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Jonsson T B - - 2012
Trials have reported clinical improvement and reduced need for amputation in critical limb ischemia (CLI) patients receiving therapeutic angiogenesis with stem cells. Our objective was to test peripheral stem cell therapy efficacy and safety to gain experiences for further work. We included nine CLI patients (mean age 76.7 ±9.7). Stem ...
Jones Julie M - - 2012
Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a type III hypersensitivity reaction characterized by urticaria with persistent acquired hypocomplementemia. Although HUVS is uncommon, it is important for physicians to be familiar with this disease, as the initial presentation is often life-threatening angioedema. The author reports the case of a 47-year-old white ...
Guyatt Gordon H - - 2012
The Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines differs substantially from the prior versions both in process and in content. In this introduction, we describe some of the differences and the rationale for the changes.
Gross Charles - - 2012
Presents an obituary for Bartley Gore Hoebel; 1935-2011. Bart pioneered in the measurement of neurochemical release in local brain sites of freely moving animals. Bart's early research was on the role of the ventromedial and lateral regions of the hypothalamus in the control of eating and satiety. Later he expanded ...
Gouveia Valdiney V - - 2012
The General Health Questionnaire (GHQ-12) detects non severe psychiatric illnesses. Although commonly treated as a general index, the definition of its factorial structure is cause for debate. This study aimed to test this structure comparing three models: two frequently cited in the literature (one- and bi- factorial) and a third, ...
Loeffler David A DA Department of Neurology Research, William Beaumont Hospital, Royal Oak, Michigan, USA. - - 2012
Intravenous immunoglobulin (IvIg) preparations consist of purified human immunoglobulins collected from large numbers of healthy persons and are used to treat autoimmune, immunodeficiency, and inflammatory disorders. Studying the effects of IvIg effects in experimental animal models might clarify its mechanisms of action in these disorders, but whether 'serum sickness' or ...
Pokorny Joel - - 2012
Previous studies of color matching found that Grassmann's laws are not obeyed in the short-wavelength region when the method of maximum saturation matching is compared with Maxwell matching. The first experiment evaluated whether the discrepancy might be due to a discrimination matching range asymmetry around either the saturated or desaturated ...
Gerçekcioğlu Hamza - - 2012
Results obtained on the intensity fluctuations of flat-topped Gaussian beams in weakly turbulent non-Kolmogorov horizontal atmospheric optics links are represented. Effects on the scintillation index of the power law α that describes the non-Kolmogorov spectrum are examined. Our results correctly reduce to the existing intensity fluctuations of flat-topped beams in ...
Meltzer Eli O - - 2012
People with allergic rhinitis rate their overall health significantly lower than individuals without nasal allergies.
Guyatt Gordon H - - 2012
This article provides the rationale for the approach to making recommendations primarily used in four articles of the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines: orthopedic surgery, nonorthopedic surgery, nonsurgical patients, and stroke. Some of the early clinical trials of ...
Kaufmann A - - 2012
Patients with congenital and acquired neurogenic bladder dysfunction due to central and peripheral nervous lesions are significantly limited in their daily lives. The neurogenic dysfunction of the bladder and lower urinary tract are often misinterpreted and later fed to a diagnosis. Without therapy severe complications, including renal damage, could be the ...
Shah Sanket U - - 2012
To evaluate the efficacy of topical interferon alfa-2b in the management of ocular surface squamous neoplasia (OSSN). Clinically visible OSSN in 20 patients (23 tumors) was managed with topical interferon alfa-2b, 1 million IU/mL, 4 times daily. Tumor control and complications were evaluated according to American Joint Committee on Cancer ...
- - 2012
▾Fingolimod (Gilenya - Novartis) is a new treatment for patients with highly active relapsing-remitting multiple sclerosis. It is the first oral disease-modifying drug for the treatment of patients with multiple sclerosis. Here we assess the place of this drug.
