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Results 351 - 400 of 3232
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Douxfils Jonathan - - 2012
Due to low bioavailability and high inter-individual variability, monitoring of dabigatran may be required in specific situations to prevent the risk of bleedings or thrombosis. The aim of the study was to determine which coagulation assay(s) could be used to assess the impact of dabigatran on secondary haemostasis. Dabigatran was ...
Ahmed Imtiaz - - 2012
An 8-week feeding trial was conducted to determine the dietary tryptophan requirement of fingerling Indian catfish, Heteropneustes fossilis (6.10 ± 1.15 cm, 4.44 ± 0.50 g). Six isonitrogenous (40 g 100 g(-1)) and isoenergetic (17.90 kJ g(-1)) amino acid test diets were formulated with gradation of 0.1 g 100 g(-1) containing graded levels of L: -tryptophan (0.04-0.54 g 100 g(-1), dry diet). Fish were stocked in triplicate ...
Carlsson Maria E - - 2012
Objective:The aim of the present pilot study was to investigate insomnia, sleep quality, and daytime sleepiness in relatives of dying patients cared for at home.Method:The study has a descriptive, comparative, and cross-sectional design. The sample consisted of relatives of patients cared for through palliative home care in Uppsala County on ...
Karl Jenni M JM Department of Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada. - - 2012
The reach-to-grasp movement is composed of a number of movement elements including hand transport, hand shaping, and grasping. These movement elements are featured in grasping when it is guided by vision, when it is guided by haptic input from the non-reaching hand or other body parts, and when it is ...
Nikoo Shohreh - - 2012
Aim:  Menstrual blood stromal stem cells (MBSCs) have been demonstrated to exhibit stem cell properties such as the capability for self-renewal and multipotency, allowing for multilineage differentiation. In addition, this cell type has various immunomodulatory effects. In this study, we examined the potential effect of MBSCs on proliferation of peripheral ...
Kaiser Lee D - - 2012
Stratified permuted blocks randomization is commonly applied in clinical trials, but other randomization methods that attempt to balance treatment counts marginally for the stratification variables are able to accommodate more stratification variables. When the analysis stratifies on the cells formed by crossing the stratification variables, these other randomization methods yield ...
Stefani Alessandro - - 2012
Recently, it is under scrutiny the possibility to anticipate the stereotactic implantation of the subthalamic nucleus (STN) even in relatively mild Parkinson's disease (PD) patients with an unsatisfying response to drugs. In addition, it is debated whether levodopa (LD) and deep brain stimulation (DBS) are congruent or, instead, mutually exclusive. ...
Fang Ming - - 2012
Tissue cryo-sectioning combined with atomic force microscopy imaging reveals that the nanoscale morphology of dermal collagen fibrils, quantified using the metric of D-periodic spacing, changes under the condition of estrogen depletion. Specifically, a new subpopulation of fibrils with D-spacings in the region between 56 and 59 nm is present 2 years ...
Xiao Jian - - 2012
The unprecedented cooperative systems involving a diarylprolinol silyl ether with various Lewis acids have been found to effect the highly enantioselective intermolecular α-alkylation of aldehydes. A wide variety of aldehydes and alcohols can be transformed into the desired highly functionalized aldehydes in high yields, excellent enantioselectivities, and good diastereoselectivities at ...
Klöck Cornelius - - 2012
A number of lines of evidence suggest that transglutaminase 2 (TG2) may be one of the earliest disease-relevant proteins to encounter immunotoxic gluten in the celiac gut. These and other investigations also suggest that the reaction catalyzed by TG2 on dietary gluten peptides is essential for the pathogenesis of celiac ...
Kurth Florian F Department of Medicine, Center for Neurobiology of Stress, School of Medicine, University of California-Los Angeles, CA 90095, USA. - - 2013
Numerous studies suggest that interhemispheric inhibition-relayed via the corpus callosum-plays an important role in unilateral hand motions. Interestingly, transcallosal inhibition appears to be indicative of a strong laterality effect, where generally the dominant hemisphere exerts inhibition on the nondominant one. These effects have been largely identified through functional studies in ...
Mézešová Lucia - - 2012
The study was focused to the influence of higher intake of cholesterol on properties of the renal Na,K-ATPase, a key system in maintaining the homeostasis of sodium in the organism. Feeding for 4 weeks with cholesterol-enriched food for rats afflicted with hereditary hypertriglyceridemia by itself enhanced the activity of Na,K-ATPase, ...
