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Results 451 - 500 of 3126
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Terashi Hiroo - - 2012
Abstract Background: Although freezing of gait (FOG) is reportedly caused by cerebrovascular disease, few studies have examined its pathology. We examined regional cerebral blood flow (rCBF) patterns in patients with FOG resulting from chronic lacunar infarction using single photon emission computed tomography (SPECT). Methods: Among patients with chronic lacunar infarction ...
Hu Yuling - - 2012
In this work we demonstrated a facile method for in situ fabrication of the Fe(3+)-1,3,5-benzenetricarboxylic acid (BTC) metal-organic coordination polymer gel in a capillary, which was efficiently applied to the online enrichment of trace polycyclic aromatic hydrocarbons (PAHs) in environmental water and amphetamines drugs in urine.
Kim Kwang-Min - - 2012
Abstract Objectives. Erosive esophagitis (EE) may be related to small intestinal bacterial overgrowth (SIBO) because gastro-esophageal reflux disease has been a comorbid condition of irritable bowel syndrome (IBS), which has been associated with SIBO. We conducted a pilot study to investigate whether EE was associated with SIBO. Material and methods. ...
Coughlin Shaun - - 2012
BACKGROUND: Enterocutaneous fistulas are abnormal connections between the skin and gastrointestinal tract that most commonly occur after surgery. Somatostatin analogues have been used in their treatment. The objective of the present study was to determine if somatostatin analogues shorten the time to closure of postoperative enterocutaneous fistulas compared to placebo. ...
Petersen Helen Høgh - - 2012
PURPOSE: The study aim was to evaluate patient acceptance and content with remote follow-up (FU) of their implantable cardioverter defibrillator (ICD) and to estimate patients' wish for changes in remote follow-up routines. METHODS: Four hundred seventy-four ICD patients at the device follow-up clinic at Rigshospitalet using CareLink® (Medtronic) remote follow-up, ...
Varadarajan Prakash - - 2012
PURPOSE: There is no information regarding the toxicity associated with autologous hematopoietic progenitor cell transplantation (AHPCT) in patients with multiple myeloma (MM) who have bisphosphonate-induced osteonecrosis of the jaw (ONJ). There is also limited information regarding long-term outcome of these patients. METHODS: In this retrospective cohort study, we compared the ...
Fairchild Barbara A - - 2012
The breakdown of the diamond lattice is explored by ion implantation and molecular dynamics simulations. We show that lattice breakdown is strain-driven, rather than damage-driven, and that the lattice persists until 16% of the atoms have been removed from their lattice sites. The figure shows the transition between amorphous carbon ...
Carrasco Mario - - 2012
New quadruply bonded dimolybdenum complexes of the terphenyl ligand Ar(Xyl(2)) (Ar(Xyl(2)) = C(6)H(3)-2,6-(C(6)H(3)-2,6-Me(2))(2)) have been prepared and structurally characterized. The steric hindrance exerted by the Ar(Xyl(2)) groups causes the Mo atoms to feature unsaturated four-coordinate structures and a formal fourteen-electron count.
Goryawala Mohammed - - 2012
Somatosensory-evoked potentials (SSEPs) have been widely used for intra-operative neurophysiological monitoring (IONM). Currently at least 200-300 trials are required to generate a readable SSEP signal. This study introduces a novel approach that yields accurate detection results of the SSEP signal yet with a significantly reduced number of trials, resulting in ...
Terwilliger Thomas C TC Los Alamos Institutes and BioScience Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. - - 2012
The combination of algorithms from the structure-modeling field with those of crystallographic structure determination can broaden the range of templates that are useful for structure determination by the method of molecular replacement. Automated tools in phenix.mr_rosetta simplify the application of these combined approaches by integrating Phenix crystallographic algorithms and Rosetta ...
Hladik Michelle L - - 2012
Pyrethroid insecticides are hydrophobic compounds that partition to streambed sediments and have been shown to cause toxicity to non-target organisms; their occurrence is well documented in parts of California, but there have been limited studies in other urban and agricultural areas across the United States. To broaden geographic understanding of ...
Bendjelid Karim - - 2012
Conflicting results have been found regarding correlations between right atrial pressure (RAP) and inferior vena cava (IVC) diameter in mechanically ventilated patients. This finding could be related to an increase in intra-abdominal pressure (IAP). This study was designed to clarify whether variations in IVC flow rate caused by positive pressure ...