Wick Jeannette Y - - 2012
Noroviruses are a major cause of acute gastroenteritis affecting people of all ages. Humans are believed to be the sole norovirus host. Among the very young, the very old, and people who are immunocompromised, norovirus infection can be severe and lifeendangering. Of special concern for pharmacists in long-term care facilities, ...
Volbrecht Vicki J - - 2012
Hue-scaling data were collected from three observers using the "4+1" color-naming procedure for circular (0.25°-5°), monochromatic (440-660 nm) stimuli. Stimuli were presented at ±10° along the vertical and horizontal meridians under conditions chosen to include both rod and cone signals (no bleach) and to minimize rod contribution (bleach). All color-naming ...
Hadley James A - - 2012
Allergic rhinitis is rarely found in isolation and should be considered in the context of upper and lower airway disease.
Guyatt Gordon H - - 2012
To develop the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: ACCP Evidence-Based Clinical Practice Guidelines (AT9), the American College of Chest Physicians (ACCP) assembled a panel of clinical experts, information scientists, decision scientists, and systematic review and guideline methodologists. Clinical areas were designated as articles, and a methodologist without ...
Murdaugh Donna L DL Department of Psychology, University of Alabama at Birmingham, Birmingham, AL 35294-1170, USA. - - 2012
Behavioral studies have suggested that food cues have stronger motivating effects in obese than in normal-weight individuals, which may be a risk factor underlying obesity. Previous cross-sectional neuroimaging studies have suggested that this difference is mediated by increased reactivity to food cues in parts of the reward system in obese ...
Lancellotti Patrizio - - 2012
The annual meeting of the European Association of Echocardiography (EuroEcho and other Imaging Modalities) was held in Budapest, Hungary. In the present paper, we present a summary of the 'Highlights' session.
Parry Neil R A - - 2012
Certain hues undergo shifts in their appearance when they are viewed by the peripheral retina. This has often been shown on a 3-primary color CRT monitor. To investigate the possible role of metamerism, we replicated our peripheral color matching experiments using Munsell paper stimuli viewed under real and simulated daylight ...
Kahn Susan R - - 2012
This guideline addressed VTE prevention in hospitalized medical patients, outpatients with cancer, the chronically immobilized, long-distance travelers, and those with asymptomatic thrombophilia. This guideline follows methods described in Methodology for the Development of Antithrombotic Therapy and Prevention of Thrombosis Guidelines: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College ...
Eikelboom John W - - 2012
The article describes the mechanisms of action, pharmacokinetics, and pharmacodynamics of aspirin, dipyridamole, cilostazol, the thienopyridines, and the glycoprotein IIb/IIIa antagonists. The relationships among dose, efficacy, and safety are discussed along with a mechanistic overview of results of randomized clinical trials. The article does not provide specific management recommendations but ...
Havla Joachim B - - 2012
The oral sphingosine-1-phosphate receptor modulator fingolimod (FTY720) was recently approved for the treatment of relapsing-remitting multiple sclerosis. To date, data about a possible recurrence of disease activity after discontinuation of fingolimod treatment are scarce. To describe a patient who discontinued fingolimod treatment after a local malignant melanoma was diagnosed. Three ...
Linhares João Manuel Maciel - - 2012
We propose a chromatic diversity index based on the Munsell set capable of predicting illuminant induced changes in chromatic diversity of complex scenes. The color differences between complex scenes derived from hyperspectral data under a test and under a reference CIE D65 illuminant were computed and compared with the corresponding ...
Guy Bianchi P - - 2012
The aim of this preliminary study is to evaluate the feasibility and efficacy of CAS as treatment option to endarterectomy when carotid shunt cannot be used safely. The medical records concerning 469 carotid stenosis treated between January 2006 and December 2009 were retrospectively reviewed, focusing on cross-clamp intolerance during CEA. ...
Whittaker S - - 2012
Reasons for performing study: Although low birthweight is a risk factor for neonatal illness, the impact of high birthweight on the health of foals and mares, and on the foals' long-term athletic capability, is unknown. Objectives: To investigate whether: 1) foals that are excessively heavy are associated with an increased ...
