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Vázquez-Medina José Pablo JP School of Natural Sciences, University of California Merced, 5200 N Lake Road, Merced, CA 95343, USA. - - 2012
While diving, seals are exposed to apnea-induced hypoxemia and repetitive cycles of ischemia/reperfusion. While on land, seals experience sleep apnea, as well as prolonged periods of food and water deprivation. Prolonged fasting, sleep apnea, hypoxemia and ischemia/reperfusion increase oxidant production and oxidative stress in terrestrial mammals. In seals, however, neither ...
Han Buket - - 2012
Aims: To study the efficacy of azithromycin in combination with nonsurgical periodontal therapy on clinical, microbiological parameters and gingival crevicular fluid (GCF) matrix metalloproteinases-8 (MMP-8) levels over 6 months in severe generalized chronic periodontitis patients. Methods: Twenty eight out of 36 severe generalized chronic periodontitis patients were included in this ...
Meyer Eli - - 2012
Panicum hallii is an emerging model for genetic studies of agronomic traits in Panicum, presenting a tractable diploid alternative study system to the tetra- or octaploid biofuel crop switchgrass (P. virgatum). To characterize the gene complement in P. hallii var. filipes and enable gene expression analysis in this system we ...
Rai Mahendra K - - 2012
In the present scenario, pharmaceutical and biomedical sectors are facing the challenges of continuously increase in the multi-drug resistant human pathogenic microbes. Re-emergence of multi-drug resistant microbes is facilated due to drug and/or antibiotic resistance, which is the acquired way of microbes for their survival and multiplication in uncomfortable environment. ...
Garcia Xiomara - - 2012
Background: The clinical characteristics of patients with Aspergillus isolation while supported on extracorporeal membrane oxygenator (ECMO) remain unclear. Objectives: We present a case report of angioinvasive Aspergillus infection on an infant supported on ECMO and also investigate outcomes among patients with Aspergillus infection reported to the Extracorporeal Life Support Organization ...
Syed Sarfaraz U A H - - 2012
This study uses a computer model to simulate a quadrupole mass filter (QMF) instrument under different operating conditions for Mathieu stability zones 1 and 3. The investigation considers the factors that limit the maximum resolution (R(max)), which can be obtained for a given QMF for a particular value of scan ...
Gao Tian - - 2012
In order to identify epigenetic markers of β-thalassemia, a genome-wide profiling method named differential methylation hybridization was used to search these differentially methylated genes. Unsupervised hierarchical clustering and molecular annotation system were used to analyze the data, and methylation-specific PCR and real-time PCR were used to confirm the differentially methylated ...
Moradi Morteza - - 2012
Using first principle calculations, we investigated cation-π interactions between alkali cations (Li(+), Na(+), and K(+)) and pristine C(24) or doped fullerenes of BC(23), and NC(23). The most suitable adsorption site is found to be atop the center of a six-membered ring of the exterior surface of C(24) molecule. Interaction energies ...
Sellars M J - - 2012
In this study, we trialed 6-dimethylaminopurine (6-DMAP) chemical shocks to induce meiosis I or meiosis II Pacific White shrimp, Litopenaeus vannamei, triploids for the first time, and cold temperature shocks to induce meiosis II L. vannamei triploids as done previously. Inductions were performed on 37 spawnings in total with experiments ...
Scafaro Andrew P - - 2012
Oryza meridionalis is a wild species of rice, endemic to tropical Australia. It shares a significant genome homology with the common domesticated rice Oryza sativa. Exploiting the fact that the two species are highly related but O. meridionalis has superior heat tolerance, experiments were undertaken to identify the impact of ...
Lee Jin Hee - - 2012
BACKGROUND: Clinicopathologic features and long-term outcomes in patients with scirrhous hepatocellular carcinoma (S-HCC) are not fully defined. METHODS: We compared data of 37 patients with S-HCC and 604 with usual HCC (U-HCC) undergoing surgery. RESULTS: The S-HCC group showed less HBV infection (78.4 vs. 92.0%, P = 0.02), low serum AFP level ...
Brands Myrte - - 2012
OBJECTIVE: Insulin resistance and hyperinsulinemia precede the onset of obesity-induced DM2. The early adaptation of the β-cell during the initial phase of overfeeding and weight gain has only been partly elucidated. We studied the early changes in insulin clearance and β-cell responsivity during a positive and negative energy balance in ...
