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Stirman Shannon Wiltsey SW Women's Health Sciences Division, National Center for PTSD, VA Boston Healthcare System, 150 S. Huntington Ave (116B3), Boston, MA 02130, USA. - - 2013
Policymakers are investing significant resources in large-scale training and implementation programs for evidence-based psychological treatments (EBPTs) in public mental health systems. However, relatively little research has been conducted to understand factors that may influence the success of efforts to implement EBPTs for adult consumers of mental health services. In a ...
Costello Leslie C LC Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, 650 West Baltimore Street, Baltimore, MD 21201, USA. - - 2012
Pancreatic adenocarcinoma is an untreatable cancer with a 5-year survival rate of about 6 % or less for the past 35 years. This lack of significant progress is largely due to the lack of elucidation and understanding of the factors involved in the development of this cancer. Recent studies identified and ...
Kawada Natsuko - - 2012
Gemcitabine is a key drug for the treatment of pancreatic cancer. Human equilibrative nucleoside transporter 1 (hENT1) is a major transporter responsible for gemcitabine uptake into cells. This study was conducted to elucidate the association between expression level of hENT1 and outcome for pancreatic cancer patients treated with neoadjuvant therapy ...
Fu Hongyun H Population Services International, Kunming, - - 2012
We distinguish between selection and true migration effects on weight and body fat for Vietnamese immigrants; and examine the role of acculturation on these outcomes. Data (n = 703) were collected among three population-based samples of working-age Vietnamese immigrants, repatriated emigrants and never-migrated Vietnamese nationals. This allows for a decomposition ...
Kurd Mark F - - 2012
A retrospective cohort study. In this article, we examined the Spine Patient Outcomes Research Trial lumbar stenosis observational cohort to determine baseline patient characteristics that are predictive of the treatment patients chose. We also evaluated cutoff points on validated patient questionnaires that differentiate patients who chose surgery from those who ...
Monshouwer K - - 2012
The present study examined the joint development of substance use and externalizing problems in early and middle adolescence. First, it was tested whether the relevant groups found in previous studies i.e., those with an early onset, a late onset, and no onset or low levels of risk behavior could be ...
Zaller Nickolas D ND Division of Infectious Diseases, The Miriam Hospital, Providence, RI, USA. - - 2012
Access to sterile syringes for injection drug users (IDUs) is a critical part of a comprehensive strategy to combat the transmission of HIV, hepatitis C virus, and other bloodborne pathogens. Understanding IDUs' experiences and attitudes about syringe acquisition is crucial to ensuring adequate syringe supply and access for this population. ...
Abu Raya Bahaa - - 2012
Eighty-two isolates of Bordetella pertussis analyzed by pulsed-field gel electrophoresis from the epidemic years, 2007 to 2008, revealed 4 strains with 2 closely related isolates accounting for 95% of the circulating strains. The most common Israeli strain has the same pulsed-field gel electrophoresis cluster as the dominant European BpSR11 strain ...
Schow Eric V EV Department of Chemistry, University of California, Irvine, CA 92697-2025, - - 2012
Voltage-dependent potassium (Kv), sodium (Nav), and calcium channels open and close in response to changes in transmembrane (TM) potential, thus regulating cell excitability by controlling ion flow across the membrane. An outstanding question concerning voltage gating is how voltage-induced conformational changes of the channel voltage-sensing domains (VSDs) are coupled through ...
Bhogal Maninder S - - 2012
To investigate the effects of adhesion promoting surgical adjuncts in Descemets stripping automated endothelial keratoplasty (DSAEK). The effects of air-fill pressure, duration, use of venting incisions and stromal roughening on fluid dispersion, and donor adhesion strength were examined in theoretical, optical coherence tomography (OCT), and strain gauge models of DSAEK. ...
Ferriss James Stuart JS Thornton Gynecologic Oncology Service, Department of Obstetrics and Gynecology, University of Virginia Health System, Charlottesville, VA, USA. - - 2012
The objective of the study was to determine if initial surgery (IS) or initial chemotherapy (IC) affects rates of optimal surgery and survival in a population with significant medical comorbidities. Data of all patients with stage III-IV ovarian, peritoneal, and fallopian tube cancers diagnosed from 1995 to 2008 were reviewed. ...
Nakao Shintaro - - 2012
The current treatments against inflammatory angiogenesis are steroids and anti-VEGF-A, such as dexamethasone and bevacizumab, respectively. However, the therapeutic windows for dexamethasone and bevacizumab against inflammatory angiogenesis are unknown. To investigate the therapeutic windows for dexamethasone and bevacizumab, we used the corneal pocket assay. IL-1β pellets were implanted in corneas ...
