk for the development of atherosclerosis. The mechanism by which HDL imparts protection from the initiation and progression of occlusive vascular disease is complex and multifactorial. The major anti-atherosclerotic effect of HDL is felt to be reverse cholesterol ...
Bahng Hee Won - - 2012
It has been demonstrated that the direction and magnitude of transition dipole moments, and hence rates in the excitation energy hopping in the self-assembled porphyrin boxes can be tuned by insertion of ethynyl groups as well as the dielectric constant of solvent.
Becker Robert E - - 2012
This paper responds to the fact that over 200 Alzheimer's disease (AD) drug candidates have failed to date and draws on searches of the literature for studies of error effects in drug developments and the authors' published works. In the same period, basic knowledge of AD pathology has greatly expanded ...
Matsumoto Takuya - - 2012
Green-colored plastids in the dinoflagellates Lepidodinium chlorophorum and L. viride have been widely believed as the remnant of an endosymbiotic prasinophyte. This hypothesis for the origin of the Lepidodinium plastids is solely based on an unpublished result quoted in Elbrächter and Schnepf (Phycologia 35:381-393, 1996) hinting at the presence of ...
Hahm Myung Gwan - - 2012
High-density carbon nanotube networks (CNNs) continue to attract interest as active elements in nanoelectronic devices, nanoelectromechanical systems (NEMS) and multifunctional nanocomposites. The interplay between the network nanostructure and its properties is crucial, yet current understanding remains limited to the passive response. Here, we employ a novel superstructure consisting of millimeter-long ...
Louati Hela - - 2012
PURPOSE: The main goals of this study were to investigate (1) the behavior of microbial communities in response to low-dose bioavailable anthracene addition in lightly contaminated sediment from Bizerte Lagoon and (2) the effects of bioremediation treatments on microbial biomass, activity, and community structure. METHODS: Sediment microcosms amended with 1 ppm ...
Konjevic Gordana - - 2012
NK cells have become a subject of investigation not only in the field of tumor immunology and infectious diseases, but also within all aspects of immunology, such as transplantation, autoimmunity, and hypersensitivity. Our early studies aside from investigating NK cell activity in experimental animals and humans included studies of perforin ...
Streuli Isabelle - - 2012
Introduction: Endometriosis, histologically defined as the presence of endometrium-like tissue - glands and stroma - that develops outside of the uterine cavity, is still an enigmatic disease responsible for pelvic pain and infertility. The current treatments of endometriosis are surgery and hormonal therapies that act by suppressing ovulation and/or directly ...
Baghdadi G - - 2012
Hypnosis is a mental state or set of attitudes usually induced by a procedure known as hypnotic induction. In order to provide the basic physiological conditions for potentially successful hypnosis treatment of medical and psychological problems, the determination of a subject's hypnotizability level is important. Currently, the hypnotizability level is ...
Di Giacomo Dina - - 2012
Changes in semantic memory are a controversial topic in research on cognitive decline in aging. In this study, we analyzed whether the semantic deficits in mild Alzheimer's disease (AD) reflect the information acquisition process, and whether the deficits are related to when the information was initially stored. We hypothesized that ...
Castellano-Hernández E - - 2012
Electrostatic force microscopy has been shown to be a useful tool to determine the dielectric constant of insulating films of nanometer thicknesses that play a key role in many electrical, optical and biological phenomena. Previous approaches have made use of simple analytical formulas to analyze the experimental data for thin ...
Niehaus Isak - - 2012
Durkheim's classical theory of suicide rates being a negative index of social solidarity downplays the salience of gendered concerns in suicide. But gendered inequalities have had a negative impact: worldwide significantly more men than women perpetrate fatal suicides. Drawing on narratives of 52 fatal suicides in Bushbuckridge, South Africa, this ...
Saccheri Paola - - 2012
We observed a sternal foramen contiguous with a small sternal cleft in a human skeleton coming from North-Eastern Italy and dating back to between the sixteenth and seventeenth century AD. Both of these types of anomalies result from a defective midline fusion of the developing sternum. Sternal foramen is a ...
Pinto Evelin - - 2012
Objective: To report the outcomes from two cases of ovarian stimulation following the sole administration of gonadotrophin-releasing hormone agonist (GnRHa) in the context of in vitro fertilization (IVF). Design: A case study was conducted. Setting: National Referral Unit of Reproductive Medicine. Patients: Two infertile women undergoing IVF participated in the ...
Morandi Bill - - 2012
Diazomethane is a common and versatile reagent in organic synthesis whose broader use is generally impeded by its explosiveness and toxicity. Here we report that a simple iron porphyrin complex catalyzes the cyclopropanation of styrenes, enynes, and dienes under the demanding conditions [aqueous 6 molar potassium hydroxide (KOH) solution, open ...