Hadrich Inès - - 2012
Although the arsenal of agents with anti-Aspergillus activity has expanded over the last decade, mortality due to invasive aspergillosis remains unacceptably high. Resistance of the Aspergillus spp. species to antifungal drugs increased in the last 20 years with the increase in antifungal drugs use and might partially account for treatment failures. ...
Pellerin Olivier - - 2012
PURPOSE: To evaluate the efficacy and safety of superselective embolization of the uterine arteries in a postpartum hemorrhage. MATERIALS AND METHODS: Between November 2004 and January 2011, a total of 44 consecutive women (median ± standard deviation age 34 ± 3 years, range 23-41 years) were referred to our institution for postpartum intractable hemorrhage management. All ...
Xiong Hua - - 2012
Abnormalities in signal transducer and activator of transcription (STAT) signaling, especially STAT3 and STAT5, are involved in the oncogenesis of several human cancers, including gastric cancer (GC). However, the downstream targets of STAT3 and STAT5 are not fully identified, and the precise roles and the prognostic value of STAT3 and ...
Kuh D D MRC Unit for Lifelong Health and Ageing, London, UK. - - 2012
Healthy ageing across the life course (HALCyon) is an interdisciplinary research collaboration that harnesses the power of nine UK cohort studies to discover life course influences on physical and cognitive capability, social and psychological well-being, and underlying biology. In this symposium, HALCyon co-investigators reported the first wave of findings from ...
Poulou Myrto - - 2012
BACKGROUND: The Cystic Fibrosis database includes amongst the 1893 gene mutations and polymorphisms a lot of missense mutations, the disease status of which still remains unproven. In populations with high rates of CFTR mutation heterogeneity, molecular diagnosis is difficult often causing counseling difficulties especially in cases of rare and/or novel ...
Lee Jihyun - - 2012
This article reviews cognitive interviewing (CI) as a survey pretesting method in cross-national settings. Particularly, semi-structured cognitive interviewing (SSCI) using direct probing is advocated when CI involves multiple countries/languages. Four major groups of fundamental issues are discussed: conceptual, measurement, procedural, and practical. The conceptual issues relate to the nature of ...
Paoli A - - 2012
The influence of nutrition on skin health is a growing research area but the findings of various studies on the effect of diet on the development of acne have often been contradictory. The general opinion among researchers has oscillated between two different, opposing positions: that diet either is or is ...
Xue Pan - - 2012
Enzyme-linked immunosorbent assay (ELISA), horseradish peroxidase (HRP)-catalyzed fluorescent reaction, and oxalate chemiluminescence analysis have been combined to develop a highly sensitive, simple, and rapid method for analysis of bovine serum albumin (BSA) based on a pair of specific monoclonal antibodies in vaccines. A typical "sandwich type" immunoassay was used. Reaction ...
Terada Kei-Ichi - - 2012
We studied electron transport of Ru-complex multilayer films, whose structure resembles redox-active complex film that is reported in literature to have long-range electron transport abilities. Hydrogen bond formation in terms of pH control was used to induce spontaneous growth of Ru complex multilayer. We made a cross-check between electrochemical measurements ...
Heuer Herbert H IfADo, Leibniz Research Centre for Working Environment and Human Factors, Ardeystraße 67, 44139 Dortmund, Germany. - - 2012
Studies with perturbed and augmented haptic information during adaptation to novel visuo-motor transformations suggest that haptic information might be neglected. However, the notion of functional haptic neglect during adaptation is counterintuitive for different reasons. Therefore, we sought conditions where haptic guidance during adaptation results in benefits. First, we mixed guided ...
Lombel Rebecca M - - 2012
PURPOSE: In critically ill pediatric patients, fluid overload (FO) >10% has been identified as a threshold for possible interventions, including initiation of continuous renal replacement therapy (CRRT). However, multiple definitions have been reported, and there remains no consensus method for FO calculation. The goal of this study was to compare ...
Munné Santiago - - 2012
OBJECTIVE: To determine the extent of intra-age and intercycle variations in the frequency of first polar body aneuploidy in two consecutive cycles of oocyte retrieval undertaken by the same patient within 1 year. DESIGN: Retrospective study. SETTING: Fertility centers. PATIENT(S): Infertile couples undergoing IVF. INTERVENTION(S): Patients underwent two consecutive cycles ...
Ghanavi Parisa - - 2012
The efficacy of existing articular cartilage defect repair strategies are limited. Native cartilage tissue forms via a series of exquisitely orchestrated morphogenic events spanning through gestation into early childhood. However, defect repair must be achieved in a non-ideal microenvironment over an accelerated time-frame compatible with the normal life of an ...