Rao Ruta - - 2012
The treatment of breast cancer is continually evolving. Standard treatment for early stage, node positive breast cancer has included adjuvant chemotherapy. As we learn more about differences in a tumor's genetic makeup that result in different patterns of recurrence and survival, we are starting to include gene expression in addition ...
Gasparetto Francesco - - 2012
Over the decades, arthroscopy has grown in popularity for the treatment of many foot and ankle pathologies. While anterior ankle arthroscopy is a widely accepted technique, posterior ankle/subtalar arthroscopy is still a relatively new procedure. The goal of this review is to outline the indications, surgical techniques, and results of ...
Perumal Jai - - 2012
The past two decades have seen tremendous expansion in therapeutic options for multiple sclerosis (MS). While the growing armamentarium of therapies provides physicians and patients an array of available options, it also brings in its wake the challenging responsibility of choosing the optimal therapy for an individual patient. In a ...
Lima Roberta - - 2012
Blood pressure is typically lower in premenopausal women than in men. However, after menopause, the prevalence of hypertension in women is higher than it is in men. Hypertension is a major risk factor for cardiovascular disease in women and men, but cardiovascular disease is the leading cause of death in ...
Vardi Moshe - - 2012
Diabetes mellitus (DM) carries an increased risk for cardiovascular complications. Haptoglobin (Hp) is an abundant plasma protein with an antioxidant function by virtue of its ability to block the oxidative activity of extracorpuscular hemoglobin. There exist two common functional alleles at the Hp genetic locus, denoted 1 and 2, with ...
Ishikawa Joji J Center for Behavioral Cardiovascular Health, Division of General Medicine, Columbia University Medical Center, New York, New York, USA. - - 2012
We evaluated the agreement between office blood pressure (OBP) measured by a mercury sphygmomanometer (Sphyg) and an automatic (Auto) device without any observers, and compared Auto and Sphyg OBP with ambulatory blood pressure (ABP) and home blood pressure (HBP). OBP was measured in 75 hypertensive patients at two sites using ...
Feeney Maria B MB Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS 66047, - - 2012
The understanding of physiological and pathological processes involving protein oxidation, particularly under conditions of aging and oxidative stress, can be aided by proteomic identification of proteins that accumulate oxidative post-translational modifications only if these detected modifications are connected to functional consequences. The modification of tyrosine (Tyr) residues can elicit significant ...
Merlot Angelica M - - 2013
Under normal circumstances, cellular iron levels are tightly regulated due to the potential toxic effects of this metal ion. There is evidence that tumors possess altered iron homeostasis, which is mediated by the perturbed expression of iron-related proteins, for example, transferrin receptor 1, ferritin and ferroportin 1. The de-regulation of ...
Noophan Pongsak Lek - - 2012
Batch experiments were conducted to investigate the effects of oxytetracycline on anaerobic ammonium oxidation (anammox) process. The short-and long-term effects on anammox activity were studied by measuring ammonium (NH(4) (+)), nitrite (NO(2) (-)), and nitrate (NO(3) (-)) concentrations over time. Experiments were conducted at NH(4) (+)and NO(2) (-) concentrations of ...
Tazisong Irenus A - - 2012
To study Hg toxicity on soil microbes and their activities, it is necessary to understand its various forms in soils. The objectives of this study were to investigate Hg speciation in four soil types spiked with Hg (300 mg kg(-1) soil) and its effects on soil microbial respiration and enzymes ...
Hu Ji Y - - 2012
A simple and efficient residue analysis method for direct determination of ioxynil octanoate in maize and soil was developed and validated with High Performance Liquid Chromatography-Ultra Violet (HPLC-UV). The samples were extracted with mixtures of acetonitrile and deionized water followed by Solid Phase Extraction (SPE) to remove co-extractives prior to ...
Faiz Yasir - - 2012
Thirteen road dust and four soil samples were analyzed using instrumental neutron activation analysis (INAA) to determine the elemental composition of road dust collected from Islamabad Expressway. The amounts of most of the elements determined were generally in the lower range of the global data with the exception of Ce, ...
Smičiklas Ivana D - - 2012
Experimental design methodology was applied for evaluation of factors influencing Co(2+) sorption by thermally treated bovine bones. The major aim of this study was to determine factors which affect process the most, as well as their mutual interactions, in order to select conditions that provide maximum sorbent loading. Five process ...
