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Results 701 - 750 of 1428
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Wuerger Sophie M - - 2012
Biological motion is usually associated with highly correlated sensory signals from more than one modality: an approaching human walker will not only have a visual representation, namely an increase in the retinal size of the walker's image, but also a synchronous auditory signal since the walker's footsteps will grow louder. ...
Thanikaivelan Palanisamy - - 2012
A stable magnetic nanocomposite of collagen and superparamagnetic iron oxide nanoparticles (SPIONs) is prepared by a simple process utilizing protein wastes from leather industry. Molecular interaction between helical collagen fibers and spherical SPIONs is proven through calorimetric, microscopic and spectroscopic techniques. This nanocomposite exhibited selective oil absorption and magnetic tracking ...
Ten Dijke Peter - - 2012
Endothelial-to-mesenchymal transition (EndoMT) is an instrumental step in the development of valves in the embryonic heart. This process is driven by activation of transforming growth factor-β (TGF-β) signaling and is characterized by the loss of endothelial and gain of mesenchymal phenotype, and by delamination of cells from the surface into ...
Hingorjo Mozaffer Rahim - - 2012
To evaluate the usefulness of neck circumference as an index of excess weight and obesity in young adults while identifying its appropriate cutoff points. The study comprised 41 male and 109 female students, aged 18-20 years. Anthropometric markers of obesity were measured, including body mass index, waist circumference, hip circumference, ...
Min Kyung-Jin - - 2012
To validate the efficacy of Seeplex HPV4A ACE for the detection of high-risk (HR) human papillomavirus (HPV) and HPV 16 and/or HPV 18 genotypes as compared to the PCR method and the Cervista HPV assays in cervical swab samples. Besides liquid-based cytology, additional 97 cervical swab samples were collected for ...
Petronella Pasquale - - 2012
It presents a clinical case of undifferentiated retroperitoneal liposarcoma with 5 years' recurrence from the first operation for the rarity of the occurrence, the problems related to surgery and complementary therapeutic approach. Male patient aged 73 was operated for removal of retroperitoneal mass with involvement of the right kidney at ...
Schmitt Deanna M DM Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of - - 2012
Vaccination is a proven strategy to mitigate morbidity and mortality of infectious diseases. The methodology of identifying and testing new vaccine candidates could be improved with rational design and in vitro testing prior to animal experimentation. The tularemia vaccine, Francisella tularensis live vaccine strain (LVS), does not elicit complete protection ...
Hancock Timothy - - 2012
In this paper we investigate how metabolic network structure affects any coordination between transcript and metabolite profiles. To achieve this goal we conduct two complementary analyses focused on the metabolic response to stress. First, we investigate the general size of any relationship between metabolic network gene expression and metabolite profiles. ...
Lotto Lorella - - 2012
People have fought for their civil rights, primarily the right to live in dignity. At present, the development of technology in medicine and healthcare led to an apparent paradox: many people are fighting for the right to die. This study was aimed at testing whether different moral principles are associated ...
Sehlin Dag - - 2012
Soluble amyloid-β (Aβ) aggregates of various sizes, ranging from dimers to large protofibrils, have been associated with neurotoxicity and synaptic dysfunction in Alzheimer's Disease (AD). To investigate the properties of biologically relevant Aβ species, brain extracts from amyloid β protein precursor (AβPP) transgenic mice and AD patients as well as ...
Weyers Jill J - - 2012
Visualization of the vasculature is becoming increasingly important for understanding many different disease states. While several techniques exist for imaging vasculature, few are able to visualize the vascular network as a whole while extending to a resolution that includes the smaller vessels. Additionally, many vascular casting techniques destroy the surrounding ...
Matteini Paolo - - 2012
We report recent achievements and future perspectives of minimally invasive bonding of biological tissues triggered by laser light. In particular, we review new advancements in the biomedical exploitation of near-infrared absorbing gold nanoparticles as an original solution for the photothermal closure of surgical incisions. Advanced concepts of laser tissue bonding ...
Kacprzak Michal - - 2012
Recent studies have shown that time-resolved optical measurements of the head can estimate changes in the absorption coefficient with depth discrimination. Thus, changes in tissue oxygenation, which are specific to intracranial tissues, can be assessed using this advanced technique, and this method allows us to avoid the influence of changes ...
