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Afanetti Mickael - - 2012
Afanetti M, Niaudet P, Niel O, Saint Faust M, Cochat P, Berard E. Pediatric en bloc kidney transplantation into pediatric recipients: The French experience. Pediatr Transplantation 2012: 16: 183-186. © 2012 John Wiley & Sons A/S. Abstract:  Chronic shortage of available donor organs has led to re-evaluation of the use ...
Al-Bader Tamara - - 2012
Background  The pathophysiology of cellulite involves changes in the subcutaneous adipose layer and the extracellular matrix (ECM) that supports it together with overlying dermal layer. Cellular mechanisms governing cellulite are not fully understood. However, it is accepted that changes include enhanced lipogenesis, decreased lipolysis, and increased lipid storage within the ...
Naidoo Shan - - 2012
A brief overview of the Green Paper on the National Health Insurance (NHI) policy of South Africa is presented. It describes the intention of the NHI to ensure equity, address the inequalities presented by the current private and public health system and present an ambitious plan to change the face ...
Bielanska Joanna - - 2012
Because Kv1.3 and Kv1.5 K(+) channels are remodeled during tumorigenesis and participate in skeletal muscle proliferation, we analyzed their expression in human skeletal muscle sarcomas. Aggressive alveolar rhabdomyosarcoma (ARMS) and embryonal rhabdomyosarcoma (ERMS) were studied. Kv1.5 expression was moderate in adult muscle and low in ERMS, whereas it was notable ...
Miller Allison - - 2012
In long-lived, clonally reproducing species, assessing organism size is a nontrivial endeavour because each genetically distinct entity (genet) may comprise multiple modular units (ramets). Attributes of clonally reproducing populations, such as genet size, longevity and clonal diversity (the number of genets in a population), have significant implications for the persistence ...
Polefka Thomas G - - 2012
The earliest known microfossil records suggest that microorganisms existed on the earth approximately 3.8 billion years ago. Not only did sunlight drive this evolutionary process, but it also allowed photosynthetic organisms to elaborate oxygen and fundamentally change the earth's atmosphere and subsequent evolution. Paradoxically, however, an atmosphere of 20% oxygen ...
Ko Jae Sung - - 2012
Ko JS, Yi N-J, Suh KS, Seo JK. Pediatric liver transplantation for fibropolycystic liver disease. Pediatr Transplantation 2012: 16: 195-200. © 2012 John Wiley & Sons A/S. Abstract:  Fibropolycystic liver disease includes CHF, Caroli's syndrome, and Caroli's disease. Patients with Caroli's disease and Caroli's syndrome have an increased risk of ...
Cortijo E - - 2012
AIM. To study the frequency, safety and efficacy of perfusion computed tomography (PCT), through identification of brain tissue-at-risk, to guide intravenous thrombolysis in stroke patients with regulatory exclusion criteria (SITS-MOST and ECASS-3). PATIENTS AND METHODS. We studied consecutive acute non-lacunar ischemic stroke patients. After conventional CT was considered eligible, PCT ...
Goodwin Jonathan M - - 2012
Herpes-mediated viral oncolysis alone is not sufficient to completely eradicate tumors. In this study we used a replication conditional, endostatin-expressing herpes simplex virus-1 mutant (HSV-Endo) in a murine lung cancer model. We hypothesized that the anti-angiogenic action of endostatin would improve upon the oncolytic effect of HSV-1. HSV-Endo was evaluated ...
Amburgey James E - - 2012
Cryptosporidium has caused the majority of waterborne disease outbreaks in treated recreational water venues in the USA for many years running. This research project evaluated some common US swimming pool filters for removing Cryptosporidium oocysts, 5-µm diameter polystyrene microspheres, and 1-µm diameter polystyrene microspheres. A 946 L hot tub with ...
Beach Renée A - - 2012
Objective  To investigate changes in sebum cytokines in response to hair cosmetics. Design and setting  A prospective study at a University hospital. Methods  We used a novel method for scalp surface sebum collection (Sebutape(®) ) on three visits, sequentially a week apart, to investigate changes in six cytokines in 36 ...