Fowden A L - - 2012
In adapting to life ex utero, the foal encounters a number of physiological challenges. It has to assume the nutritional, respiratory and excretory functions of the placenta and activate full regulatory control over its own internal environment for the first time. To achieve this, there must be structural and functional ...
Frazão Paulo - - 2012
The cost-effectiveness of a modified supervised toothbrushing program was compared to a conventional program. A total of 284 five-year-old children presenting at least one permanent molar with emerged/sound occlusal surface participated. In the control group, oral health education and dental plaque dying followed by toothbrushing with fluoride dentifrice was carried ...
Mizokami Yoko - - 2012
We examined whether the perception of the colorfulness of an image is influenced by the adaptation of the visual system to natural and shuffled images with different degrees of saturation. In the experiment, observers first became adapted to several images with different levels of saturation and then their colorfulness perception ...
Garcia David A DA University of New Mexico, MSC07-4025, Albuquerque, NM 87131, USA. - - 2012
This article describes the pharmacology of approved parenteral anticoagulants. These include the indirect anticoagulants, unfractionated heparin (UFH), low-molecular-weight heparins (LMWHs), fondaparinux, and danaparoid, as well as the direct thrombin inhibitors hirudin, bivalirudin, and argatroban. UFH is a heterogeneous mixture of glycosaminoglycans that bind to antithrombin via a unique pentasaccharide sequence ...
Morichika Juri - - 2012
At our research center, cynomolgus monkeys (Macaca fascicularis) are bred by mating or intracytoplasmic sperm injection (ICSI) and embryo transfer. We typically transfer 2 embryos, because the pregnancy rate is better than that for single embryo transfer. In the case we present here, 2 embryos that had been frozen and ...
Viénot Françoise - - 2012
Any stimulus can be described as composed of two components-a fundamental color stimulus that controls the three cone responses and a metameric black that has no effect on cones but can drive photoreceptors other than cones [e.g., rods and melanopsin expressing retinal ganglion cells (ipRGCs)]. The Cohen and Kappauf [Am. ...
Whitlock Richard P - - 2012
Antithrombotic therapy in valvular disease is important to mitigate thromboembolism, but the hemorrhagic risk imposed must be considered. The methods of this guideline follow those described in Methodology for the Development of Antithrombotic Therapy and Prevention of Thrombosis Guidelines. Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of ...
Santos Filho José Cândido S - - 2012
In J. Opt. Soc. Am. A27, 797 (2010), Yura and Hanson derived what they claim to be "a general expression for the mean level crossing rate for an arbitrary" random process following any desired probability distribution function. On the other hand, the authors themselves assert that in some cases their ...
Abraham Mary Elizabeth - - 2012
Warfarin is an oral anticoagulant for treatment and prevention of venous and arterial thromboembolism. It requires regular monitoring and patient adherence to a variety of lifestyle factors that can influence its effect. Dabigatran is an oral direct thrombin-inhibitor recently approved for stroke prevention in atrial fibrillation. The primary advantages of ...
Desilets Alicia R - - 2012
To investigate current concerns regarding the use of proton-pump inhibitors (PPIs) in older adults. A literature search was conducted in MEDLINE (1948 to April week 3 2011) to identify relevant publications. Key words searched included proton-pump inhibitor, safety, adverse events, elderly, and older adults. Additional data sources were obtained through ...
Fromer Leonard M - - 2012
Although intranasal steroid sprays are the preferred treatment of the majority of health care providers, this opinion is not carried through to patient treatment.
Weitz Jeffrey I - - 2012
This article focuses on new antithrombotic drugs that are in or are entering phase 3 clinical testing. Development of these new agents was prompted by the limitations of existing antiplatelet, anticoagulant, or fibrinolytic drugs. Addressing these unmet needs, this article (1) outlines the rationale for development of new antithrombotic agents; ...
