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Results 451 - 500 of 4120
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Kang Jin Young - - 2012
Tracheostomy tubes are thought to increase the incidence of aspiration and several mechanisms that might cause this have been suggested. Some studies reported alterations in laryngeal elevation during swallowing, which they attributed to an anchoring effect of the tracheostomy tube resulting in dysphagia. The purpose of the present study was ...
Mousa Shaker A - - 2012
Effects of unfractionated heparin and low-molecular-weight heparins (LMWHs) on human microvascular endothelial cell sprouting (tube formation assay) in vitro were determined. Antiangiogenesis efficacy of commercially available LMWHs tinzaparin and enoxaparin in the chick chorioallantoic membrane (CAM) model of growth factor-induced angiogenesis was compared. The LMWH tinzaparin was fractionated into different ...
Wang Jie - - 2012
Cordymin is a peptide purified from the medicinal mushroom Cordyceps sinensis. The present study investigated the effects of Cordymin in prevention of focal cerebral ischemic/reperfusion (IR) injury. The right middle cerebral artery occlusion model was used in the study. The effects of Cordymin on mortality rate, neurobehavior, grip strength, glutathione ...
Formosa Robert - - 2012
Deregulation of the Wnt pathway has been implicated in oncogenesis of numerous tissues including the pituitary gland. Immunohistochemical localization and quantification of β-catenin, Cyclin D1, c-MYC and Survivin expression in 47 pituitary adenomas (35 non-functioning, seven GH-secreting, three prolactinomas, two ACTH-secreting tumour) and six normal controls was undertaken in this ...
Wagner Svenja - - 2012
The human cytomegalovirus (HCMV) UL78 ORF is considered to encode an orphan 7-transmembrane receptor. However, until now, the UL78 protein (pUL78) has not been characterized. Here, we have investigated the expression of pUL78 and found it mainly associated with the endoplasmic reticulum. However, we provide evidence that pUL78 is also ...
Roberts Rachel M - - 2012
Abstract Objective: Adults with craniofacial conditions experience more psychosocial problems than the general population but little is known about the factors that render a person more or less susceptible to these problems. Guided by research on adults with other conditions that affect appearance, this study examined predictors of psychosocial outcomes ...
Girón-Calva P Saraí - - 2012
Volatiles emitted from stressed plants can induce resistance in healthy neighbors. It remains unknown, however, how plants perceive volatiles and convert them into internal signals. We exposed lima bean (Phaseolus lunatus L.) to different concentrations of either of two volatiles, nonanal and methyl salicylate (MeSA), over 6 or 24 h. Plant ...
Hixson Josh Lee - - 2012
A method for determining ethyl coumarate and ethyl ferulate in wine using GC-MS with deuterium-labelled analogues has been developed and used to measure the evolution of these two esters during production of two commercial monovarietal red wines, cv. Grenache and Shiraz. During fermentation, the concentration of ethyl coumarate rose from ...
Tomioka Kenji - - 2012
Many physiological functions of insects show a rhythmic change to adapt to daily environmental cycles. These rhythms are controlled by a multi-clock system. A principal clock located in the brain usually organizes the overall behavioral rhythms, so that it is called the "central clock". However, the rhythms observed in a ...
Wagner Nicole D - - 2012
The use of biochemical and molecular indices of nutritional stress have recently been promoted for their potential ability to assess the in situ nutritional state of zooplankton. The development and application of these indicators should at least consider the cross-reactivity with other nutritional stressors. We examined the potential usefulness of ...
Yardim Hasan H Van Training and Research Hospital, Van, - - 2012
We aimed to evaluate the frequency of catheter-related internal jugular vein (IJV) thrombosis, associated factors, and the anatomical variations of IJV in hemodialysis patients. Hemodialysis patients were evaluated with B-mode ultrasonography (USG). Participants in the prospective group were evaluated using USG prior to catheter insertion, 10 days after catheter insertion, ...
Zhou Guang-Jie - - 2012
PURPOSE: The objective of this study was to determine the removal of zinc and copper by two freshwater green microalgae Chlorella pyrenoidosa and Scenedesmus obliquus and to investigate changes of algal ultrastructure and photosynthetic pigment. METHODS: Algal cells were exposed for 8 days to different initial zinc or copper concentrations. Heavy ...
Wesnes Stian Langeland - - 2012
To investigate to what extent a physician's place of graduation is associated with the physician choosing a career as a general practitioner (GP), and identify factors in the curriculum that could predict a general practice career. Cross-sectional study based on the membership database of the Norwegian Medical Association. Physicians working ...
