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Parhami Iman I UCLA Gambling Studies, Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA. - - 2013
The purpose of this study is to investigate the relationship between sleep disturbances and gambling behavior. Data from the National Comorbidity Survey-Replication (NCS-R) was used to examine the relationship between three specific sleep complaints (difficulty initiating sleep [DIS], difficulty maintaining sleep [DMS], and early morning awakening [EMA]) and gambling behavior. ...
Ashitate Yoshitomo Y Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, - - 2013
Methylene blue (MB) is a near-infrared fluorophore that provides a stable visual map of skin perfusion after intravenous injection. We explored the capability of MB to predict submental flap postoperative outcome using a single intraoperative measurement. Submental flaps were created in N = 15 pigs and imaged using the FLARE ...
Ramlal Roshan T RT University of North Carolina, Chapel Hill, NC, USA. - - 2013
We describe change in weight, midupper arm circumference (MUAC), arm muscle area (AMA) and arm fat area (AFA) in 1130 pregnant HIV-infected women with CD4 counts > 200 as part of the BAN Study ( www.thebanstudy.org ), a randomized, controlled clinical trial to evaluate antiretroviral and nutrition interventions to reduce mother-to-child transmission ...
Papiţa Ana Maria - - 2012
HIV infected patients have an increased cardiovascular risk that may be linked not only to the infection itself but also to the metabolic side effects of the antiretroviral therapy. The aim of our study was to determine markers of aortic arterial stiffness, carotid intima-media thickness (IMT) and parameters of left ...
Ayaz Umit Yasar - - 2012
We report the initial and follow-up ultrasonography (US) findings in a pediatric case of wandering spleen with symptoms of acute abdomen, as a rare entity. A four-year-old boy was referred with complaints of blunt abdominal pain, vomiting and fatigue. US detected an oval- shaped, mildly enlarged spleen with inferomedial displacement. ...
Homorodean Călin - - 2012
In order to conduct research relying on ultrasound images, it is necessary to access a large number of relevant cases represented by images and their interpretation. DICOM standard defines the structured reporting information object. Templates are tree-like structures which offer structural guidance in report construction. Laying the foundations of a ...
Yildirim Duzgun - - 2012
Lipomas are benign mesenchymal tumors, which accounts for 50% of soft tissue tumors. Although the etiopathogenesis has not yet been fully understood, it is known that lipomas developed at a rate of 1% in the related localizations after traumas. Trauma initiates inflammatory reactions in fatty tissue and these can be ...
Gliga Mirela - - 2012
We present the case of a woman with known risk factors for embolism with multiple kidney infarctions. She was admitted with left renal colic, discrete hematuria and subfebrility. She was under acenocumarolum treatment but without efficient anticoagulation. Ultrasound performed at the emergency room revealed smaller right kidney (congenital hypoplasia) and ...
Gruber Hannes - - 2012
The currently accepted pathophysiological concept behind median arcuate ligament syndrome (MALS) is vascular compromise by atypically positioned median arcuate ligament. Despite many articles on MALS, only sparse data on the outcome in general and the rather poor outcome after intervention have been reported and this makes at least questionable the ...
Ozel Alper - - 2012
The purpose of this study was to define the criteria for use in differentiating benign and malignant nodules with the help of the receiver operating characteristic analysis and to increase the objective diagnostic accuracy of ultrasonography. A total of 363 patients (307 women, 56 men) with 363 nodules (22 malignant ...
Micu Mihaela C - - 2012
In the last years musculoskeletal ultrasound (US) has become a very useful imaging tool for the evaluation of rheumatic patients and a natural extension of the clinical examination of the ankle and foot. Musculoskeletal US allows the evaluation of the symptomatic and asymptomatic ankle and foot with a detailed analysis ...
Tankova Ludmila Tanova - - 2012
To assess the changes in the angiogenic status of rectal cancer before and after preoperative radiotherapy (RT) using endosonography (ES). Fifty-four patients with rectal cancer were examined by ES before and 6-7 weeks after preoperative RT and . The tumour size, stage, echostructure and vascularization before and after RT were ...
