Search Results
Results 301 - 350 of 4120
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Schmitt Christian Martin - - 2012
OBJECTIVE: This investigation focused on a comparison of clinical and histological characteristics after sinus floor augmentation with biphasic calcium phosphate (BCP, Straumann BoneCeramic(®) ), anorganic bovine bone (ABB, Geistlich Bio-Oss(®) ), mineralized cancellous bone allograft (MCBA, Zimmer Puros(®) ), or autologous bone (AB). MATERIALS AND METHODS: Thirty consecutive patients with ...
Shi Dashuang D Center for Genetic Medicine Research and Department of Integrative Systems Biology, Children's National Medical Center, The George Washington University, Washington, District of Columbia 20010, USA. - - 2012
Putrescine carbamoyltransferase (PTCase) catalyzes the conversion of carbamoylputrescine to putrescine and carbamoyl phosphate (CP), a substrate of carbamate kinase (CK). The crystal structure of PTCase has been determined and refined at 3.2 Å resolution. The trimeric molecular structure of PTCase is similar to other carbamoyltransferases, including the catalytic subunit of ...
Choi Kup-Sze - - 2012
Purpose: To motivate children with intellectual disabilities (ID) to learn handwashing and improve their performance by using computer-assisted teaching method. Method: A teaching program was implemented using a computerized teaching station with faucet, soap dispenser and towel dispenser as user interface. In response to the children's actions, animations were shown ...
Holliday Kiel - - 2012
The aim of this work is to assess the effect of ligand strength, symmetry, and coordination number on solid solution formation of trivalent actinides and lanthanides in carbonate and sulfate minerals. This is of particular importance in radionuclide migration where trivalent actinides such as Pu, Am, and Cm are responsible ...
Joseph Joshy - - 2012
Oxidatively generated damage to DNA has been implicated as causing mutations that lead to aging and disease. The one-electron oxidation of normal DNA leads to formation of a nucleobase radical cation that hops through the DNA until it is trapped irreversibly, primarily by reaction at guanine. It has been observed ...
Trama Ashley M - - 2012
The immune systems of wild rats and of laboratory rats can been utilized as models of the human immune system in pre-industrial and post-industrial societies, respectively. In this study, lymphocyte phenotypes in wild rats were broadly characterized, and the results were compared to those obtained by us and by others ...
Bensinger W W University of Washington and the Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA. - - 2012
Allogeneic stem cell transplant for multiple myeloma (MM) is one treatment associated with long-term disease-free survival. The high incidence of treatment-related mortality and relapses, however, are important reasons for controversy about the role of allografting in the management of MM. We reviewed our results of allografting for MM spanning a ...
Mazurek K A KA Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, - - 2012
The biological central pattern generator (CPG) integrates open and closed loop control to produce over-ground walking. The goal of this study was to develop a physiologically based algorithm capable of mimicking the biological system to control multiple joints in the lower extremities for producing over-ground walking. The algorithm used state-based ...
Banzhoff Angelika A Novartis Vaccines and Diagnostics, Marburg, Germany. - - 2012
Seasonal influenza causes clinical illness and hospitalization in all age groups; however, conventional inactivated vaccines have only limited efficacy in young children. MF59(®), an oil-in-water emulsion adjuvant, has been used since the 1990s to enhance the immunogenicity of influenza vaccines in the elderly, a population with waning immune function due ...
Moll Daniel - - 2012
OBJECTIVE: The purpose of this prospective clinical study was to evaluate the outcome of telescopic crown-retained removable dental prostheses (TCR-RDPs) on implants and teeth according to different numbers of abutments. MATERIAL AND METHODS: Between 2000 and 2002, 33 patients received implant or tooth-implant-supported TCR-RDPs. The patients were divided into four ...
Martínez Ana - - 2012
Mangosteen (Garcinia mangostana) is considered the queen of the tropical fruits. It has a dark red pericarp that is rich in bioactive compounds including xanthones, which have been classified as very good antioxidants from several experimental results. In this work, the antioxidant properties of twenty xanthones isolated from the pericarp ...
Baer Tomas - - 2012
Threshold photoelectron photoion coincidence (TPEPICO) has been used to study the sequential photodissociation reaction of internal energy selected 1,2-diiodoethane cations: C2H4I2+  C2H4I+ + I  C2H3+ + I + HI. In the first I-loss reaction, the excess energy is partitioned between the internal energy of the fragment ion C2H4I+ ...