Salegio E A - - 2013
We have previously shown that adeno-associated virus type 2 (AAV2) undergoes anterograde axonal transport in rat and non-human primate brain. We screened other AAV serotypes for axonal transport and found that AAV6 is transported almost exclusively in a retrograde direction and, in the same way as AAV2, it is also ...
Bernhardsson Carolina - - 2012
When a phenotypic trait is subjected to spatially variable selection and local adaptation, the underlying genes controlling the trait are also expected to show strong patterns of genetic differentiation because alternative alleles are favoured in different geographical locations. Here, we study 71 single nucleotide polymorphisms (SNPs) from seven genes associated ...
Zhang Qingyou - - 2012
AimThis study was designed to investigate the value of history taking in identifying children with cardiac syncope, and to improve diagnostic efficiency and accuracy in children with cardiac syncope.Methods and ResultsWe compared the characteristics of a group of children and adolescents with cardiac syncope at the Pediatric Syncope Unit of ...
Pollscheit Juliane - - 2012
The neural cell adhesion molecule (NCAM) plays a fundamental role during development and regeneration. NCAM is expressed in three major isoforms, two of them with intracellular domains of different length and one without any intracellular domain. The cytoplasmic domain of NCAM contains, depending on the isoform, up to 49 phosphorylation ...
Atalar B - - 2012
We aimed to compare dosimetric characteristics of conventional linear accerator-based treatment plans to those created using the robotic CyberKnife(r) (CK) treatment planning system for patients with early-stage lung cancer. Eight early-stage lung cancer patients treated with stereotactic body radiotherapy (SBRT) using a conventional linac-based (LIN) system were included in this ...
Berr Claudine - - 2012
Preventing cognitive impairment and dementia in the elderly is a major public health challenge for our century and all hypotheses should be explored. Selenium (Se) is one of the factors that may affect the risk of cognitive decline. Its importance in the health and aging process has been documented. Because ...
Goeders Nicholas E - - 2012
Despite increased education regarding its dangers, cigarette smoking remains a significant public health concern due to serious associated health consequences such as cancer and respiratory and cardiovascular diseases. Most smokers fail in their attempts to quit smoking, and current pharmacological interventions have relatively low levels of efficacy and are associated ...
Silva Pedro Henrique Imenez - - 2012
The Na(+/)H(+) exchanger isoform 3 (NHE3) is essential for HCO (3) (-) reabsorption in renal proximal tubules. The expression and function of NHE3 must adapt to acid-base conditions. The goal of this study was to elucidate the mechanisms responsible for higher proton secretion in proximal tubules during acidosis and to ...
Peura Sari - - 2012
Lakes have a central role in the carbon cycle of the boreal landscape. These systems typically stratify in summer and their hypolimnetic microbial communities influence burial of biogenic organic matter in sediments. The composition of bacterial communities in these suboxic habitats was studied by pyrosequencing of 16S rRNA amplicons from ...
Lee Kyu Won - - 2012
Half-metallicity in carbon nanotubes is achieved and controlled by hydrogen adsorption patterns. The edge states in carbon nanotubes are unstable under an electric field due to the spin-conserving electron transfer between the edges, but a large enough transfer barrier between the edge states, obtained by controlling the adsorption patterns, renders ...
Petkov V - - 2012
Water defines life on Earth from the cellular to the terrestrial level. Yet the molecular level arrangement in water is not well understood, posing problems in comprehending its very special chemical, physical and biological properties. Here we present high-resolution x-ray diffraction data for water clearly showing that its molecular arrangement ...
Peng Judy - - 2012
The first EMBL conference on "Omics and Personalized Medicine", jointly organized by Rudi Balling (LCSB, Luxembourg), Leroy Hood, Wolfgang Huber (EMBL, Heidelberg, Germany) and Lars Steinmetz (EMBL) addresses the potential and challenges of translating systems biology research into the clinic. This meeting report provides a highlight of the conference, covering ...
Teunis Pfm - - 2012
The marginal distribution of serum antibody titres in a cross-sectional population sample can be expressed as a function of the infection rate, taking into account heterogeneity in peak levels and decay rates. This marginal model allows estimation of incidences, as well as simple tests for homogeneity across age, gender or ...
