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Aneja Savina - - 2012
To determine whether there is an association between dermatologist density and melanoma mortality. A regression model was developed to test the association between melanoma mortality and dermatologist density, controlling for county demographics, health care infrastructure, and socioeconomic factors. Data were collected from the Area Resource File, US Centers for Disease ...
McCarty Statham Melissa - - 2012
(1) To determine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization in children undergoing open airway surgery using a screening protocol; (2) to examine the rates of postoperative infection in this cohort; and (3) to determine adherence to a MRSA antibiotic protocol. Retrospective cohort study. Tertiary pediatric referral center. The ...
Lee I-Te - - 2012
In this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, bitter gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects ...
Pellai A - - 2012
Considering how eating habits affect the health of children and taking into account the influence of advertising messages, we wanted to investigate the quantity and the typology of advertising on air during children's television programmes. The research was conducted beginning in January 2008 up to March 2008. During this period ...
Wang Wen-Guang - - 2012
Tupaia belangeri are small mammals with a squirrel-like appearance; they were formerly classified under the primates order despite the lack of derived features characteristic of primates. Given that T. belangeri are easy to raise, cheap to maintain, and have a small body size, a high reproductive rate, and close affinity ...
Meyer A-K - - 2012
One third of the population above 70 has a diabetic-like metabolic status. Diabetes-induced diseases as well as acute blood sugar imbalances have great impact on quality of life. Transferring the known disease management regimes from adults to the elderly is only possible to a limited extent. For patients needing short-term ...
Naydov I A - - 2012
The dye H2DCF-DA, which forms the fluorescent molecule DCF in the reaction with hydrogen peroxide, H2O2, was used to study light-induced H2O2 production in isolated intact chloroplasts and in protoplasts of mesophyll cells of Arabidopsis, pea, and maize. A technique to follow the kinetics of light-induced H2O2 production in the ...
Lerner Thomas R - - 2012
Bdellovibrio are predatory bacteria that have evolved to invade virtually all Gram-negative bacteria, including many prominent pathogens. Upon invasion, prey bacteria become rounded up into an osmotically stable niche for the Bdellovibrio, preventing further superinfection and allowing Bdellovibrio to replicate inside without competition, killing the prey bacterium and degrading its ...
Kandil Emad - - 2012
To describe a robotic technique for transaxillary gasless thyroidectomy with the addition of intraoperative peripheral nerve monitoring in the surgical management of thyroid disease. Prospective study. Academic institution. Fifty patients underwent robotic transaxillary thyroidectomy from September 1, 2009, to August 31, 2010. All the patients underwent preoperative and postoperative direct ...
Wu Xu-Jun - - 2012
We showed that rhesus monkeys (Macaca mulatta) can develop a morphine dependence. Rhesus monkeys successfully established a conditioned place preference (CPP) induced by morphine treatment and this preference lasted for at least (36.3±1.3) months. This animal model may be useful for research into addiction in humans.
Tempelhof S - - 2012
Osteopathic medicine is a healing modality applied with the doctor's two hands that is similar to but goes far beyond the Manual medicine/chirotherapy which is well known in Germany. Founded in 1874 by Dr. A.T. Still in Kirksville, Missouri in the USA, osteopathic medicine is in addition to the M.D. ...
Zhu Lin - - 2012
Nonhuman primates are critical resources for biomedical research. Rhesus macaque is a popularly used laboratory nonhuman primate that share many characteristics with humans. However, rhesus macaques are the natural host of two exogenous retroviruses, SRV (simian type D retrovirus) and STLV (simian T lymphotropic virus). SRV and STLV may introduce ...
Rizkalla Reilly N - - 2012
Celiac disease is an underdiagnosed condition in children with variable manifestations. Presenting symptoms in children are changing over time, are impacted by age and geography, and are distinct from those of adults with this disease. Prompt diagnosis of celiac disease in affected children may avoid growth and nutritional deficits in ...