Krettek C - - 2012
Since the earliest beginnings of using X-rays, two forms of examination techniques have been known: X-ray imaging and projection onto films. The new technology very rapidly became widespread. Just a few months after the discovery of the so-called X-rays, the first fluoroscopes (instruments for visualizing internal structures) were constructed and ...
Gonçalves-Silva Regina Maria Veras - - 2012
Low-cost alternatives that allow for the monitoring of population groups are important strategies in conducting cohort studies. This paper presents the procedures for the use of the National School Census as a search tool for children and adolescents in follow-up studies. The study was conducted among adolescent students who took ...
Goodman Sherryl - - 2012
With this issue, beginning Volume 121, the editorial team shifts from the strong leadership of David Watson to a team under my direction. Approaching 125 years of publication, the Journal of Abnormal Psychology has earned its place as the preeminent outlet for research in psychopathology. With gratitude to the newly ...
Cao Dingcai D Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1905 W. Taylor Street, Room 149, Chicago, Illinois 60612, USA. - - 2012
This study investigated the mechanisms of flicker detection suppression by measuring mesopic rod and cone critical flicker frequencies (CFFs) at different center and surround illuminance levels. Stimuli were generated with a four-primary photostimulator that provided independent control of rod and cone excitations. The results showed that dim surrounds ≤0.2 Td ...
Smithson Hannah E - - 2012
We present a new commentary on Robert Grosseteste's De colore, a short treatise that dates from the early 13th century, in which Grosseteste constructs a linguistic combinatorial account of color. In contrast to other commentaries (e.g., Kuehni & Schwarz, Color Ordered: A Survey of Color Order Systems from Antiquity to ...
Linkins Lori-Ann - - 2012
Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and stroke. The methods of this guideline follow the Methodology for the Development of Antithrombotic Therapy and Prevention of Thrombosis Guidelines: Antithrombotic ...
Ousey J C - - 2012
Prostaglandins play an essential role during the perinatal period in the mare. Prostaglandin concentrations are low for the majority of pregnancy due to the regulatory action of progestagens on those enzymes responsible for metabolism of prostaglandins. Towards term, prostaglandin concentrations gradually increase, closely associated with upregulation of the fetal hypothalamo-pituitary-adrenal ...
Bernardo Carla de Oliveira Cde - - 2012
To assess the association of parents' nutritional status, and dietary and sociodemographic factors with overweight/obesity in schoolchildren in Florianópolis Island, Santa Catarina State, Brazil, this cross-sectional epidemiological study examined 2,826 schoolchildren 7 to 14 years old, classified according to body mass index curves for age and sex recommended by the ...
Kang Para - - 2012
Consider a feature of a stimulus (such as color, luminance, or spatial frequency) that changes over time along a continuum. When a second stimulus is briefly pulsed with the same feature value as the first stimulus, the two stimuli are not perceived to match. Instead, the continuously changing stimulus is ...
Strenger T - - 2012
Over the last decade, bone conducting hearing aids, cochlear implants and implantable hearing aids have come to represent additional treatment options in clinical routine-alongside conventional hearing aids-for hearing impaired patients. Thanks to experience gained in recent years with implantable hearing aids and the consistent evaluation of functional results, the original ...
Zollner U - - 2012
Malformations of the central nervous system are among the most frequent congenital anomalies. At best, a qualified and standardised screening of the foetal brain is possible between the 18th and the 22nd week. The newly decided modification of the maternity directives envisages an extended screening upon request. This extended screening ...
Mak Joey Y Y - - 2012
To investigate the association of high myopia with common single-nucleotide polymorphisms (SNPs) in the IGF1, IGFBP3, and IGFBP4 genes in a Chinese population. For our case-control study, we recruited 600 unrelated participants: 300 case participants with high myopia (-8.00 diopters or less) and 300 emmetropic controls (within ±1.00 diopter). Twenty-one ...
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