Klemm Otto - - 2012
The collection of fog water is a simple and sustainable technology to obtain fresh water for afforestation, gardening, and as a drinking water source for human and animal consumption. In regions where fresh water is sparse and fog frequently occurs, it is feasible to set up a passive mesh system ...
Cassidy Lindsey - - 2012
Details of piriformis syndrome, including the proper diagnosis and most effective form of treatment, continue to be controversial. While the cause, diagnosis, and treatment of piriformis syndrome remain elusive, many studies have been conducted to investigate newly developed diagnostic techniques as well as various treatment options for piriformis-induced sciatica. Despite ...
Ahmet Ismayil - - 2012
PURPOSE: A salutary effect of β(2) adrenergic receptor (AR) agonist, fenoterol has been demonstrated in a rat model of post-myocardial infarction (MI) dilated cardiomyopathy (DCM). Recent reports on single cardiomyocyte experiments suggested that out of two enantiomers, RR and SS, that constitute a racemic mixture of fenoterol, only RR-enantiomer is ...
Kromen Wolfgang - - 2012
For a definitive diagnosis of myocarditis, different strategies like analysis of late gadolinium enhancement (LGE) in cardiovascular magnetic resonance imaging (CMR) up to invasive endomyocardial biopsy have been applied. The objective of the study was to investigate inflammatory changes like left ventricular wall thickening and increase of ventricular mass and ...
Kawahara Yosuke - - 2012
High-grade (World Health Organization grades II and III) meningiomas grow aggressively and recur frequently, resulting in a poor prognosis. Assessment of tumor malignancy before treatment initiation is important. We attempted to determine predictive factors for high-grade meningioma on magnetic resonance (MR) imaging before surgery. We reviewed 65 meningiomas (39 cases, ...
Zhang Liang L Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois, - - 2012
Human thymine DNA glycosylase (hTDG) efficiently excises 5-carboxylcytosine (5caC), a key oxidation product of 5-methylcytosine in genomic DNA, in a recently discovered cytosine demethylation pathway. We present here the crystal structures of the hTDG catalytic domain in complex with duplex DNA containing either 5caC or a fluorinated analog. These structures, ...
Du Hai - - 2012
Geosmin is the major cause of the common earthy off-flavor in light-aroma type Chinese liquor and, thus, highly detrimental to the aromatic quality. To find out its origin, the evolving process of geosmin in light-aroma type liquor making was monitored, and microbial analysis of Daqu containing geosmin was carried out. ...
Ali Norliza - - 2012
The diagnosis of nonbacterial thrombotic endocarditis (NTBE) is rarely made during life. This report describes a child who had high-grade non-Hodgkin's lymphoma with NTBE and multiple systemic embolism. The transthoracic echocardiographic findings of mitral valve leaflet vegetations and progressive regurgitation led to surgical resection of the vegetations. A high index ...
Kumar Ravinder - - 2012
Animals (n = 152) suffering with mastitis were used to study association between immunoglobulin G3 (IgG3) genotypes and staphylococcal mastitis. Thus, animals (affected and unaffected) were evaluated using PCR-RFLP. Restriction digestion of amplicons of IgG3 using BstYI showed allele A and, genotypes AC, AB and AA predominated in Karan Fries, Sahiwal and ...
Cil Habib - - 2012
Aim: To investigate the relationship between mean platelet volume (MPV) and in-hospital deep venous thrombosis (DVT). Material and methods: 147 patients with the diagnosis of DVT and 149 control participants were included in the study. For all participants, clinical risk factors, smoking status, and other demographic data were recorded from ...
Osada Makoto - - 2012
We retrospectively studied 89 patients with chronic hepatitis C virus (HCV) infection, including 50 chronic hepatitis (CH) cases, 18 liver cirrhosis (LC) cases, and 21 LC with hepatocellular carcinoma (LC + HCC) cases, with regard to various factors related with thrombocytopenia. The platelet count decreased with the stage advancement of ...
Udenigwe Chibuike C - - 2012
The aim of this work was to determine the multifunctional properties of flaxseed protein-derived cationic peptide fractions. Alcalase hydrolysis of flaxseed protein fractions liberated cationic peptides, which were separated into two major fractions (FI and FII) by chromatography using a cation-exchange column. Due to their cationic property, the peptide fractions ...