Ladjici Y - - 2012
INTRODUCTION: We compared single incision laparoscopic surgery with flexible endoscope ("flexible SILS") and with rigid optic ("rigid SILS") for access to 11 elective sites of peritoneal carcinomatosis. MATERIALS AND METHODS: Back-to-back flexible and rigid SILS peritoneoscopy were performed in ten live pigs. SILS peritoneoscopy was performed using a flexible endoscope ...
Hommel Kevin A - - 2012
To cite this article: Hommel KA, Franciosi JP, Gray WN, Hente EA, Ahrens A, Rothenberg ME. Behavioral functioning and treatment adherence in pediatric eosinophilic gastrointestinal disorders. Pediatr Allergy Immunol 2012: 00. ABSTRACT: Objective:  To examine behavioral predictors of treatment adherence in patients with eosinophilic gastrointestinal disorders (EGID). Methods:  Participants were ...
Lamaita Rívia Mara - - 2012
Aim:  Inflammation is as an important factor in ovulation with the active participation of leucocytes and their inflammatory mediators. The present study was performed to compare the activity of the inflammatory enzymes myeloperoxidase (MPO) and N-acetylglucosaminidase (NAG) in patients with endometriosis-related infertility and in normally ovulating women undergoing intracytoplasmic sperm ...
Horckmans Michael - - 2012
Communication between endothelial cells and cardiomyocytes is critical for cardiac development and regeneration. However the mechanisms involved in these endothelial-cardiomyocyte interactions remain poorly understood. Nucleotides are released within the heart, especially under ischemia or pressure overload. The function of P2Y nucleotide receptors in cardiac development has never been investigated. Here ...
Sharafutdinov A U - - 2012
The cotunneling current through a two-level quantum dot weakly coupled to ferromagnetic leads is studied in the Coulomb blockade regime. The cotunneling current is calculated analytically under simple but realistic assumptions as follows: (i) the quantum dot is described by the universal Hamiltonian, (ii) it is doubly occupied, and (iii) it displays a ...
Williams Victoria J VJ Neuroimaging Research for Veterans Center, VA Boston Healthcare System, Boston, Massachusetts, - - 2013
Prior research has demonstrated links among vascular health and the occurrence of stroke, mild cognitive decline, and dementia in older adults. However, little is known about whether normal variation in vascular indicators may be related to changes in neural tissue integrity. Even less is known about how the brain is ...
Li Xing-Jun - - 2012
Reactions of a tripodal ligand, N,N',N″-tris(3-pyridinyl)phosphoric triamide (TPPA), and a series of transition-metal ions result in the assembly of five discrete M(6)L(8) coordination cages [M(6)(TPPA)(8)(H(2)O)(12)](ClO(4))(12)·57H(2)O [M = Ni(2+) (1), Co(2+) (2), Zn(2+) (3), Cd(2+) (4)] and [Pd(6)(TPPA)(8)]Cl(12)·22H(2)O (5). X-ray structural analyses reveal that the cages have large internal cavities and ...
Srivastava Rajesh K - - 2012
The metabolic reaction rate vector is a bridge that links gene and protein expression alterations to the phenotypic endpoint. We present a simple approach for the estimation of flux distribution at key branch points in the metabolic network by using substrate uptake, metabolite secretion rate, and biomass growth rate for ...
Nordby Pernille - - 2012
Health benefits of physical activity may depend on a concomitant weight loss. In a randomized, controlled trial we compared the effects of endurance training with or without weight loss to the effect of weight loss induced by an energy-reduced diet in 48 sedentary, moderately overweight men who completed a 12-week ...
Guermache Fatiha - - 2012
Aims:  To simplify the determination of the nuclear condition of the pathogenic Rhizoctonia, which currently needs to be performed either using two fluorescent dyes, thus more costly and time-consuming or using only one fluorescent dye, thus less accurate. Methods and Results:  A red primary fluorescence (Autofluorescence) of the hyphal cell ...
Sun Ya-Qiu - - 2012
Five new 2D coordination polymers, [Co(nip)(CuL)(H(2)O)]·CH(3)OH (), [Mn(ip)(NiL)]·0.63H(2)O (), [Cu(ip)(CuL)] (), [Mn(6)(CuL)(6)(btc)(4)(H(2)O)(4)]·7H(2)O (), and [Cu(CuL)(Hbtc)(H(2)O)] ()(ML, H(2)L = 2,3-dioxo-5,6,14,15-dibenzo-1,4,8,12-tetraazacyclo-pentadeca-7,13-diene; H(2)nip = 5-nitroisophthalic acid; H(2)ip = m-isophthalic acid; H(3)btc = 1,3,5-benzenetricarboxylic acid) have been synthesized by a solvothermal method and characterized by single-crystal X-ray diffraction. Complexes exhibit different 2D layered structures ...