Shatos Marie A MA Schepens Eye Research Institute, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, - - 2012
The purpose of this study was to investigate the presence of progenitor cells in the uninjured, adult rat lacrimal gland (LG). The presence of progenitor cells was examined in LG sections from male rats using antibodies against selected stem cell markers and α-smooth muscle actin (SMA), which marks myoepithelial cells ...
Saha Antonio A Department of Medical Oncology, St. Bartholomew's Hospital, London, United - - 2012
To describe the outcome of primary chemotherapy for women with advanced-stage epithelial ovarian or primary peritoneal cancer and delayed surgery when optimal debulking surgery cannot be achieved at diagnosis. Between 1998 and 2006, we retrospectively reviewed the overall survival and examined prognostic markers in consecutive patients who were not suitable ...
Li Huashou - - 2012
The interaction among the bensulfuron-methyl, growth of Italian ryegrass, and soil chemical/biochemical/microbiological parameters was investigated in a microcosm experiment. The bensulfuron-methyl added to the soil can be rapidly degraded by certain fungi and actinomycetes present in the original paddy rice soil. The growth of Italian ryegrass significantly accelerated the in-soil ...
Sigal Ian A - - 2012
Purpose. Understanding the effects of IOP on the optic nerve head (ONH) is important in understanding glaucoma and ONH structure and function. The authors tested the hypothesis that the ONH is a robust biomechanical structure wherein various factors combine to produce a relatively stable response to IOP. Methods. The authors ...
Razban Behrooz - - 2012
An analytical method to produce profiles of bacterial biomass fatty acid methyl esters (FAME) was developed employing rapid agitation followed by static incubation (RASI) using selective media of wastewater microbial communities. The results were compiled to produce a unique library for comparison and performance analysis at a Wastewater Treatment Plant ...
Lee Edward - - 2012
Our objective was to examine the feasibility of rotating choriocapillaris, Bruch's membrane (BM), and retinal pigment epithelium (RPE) through 180° on a vascular pedicle and to assess revascularization and tissue preservation postoperatively. Such an approach could be used in the treatment of age-related macular degeneration where there is focal disease ...
Lu Chunxue C Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, - - 2012
Chlamydia trachomatis is the leading infectious cause of blindness. The goal of the current study was to search for biomarkers associated with C. trachomatis-induced ocular pathologies. We used a whole genome scale proteome array to systematically profile antigen specificities of antibody responses to C. trachomatis infection in individuals from trachoma-endemic ...
Prakash Gaurav - - 2012
To analyze the intra-user reliability and inter-user reproducibility of assessment of corneal epithelial thickness by Fourier domain optical coherence tomography. In this consecutive cross-sectional case series performed at a tertiary ocular care institution, 210 eyes of 210 subjects underwent anterior segment Fourier domain optical coherence tomography (FDOCT). A caliper tool ...
Wood Joanne M - - 2012
To determine the effect of moderate levels of refractive blur and simulated cataracts on nighttime pedestrian conspicuity in the presence and absence of headlamp glare. The ability to recognize pedestrians at night was measured in 28 young adults (M = 27.6 years) under three visual conditions: normal vision, refractive blur, ...
Liu Yi H - - 2012
The effectiveness of homologous and heterologous formats in a nanocolloidal gold-based immunoassay for pesticide residue determination was investigated. Parathion, one of the most toxic organophosphorus pesticides, was used as the target analyte. One-step homologous and heterologous test strips based on a nanocolloidal gold-labeled monoclonal antibody were developed for the rapid ...
Omae Tsuneaki - - 2012
Although recent clinical trials have demonstrated that fenofibrate is effective for treating diabetic retinopathy, the mechanism of this beneficial effect remains unclear. In the current study, we examined the effect of the vasomotor action of fenofibrate on porcine retinal arterioles. Porcine retinal arterioles (internal diameter, 60-90 μm) were isolated, cannulated, ...
Hanazono Gen - - 2012
The purpose of this study is to determine the topography of bleaching in rods, middle/long-wavelength (M/L) and short-wavelength (S) cones in the macaque retina by using a modified retinal densitometry technique. A modified commercial digital fundus camera system was used to measure continuously the intensity of the light reflectance during ...
Zhang Shenghai - - 2012
Recombinant adeno-associated viral vector serotype 2 (rAAV2) has been used with success to deliver retina-targeted gene therapeutics in retinal degeneration. However, one of the major limitations of this approach is the vector's low transduction efficiency. This study is designed to increase AAV2 transduction efficiency in vitro and in vivo. Green ...
Lu Xian T - - 2012
Previous studies have demonstrated that pesticides could induce cytotoxicity and genotoxicity in vivo and in vitro, and that oxidative stress may be an important factor involved. However, investigations comparing the capability of different organophosphorous (OP) compounds to induce cytotoxicity, genotoxicity and oxidative stress are limited. Hence, the aim of this ...