Pop Sorin - - 2012
The incidence of agenesis of inferior vena cava in the general population was estimated at 0.6 - 0.8%. In patients with deep vein thrombosis the frequency of agenesis was estimated between 5 and 6.7% in young people. In this pictorial essay, we present the ultrasound findings obtained in 8 patients ...
Popov Horatiu I - - 2012
Milwaukee shoulder syndrome (MSS) describes a destructive shoulder arthropathy associated with of calcium hydroxyapatite and calcium pyrophosphate dihydrate crystals deposition found mainly in elderly women. Pigmented villonodular synovitis (PVNS) is a benign proliferative disorder of the synovium usually seen in young adults, found frequently in the knee joint. We present ...
Perciun Rodica - - 2012
Insulin treatment can lead to local soft tissue dystrophies. We present the cases of two insulin-treated subjects with two different injecting systems: a basal/bolus and a continuous subcutaneous insulin infusion (insulin pump). The local cutaneous/subcutaneous dystrophies adversely affected their glycaemic values. A conventional and a high resolution ultrasound (20MHz Dermascan) ...
Heinrich A - - 2012
This study was undertaken to characterize the ATP, adenosine and glutamate outflow evoked by depolarization with high K(+) concentrations, in slices of rat hippocampus. We utilized the microelectrode biosensor technique and extracellular electrophysiological recording for the real-time monitoring of the efflux of ATP, adenosine and glutamate. ATP, adenosine and glutamate ...
Schaufler Candi - - 2012
The aim of the present study was to review postoperative complications of pediatric patients undergoing colectomy for ulcerative colitis (UC) or inflammatory bowel disease-unspecified (IBD-U) with a focus on preoperative immunosuppression including exposure to infliximab. We performed a retrospective chart review of all of the children with UC or IBD-U ...
Tanyi Miklós - - 2012
Lynch syndrome (Hereditary nonpolyposis colorectal cancer, HNPCC) is an inherited disease with variable phenotype causing the development of colon cancer and other malignancies. The basis of the disease is believed to be the mismatch repair gene mutations. Genetic screening has been performed among the patients who have undergone surgery for ...
Brozek Izabela - - 2012
It is estimated that about 5-10% of ovarian and 2-5% of all breast cancer patients are carriers of a germline BRCA1 or BRCA2 gene mutation. Most families with detected BRCA1 or BRCA2 gene mutation are qualified for molecular testing on the basis of family history of breast or ovarian cancers. ...
Yu Lei - - 2012
Rosiglitazone is an anti-diabetic drug acting as an insulin sensitizer. We recently found that rosiglitazone also inhibits the vascular isoform of ATP-sensitive K(+) channels and compromises vasodilatory effects of β-adrenoceptor activation and pinacidil. As its potency for the channel inhibition is in the micromolar range, rosiglitazone may be used as ...
Fujii Hirohito - - 2012
5-HT is taken up by and stored in adrenergic nerves and periarterial nerve stimulation (PNS) releases 5-HT to cause vasoconstriction in rat mesenteric arteries. The present study investigated whether PNS-released 5-HT stored in adrenergic nerves affects the function of perivascular calcitonin gene-related peptide-containing (CGRPergic) nerves. Rat mesenteric vascular beds without ...
Gandhi A S - - 2012
Gene expression of Cyp3a11 is reduced by activation of Toll-like receptors (TLRs) by Gram-negative or Gram-positive bacterial components, LPS or lipoteichoic acid (LTA) respectively. The primary adaptor protein in the TLR signalling pathway, TIRAP, plays differential roles in LPS- and LTA-mediated down-regulations of Cyp3a11 mRNA. Here, we have determined the ...
Phimsen Suchada - - 2012
Cancer cells often contain p53 abnormalities that impair cell-cycle checkpoint progression and cause resistance to various anti-cancer treatments. DNA damage occurs at actively transcribed genes during G1-phase in yeast cells that have a deficient mRNA export capacity. Here, we show that germinal center-associated nuclear protein (GANP), a homologue of yeast ...
Barreiro-de Acosta Manuel - - 2012
In refractory pouchitis, infliximab (IFX) has been used as rescue therapy; however, there is no clinical evidence for the use of adalimumab (ADA). The aim of this study was to report the efficacy of ADA in patients with refractory pouchitis previously treated with IFX. A retrospective, open-label, case series was ...