Chapman M Shane - - 2012
Vitamin A is required for the proper functioning of many important metabolic and physiologic activities, including vision, gene transcription, the immune system and skin cell differentiation. Both excessive and deficient levels of vitamin A lead to poor functioning of many human systems. The biologically active form, retinoic acid, binds to ...
Naselli Angelo - - 2012
The present technique maintains the integrity of voluminous lesions during extraction. Pathological analysis is consequently improved and a proper evaluation of the surgical margins is also possible. Papillary lesions of up to 4.5 cm are amenable to en bloc resection and extraction, while solid lesions comply less well with the ...
Rodríguez S - - 2012
Campylobacter is a major waterborne pathogen that can be found in rivers of the Mediterranean area. Characteristics of these rivers change throughout the seasons due to variations in environmental parameters. As these variations may affect water survival of Campylobacter, we analyzed it in the Llobregat River using three approaches whose ...
Kramer Marlene - - 2012
The objective of the study was to examine effects of nurse-confirmed healthy unit work environments and multistage nurse residency programs (NRPs) on retention rates of newly licensed RNs (NLRNs). Establishing a culture of retention and healthy clinical nurse practice environments are two major challenges confronting nurse leaders today. Nurse residency ...
Creer Simon - - 2012
Deep sea environments cover more than 65% of the earth's surface and fulfil a range of ecosystem functions, yet they are also amongst the least known habitats on earth. Whilst the discovery of key geological processes, combined with technological developments, has focused interest onto geologically active areas such as hydrothermal ...
Anunciato Talita Pizza - - 2012
The market for cosmeceuticals continues with significant annual growth, but today consumers are more aware of nutritional products that contribute to both skin health and disease prevention. In the last 10 years, pharmacists, chemists, nutritionists, and physicians have been working together to develop new nutritional applications to satisfy people's needs and ...
Cheriaa Jihane - - 2012
The purpose of the present study was to explore the potential behavioural changes of Pseudomonas aeruginosa following growth in different aquatic environmental conditions. To achieve this, P. aeruginosa was cultured in various water microcosms for 12 months under fixed (pH, nutrients and temperature) factors. P. aeruginosa responses to these conditions ...
Morton Laurel M - - 2012
The management of acute and chronic wounds has drastically changed within the past 20 years. This update focuses on the most recent recommendations for acute wound care as well as new technologies that are available for chronic wounds.
Berger Jill T - - 2012
A large healthcare system was challenged to develop a nursing professional practice model that would apply to and be understood by nurses at all levels and across all entities of the organization. A team was convened, composed of direct care nurses, educators, clinical nurse specialists, Magnet program directors, managers, and ...
Maunula Leena - - 2012
Norovirus (NoV) is one of the most common causative agents of waterborne gastroenteritis outbreaks. The main objective of the study was to determine the presence of human NoVs in river water and in treated wastewater (TW) released into the river. During a one-year survey in 2007/2008, NoVs were detected in ...
Sobhi Rehab Mohamed - - 2012
Background  Melasma is a common pigmentary disorder. Despite the availability of a wide range of skin-lightening treatments, melasma of skin remains a therapeutic challenge. Objective  The aim of this study was to evaluate the efficacy and safety of nanosome vitamin C iontophoresis and to compare the therapeutic effects of nanosome ...
Meng Na - - 2012
Seventeen patients with head and neck recurrent carcinoma underwent (125)I seed implantation under CT or ultrasound guidance. The actuarial D90 of the (125)I seeds implanted was 90-160 Gy (median, 126 Gy). Median follow-up was 10 months (range, 3-48 months). The median local control time was 16 months; the 1- and ...
Humbert Philippe - - 2012
As time passes, wrinkles typically appear. These skin depressions that become deeper and deeper draw more and more coarser lines on almost all the visible parts of aging individual's skin. They are indeed the most obvious and maybe disliked signs of skin aging, and thus, preventing and treating them are ...
Mora-Simon S - - 2012
INTRODUCTION. Along past years, interest in mild cognitive impairment (MCI) research and its early detection has been increased. Unlike first theories, international current proposals suggest that MCI is a syndrome characterized by an impairment in one or more cognitive functions without interfering in daily functional abilities and it is also ...