Yip Julie K - - 2012
To investigate the association between the use of oral bisphosphonate therapy and dental implant failure. The case-control study involved 337 female patients, aged 40 years and older, who had 1181 implants placed at the Department of Periodontology and Implant Dentistry at New York University College of Dentistry between January 1997 and ...
Kohrt Holbrook E - - 2012
Trastuzumab, a monoclonal antibody targeting human epidermal growth factor receptor 2 (HER2; also known as HER-2/neu), is indicated for the treatment of women with either early stage or metastatic HER2(+) breast cancer. It kills tumor cells by several mechanisms, including antibody-dependent cellular cytotoxicity (ADCC). Strategies that enhance the activity of ...
Yanyu Xiao - - 2012
The purpose of this study was to investigate the influence of the structure and the composition of water/Aerosol-OT (AOT)-Tween 85/isopropylmyristate (IPM) microemulsion system (WATI) on transdermal delivery of 5-fluorouracil (5-FU). The structure of WATI was characterized by measuring surface tension, density, viscosity, electric conductivity, and differential scanning calorimetry. The effect ...
Li Yajun - - 2012
A new Rh-catalyzed intramolecular coupling reaction of a CF(2)Br group with a 2-aryl of indole or pyrrole via C-H bond activation is presented. This reaction represents a new way of incorporating difluoromethylene groups into organic compounds. Preliminary mechanistic studies suggest that this reaction might not occur via a conventional free ...
Van Herck Koen K Vaccine & Infectious Disease Institute (WHO Collaborating Centre), Centre for the Evaluation of Vaccination, Antwerpen, - - 2012
Antibody persistence and immune memory against hepatitis A (HAV) in adults in a low endemicity country, 15 y after immunisation with two doses of HAV vaccine has been demonstrated. This communication provides additional information on antibody persistence up to Year 17 from two of the longest follow-up studies [NCT00289757/NCT00291876]. In ...
Martin Richard L - - 2012
Molecular interaction fields provide a useful description of ligand-binding propensity and have found widespread use in computer-aided drug design, for example, to characterise protein binding sites and in small molecular applications such as three-dimensional quantitative-structure activity relationships, physicochemical property prediction and virtual screening. However, the grids on which the field ...
Wang Juan - - 2012
Cell detachment is an ordinary cell behavior, and acts a significant role in numerous physiological processes. In addition, as massive cell groups have specific shapes in vivo, selectively controlling detachment of patterned cells is crucial for both clinical and fundamental research, because it may act as a platform for studying ...
Sisó C - - 2012
The purpose of this study was to describe the variation in listeriosis infection incidence during pregnancy over a 25-year period based on salient clinical and laboratory features compiled in a tertiary referral hospital and to depict the clinical characteristics of these cases. A cohort was created of all cases of ...
Zhang Haibin - - 2012
Aims: The purpose of this study was to characterize left ventricular (LV) intracavitary flow during the isovolumic contraction (IVC) period in humans using vector flow mapping. Methods: Color flow Doppler imaging was performed from the apical long-axis view in 61 patients with heart failure and 58 healthy volunteers. Doppler flow ...
Waheed Mohammad Tahir MT Department of Applied Plant Sciences and Applied Plant Biotechnology, University of Natural Resources and Applied Life Sciences (BOKU), Vienna, - - 2012
Several types of human papillomavirus (HPV) are causatively associated with cervical cancer, which is the second most common cancer in women worldwide. HPV-16 and 18 are among the high risk types and responsible for HPV infection in more than 70% of the cases. The majority of cervical cancer cases occur ...
Doorley Gerard W - - 2012
Two-colour fluorescence microscopy was used to track the cellular internalization of nanoparticles exposed to extracellular serum proteins. Single particle tracking revealed that nanoparticles and serum proteins are internalized and transported through the cell as a single complex. This study demonstrates the importance of nanoparticle-protein interactions in cellular applications.
Sahana Animesh - - 2012
An indole based naphthalene derivative is reported as a highly selective fluorescent probe for azide ion in aqueous ethanol. The probe is applied for cell imaging of the N(3)(-) ion in contaminated living cells. Both experimental and theoretical studies have been performed to figure out the plausible mechanism of fluorescence ...
Wang Hsi-Kai - - 2012
The aryl hydrocarbon receptor (AhR), a transcription factor mediating xenobiotic detoxification, plays a considerable role in regulatory T cell (Treg) induction. Tregs regulate the immune system, thus suppressing allergies and autoimmune diseases. This study aims to identify new types of anti-allergic dietary factors, with focus on the flavonoids with potential ...