Lew Michael J - - 2012
Statistical analysis is universally used in the interpretation of the results of basic biomedical research, being expected by referees and readers alike. Its role in helping researchers to make reliable inference from their work and its contribution to the scientific process cannot be doubted, but can be improved. There is ...
Wimmer Markus A - - 2012
Surface damage of the tibial polyethylene insert in TKA is thought to diminish with increasing conformity, based on computed lower contact stresses. Added constraint from higher conformity may, however, result in greater forces in vivo. We therefore determined whether increased conformity was associated with increased surface pitting, delamination, creep, and ...
Chen Min - - 2012
To investigate reversal effects of pantoprazole (PPZ) on multidrug resistance (MDR) in human gastric adenocarcinoma cells in vivo and in vitro. Human gastric adenocarcinoma cell SGC7901 was cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum and antibiotics in a humidified 5% CO(2) atmosphere at 37°C. Adriamycin (ADR)-resistant cells ...
Doulgeraki Artemis - - 2012
Bone tissue is adversely affected in patients with homozygous β-thalassemia. The aim of this study was to find warning signs of bone loss in young patients with β-thalassemia and allow prompt therapeutic interventions. Thirty-eight patients were studied, 20 boys and 18 girls, aged 5 to 18 years (median = 14.13 ...
Li Andrew - - 2012
The majority of the cases of nephroblastoma do not present with abdominal pain. We present a patient with an acute surgical abdomen due to perforated appendicitis and an incidental abdominal mass. He underwent an urgent appendectomy after which tumor specific therapy was successfully initiated.
Lehman Dara A DA Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, - - 2012
Resistance commonly arises in infants exposed to single-dose nevirapine (sdNVP) for prevention of mother to child transmission. Although K103N and Y181C are common following sdNVP, multiple other mutations also confer NVP resistance. It remains unclear whether specific NVP resistance mutations or combinations of mutations predict virologic failure in infants when ...
Helenius I Taneli IT Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts 02129, - - 2012
The number of possible small organic molecules of different structure is virtually limitless. One of the main goals of chemical biologists is to identify, from this "chemical space", entities that affect biological processes or systems in a specific manner. This can lead to a better understanding of the regulation and ...
Ghosh Sudipta S Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, VIC 3002, - - 2012
  To determine the prevalence of signs and symptoms of ocular surface disease in two hospital-based cohorts; glaucoma patients and non-glaucoma patients.   A cross-sectional, comparative case series.   Glaucoma patients (n = 300) prescribed topical glaucoma medications for ≥6 months were compared with control patients (n = 100) who were not applying prescribed topical ...
Voogd J - - 2012
The definition of Purkinje cell zones by their white matter compartments, their physiological properties, and their molecular identity and the birthdate of their Purkinje cells will be reviewed.
Mosam Anisa - - 2012
The optimal approach to HIV-associated Kaposi sarcoma (HIV-KS) in sub-Saharan Africa is unknown. With large-scale rollout of highly active antiretroviral therapy (HAART) in South Africa, we hypothesized that survival in HIV-KS would improve and administration of chemotherapy in addition to HAART would be feasible and improve KS-specific outcomes. We conducted ...
Sunyer J Oriol - - 2012
The evolutionary origins of Ig-producing B cells appear to be linked to the emergence of fish in this planet. There are three major classes of living fish species, which from most primitive to modern they are referred to as agnathan (e.g., lampreys), Chondrichthyes (e.g., sharks), and teleost fish (e.g., rainbow ...
Bradshaw David H - - 2012
We propose a theoretical framework for the behavioral modulation of pain based on constructivism, positing that task engagement, such as listening for errors in a musical passage, can establish a construction of reality that effectively replaces pain as a competing construction. Graded engagement produces graded reductions in pain as indicated ...
Gebauer Gregory - - 2012
Strict criteria have been used before removing cervical collars in patients with injuries who have midline pain or are unable to be reliably examined. This sometimes leads to prolonged immobilization in cervical collars or use of MRI to rule out injury. Several studies suggest a collar may be removed in ...
Sayde William M - - 2012
Superior labral anterior-posterior (SLAP) lesions are a common cause of pain and disability in athletes. Individual studies have suggested low patient satisfaction with SLAP repairs in throwing athletes in particular and it is unclear how frequently athletes return to their previous level of competetion. We systematically reviewed the literature to ...