Antel Jack - - 2012
Multiple sclerosis (MS), the most frequent demyelinating disease, is characterized by a variable disease course. The majority of patients starts with relapsing remitting (RR) disease; approximately 50-60% of these patients progress to secondary progressive (SP) disease. Only about 15% of the patients develop a progressive disease course from onset, termed ...
Celik Derya - - 2012
Our purpose was to study the relationship between latent trigger points (LTrP) and levels of depression in healthy subjects. A total of 76 healthy subjects consisting of 40 men and 36 women (mean age, 25.4 ± 4.8 years; age range, 19-42 years) from the School of Physical Therapy and Rehabilitation and the Orthopaedics and ...
Subramanian Venkataraman - - 2012
INTRODUCTION: Interpretation of video capsule data is time-consuming. Olympus capsule endoscopy (CE) software systems are equipped with auto-speed-adjusted and express-selected playback modes and overview function in an effort to reduce reading times. The clinical efficacy of these new playback features is unknown. Our objective was to evaluate the diagnostic yield ...
Pundik Svetlana - - 2012
Purpose: Intensive gait training can produce improvements in gait and function (>6 months after stroke); however, findings are mixed for enhanced life-role participation. Therefore, it is unclear if improved gait and function translate into life-role participation gain. Our objective was to evaluate whether intensive gait therapy can produce improvements in ...
Kario Kazuomi - - 2012
The devastating Great East Japan Earthquake, which was 9.0 on the Richter scale, occurred on March 11, 2011. Japan experienced the Great Hanshin-Awaji Earthquake 16 years ago, and I was working at the epicenter, and reported the characteristics of the earthquake-associated cardiovascular risk and high blood pressure (BP) found during ...
Negi Sangeeta - - 2012
In the present work, evaluation of different conventional techniques, i.e., chemical oxygen demand (COD), biological oxygen demand, elemental analysis, Fourier transform infrared (FTIR), and gas chromatography used for estimating biodegradation of grease waste was carried out. In this order grease waste was incubated with Penicillium chrysogenum for 7-30 days and analyzed ...
Garcia-Mazcorro Jose F - - 2012
The effect of a proton-pump inhibitor on gastrointestinal microbiota was evaluated. Eight healthy 9-month-old dogs (4 males and 4 females) received omeprazole (1.1 mg/kg) orally twice a day for 15 days. Fecal samples and endoscopic biopsies from the stomach and duodenum were obtained on days 30 and 15 before omeprazole ...
Tordoff June - - 2012
Background There is limited information in New Zealand about community pharmacists' perceptions of services that benefit older people. Objectives To explore the perceptions of community pharmacists' of services that benefit older people; the benefits perceived; and the experiences of pharmacists providing such services. Setting Community pharmacies in New Zealand. Methods ...
Morice Philippe - - 2012
Cervical and ovarian cancers are the most common gynaecological cancers diagnosed during pregnancy. In early-stage cervical cancer during the first and at the beginning of the second trimester, the two main considerations for management of the patient are the tumour size (and stage) and nodal staging. MRI and laparoscopic lymphadenectomy ...
Hickey Edward J - - 2012
OBJECTIVE: To characterize the risk of reintervention after biventricular strategies to treat neonatal critical aortic stenosis, and the effect of reintervention on survival. METHODS: In a multi-institutional inception cohort of 139 neonates, the time-related risk of reintervention was analyzed using parametric multiphase competing-risk models and a modulated renewal repeated-events method. ...
Heise Ruth - - 2012
Chronic skin exposure to ultraviolet light stimulates production of cytokines known to be involved in the initiation of skin cancer. Recent studies in mouse models suggested a role for macrophage migration inhibitory factor (MIF) in the UVB-induced pathogenesis of non-melanoma skin cancer (NMSC). Our studies aimed at defining the pathophysiological ...
Hotta Yudai - - 2012
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) using ribosomal subunit proteins coded in the S10-spc-alpha operon as biomarkers was applied for the classification of the Sphingomonadaceae from the environment. To construct a ribosomal protein database, S10-spc-alpha operon of type strains of the Sphingomonadaceae and their related alkylphenol polyethoxylate ...
Lu Wenjing - - 2012
Repeated batch cultivation was applied to enrich hydrogen fermentative microflora under extreme-thermophilic (70°C) environment. Initial inoculums received from a hydrogen producing reactor fed with organic fraction of household solid wastes. In total seven transfers was conducted and maximum hydrogen yield reached 296 ml H(2)/g (2.38 mol/mol) glucose and 252 ml H(2)/g (2.03 mol/mol) for ...