Pfuhl Gerit - - 2012
There are simple co-occurrences as well as functional relationships between events. One may assume that animals detect and use causation rather than mere co-variation. However, understanding causation often requires concepts of hidden forces. In string pulling, obstacles may hamper the access to food. Here, I studied whether ravens have an ...
Hutchison R Matthew - - 2012
Characterization of large-scale brain networks using blood-oxygenation-level-dependent functional magnetic resonance imaging is typically based on the assumption of network stationarity across the duration of scan. Recent studies in humans have questioned this assumption by showing that within-network functional connectivity fluctuates on the order of seconds to minutes. Time-varying profiles of ...
Wang Hua-Wei - - 2012
Himalayas was believed to be a formidably geographical barrier between South and East Asia. The observed high frequency of the East Eurasian paternal lineages in Nepal led some researchers to suggest that these lineages were introduced into Nepal from Tibet directly; however, it is also possible that the East Eurasian ...
Janarthanan Krishnaveni - - 2012
A 2-y-old girl presented with recurrent abdominal pain and hematemesis. The patient was diagnosed to have chronic calcific pancreatitis complicated by pseudocyst of the head of pancreas and pseudo-aneurysm of the common hepatic artery. Diagnosis was made using abdominal ultrasonography and CT angiography. The rarity of the presentation of pseudocyst ...
Moghaddam Banaem Lida - - 2012
Aim:  The aim of this study was to determine the relationship between maternal serum C-reactive protein (CRP) levels in the first 20 weeks of pregnancy and later occurrence of preterm premature rupture of membranes and preterm birth. Material and Methods:  A prospective cohort study that measured maternal serum CRP levels in ...
Nciri Riadh - - 2012
Recent studies suggest that lithium protects neurons from death induced by a wide array of neurotoxic insults, stimulates neurogenesis and could be used to prevent age-related neurodegenerative diseases. In this study, SH-SY5Y human neuronal cells were cultured in the absence (Con) or in the presence (Li+) of a low lithium ...
Zezza L - - 2012
BACKGROUND: In human patients with interstitial cystitis, intravesical instillation of alkalinized lidocaine sometimes is associated with sustained amelioration of symptoms beyond the acute treatment phase. Interstitial cystitis shares many features in common with feline idiopathic cystitis. OBJECTIVE: To evaluate whether intravesical instillation of alkalinized lidocaine decreases recurrence of urethral obstruction ...
Ginde Salil - - 2012
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital heart lesion that if left untreated, results in high mortality. Surgical treatment options include reimplantation of the anomalous coronary ostia, use of extracardiac arterial blood supply, or the Takeuchi procedure. The Takeuchi procedure involves ...
Smith Elliot J - - 2012
A review of present and future on-chip rolled-up devices, which can be used to develop lab-in-a-tube total analysis systems, is presented. Lab-in-a-tube is the integration of numerous rolled-up components into a single device constituting a microsystem of hundreds/thousands of independent units on a chip, each individually capable of sorting, detecting ...
Patti Gary J - - 2012
Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry. With emerging technologies in mass spectrometry, thousands of metabolites can now be quantitatively measured from minimal amounts of biological material, which has thereby enabled systems-level analyses. By performing global metabolite profiling, also known as ...
Sun Shao-Kai - - 2012
A simple and efficient colorimetric method for the naked-eye detection and quantification of histidine in biological fluids was developed based on an indicator-displacement assay (IDA) and the Ni(2+)-histidine affinity pair. In this IDA approach, a commercially available dye, murexide, was used as the indicator and the selective detection of histidine ...
He Bice - - 2012
A molecular ensemble composed of a phenothiazine (PTZ) electron donor, a photoisomerizable dithienylethene (DTE) bridge, and a Ru(bpy)(3)(2+) (bpy = 2,2'-bipyridine) electron acceptor was synthesized and investigated by optical spectroscopic and electrochemical means. Our initial intention was to perform flash-quench transient absorption studies in which the Ru(bpy)(3)(2+) unit is excited ...
Teunissen Marcel B M - - 2012
There is limited information available regarding the phenotype and function of leukocytes involved in the earliest stages of psoriatic lesion development. In this study, we examined the presence of different types of leukocytes in psoriatic point lesions collected at three 1-week interval time points from a recent and simultaneously formed ...
Kim Byungwoo - - 2012
We demonstrate the high performance of supercapacitors fabricated with vertically aligned carbon nanotubes and nonaqueous electrolytes such as ionic liquids and conventional organic electrolytes. Specific capacitance, maximum power and energy density of the supercapacitor measured in ionic liquid were ∼75 F g(-1), ∼987 kW kg(-1) and ∼27 W h kg(-1), respectively. The high power performance was consistently ...