Beyer J - - 2012
Effects of a longitudinal magnetic field on optical spin injection and detection in InAs/GaAs quantum dot (QD) structures are investigated by optical orientation spectroscopy. An increase in the optical and spin polarization of the QDs is observed with increasing magnetic field in the range 0-2 T, and is attributed to suppression ...
Sendur Mehmet Ali Nahit - - 2012
Bisphosphonates are the most commonly used agents in the treatment of osteoporosis, and bisphosphonate therapy reduces the risk of skeletally related complications in patients with bone metastases due to malignancy. However, the effect of oral alendronate treatment on clinical and pathological properties of breast cancer has not been reported. Thus, ...
Di Iorio Biagio - - 2012
Background: Hemodialysis patients have a high cardiovascular mortality, and hypertension is the most prevalent treatable risk factor. We aimed to assess the predictive significance of dialysis-to-dialysis variability in blood pressure in hemodialysis patients. Methods: We performed a historical cohort study in 1,088 prevalent hemodialysis patients, followed up for 5 years. ...
Ju Jianfeg - - 2012
In the present study, sequence variations at four nuclear introns which were respectively from the parathyroid hormone-like (PTH) gene, isolate Pdalz1692 interferon (IFN) gene, peripherin-like (RDS) gene, and tyrosine kinase receptor-like (KIT) gene, were examined to analyze genetic diversity and population structure of the finless porpoise (Neophocaena phocaenoides) in Chinese ...
Wang Qiming - - 2012
Dynamic electrostatic lithography is invented to dynamically generate various patterns on large-area and curved polymer surfaces under the control of electrical voltages. The shape of the pattern can be tuned from random creases and craters to aligned creases, craters and lines, and the size of the pattern from millimeters to ...
Magazzini Simone - - 2012
To analyze the clinical characteristics of acute meningitis and their relationship with age in adult patients presenting to the emergency department. We retrospectively investigated consecutive adult patients admitted with a diagnosis of bacterial or viral meningitis from 2002 to 2006. Data about patient's history, symptoms and signs at presentation, etiology ...
Nedjat-Haiem Frances R - - 2012
OBJECTIVE: Previous cancer research does not adequately inform us about the experiences of managing a more serious, life-threatening cancer condition, especially for underserved Latinas. This study was designed to explore the ways in which Latinas navigate through and deal with advanced cancers. METHODS: A purposive sample of 24 underserved Latina ...
Mizuhashi Koji - - 2012
In vertebrate bone formation, the functional mechanisms of transcription factors in osteoblastic differentiation have been relatively well elucidated; however, the exact roles of cell-extrinsic molecules are less clear. We previously identified human and mouse Obif, an osteoblast induction factor, also known as Tmem119, which encodes a single transmembrane protein. OBIF ...
Ginzinger Werner - - 2012
A series of ruthenium(II) arene complexes with 3-(1H-benzimidazol-2-yl)-1H -quinoxalin-2-one, bearing pharmacophoric groups of known protein kinase inhibitors, and related benzoxazole and benzothiazole derivatives have been synthesized. In addition, the corresponding osmium complexes of the unsubstituted ligands have also been prepared. The compounds have been characterized by NMR, UV-vis, and IR ...
Atamna Hani - - 2012
Mitochondrial dysfunction (primary or secondary) is detrimental to intermediary metabolism. Therapeutic strategies to treat/prevent mitochondrial dysfunction could be valuable for managing metabolic and age-related disorders. Here, we review strategies proposed to treat mitochondrial impairment. We then concentrate on redox-active agents, with mild-redox potential, who shuttle electrons among specific cytosolic or ...
Balconi Michela - - 2012
Shared representations, emotion comprehension, and emotion regulation constitute the basic macro components of social empathy. The present study integrated two different measures of empathic behavior in a social context: verbal self-report measures (empathic response, emotional involvement and emotional significance, and valence), and autonomic responses (facial expression-corrugator supercilii and zygomaticus major ...
Gazquez Cristina - - 2012
Study Type - Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Muscle invasive bladder cancer has a mortality rate at 5 years of 50%, despite radical therapy, as a result of tumour progression and dissemination. This suggests that half of patients ...
Lam Judith M JM Clinical Neurorehabilitation, Department of Neurology, University of Zürich and Rehabilitation Initiative and Technology Center of Zürich, Zürich, - - 2013
Learning efficacy depends on its emotional context. The contents learned and the feedback received during training tinges this context. The objective here was to investigate the influence of content and feedback on the efficacy of implicit learning and to explore using functional imaging how these factors are processed in the ...