Mellon Jay - - 2012
Abstract Racemic gossypol and derivatives gossypolone and apogossypolone demonstrated significant growth inhibition against a diverse collection of filamentous fungi that included Aspergillus flavus, A. parasiticus, A. alliaceus, A. fumigatus, Fusarium graminearum, F. moniliforme, Penicillium chrysogenum, P. corylophilum and Stachybotrys atra. The compounds were tested in a Czapek agar medium at ...
Vasiljevic Jelena - - 2012
The paper considers the method, based on multifractal (MF) analysis, for classifying the shape of tissue cells from microscopis images, identifying the primary cancer in cases of metastasis bone disease. Diagnosis of primary cancer is of great importance, because further treatment depends on how successful and accurate that diagnosis is. ...
Borges Alan Maia AM College of Medicine, Institute of Life Science, Swansea University, - - 2012
Bacterial infections commonly cause bovine endometritis and infertility via innate immune pathways. However, mechanistic studies using isolated cells or chopped tissue may be compromised by the disruption of endometrial architecture and release of damage-associated molecular patterns. So, this study aimed to establish an ex vivo model of intact bovine endometrium ...
Huzair Farah F Innogen, The Open University, Milton Keynes, UK. - - 2012
As Product Development Partnerships (PDPs) emerge and evolve in response to the need for vaccines, this paper re-examines the oldest and most successful PDP in the vaccine field; that which year after year, produces and reinvents influenza vaccines. This paper describes the influenza vaccine production and innovation system and reviews ...
Madine Jillian - - 2012
The peptide AAKLVFF assembles into fibrils in water and nanotubes in methanol. Solid-state NMR data are consistent with fibrils constructed from β-sheet bilayers and nanotubes bounded by a wall of offset β-sheet monolayers. Remarkably distinct morphologies are thus traced to subtle differences in the arrangement of the same fundamental building ...
Wei Peng - - 2012
2-(2-Methoxyphenyl)-1,3-Dimethyl-1H-Benzoimidazol-3-ium iodide (o-MeO-DMBI-I) was synthesized and employed as a strong n-type dopant for fullerene C60, a well-known n-channel semiconductor. The co-evaporated thin films show a maximum conductivity of 5.5 S/cm at a 8.0wt% (14mol%) doping concentration, which is the highest value reported so far for molecular n-type conductors. o-MeO-DMBI-I can ...
Wang Wei - - 2012
PAF-16 which is based on tetrahedral units (TCPSi) and triangular building units, shows both high thermal stability and high chemical stability. The surface area of PAF-16 can be tuned by changing the reaction temperature and ratio of monomer and catalyst. PAF-16 also shows considerable adsorption capacity of CO(2).
Rekecki A - - 2012
The location and cell damage caused by Vibrio anguillarum, the causative agent of classical vibriosis, within the developing gut of the newly hatched sea bass, Dicentrarchus labrax (L.), is unknown. A gnotobiotic sea bass model was used to investigate the early interactions of V. anguillarum with sea bass larvae. In the ...
Najafpour Mohammad Mahdi - - 2012
We describe here the ability of manganese oxide monosheets to aggregate to form layered structures with 4-aminophenol molecules. These aggregated monosheets could be considered as the first step to synthesize a self-assembled layered hybrid of phenol-manganese ions with phenol and manganese(iii) and (iv) as exists in the water oxidizing complex ...
Schmidt Reinhard - - 2012
The endoperoxide of mesodiphenylhelianthrene MDHPO has been studied in detail with respect to fluorescence and photo-induced rearrangement. MDHPO proved to be non-fluorescent, although its absorption spectrum is dominated at the low energy side by a strong ππ* band with a maximum at 429.5 nm. Irradiation of that band effects rearrangement ...
Bernassau A L - - 2012
We describe the construction of a ultrasonic device suitable for micro patterning particles and cells for tissue engineering applications. The device is formed by seven transducers shaped into a heptagon cavity. By exciting two and three transducers simultaneously, lines or hexagonal shapes can be formed with beads and cells. Furthermore, ...
Kanafani Zeina A - - 2012
Tedizolid phosphate (TR-701) is a new oxazolidinone prodrug that is transformed in the serum into the active drug tedizolid (TR-700). Tedizolid acts by inhibiting protein synthesis and has broad activity against Gram-positive pathogens, including strains that are resistant to linezolid. This review summarizes the currently available data on this new ...