Hsiao Hao-Ming - - 2012
The drug-eluting stent (DES) has become the gold standard worldwide for the treatment of cardiovascular diseases. In recent years, an innovative variation of the DES with micro-sized drug reservoirs has been introduced. It allows programmable drug delivery with both spatial and temporal control and has several potential advantages over traditional ...
Gebhard Cathérine - - 2012
Tissue factor (TF) is the key activator of coagulation and is involved in acute coronary syndromes. Caffeine is often reported to increase cardiovascular risk; however, its effect on cardiovascular morbidity and mortality is controversial. Hence, this study was designed to investigate the impact of caffeine on endothelial TF expression in ...
Labrie Julien - - 2012
Stress urinary incontinence (SUI) is a bothersome condition affecting health-related quality of life (HRQoL) to a great extent in women. From a patient's perspective, improving HRQoL is probably equally important as objective cure of SUI. Our objective was to assess the effect of pelvic floor muscle training (PFMT) and midurethral ...
Guan Weijie - - 2012
Abstract Background: Although leukotriene D4 (LTD4) was a potent bronchoconstrictor, little is known about airway responsiveness to LTD4 in asthmatics with different inflammation phenotypes. Objectives: To establish the methodology and investigate the distribution characters of airway responsiveness, diagnostic value and safety of LTD4 bronchial provocation test. Methods: LTD4 bronchial provocation ...
Schöllnberger H - - 2012
The non-cancer mortality data for cerebrovascular disease (CVD) and cardiovascular diseases from Report 13 on the atomic bomb survivors published by the Radiation Effects Research Foundation were analysed to investigate the dose-response for the influence of radiation on these detrimental health effects. Various parametric and categorical models (such as linear-no-threshold ...
Kimani Peter K - - 2012
Hommel (Biometrical Journal; 45:581-589) proposed a flexible testing procedure for seamless phase II/III clinical trials. Schmidli et al. (Statistics in Medicine; 26:4925-4938), Kimani et al. (Statistics in Medicine; 28:917-936) and Brannath et al. (Statistics in Medicine; 28:1445-1463) exploited the flexible testing of Hommel to propose adaptation in seamless phase II/III ...
Noble Louise J - - 2012
BACKGROUND: The relationship between percutaneous endoscopic gastrostomy (PEG) insertion and gastro-oesophageal reflux disease (GERD) is widely disputed in the current literature. The aim of this systematic review is to examine the available evidence documenting the association between PEG and GERD. METHODS: The following databases were searched: MEDLINE (1950 to week ...
Lekberg Ylva - - 2012
In flowering plants, soil heterogeneity can generate divergent natural selection over fine spatial scales, and thus promote local adaptation in the absence of geographic barriers to gene flow. Here, we investigate phenotypic and genetic differentiation in one of the few flowering plants that thrives in both geothermal and non-thermal soils ...
Taki Yasuyuki - - 2012
Although elevated serum high-sensitivity C-reactive protein (hsCRP) is related to atherosclerosis, brain infarction, and cognitive decline, it has not been clarified whether increased hsCRP is associated with the decline in brain gray matter volume. Therefore, the purpose of this study was to determine the relationship between hsCRP levels and brain ...
Sosale Guruprasad - - 2012
Energy dissipation by internal friction is a property of fundamental interest for probing the effects of scale on mechanical behavior in nanocrystalline metallic films and for guiding the use of these materials in the design of high-Q micro/nanomechanical resonators. This paper describes an experimental study to measure the effects of ...
Brewer George J - - 2012
In this special issue about biofactors causing cognitive impairment, we present evidence for and discuss two such biofactors. One is excess copper, causing neuronal toxicity. The other is zinc deficiency, causing neuronal damage. We present evidence that Alzheimer's disease (AD) has become an epidemic in developed, but not undeveloped, countries ...
Hannan Md Abdul - - 2012
Neurotrophic factors are vital not only to support neuronal development but also to protect mature neurons from atrophy in neurodegenerative diseases. As an effort to explore natural sources that possess neurotrophic activity, we screened common marine algae for their neuritogenic activity in the developing rat hippocampal neurons in culture. Of ...
Abbing-Karahagopian Victoria - - 2012
To cite this article: Abbing-Karahagopian V, van der Gugten AC, van der Ent CK, Uiterwaal C, de Jongh M, Oldenwening M, Brunekreef B, Gehring U. Effect of endotoxin and allergens on neonatal lung function and infancy respiratory symptoms and eczema. Pediatric Allergy Immunology 2012: 00. ABSTRACT: Background:  Exposure to endotoxin ...
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