Chen-Shtoyerman R - - 2012
We describe 7 cases of abnormal karyotypes involving chromosomes Y and 15 in Ethiopian Beta Israel patients: 46,XX, der(15)t(Y;15)(q12;p12) and 46,XY,der(15)t(Y;15)(q12;p12). Six cases were incidentally found in amniocentesis performed for various indications; the indication for karyotyping in 1 case was recurrent abortions. To the best of our knowledge, this is ...
Town Raewyn M - - 2012
The chemodynamics of Cu(II) complexation by humic acid is interpreted in terms of recently developed theory for permeable charged nanoparticles. Two opposing electric effects are operational with respect to the overall rate of association, namely (i) the conductive enhancement of the diffusion of Cu<sup>2+</sup>, expressed by a coefficient <i>f</i><sub>el</sub>, which ...
Ivanova Jasmina I - - 2012
BACKGROUND: Health care costs increase in patients with more severe asthma, but the effect of asthma exacerbations on costs among patients with more severe asthma has not been quantified. OBJECTIVE: This study compared direct health care costs between patients with moderate/severe persistent asthma with and without exacerbations. METHODS: Patients who ...
Gao Jian - - 2012
PURPOSE: Dendritic cell (DC)-based cancer vaccines have become an attractive antitumour therapeutic approach. However, clinical application of current DC-based cancer vaccines has been limited by their ineffectiveness. Heat shock protein 70 from Mycobacterium tuberculosis (TBhsp70) is known to have a potent adjuvant capability to induce maturation of DCs and thus ...
Anagnostopoulos Fotios - - 2012
Physician burnout, as a prolonged response to chronic emotional and interpersonal stressors on the job, has been associated with suboptimal patient care and deterioration in the patient-provider relationship. Although prior studies have identified a range of factors associated with decreased patient satisfaction, most have been conducted in tertiary care settings, ...
Lam Francis - - 2012
The primary objective of this study was to evaluate the hemodynamic effects of dexmedetomidine (DEX) infusion on critically ill neonates and infants with congenital heart disease (CHD). The secondary objective of the study was to evaluate the safety and efficacy profile of the drug in this patient population. A retrospective ...
Harris R C - - 2012
The main determinant of muscle carnosine (M-Carn) content is undoubtedly species, with, for example, aerobically trained female vegetarian athletes [with circa 13 mmol/kg dry muscle (dm)] having just 1/10th of that found in trained thoroughbred horses. Muscle fibre type is another key determinant, as type II fibres have a higher ...
Ghosh Dipak K - - 2012
Nitric Oxide synthases (NOS) produce NO as a molecular signal in the nervous and cardiovascular systems and as a cytotoxin in the immune response. NO production in the constitutive isoforms is controlled by calmodulin regulation of electron transfer. In the tethered shuttle model for NOS reductase function, the FMN domain ...
Saxena Anil K - - 2012
The present study describes a successful application of computational approaches to identify novel Leishmania donovani (Ld) AdoHcyase inhibitors utilizing the differences for Ld AdoHcyase NAD+ binding between human and Ld parasite. The development and validation of the three-dimensional (3D) structures of Ld AdoHcyase using the L. major AdoHcyase as template ...
Marcotte Leah - - 2012
Tubers are cerebral cortical developmental malformations associated with epilepsy and autism in tuberous sclerosis complex (TSC). The disparity between tuber number and severity of neurological impairment often observed in TSC led us to hypothesize that microscopic structural abnormalities distinct from tubers may occur in TSC. Serial frontal to occipital lobe ...
Du Bo-Yu - - 2012
Background: Neuroblastoma (NB) is the most common extracranial solid tumor in infants. Currently, the mainstay of NB chemotherapy is combination treatment with some traditional drugs, but these combination regimens are always inefficient. Methods: The aim of this study was to evaluate the inhibitory effect of a combination of doxorubicin and ...
Singh Dheeraj Kumar - - 2012
Raman spectra of neat pyrrole (C(4)H(5)N) and its binary mixtures with dichloromethane (CH(2)Cl(2), DCM) with varying mole fractions of C(4)H(5)N from 0.1 to 0.9 were recorded in order to monitor the influence of molecular interaction on spectral features of selected vibrational bands of pyrrole in the region 600-1600 cm(-1). Only ...
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