Li Yan - - 2012
xCT is the functional subunit of the cystine/glutamate antiporter system xc-, which exchanges intracellular glutamate with extracellular cystine. xCT has been reported to play roles in the maintenance of intracellular redox and ambient extracellular glutamate, which may affect neuronal function. To assess a potential role of xCT in the mouse ...
Litton Jennifer K - - 2012
The increased availability of assisted reproductive technologies (ART) allows women with fertility issues to increase their chances of a successful pregnancy with the use of medications that, in some cases, increase circulating estrogens. There has been significant concern that the use of these medications will increase the risk of hormone-sensitive ...
Deng Jiusheng - - 2012
B cells play a pivotal role in host adaptive immunity against pathogenic microorganisms, but may also maladaptively contribute to the pathogenesis of autoimmune diseases. In contrast, distinct B cell subsets have the capacity to regulate host immune response, and suppress inflammation. B regulatory cells are a rare population of endogenous ...
Head M W MW National CJD Research & Surveillance Unit, School of Molecular & Clinical Medicine, University of Edinburgh, Edinburgh, UK. - - 2012
The human transmissible spongiform encephalopathies or human prion diseases are one of the most intensively investigated groups of rare human neurodegenerative conditions. They are generally held to be unique in terms of their complex epidemiology and phenotypic variability, but they may also serve as a paradigm with which other more ...
Barr Tom A TA Institute of Immunology and Infection Research, University of Edinburgh, Ashworth Laboratories, King's Buildings, West Mains Road, Edinburgh, EH9 3JT, UK. - - 2012
B cells are once again gaining prominence as important programmers of CD4 T cell responses. With widespread use of B cell depletion therapy in the clinic, proving effective in treating diseases previously considered T cell-mediated, the time is right for a re-appraisal of the B cell. Though typically considered weak, ...
Hermans Sabine M SM Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda. - - 2012
The World Health Organization recommends that treatment of tuberculosis (TB) in HIV-infected patients should be integrated with HIV care. In December 2008, a separate outdoor-integrated TB/HIV clinic was instituted for attendees of a large urban HIV clinic in Uganda. We sought to evaluate associated TB and HIV treatment outcomes. Routinely ...
Vajro Pietro - - 2012
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in children and adolescents in the United States, and most probably also in the rest of the industrialized world.As the prevalence of NAFLD in childhood increases with the worldwide obesity epidemic, there is an urgent need ...
Johnson Christopher K - - 2012
Biventricular pacing (BiVP) improves cardiac output (CO) and mean arterial pressure (MAP) after cardiopulmonary bypass (CPB) in selected patients at risk for acute left heart failure after cardiac surgery. Optimization of atrioventricular delay (AVD) and interventricular delay (VVD) to maximize the hemodynamic effect of pacing requires rapid and accurate data ...
Keeley Patrick W - - 2012
Wild-type mouse retina immunofluorescently labeled to reveal the populations of melanopsin-positive ganglion cells (green) and dopaminergic amacrine cells (magenta). Each cell type shows abnormal clustering and fasciculation in both Dscam- and Bax- deficient mice, though the profile of these features is distinct in the two mutants. The Journal of Comparative ...
Brenner Lawrence H - - 2012
The term "standard of care" has been used in law and medicine to determine whether medical care is negligent. However, the precise meaning of this concept is often unclear for both medical and legal professionals. Our purposes are to (1) examine the limitations of using standard of care as a ...
Amoako Kagya A - - 2012
Intravascular catheters used in clinical practice can activate platelets, leading to thrombus formation and stagnation of blood flow. Nitric oxide (NO)-releasing polymers have been shown previously to reduce clot formation on a number of blood contacting devices. In this work, trilaminar NO-releasing silicone catheters were fabricated and tested for their ...
Parker Charles J CJ Division of Hematology and Hematologic Malignancies, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA. - - 2012
The aim is to report on recent observations related to the natural history of paroxysmal nocturnal hemoglobinuria (PNH) and to review new therapeutic strategies for controlling the hemolysis of PNH. This review focuses on studies designed to characterize the long-term outcome of patients with PNH treated with eculizumab and to ...
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