Samaras Loukas - - 2012
Recent research has shown the potential of Web queries as a source for syndromic surveillance, and existing studies show that these queries can be used as a basis for estimation and prediction of the development of a syndromic disease, such as influenza, using log linear (logit) statistical models. Two alternative ...
McCann Laura - - 2012
This paper presents qualitative findings from a larger sequential mixed methods study which sought to provide an in-depth understanding of pharmacist prescribing from the perspective of pharmacist prescribers, medical colleagues and key stakeholders in Northern Ireland. Transcriptions were analyzed using thematic analysis as the interviews progressed and emergent themes were ...
Berkow Steven - - 2012
Frontline nurses are foundational to any organizational goal concerning patient care. In addition, healthcare delivery reform has supported the formalization of specific goals that hospitals must advance to stay financially viable and to deliver high-quality care. As a result, goals for frontline staff are continuously evolving. Frontline nurses must demonstrate ...
Collins Fiona - - 2012
Transformation in the structure and delivery of services for children and young people in the UK Children Act (Department for Education & Skills, 2004. The Children Act. London: HMSO) initiated new alliances between statutory, public and voluntary agencies. Traditional relationships and notions of partnership have been extended, necessitating an innovative ...
Sporing Eileen - - 2012
The nursing career lattice program (NCLP) at Children's Hospital Boston has provided employees with social, educational, and financial assistance as they begin or advance their nursing careers. At the conclusion of a pilot phase, 35% of employees in the NCLP were enrolled in nursing school and 15% completed nursing school. ...
Niyyati Maryam - - 2012
A survey was conducted to determine the presence of free-living amoebae (FLA), especially Acanthamoeba and Naegleria, in river recreation areas in Tehran Province, Iran. All rivers surveyed were associated with human activity, and two were also a source of municipal tap water. Fifty-five water samples from 10 major rivers were ...
O'Donnell Allison T - - 2012
The incidence of melanoma is on the rise, and early detection of disease is imperative to reduce mortality. Dermatologists are key players in the early detection of melanoma; however, some clinicians rely on their clinical examination without any additional diagnostic tools to make this important diagnosis. Certain patients, such as ...
Krathen Michael - - 2012
The detection of cutaneous melanoma still largely relies on clinical suspicion, skin biopsy, and histopathologic evaluation. New technologies are being evaluated to bypass the skin biopsy in the detection of melanoma. The quest for reliable biomarkers, with respect to subclinical detection, prognosis, and predicting treatment response, is longstanding and ongoing. ...
Riess Jonathan W - - 2012
We retrospectively analyzed hematologic parameters in 22 patients with advanced, nonsquamous, NSCLC undergoing VEGF inhibition on a phase II clinical trial of bevacizumab, carboplatin, and gemcitabine. We also examined TTP in relation to hemoglobin changes. Median hemoglobin increased significantly from a 12.9 g/dL pretreatment to 13.8 g/dL (p =.01) after ...
Coelho Tracy - - 2012
Immunosuppression after organ transplantation is complex and ever evolving. Over the past two decades, newer immunosuppressive agents have been introduced with an aim to provide better patient and graft survival. Improved therapeutic strategies have been developed offering the option to use combinations of drugs with non-overlapping toxicities. There are, however, ...
Berardesca Enzo - - 2012
  Rosacea is a chronic inflammatory skin disease affecting mostly facial skin. Its origin is multifactorial. Important steps in its treatment are avoidance of any triggering factor and control of skin inflammation.   To assess the benefit of topical applications of a new product (P-3075).   A randomized, multicenter, double-blind, ...
Pham Betty - - 2012
NK cells are important in the immune response against tumors and virally infected cells. A balance between inhibitory and activating receptors controls the effector functions of NK cells. We examined the fate of circulating NK cells and the expression of the NK cell-activating receptors in pediatric liver transplant recipients. Blood ...