Weil S - - 2012
Epilepsy is a common neurological condition with gender-related management implications. Epilepsy and antiepileptic drug treatment affect aspects of contraception, fertility and pregnancy which are discussed in the article.
Balaban N P - - 2012
In this review the main families of endopeptidases belonging to the clan of metzincins of zinc-dependent metalloproteinases in organisms of wide evolutional range from bacteria to mammals are considered. The data on classification, physicochemical properties, substrate specificity, and structural features of this group of enzymes are given. The activation mechanisms ...
Bátorfi József - - 2012
Introduction: The occult inguinal hernia in athletes represents a distinct entity as well as a part of a syndrome known as PIPS (public inguinal pain syndrome). It may be relatively difficult to identify the possible source of inguinal pain, since the spectrum is so wide that it can overlap various ...
Di Filippo T - - 2012
Creativity represents the silent character of human behaviour. In children with epilepsy, cognitive performance of has mainly been investigated under the assumption that the disorder represents a risk factor for the development of intellectual function. In subjects with different forms of epilepsy, neuropsychologic disorders have been detected even when cognitive-global ...
Simm A - - 2012
The incidence of diabetes has increased in the recent years. Diabetes is characterized by increased sugar concentrations in the blood. Due to this dysregulation, more carbohydrate-induced modification of proteins - so-called advanced glycation end products (AGEs) - are formed endogenously by non-enzymatic reactions. These are discussed to be at least ...
Lomonosova Yu N - - 2012
Gravitational unloading causes atrophy of muscle fibers and can lead to destruction of cytoskeletal and contractile proteins. Along with the atrophic changes, unloaded muscle frequently demonstrates significant shifts in the ratio of muscle fibers expressing fast and slow myosin heavy chain isoforms. Stretching of the m. soleus during hindlimb suspension ...
Ji Fang - - 2012
To explore pathological alteration of T2DM in cynomolgus monkeys, gene expression profiles of peripheral blood leukocytes from spontaneous and diet-induced T2DM models was analyzed using quantitative real-time PCR. Among 36 T2DM associated genes tested, 19 genes (including G6PC, CCR2B, CTLA4) displayed a similar expression pattern in both spontaneous and diet-induced ...
Wu Genfu - - 2012
Iron-sulfur cluster is one of the most common prosthetic groups, and it functions in numerous biological processes. However, little is currently known about the mechanisms of iron-sulfur cluster biosynthesis. In this study, we cloned and purified iron-sulfur cluster assembly proteins from Escherichia coli and assembled the cluster in vitro. The ...
Aarts Mark C J - - 2012
Guidelines may assist physicians and patients in decisions about effective and safe care. Little is known about the awareness of, opinions about, and adherence to evidence-based guidelines in otolaryngology. We performed a survey among 440 otorhinolaryngologists of the Dutch Society of Otolaryngology-Head and Neck Surgery. The questionnaire consisted of questions ...
Meisel M - - 2012
The standard geriatric basic assessment validly presents the functional limitations of elderly patients. The prognosis estimation of elderly people is less precise using the instruments for cardiovascular and preoperative risk evaluation or by the intensive care medicine scores on organ failure. An adaptation and further development of score systems could ...
Steinau H U - - 2012
Adequate surgical removal of soft tissue sarcomas of the trunk and extremities employing safety margins of 1-2 cm is the accepted basis of multidisciplinary treatment. In cases of high risk tumors (grades G2/G3) the tumor board decision should include radiochemotherapy under study conditions. Difficult peripheral locations or perioperative complications require additional ...
Elalfy Mohsen S - - 2012
Infants between 6 and 24 months of age are at the highest risk of development of iron deficiency anemia (IDA) in developing countries. Consuming unmodified cow's milk, delayed introduction of solid foods after 6 months, and high birth order could be predictors of the presence of IDA. Three hundred infants ...
Lin Jing-Yi - - 2012
Replication of plus-stranded RNA viruses is greatly affected by numerous host-coded proteins acting either as susceptibility or resistance factors. Previous genome-wide screens and global proteomics approaches with Tomato bushy stunt tombusvirus (TBSV) in a yeast model host revealed the involvement of cyclophilins, which are a large family of host prolyl ...