Lake Sarah L - - 2012
Survival of patients with uveal melanoma (UM) correlates strongly with chromosomal abnormalities, such as monosomy 3 and polysomy 8q. Studies have shown multiplex ligation-dependent probe amplification (MLPA) to detect reliably chromosomal aberrations in UM using frozen samples. To date, the concordance between MLPA data generated from frozen and fixed samples ...
Joo Jin Chul - - 2012
The roles of mineral-bound humic acid (HA) and mineral surfaces in the sorption of six nonpolar neutral organic compounds with relatively high aqueous solubility, S(w) , (1,2,4-trichlorobenzene, 1,4-dichlorobenzene, chlorobenzene, m-xylene, toluene, and benzene) to low-surface-area (i.e., ≤ 1.2 m(2)/g) metal (hydr)oxide- and HA-coated sands with low organic carbon fractions (i.e., ...
Bosco Domenico - - 2012
Pathological gambling (PG) is a potential complication related to the treatment of Parkinson disease (PD) with dopamine agonists (DA). The cause of this disorder is unknown, but altered dopamine neurotransmission may be involved. We evaluated the efficacy and tolerability of the opioid antagonist naltrexone in the treatment of PG in ...
Poulter James A - - 2012
Familial exudative vitreoretinopathy (FEVR) is an inherited disorder that disrupts the development of the retinal vasculature and can result in blindness. FEVR is genetically heterogeneous and mutations in four genes, NDP, FZD4, LRP5, and TSPAN12, encoding components of a novel ligand-receptor complex that activates the Norrin-β-catenin signaling pathway, account for ...
Afonso-Olivares Cristina - - 2012
This work presents an effective sample preparation method for the evaluation of seven pharmaceutical compounds belonging to different therapeutic classes in purified water from wastewater treatment plants (WWTPs). The target compounds include caffeine (stimulant), nicotine (stimulant), atenolol (beta blocker), metamizole (anti-inflammatory and analgesic), fluoxetine (antidepressant), paraxanthine (stimulant) and clofibric acid ...
Jiang W - - 2012
Acetogenic bacteria Acetitomaculum ruminis, Acetobacterium woodii, and Eubacterium limosum were compared for phosphoenolpyruvate (PEP) and ATP-dependent phosphorylation of glucose and 2-deoxy-glucose. Rate of phosphorylation activity was measured in toluene-treated acetogenic cells using PEP and ATP and radiolabled glucose or 2-deoxy glucose. Eubacterium limosum, most likely has a glucose phosphotransferase system ...
Clark Robert A RA Department of Ophthalmology, University of California, Los Angeles, CA 90095-7002, - - 2012
The lateral rectus (LR) and medial rectus (MR) extraocular muscles (EOMs) have largely nonoverlapping superior and inferior innervation territories, suggesting functional compartmental specialization. We used magnetic resonance imaging (MRI) in humans to investigate differential compartmental activity in the rectus EOMs during head tilt, which evokes ocular counter-rolling, a torsional vestibulo-ocular ...
Akbari Ahmad - - 2012
Novel nanofibrous membrane was fabricated by using electrospinning of wastage fuzzes of mechanized carpet which was used to remove the dye of the textile wastewater. SEM images showed that nanofibers with average diameters of 200 nm were successfully fabricated by electrospinning technique. The physicochemical properties of electrospun nanofiberous membranes were ...
Hassan Shirin E - - 2012
The purpose of this study is to measure the accuracy and reliability of normally sighted, visually impaired, and blind pedestrians at making street crossing decisions using visual and/or auditory information. Using a 5-point rating scale, safety ratings for vehicular gaps of different durations were measured along a two-lane street of ...
Angunawela Romesh I - - 2012
To measure real-time intraocular pressure (IOP) during trephination with a manual suction trephine (MST) and the femtosecond laser (FSL), and to assess endothelial cell damage, incision geometry, and wound healing response with these procedures. IOP was monitored with an intracameral sensor. Eight rabbits underwent manual suction trephination. Eight rabbits had ...
Zhang Z B - - 2012
Adsorption isotherms of 4 estrogenic compounds, estrone, 17β-estradiol, 17α-ethinylestradiol and Bisphenol A, using molecularly imprinted polymer were studied. The isotherms can be simulated by Langmuir model. According to the adsorption isotherms and the template's mass balance, an experimental concept, selective adsorption ratio, SAR, was proposed to assess how many template ...
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