Visser Els - - 2012
To identify women who are suffering from urinary incontinence but do not consult a physician and to identify reasons for this. Survey study as part of a randomized controlled trial that investigates the effects of a standardized assessment and evidence-based treatment on urinary incontinence in older women, the URINO project. ...
Wang Mei Jiao - - 2012
Prohibitin is a highly conserved major sperm mitochondrial membrane protein whose absence in somatic cells is associated with mitochondrial membrane depolarization and increased generation of reactive oxygen species (ROS). Our recent findings suggest that high levels of oxidants in human semen may contribute to male infertility and that sperm motility ...
Scaini Giselli - - 2012
Maple syrup urine disease is an inherited metabolic disease predominantly characterized by neurological dysfunction. However, the mechanisms underlying the neuropathology of this disease are still not defined. Therefore, the aim of this study was to investigate the effect of acute and chronic administration of a branched-chain amino acids (BCAA) pool ...
Agrawal Mukesh - - 2012
This study reports on a facile and versatile approach for modification of macroscopic surface via grafting of multifunctional poly(2-oxazoline) molecules in brush-like conformation. For this purpose, carboxyl-terminated poly(2-isopropyl-2-oxazoline) molecules have been synthesized by ring opening cationic polymerization and subsequently grafted on underlined substrates by exploiting the "grafting to" approach. A ...
Low Kathryn Graff - - 2012
BACKGROUND: Obesity has reached epidemic proportions in the USA and is a particular threat to those with coronary disease. Motivational interviewing (MI) is a client-centered, directive method for enhancing intrinsic motivation to change by exploring and resolving ambivalence about altering behavior. PURPOSE: This study examined the efficacy of MI compared ...
Nechvatalova Jana - - 2012
INTRODUCTION: Selective deficiency IgA (IgAD) is the most common primary abnormality of immunoglobulin production with unknown pathophysiology. It is genetically related to common variable immunodeficiency (CVID), where besides IgA also IgG and frequently IgM serum levels are decreased. In this study we focused on determination of B-lymphocyte developmental stages and ...
Choe Dong-Hwan - - 2012
Here, we describe a novel method for the extraction of insect cuticular hydrocarbons using silica gel, herein referred to as "silica-rubbing". This method permits the selective sampling of external hydrocarbons from insect cuticle surfaces for subsequent analysis using gas chromatography-mass spectrometry (GC-MS). The cuticular hydrocarbons are first adsorbed to silica ...
Jovanović Mirjana - - 2012
Purpose: To assess health-related quality of life (HRQOL) in adults with spinal cord injury (SCI), muscular dystrophy (MD), multiple sclerosis (MS), and cerebral palsy (CP). Methods: This is a multicenter, community-based, cross-sectional study of adults diagnosed with CP (94), MD (99), MS (98), SCI (99), and healthy adults (105). The ...
Raza Abida - - 2012
Hepatitis C virus (HCV) quantification is used as a prognostic marker for treatment success. In a routine clinical laboratory some infinitesimal sample handling factors can contribute to variability and loss of precision in HCV quantification. This may include blood collection tubes, blood drawing procedure, sample processing and storage temperatures. In ...
Nijs Jo - - 2012
Purpose: Kinesiophobia and catastrophizing are frequent among people with chronic fatigue syndrome (CFS). This study was aimed at examining (1) whether kinesiophobia, anticipated symptoms and fatigue catastrophizing are related to stair climbing performance in people with CFS; and (2) whether kinesiophobia and fatigue catastrophizing are related to daily physical activity ...
Carey Satterfield M - - 2012
The global incidence of human obesity has more than doubled over the past three decades. An ovine model of obesity was developed to determine effects of maternal obesity and arginine supplementation on maternal, placental, and fetal parameters of growth, health, and well being. One-hundred-twenty days prior to embryo transfer, ewes ...
Kendziorek Maria - - 2012
Wheat (Triticum aestivum L.) seedlings contain four alanine aminotransferase (AlaAT) homologues. Two of them encode AlaAT enzymes, whereas two homologues act as glumate:glyoxylate aminotransferase (GGAT). To address the function of the distinct AlaAT homologues a comparative examination of the changes in transcript level together with the enzyme activity and alanine ...
Valocik Gabriel - - 2012
The aim of our study was to assess the diagnostic accuracy of a global longitudinal strain and strain rate (GLS, GLSR) and mean radial strain and strain rate (MRS, MRSR) of the left ventricle to predict multivessel disease. In 113 patients, who underwent coronary angiography, left ventricular deformation was analysed ...