Garonzik-Wang Jacqueline M - - 2012
The ability to predict outcomes following a kidney transplant is limited by the complex physiologic decline of kidney failure, a latent factor that is difficult to capture using conventional comorbidity assessment. The frailty phenotype is a recently described inflammatory state of increased vulnerability to stressors resulting from decreased physiologic reserve ...
Bian Hui - - 2012
To investigate a simple and effective intraocular xenotransplant technique of rhesus monkey neural progenitor cells to rats, mechanical injury was induced in the rat's right retina. And the GFP-labeled rhesus monkey neural progenitor cells suspension was slowly injected into the vitreous space of the right injured and left control eye. ...
Segerstrom Suzanne C - - 2012
The concept of stress has a long and perhaps foundational history in health psychology. However, it is also not without its detractors, who point out imprecise and simplistic use of the concept. Four challenges for stress research in health psychology delineate the nuanced and contextualised future. First, 'stress' can be ...
Dong Jin-Run - - 2012
To investigate the characteristics of rhesus monkey embryonic stem cells and to promote their clinical application, the differentiation and proliferation of rosettes neural stem cells from GFP marked rhesus monkey embryonic stem cells were studied The results showed that: 1) A stable and high-efficient neural differentiation system was established. More ...
Parisi L - - 2012
Hypomelanosis of Ito (HOI) is a multisystem neurocutaneous disorder. In the described cases, cutaneous manifestations (unilateral or bilateral streaks and swirls of hypomelanosis with regular and confluent borders) and extracutaneous abnormalities are often associated. Extracutaneous abnormalities involve the musculoskeletal system (scoliosis, vertebral anomalies, cranial-facial malformations) and other organs, as well ...
Noachtar S - - 2012
Advances in diagnostic and therapeutic options require a revision of the current classification of seizures and epilepsies. Recently, a classification proposal was introduced which reflects the ambivalence of the Internationalen Liga gegen Epilepsie (ILAE). We suggest that epileptology should utilize the same established systematic approach used in clinical neurology.
Gekeler F - - 2012
Stimulation with weak electrical currents as a potential therapy for ophthalmic diseases has been propagated for a long time and encountered mixed acceptance but has recently regained interest due to observations in retinal implant projects. In these projects involving patients with retinitis pigmentosa a neuroprotective effect of weak, even subthreshold, ...
Armin Bob B - - 2012
To assess clinical and radiologic findings from targeted radiotherapy to the rat maxilla and to compare findings with a recently developed rat model of mandibular osteoradionecrosis (ORN). A prospective, controlled animal study. Ten male Sprague-Dawley rats were divided into an experimental group receiving catheter-assisted high-dose-rate brachytherapy (n = 6) and a control ...
Choi Sae Byeol - - 2012
Most morbidity and mortality are caused by a pancreatic fistula after pancreaticoduodenectomy (PD), and its prevention is the major concern. We applied the omental roll-up technique around pancreaticojejunostomy and investigated the effectiveness of this technique to prevent a pancreatic fistula. Retrospective study. Tertiary hepatobiliary and pancreas surgery clinic, Korea University ...
Choi Hanui - - 2012
The traditional Asian diet, which is characterized as being high in carbohydrate with an abundance of vegetables, may be beneficial for preventing metabolic syndrome abnormalities within the Asian population. However, the prevalence of metabolic syndrome is increasing in Asian countries. This study explored the association between dietary carbohydrates and low ...
Soanes Darren M - - 2012
The rice blast fungus Magnaporthe oryzae is one of the most significant pathogens affecting global food security. To cause rice blast disease the fungus elaborates a specialised infection structure called an appressorium. Here, we report genome wide transcriptional profile analysis of appressorium development using next generation sequencing (NGS). We performed ...