Lin Nancy U - - 2012
Afatinib is an oral, ErbB family blocker, which covalently binds and irreversibly blocks all kinase-competent ErbB family members. This phase II, open-label, single-arm study explored afatinib activity in human epidermal growth factor receptor 2 (HER2)-positive breast cancer patients progressing after trastuzumab treatment. Patients had stage IIIB/IV HER2-positive metastatic breast cancer, ...
Coia Valentina - - 2012
Although essential for the fine-scale reconstruction of genetic structure, only a few micro-geographic studies have been carried out in European populations. This study analyzes mitochondrial variation (651 bp of the hypervariable region plus 17 single-nucleotide polymorphisms) in 393 samples from nine populations from Trentino (Eastern Italian Alps), a small area characterized ...
Carpenter Michael A - - 2012
The combined structural and antiferromagnetic phase transition in wüstite, Fe(1-x)O, at the Néel temperature, T(N) ∼ 195 K, is treated in terms of coupling between two macroscopic order parameters related to separate discrete instabilities. These each couple with a rhombohedral shear strain to give an indirect mechanism of linear (structural)-quadratic (magnetic) coupling between ...
Moghimi Saba - - 2012
Emotional responses can be induced by external sensory stimuli. For severely disabled nonverbal individuals who have no means of communication, the decoding of emotion may offer insight into an individual's state of mind and his/her response to events taking place in the surrounding environment. Near-infrared spectroscopy (NIRS) provides an opportunity ...
Yeghiazaryan Marine - - 2012
Matrix metalloproteinases (MMPs) are key regulators of extracellular matrix remodeling, but have also important intracellular targets. The purpose of this study was to examine the activity and subcellular localization of the gelatinases MMP-2 and MMP-9 in skeletal muscle of control and physically trained rats. In control hind limb muscle, the ...
Ferland Guylaine - - 2012
Historically discovered for its role in blood coagulation, there is now convincing evidence that vitamin K has important actions in the nervous system. As a unique cofactor to the γ-glutamyl carboxylase enzyme, vitamin K contributes to the biological activation of proteins Gas6 and protein S, ligands for the receptor tyrosine ...
Ribeiro Rosane Aparecida - - 2012
Taurine (Tau) is involved in beta (β)-cell function and insulin action regulation. Here, we verified the possible preventive effect of Tau in high-fat diet (HFD)-induced obesity and glucose intolerance and in the disruption of pancreatic β-cell morpho-physiology. Weaning Swiss mice were distributed into four groups: mice fed on HFD diet ...
Wu Tsung-Han - - 2012
Micro (mi)RNAs are abundant small noncoding RNAs found in plants and animals, the regulatory functions of which are not fully understood in fish. To identify potential miRNAs, we screened an miRNA microarray with total RNA from zebrafish infected with Vibrio harveyi and another from uninfected zebrafish. Six miRNAs were obtained ...
Sugio Mutsumi - - 2012
Enchytraeus japonensis is a small oligochaete that reproduces mainly asexually by fragmentation (autotomy) and regeneration. As sexual reproduction can also be induced, it is a good animal model for the study of both somatic and germline stem cells. To clarify the features of stem cells in regeneration, we investigated the ...
Tarvainen Mika P - - 2012
Heart rate variability (HRV) has been observed to decrease during anesthesia, but changes in HRV during loss and recovery of consciousness have not been studied in detail. In this study, HRV dynamics during low-dose propofol (N = 10) and dexmedetomidine (N = 9) anesthesia were estimated by using time-varying methods. ...
da Cunha Vr - - 2012
Objectives: To evaluate the prevalence of metabolic syndrome (MetS) in patients with rheumatoid arthritis (RA) vs. controls, and to verify possible associations of MetS with specific disease-related factors. Methods: The subjects were 283 RA patients and 226 healthy controls, frequency matched by age and sex. MetS was defined according to ...
Ardalan Mohammadreza - - 2012
Sarcoidosis is a systemic disorder with a wide spectrum of clinical involvements. Renal mass is a very rare condition in sarcoidosis. Here, we report a 34-year-old female with renal masses and advanced renal failure. The condition created a lot of diagnosis difficulties. Finally, after histologic diagnosis and corticosteroid therapy, renal ...
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