Poligone Brian - - 2012
In the management of patients with cutaneous T-cell lymphoma (CTCL), there are numerous distinct therapy options. Each of these therapies is discussed in terms of when to use it, what factors limit the success of the treatment, and what to expect. A menu is defined as a list of items ...
Harrison Joyce Nolan - - 2012
The Food and Drug Administration has approved the use of antipsychotic medications in some children and adolescents with severe emotional and behavioral disorders. However, recent national data show a dramatic rise in off-label and Food and Drug Administration-approved uses of these medications. Of particular note is a twofold to fivefold ...
Kindermann Ingrid - - 2012
Myocarditis is an inflammatory disease of the heart frequently resulting from viral infections and/or post-viral immune-mediated responses. It is one of the important causes of dilated cardiomyopathy worldwide. The diagnosis is presumed on clinical presentation and noninvasive diagnostic methods such as cardiovascular magnetic resonance imaging. Endomyocardial biopsy remains the gold ...
Oba Toyoharu - - 2012
The study investigated the role of myocardial suppressor of cytokine signaling-3 (SOCS3), an intrinsic negative feedback regulator of the janus kinase and signal transducer and activator of transcription (JAK-STAT) signaling pathway, in the development of left ventricular (LV) remodeling after acute myocardial infarction (AMI). LV remodeling after AMI results in ...
Vollmann Dirk - - 2012
The purpose of this study was to evaluate the prevalence and mechanism of a misleading long post-pacing interval (PPI) upon entrainment of typical atrial flutter (AFL) from the cavotricuspid isthmus (CTI). In typical AFL, the PPI from entrainment at the CTI is expected to closely match the tachycardia cycle-length (TCL). ...
Gerber Bernhard L - - 2012
The purpose of this study was to evaluate the impact of myocardial viability assessment by delayed-enhanced cardiac magnetic resonance (DE-CMR) and of revascularization therapy on survival in patients with coronary artery disease (CAD) and low ejection fraction (EF). Prior studies have shown that DE-CMR predicts recovery of left ventricular (LV) ...
Zellweger Michael J - - 2012
This study sought to define the importance of 5-year coronary artery disease (CAD) progression after successful stenting. Safety concerns regarding first-generation drug-eluting stents mandate 5-year follow-up studies. However, only limited data exist on the long-term importance of CAD progression relative to late stent-related problems. This study followed for 5 years, ...
Eleid Mackram F - - 2012
The goal of this study was to determine the impact of transvenous pacemaker and defibrillator leads on the incidence of bioprosthetic tricuspid valve (BTV) regurgitation compared with BTV patients without a transvalvular lead. Although concern has been raised regarding the potential deleterious effect of permanent transvenous device leads on BTV ...
Hirsch Glenn A - - 2012
This study tested the hypothesis that acute administration of the xanthine oxidase (XO) inhibitor allopurinol improves cardiac high-energy phosphate concentrations in human heart failure (HF) and increases the rate of adenosine triphosphate (ATP) synthesis through creatine kinase (CK), the primary myocardial energy reserve. Studies of patients and animal models implicate ...
Jansen Vincent A A - - 2012
de Jager et al. (Reports, 24 June 2011, p. 1551) concluded that mussels Lévy walk. We confronted a larger model set with these data and found that mussels do not Lévy walk: Their movement is best described by a composite Brownian walk. This shows how model selection based on an ...
de Mel Suresh - - 2012
Standard economic theory suggests that one-time business grants can have at most temporary effects, and accordingly, policies to increase incomes of the self-employed in developing countries typically rely on sustained engagement. In contrast, we found long-lasting impacts from one-time grants given in a randomized experiment to subsistence firms. Five years ...
Wyllie David J A - - 2012
A single amino acid residue determines single-channel conductance, ion permeation and channel block in the NMDA receptor, three of the key features of this ligand-gated ion channel.
Medina-Elizalde Martín - - 2012
The disintegration of the Classic Maya civilization in the Yucatán Peninsula and Central America was a complex process that occurred over an approximately 200-year interval and involved a catastrophic depopulation of the region. Although it is well established that the civilization collapse coincided with widespread episodes of drought, their nature ...
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