Li Ming-Li - - 2012
Interferons (IFNs) represent proteins with antiviral activities that are secreted from cells in response to a variety of stimuli. In addition to antiviral, antibacterial and anti-parasitic host-defense functions they are now also recognized as crucial regulators of cell proliferation, differentiation, survival and death as well as activators of specialized cell ...
Werber A - - 2012
Poor efficiency in terms of treatment of unspecific back pain and related chronic pain syndromes has led to the necessity of general care guidelines addressing evidence-based strategies for treatment of lower back pain (LBP). Systematically validated and reviewed algorithms have been established for all kinds of unspecific back pain, covering ...
Webber Naomi K - - 2012
Lichen planus (LP) is a mucocutaneous inflammatory disease that affects multiple sites, including the skin, oral cavity, vulva, and vagina and can result in scarring and stricture formation. It has also been shown to cause lacrimal canalicular blockage in a series of patients attending an ophthalmology clinic. We describe a ...
Dell'era L - - 2012
Systemic lupus erythematosus (SLE) has been reported to be associated to Wilson's disease, as a complication of treatment with penicillamine. Even though drug-induced lupus erythematosus (DILE) has some features in common with SLE, they are distinct entities. We report the case of a young girl who at the age of ...
Wang Jing - - 2012
Depression is a common neuropsychiatric disorder, marked by depressed mood for at least two weeks. The World Health Organization predicts that depression will be the number one leading cause of disease and injury burden by 2030. Clinical treatment faces at least three serious obstacles. First, the disease mechanism is not ...
Lehner G F - - 2012
Monitoring of organ function is one of the core tasks of intensive care medicine. Although various monitoring devices and parameters have already been established for some organs, there are no or only few conditionally useful parameters or scores available for the kidneys, liver, gastrointestinal tract, and blood coagulation. Therefore, specific ...
Rupp S - - 2012
Total knee replacement (TKR) is a highly standardized procedure. However; many patients are not satisfied with the functional results. Surgery focuses initially on restoration of joint function. Based on the ICF classification (WHO) rehabilitation adds individual and social perspectives. The focus is not limited to body functions but includes abilities ...
Kerl Katrin - - 2012
BACKGROUND: Transepidermal melanocytic migration (TEM) is an important diagnostic criterion for malignancy, especially in association with cytologic atypia. However, TEM may also be observed in benign melanocytic tumors, such as Spitz nevus, acral nevi, or nevi in infancy. We discuss the value of TEM for the diagnosis of melanocytic tumors ...
Werhahn K J - - 2012
Epilepsies frequently only start in old age and given the current demographic trend the prevalence of epilepsy in the elderly population will increase. This article summarizes the most relevant aspects of diagnosis and therapy in elderly patients with epilepsy. Guidelines, systematic reviews or meta-analyses are lacking and there are only ...
Szentmáry N - - 2012
Photodynamic therapy (PDT) has been used in ophthalmology for the last 10 years particularly for disorders of the posterior pole. In recent years PDT has been increasingly applied for corneal cross-linking in progressive keratoconus. The classical PDT is performed with porphyrins as photosensitizers and illumination with visible light of 630-635 nm ...
Osler Turner - - 2012
Complications are common in the care of trauma patients and contribute to morbidity, mortality, and cost. However, no comprehensive list of surgical complications is widely accepted. To create an empirical list of complications based on the International Classification of Diseases, Ninth Revision (ICD-9) lexicon and estimate the contribution of these ...
Kong Ling-An - - 2012
Chitin is a major component of fungal cell wall and is synthesized by chitin synthases (Chs). Plant pathogenic fungi normally have multiple chitin synthase genes. To determine their roles in development and pathogenesis, we functionally characterized all seven CHS genes in Magnaporthe oryzae. Three of them, CHS1, CHS6, and CHS7, ...
Umar Sanusi - - 2012
BACKGROUND: The large caliber of head hair in hair transplantation imparts a coarse hairline, whereas natural hairlines are typically softer. In hirsute individuals, transplantation of leg hair to the hairline may result in a superior aesthetic appearance. Observation  A total of 1025 leg hair follicles in 1 patient were grafted ...
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