He Mingyang - - 2012
Downy mildew, caused by the oomycete Plasmopara viticola, is a serious fungal disease in the cultivated European grapevines (Vitis vinifera L.). The class 10 of pathogenesis-related (PR) genes in grapevine leaves was reported to be accumulated at mRNA level in response to P. viticola infection. To elucidate the functional roles ...
Keller Tracy L TL Department of Developmental Biology, Harvard School of Dental Medicine, Boston, Massachusetts, USA. - - 2012
Febrifugine, the bioactive constituent of one of the 50 fundamental herbs of traditional Chinese medicine, has been characterized for its therapeutic activity, though its molecular target has remained unknown. Febrifugine derivatives have been used to treat malaria, cancer, fibrosis and inflammatory disease. We recently demonstrated that halofuginone (HF), a widely ...
Lu Jimmy C - - 2012
Left ventricular systolic function is an important indicator of clinical well-being and outcomes for patients with repaired tetralogy of Fallot (TOF). This study tested the hypothesis that left ventricular diastolic function by pulsed-wave tissue Doppler is associated with quality of life in this population. In this study, 38 subjects (age, ...
Nguyen Tuan M - - 2012
Escherichia coli must be able to survive extreme acidic conditions. We were interested in determining the role of the inner membrane protein YhiM in survival in acidic conditions. Previous data demonstrated that the yhiM gene was upregulated in acidic conditions (Tucker et al. in J Bacteriol. 184:6551-6558, 2002). We therefore ...
Wang Yan-Ting - - 2012
Spermiogenesis is a developmental process undergoing continuous differentiation to drive a diploid spermatogonium towards a haploid sperm cell. This striking transformation from spermatogonium to spermatozoa is made possible by the stage-specific adaption of cytoskeleton and associated molecular motor proteins. KIFC1 is a C-terminal kinesin motor found to boast essential roles ...
Chen Guoqiang - - 2012
Objective: To investigate the effects of different aminoglycoside antibiotics on platelet aggregation and blood coagulation, as well as the underlying mechanisms. Method: Blood samples were collected and prepared as platelet-rich plasma and platelet-poor plasma samples. Then assigned into different groups for the following antibiotics treatments: gentamicin, streptomycin, etimicin, amikacin, and ...
Scheel M - - 2012
BACKGROUND: Diffusion Tensor Imaging studies have repeatedly shown a decrease of the fractional anisotropy (FA) parameter in patients with schizophrenia. This has been interpreted as a disturbed microstructural integrity of white matter. However, FA is a relative parameter that is derived from eigenvalues of the diffusion tensor and FA reductions ...
Mei Dan - - 2012
Many studies have demonstrated that Mrp2 is highly regulated in some physiopathological situations. The aim of this study was to investigate effects of diabetes mellitus on function and expression of multidrug resistance-associated protein 2 (Mrp2) in rat liver, kidney and intestine. Diabetic rats were induced by an intraperitoneal administration of ...
Chen Su - - 2012
TaLEA (Tamarix androssowii late embryogenesis abundant gene, DQ663481) gene was introduced into Populus simonii × Populus nigra by Agrobacterium tumefaciens-mediated transformation with the aim of improving salt-tolerance. Among the 15 transgenic lines, one showed a dwarf phenotype (dwf1). Under the same growth conditions, dwf1 height was significantly reduced compared with the wild-type ...
Fritzsche K - - 2012
The great physical resemblance between epileptic and dissociative seizures and a diagnosis of epilepsy that had been made years ago and usually had been treated unsuccessfully makes it difficult for both physician and patient to communicate the diagnosis of dissociative seizures. A direct referral to psychotherapy treatment is rarely accepted ...
Çakarer Sirmahan - - 2013
This study evaluated the early hemostatic effects of a novel hemostatic agent (Ankaferd blood stopper [ABS]) during dental extractions in patients on antithrombotic therapy, without interruption or diminution of the medication. In total, 25 patients, who are on antithrombotic therapy and in need of simple dental extractions, were randomized into ...
Skorski Tomasz - - 2012
The BCR-ABL1 oncogenic tyrosine kinase can transform pluripotent hematopoietic stem cells and initiate chronic myeloid leukemia in chronic phase (CML-CP), a myeloproliferative disorder characterized by excessive accumulation of mature myeloid cells. Patients in CML-CP usually respond to treatment with ABL1 tyrosine kinase inhibitors (TKIs) such as imatinib, though some patients ...
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