Yuen Clement - - 2012
Hemozoin is a by-product of malaria infection in erythrocytes, which has been explored as a biomarker for early malaria diagnosis. We report magnetic field-enriched surface-enhanced resonance Raman spectroscopy (SERRS) of β-hematin crystals, which are the equivalent of hemozoin biocrystals in spectroscopic features, by using magnetic nanoparticles with iron oxide core ...
Qureshi F - - 2012
A case report and literature review of a unique presentation of metastatic breast cancer is provided. A 46-year-old patient with a history of breast carcinoma presented with a choroidal mass. Three days later she went on to develop bilateral simultaneous orbital cellulitis, investigation of which revealed underlying bony metastases from ...
Tian Sun - - 2012
Furin cleaves diverse types of protein precursors in the secretory pathway. The substrates for furin cleavage possess a specific 20-residue recognition sequence motif. In this report, based on the functional characterisation of the 20-residue sequence motif, we developed a furin cleavage site prediction tool, PiTou, using a hybrid method composed ...
Nakamura Yasuko - - 2012
We herein present a case of 6-year-old female demonstrating atypical Ramsay-Hunt syndrome. She presented with an earache, severe vertigo, and vomiting at onset, and thereafter, herpes zoster oticus appeared. No facial nerve palsy was seen. She was vaccinated for varicella and had no past history of apparent varicella infection. The ...
Amir Derakhshanfar - - 2012
To evaluate the frequency of complications in Laparoscopic cholecystectomies performed in Hamadan during 1997 to 2005. In this retrospective cross sectional study, 426 patients with cholecystitis who were admitted to Hamadan hospitals including Ekbatan, Tamin Ejtamaiee, Mobasher, Boali and Artesh and were subjected to laparoscopic cholecystectomy from 1997 to 2005 ...
Jargin Sergei V - - 2012
In a large series of studies was reported that culturing of smooth muscle cells with serum from atherosclerosis patients caused intracellular lipid accumulation, while serum from healthy controls had no such effect. Cultures were used for evaluation of antiatherogenic drugs. Numerous substances were reported to lower serum atherogenicity: statins, trapidil, ...
Hou Yu-Chih - - 2012
To determine the phenotype-genotype correlations in patients with corneal dystrophies associated with human transforming growth factor-β-induced (TGFBI) mutations at the National Taiwan University Hospital. Twenty-five affected patients from 15 families with corneal dystrophies were recruited. They underwent slit-lamp biomicroscopy and visual acuity examinations. Genomic DNA was extracted from their peripheral ...
Lataillade Max - - 2012
It is unknown whether HIV-positive patients experiencing virologic failure (VF) on boosted-PI (PI/r) regimens without drug resistant mutations (DRM) by standard genotyping harbor low-level PI resistant variants. CASTLE compared the efficacy of atazanavir/ritonavir (ATV/r) with lopinavir/ritonavir (LPV/r), each in combination with TVD in ARV-naïve subjects. To determine if VF on ...
Maurer Lisa M LM Departments of Biomolecular Chemistry and Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of - - 2012
Picomolar concentrations of proteins comprising only the N-terminal 70-kDa region (70K) of fibronectin (FN) stimulate cell migration into collagen gels. The Ile-Gly-Asp (IGD) motifs in four of the nine FN type 1 (FNI) modules in 70K are important for such migratory stimulating activity. The 70K region mediates binding of nanomolar ...
de Vries Marieke - - 2012
In mammalian male gametogenesis the sex chromosomes are distinctive in both gene activity and epigenetic strategy. At first meiotic prophase the heteromorphic X and Y chromosomes are placed in a separate chromatin domain called the XY body. In this process, X,Y chromatin becomes highly phosphorylated at S139 of H2AX leading ...
Singh Prashant Kumar - - 2012
Coupled with the largest number of maternal deaths, adolescent pregnancy in India has received paramount importance due to early age at marriage and low contraceptive use. The factors associated with the utilization of maternal healthcare services among married adolescents in rural India are poorly discussed. Using the data from third ...
Ribeiro Cecilia Claudia Costa - - 2012
No consensus exists regarding the need for a second clinical session to remove carious dentin that remains in the pulp wall after partial caries removal. The purpose of the present article was to review studies that evaluated the effect of partial caries removal as provisional or definitive treatment on the ...