Munger Corey M - - 2012
Mantle cell lymphoma (MCL) is an aggressive B-cell neoplasm with few patients achieving long-term survival with current treatment regimens. High-dose therapy is effective in reducing the tumor burden; however, patients eventually relapse due to minimal residual disease. Having demonstrated efficacy in other malignancies, the effectiveness of dendritic cell-based immunotherapy for ...
Lam Vy - - 2012
There is an urgent need for rapid, accurate, and sensitive diagnostic platforms to confirm exposure to radiation and estimate the dose absorbed by individuals subjected to acts of radiological terrorism, nuclear power plant accidents, or nuclear warfare. Clinical symptoms and physical dosimeters, even when available, do not provide adequate diagnostic ...
Thakur Garima - - 2012
Amyloid-fibril formation in human serum albumin (HSA) led to hydrogel formation in the presence of clusters of bismuth ferrite (BiFeO(3) or BFO) nanoparticles (NPs). Factors responsible for hydrogel formation were size and phase of NPs.
Ptasinska-Wnuk Dorota - - 2012
The local renin-angiotensin system (RAS) is present in the pituitary gland, and inhibitory effects of angiotensins on the lactosomatotroph (GH3) cell growth have been revealed. The aim of this study was to examine the influence of various angiotensin peptides and angiotensin AT1, AT2, and AT4 receptors antagonists on the cell ...
Morrison Clare - - 2012
Recovery planning is a key component of many threatened species conservation initiatives and can be a powerful awareness raising tool. One of the largest impediments to conservation efforts in the Pacific region however, is the lack of ecological data and its subsequent effects on the development of feasible and useful ...
Thümler Anke - - 2012
OBJECTIVE: To assess clinical features and general health status of adult patients with mucopolysaccharidosis (MPS) VI. METHODS: This report includes the clinical history of patients older than 18 years with slowly progressing MPS VI and the retrospective analysis of the outcomes of available data collected between September 2003 and October 2008 ...
Gayzik F S - - 2012
The purpose of this study was to acquire external landmark, undeformed surface, and volume data from a pre-screened individual representing a mid-sized male (height 174.9 cm, weight 78.6 ± 0.77 kg) in the seated and standing postures. The individual matched the 50th percentile value of 15 measures of external anthropometry ...
Saravanan Govindachetty - - 2012
Intermetallic Pt(3)Ti nanoparticles are solubilized in water by using a generation-five, hydroxyl-terminated, poly(amidoamine) dendrimer, G5OH, as a post-synthesis surfactant. Pt(3)Ti nanoparticles, encapsulated in G5OH and dispersed over the electrode surface, exhibited a superior catalytic activity toward the electro-reduction reaction of oxygen compared to as-prepared, highly agglomerated nanoparticles.
Cowey Alan A Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK. - - 2012
In three hemianopic monkeys and one normal monkey who subsequently became hemianopic and in one human hemianope we measured reaction times to touch the remembered position of a brief visual target presented in the normal hemifield or in the blind hemifield, or on the blank trials where no visual target ...
Bowmaker Graham A - - 2012
The complex [(Ph(3)P)(2)Ag(H(2)cit)]·EtOH (; H(2)cit(-) = dihydrogencitrate = C(6)H(7)O(7)(-)) contains [(Ph(3)P)(2)Ag(H(2)cit)] molecules in which the silver atom is coordinated to two PPh(3) molecules and the two oxygen atoms of one of the 'terminal'/1-carboxylate groups of the dihydrogencitrate group. The molecules form centrosymmetric hydrogen-bonded dimers in the solid. In [{(Ph(3)P)(2)Ag}(2)(Hcit)], (), ...
Messerschmidt Daniel M DM Mammalian Development Group, Institute of Medical Biology, - - 2012
Phenotypic variability in genetic disease is usually attributed to genetic background variation or environmental influence. Here, we show that deletion of a single gene, Trim28 (Kap1 or Tif1β), from the maternal germ line alone, on an otherwise identical genetic background, results in severe phenotypic and epigenetic variability that leads to ...
Donkin Chris - - 2012
A classic question in cognitive psychology concerns the nature of memory search in short-term recognition. Despite its long history of investigation, however, there is still no consensus on whether memory search takes place serially or in parallel or is based on global access. In the present investigation, we formalize a ...
Sabbagh Charles - - 2012
BACKGROUND: Short-stay laparoscopic appendectomy for acute appendicitis (AA) has not yet been validated. This study was designed to prospectively evaluate the hospital length of stay (LOS) after laparoscopic appendectomy for AA and to determine predictive factors for successful short-stay surgery (LOS <24 h). METHODS: Between January and December 2010, all consecutive ...