Balansky Roumen - - 2012
Cigarette smoke (CS) and dietary factors play a major role in cancer epidemiology. At the same time, however, the diet is the richest source of anticancer agents. Berries possess a broad array of health protective properties and were found to attenuate the yield of tumors induced by individual carcinogens in ...
Delangle Pascale - - 2012
Wilson's disease is an orphan disease due to copper homeostasis dysfunction. Mutations of the ATP7B gene induces an impaired functioning of a Cu-ATPase, impaired Cu detoxification in the liver and copper overload in the body. Indeed, even though copper is an essential element, which is used as cofactor by many ...
Ohguri Takayuki - - 2012
The purpose of this study was to evaluate the efficacy and toxicity of the postoperative radiotherapy in patients with incompletely resected NSCLC, and to investigate whether the histological subtype is a prognostic factor. Forty-one incompletely resected NSCLC patients who underwent postoperative radiotherapy were retrospectively analyzed. The microscopic residual tumor (R1 ...
Hasnain Syed M - - 2012
Airborne fungal spores are well known to cause respiratory allergic diseases particularly bronchial asthma, allergic rhinitis, rhino-conjunctivitis and allergic broncho-pulmonary aspergillosis in both adults and children. In order to monitor and analyze airborne fungal flora of the Karachi environment, an aeromycological study was conducted using a Burkard 7-Day Recording Volumetric ...
Li Yan - - 2012
Ab initio simulation of the transition from the crystalline to the amorphous phase of a phase-change material doped with Fe impurities. We study the structural and magnetic properties of both phases and provide a link between the magnetic contrast recently observed in these materials and the drastic change in local ...
Brehm Michael A MA Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. - - 2012
Basic research in transplantation immunology has relied primarily on rodent models. Experimentation with rodents has laid the foundation for our basic understanding of the biological events that precipitate rejection of non-self or allogeneic tissue transplants and supported the development of novel strategies to specifically suppress allogeneic immune responses. However, translation ...
Sanz J - - 2012
Attempts to optimize outcomes in cord blood transplantation (CBT) by using new conditioning regimens and standardization of cord blood unit selection are warranted. In all, 88 patients (18 children and 70 adults) with hematological malignancy from nine Spanish institutions underwent a single-unit CBT after an i.v. BU-based myeloablative conditioning regimen. ...
Naor Omer O Faculty of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, - - 2012
Ultrasound waves, widely used as a non-invasive diagnostic modality, were recently shown to stimulate neuronal activity. Functionally meaningful stimulation, as is required in order to form a unified percept, requires the dynamic generation of simultaneous stimulation patterns. In this paper, we examine the general feasibility and properties of an acoustic ...
Tubek Sławomir S Internal Medicine Ward of the Voivedship Hospital, Opole, - - 2012
This case report describes a 52-y-old male patient who, one week after influenza vaccination, presented with abdominal symptoms: pain in the right epigastrium followed by liver dysfunction and pyrexia, as well renal failure, muscles pain and consciousness disorders. Immune-complex-like disease and Enterobacter cloacae sepsis due to cholelithic cholecystitis were diagnosed. ...
Karaarslan Sevim - - 2012
IntroductionThe aim of this study was to investigate the importance of myocardial performance index as an additive criterion to Sarnat criteria in differential diagnosis of newborn babies with moderate and severe hypoxic-ischaemic encephalopathy. METHODS: Our study group included 50 healthy term newborn babies and 20 newborn babies with hypoxic-ischaemic encephalopathy. ...
Meinhardt-Wollweber Merve - - 2012
Low levels of vitamin D have been implicated in a wide variety of health issues from calcemic diseases to cancer, diabetes and cardiovascular disease. For most humans, the majority of vitamin D(3) is derived from sunlight. How much vitamin D is produced under given exposure conditions is still widely discussed. ...
Brodaty Henry - - 2012
ABSTRACTBackground: Life expectancy with dementia directly influences rates of prevalence and service needs and is a common question posed by families and patients. As well as years of survival, it is useful to consider years of life lost after a diagnosis of dementia.Methods: We systematically reviewed the literature on mortality ...
Huang Huan - - 2012
A series of isomerically pure alkynyl substituted fullerenol derivatives such as C60(OH)6(O(CH2)3CCH)2 were synthesized through Lewis acid catalyzed epoxy ring-opening and/or SN1 replacement reactions starting from fullerene-mixed peroxide C60(O)(t-BuOO)4. Copper-catalyzed azide-alkyne cycloaddition readily converted the terminal alkynyl groups into triazole groups. Intramolecular oxidative alkyne coupling afforded a fullerenyl crown ether ...
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