Saeed Muhammad Usman - - 2012
Purpose: To report posterior capsular opacification in acrylic intraocular lenses. Methods: Retrospective review of notes of patients with cataract surgery involving implantation of a hydrophilic acrylic intraocular lens (IOL) (MDR SC-60B-0UV) in at least one eye. This was done as a retrospective audit for clinical risk following adverse event reports, ...
Hirata Tetsuya - - 2012
The generation of induced pluripotent stem cells (iPSCs) by the forced expression of defined transcription factors in somatic cells holds great promise for the future of regenerative medicine. However, the initial reprogramming mechanism is still poorly understood. Here we show that Zscan4, expressed transiently in2-cell embryos and embryonic stem cells ...
Carleo Giuseppe - - 2012
When classical systems fail to explore their entire configurational space, intriguing macroscopic phenomena like aging and glass formation may emerge. Also closed quanto-mechanical systems may stop wandering freely around the whole Hilbert space, even if they are initially prepared into a macroscopically large combination of eigenstates. Here, we report numerical ...
Nunberg Jack H JH Montana Biotechnology Center, The University of Montana, Missoula, MT 59812, USA. - - 2012
Arenaviruses comprise a diverse family of enveloped negative-strand RNA viruses that are endemic to specific rodent hosts worldwide. Several arenaviruses cause severe hemorrhagic fevers in humans, including Junín and Machupo viruses in South America and Lassa fever virus in western Africa. Arenavirus entry into the host cell is mediated by ...
Salvà Antoni - - 2012
To estimate the number of fallers and risk factors for falls in a cohort with dementia, we did a secondary analysis of a cluster-randomized controlled trial (NutriAlz) in 11 outpatient and day care centers in Catalonia (Spain) including 626 community-dwelling patients with dementia, followed for 12 months. Participants' characteristics were ...
Kim Sunduk - - 2012
The purpose of this study was to assess the risk of ingestion exposure of lead by particle sizes of crumb rubber in artificial turf filling material with consideration of bioavailability. This study estimated the ingestion exposure by particle sizes (more than 250 um or less than 250 um) focusing on ...
Mishin Igor - - 2012
Vermiform appendix torsion is rare, and even more uncommon is the volvulus of appendiceal mucinous tumors. To our knowledge, only nine cases of torsion of the vermiform appendix associated with appendiceal mucinous neoplasms have been reported up to date. We report a case of secondary torsion of the vermiform appendix ...
De Franceschi Lucia L Department of Medicine, University of Verona, Verona, Italy. - - 2012
Acanthocytes, abnormal thorny red blood cells (RBC), are one of the biological hallmarks of neuroacanthocytosis syndromes (NA), a group of rare hereditary neurodegenerative disorders. Since RBCs are easily accessible, the study of acanthocytes in NA may provide insights into potential mechanisms of neurodegeneration. Previous studies have shown that changes in ...
Zhang Xuan - - 2012
Hepatitis B virus X protein (HBx) plays an important role in the development of hepatocellular carcinoma (HCC). However, the mechanism remains unclear. Recently, we have reported that HBx promotes hepatoma cell migration through the upregulation of calpain small subunit 1 (Capn4). In addition, several reports have revealed that osteopontin (OPN) ...
Sahlander Karin - - 2012
Pig farmers are exposed to organic material in pig barns on a daily basis and have signs of an ongoing chronic airway inflammation and increased prevalence of chronic inflammatory airway diseases, predominantly chronic bronchitis. Interestingly, the inflammatory response to acute exposure to organic dust is attenuated in farmers. The aim ...
Kang Dongyel D University of Arizona, College of Optical Sciences, 1630 East University Boulevard, Tucson, Arizona 85721, USA. - - 2012
We theoretically investigate the effect of noise on frequency-domain heterodyne and/or homodyne measurements of intensity-modulated beams propagating through diffusive media, such as a photon density wave. We assumed that the attenuated amplitude and delayed phase are estimated by taking the Fourier transform of the noisy, modulated output data. We show ...
Werner Stephanie L - - 2012
The purpose of this study was to investigate dental caries and body mass index (BMI percentile) in pediatric dental patients. A 3-year retrospective review of patient records included all 6- to 9-year-olds seen for a new patient examination who had at least 1 recall examination. Decayed permanent teeth (DT) and ...