Jarl Gustav M - - 2012
Purpose: To evaluate the validity of a modified version of the Orthotics and Prosthetics Users' Survey (OPUS) with persons using different prosthetic and orthotic (P&O) devices.Method: Two-hundred-and-eighty-two adults using prosthesis, orthosis, shoe insoles or orthopaedic shoes completed OPUS. OPUS comprises five modules - Lower and Upper Extremity Functional Status, respectively ...
Peters Sanne A E - - 2012
Abstract Objective: Sample size calculations for clinical trials generally use expected changes between groups, and variances obtained from the literature. However, this approach neglects the impact of differences in trial design. We studied the effects of variations in trial design on the required sample size. Methods: Data were used from ...
Matsui Hitoshi - - 2012
Analysis of biliary metabolites is essential to predict pharmacokinetics and hepatotoxicity during drug development. In this paper, we present a hepatocyte culture configuration that enables the direct recovery of bile acid that accumulates in bile canaliculi by embedding the hepatocytes in a 3D micropatterned collagen gel substrate. We investigated the ...
Anandan Srinivasan - - 2012
Amorphous Cu(ii) nanoclusters grafted WO(3) particles were coated on a smooth TiO(2) film, and site selective depositions of PbO(2) and metal Ag particles by photocatalytic processes were observed on TiO(2) and WO(3) due to transfer of holes to TiO(2), and accumulation of electrons in WO(3) respectively. As a result, the ...
Rhoades Brittany L - - 2012
Although numerous evidence-based programs (EBPs) have been proven effective in research trials and are being widely promoted through federal, state, and philanthropic dollars, few have been "scaled up" in a manner likely to have a measurable impact on today's critical social problems. The Interactive Systems Framework for Dissemination and Implementation ...
Schmerr Nicholas - - 2012
The lithosphere-asthenosphere boundary (LAB) beneath ocean basins separates the upper thermal boundary layer of rigid, conductively cooling plates from the underlying ductile, convecting mantle. The origin of a seismic discontinuity associated with this interface, known as the Gutenberg discontinuity (G), remains enigmatic. High-frequency SS precursors sampling below the Pacific plate ...
Bauer Stefan - - 2012
Automatic scan planning for magnetic resonance imaging of the knee aims at defining an oriented bounding box around the knee joint from sparse scout images in order to choose the optimal field of view for the diagnostic images and limit acquisition time. We propose a fast and fully automatic method ...
Santos Jucimary V - - 2012
Objective: The aim of this study was to adjust the zidovudine (AZT) release from solid tablets to an ideal profile, by developing matrices comprising swellable polymers with nonswellable ones. Methods: Directly compressed matrices comprised different ratios of hydroxypropylmethylcellulose K15M and K100M, ethylcellulose, and methacrylic acid (Eudragit(®) RS PO and Eudragit(®) ...
Ossenkoppele Rik - - 2012
PURPOSE: [(11)C]PIB and [(18)F]FDDNP are PET tracers for in vivo detection of the neuropathology underlying Alzheimer's disease (AD). [(18)F]FDG is a glucose analogue and its uptake reflects metabolic activity. The purpose of this study was to examine longitudinal changes in these tracers in patients with AD or mild cognitive impairment ...
Muñoz María Paz - - 2012
Transition metal catalysed hydroalkoxylation of allenes has received much attention in recent years, and both the intra- and intermolecular versions have been reported. Gold(i) complexes are among the most active catalysts for these processes. This critical perspective article will cover the progress in this field, analysing the intermolecular metal-catalysed reaction ...
Rule Susan - - 2012
Giant vertebrates dominated many Pleistocene ecosystems. Many were herbivores, and their sudden extinction in prehistory could have had large ecological impacts. We used a high-resolution 130,000-year environmental record to help resolve the cause and reconstruct the ecological consequences of extinction of Australia's megafauna. Our results suggest that human arrival rather ...
Kamath Sushant U - - 2012
This review aims to explore the toxicological aspects of mercury-based herbo-metallic preparations like cinnabar and "Rasasindura" that are primarily composed of mercuric sulfide (HgS). Cinnabar-containing preparations have been used extensively in Indian and Chinese systems of medicine for treatment of chronic ailments like syphilis, high fever, pneumonia, insomnia, nervous disorders, ...
Busl M - - 2012
We theoretically analyze electronic spin transport through a triple quantum dot in series, attached to electrical contacts, where the drain contact is coupled to the central dot. We show that current rectification is observed in the device due to current blockade. The current blocking mechanism is originated by a destructive ...
Stouffer Daniel B - - 2012
Studies of ecological networks (the web of interactions between species in a community) demonstrate an intricate link between a community's structure and its long-term viability. It remains unclear, however, how much a community's persistence depends on the identities of the species present, or how much the role played by each ...
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