Lugo J E - - 2012
The fulcrum principle establishes that a subthreshold excitatory signal (entering in one sense) that is synchronous with a facilitation signal (entering in a different sense) can be increased (up to a resonant-like level) and then decreased by the energy and frequency content of the facilitating signal. As a result, the ...
Tanaka Gouhei - - 2012
Many social, biological, and technological networks consist of a small number of highly connected components (hubs) and a very large number of loosely connected components (low-degree nodes). It has been commonly recognized that such heterogeneously connected networks are extremely vulnerable to the failure of hubs in terms of structural robustness ...
Sun Yang - - 2012
The threat of a new influenza pandemic has existed since 1997, when the highly pathogenic H5N1 strain of avian influenza A virus infected humans in Hong Kong and spread across Asia, where it continued to infect poultry and people. The human mortality rate of H5N1 infection is about 60%, whereas ...
Kumada Tomohiro - - 2012
The ketogenic diet (KD) is a high-fat, low-protein, low-carbohydrate diet which is effective in the treatment of medically refractory epilepsy. Several theories have been proposed to explain the mechanism underlying the anticonvulsant efficacy of the KD, however, the precise anticonvulsant mechanism of the KD is still unknown. We speculated the ...
Iynen Ismail - - 2012
To investigate the effects of extracorporeal shockwave lithotripsy on hearing. The study group consisted of 34 patients with urinary lithiasis on whom ESWL was applied in a single course. Patients with normal hearing levels were included in the study. Conventional audiometry and transient evoked otoacoustic emissions were recorded before the ...
Prestigiacomo Jennifer - - 2012
At a recent gathering healthcare industry leaders and public officials discuss the best governance models that will be necessary to ensure the long-term viability of health information exchanges.
Zhang Guodong - - 2012
To investigate the development and mineralization of avian scleral ossicles using fluorescence microscopy in combination with field emission scanning electron microscopy (FESEM) and energy dispersive spectroscopy (EDS). The anterior halves of whole eyeballs from chickens on embryonic (E) days E10 to E21 and Japanese quail on embryonic days E8 to ...
Chuang Shen-Fung - - 2012
The protozoan Giardia lamblia differentiates from a pathogenic trophozoite into an infectious cyst to survive outside of the host. During encystation, genes encoding cyst wall proteins (CWPs) are coordinately induced. Pax family transcription factors are involved in a variety of developmental processes in animals. Nine Pax proteins have been found ...
Smith Benjamin J - - 2012
Mice with a function-blocking mutation in the Scn8a gene that encodes Na(v)1.6, a voltage-gated sodium channel (VGSC) isoform normally found in several types of retinal neurons, have previously been found to display a profoundly abnormal dark adapted flash electroretinogram. However the retinal function of these mice in light adapted conditions ...
de Paula Alcio Coutinho - - 2012
Background: To determine the alterations in the corneal topography after pars planavitrectomy with the system of 20- and 25-gauge. Methods: A total of 29 patients with vitreous hemorrhage. The first group (17 patients) had to undergo a pars planavitrectomy with the 20-gauge system, whereas the second (12 patients) had the ...
Roth Melissa S - - 2012
Climate change driven increases in intensity and frequency of both hot and cold extreme events contribute to coral reef decline by causing widespread coral bleaching and mortality. Here, we show that hot and cold temperature changes cause distinct physiological responses on different time scales in reef-building corals. We exposed the ...
Tarr Alexander W - - 2012
Infection with Hepatitis C Virus (HCV) causes chronic disease in approximately 80% of cases, resulting in chronic inflammation and cirrhosis. Current treatments are not completely effective, and a vaccine has yet to be developed. Spontaneous resolution of infection is associated with effective host adaptive immunity to HCV, including production of ...
Wirostko Barbara M - - 2012
To assess the ocular effects and safety profile of chronic sildenafil oral dosing in patients with pulmonary arterial hypertension. 12 week, double masked, randomised, placebo controlled, phase III trial with open label extension. 53 institutions worldwide. 277 adults with idiopathic pulmonary arterial hypertension or pulmonary arterial hypertension associated with connective ...
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