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Results 501 - 550 of 2852
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Dababneh Haitham - - 2012
The overall incidence of neurological complications due to infective endocarditis is as high as 40%, with embolic infarcts more common than hemorrhagic strokes. The standard of care for typical strokes does not apply to infective endocarditis because there is a substantial risk of hemorrhage with thrombolysis. In the last decade ...
Zallat Jihad - - 2012
We present a new method that allows efficient spectral calibration for a polarization state analyzer. The procedure does not require any additional polarization optical element other than the polarization state analyzer itself. It uses a double-pass technique that can be achieved up to a very good precision. The method is ...
Ong M W S - - 2012
This review investigates the effectiveness of ablative and non-ablative Fractional Photothermolysis (FP) lasers for treating facial acne scars. 26 studies (13=ablative FP; 13=non-ablative FP) published between year-2003 to January 2011 were reviewed. Quantitative and qualitative data from each article were examined and analysed. 4 studies were split-face randomised controlled studies ...
Berrout Jonathan - - 2012
The TRPV4 Ca(2+)-permeable channel is sensitive to mechanical stimuli. In the current study we have employed immunocytochemical staining in kidney slices and functional assessments (Ca(2+) imaging) in isolated, split-opened, tubule segments to define TRPV4 sites of expression and flow-dependent function in the collecting duct system. Staining patterns revealed strong expression ...
Zhang Donglu - - 2012
A drug candidate, BMS-A ((N-(4-((1H-pyrrolo[2,3-b]pyridin-4-yl)oxy)-3-fluorophenyl)-1-(4-fluorophenyl) 2-oxo-1,2-dihydropyridine- 3-carboxamide)), was associated with dose- and time-dependent vacuolar degeneration and necrosis of the adrenal cortex following oral administration to rats. Pretreatment with 1-aminobenzotriazole (ABT), a non-specific P450 inhibitor, ameliorated the toxicity. In vivo and in vitro systems, including adrenal cortex-derived cell lines, were used ...
Nakamura Tadashi - - 2012
In the present study we examined the protective effect of Brazilian propolis against hepatic oxidative damage in rats with water-immersion restraint stress (WIRS) in comparison with that of vitamin E (VE). Fasted rats orally received Brazilian green propolis ethanol extract (BPEE; 10, 50 or 100 mg/kg), VE (250 mg/kg) or vehicle at ...
Kwon Na Young - - 2012
A new concept for rapid, label-free cysteine sensing method is proposed via possible naked eye-detection of red-to-blue emission color change. Intermolecular exciton migration in conjugated polyelectrolyte-based assay complex is adopted to enhance selectivity and sensitivity for cysteine sensing by formation and dissociation of polymer-Hg2+-thymine assay complex in the absence and ...
Afewerki Samson - - 2012
The first direct intermolecular regiospecific and highly enantioselective α-allylic alkylation of linear aldehydes by a combination of achiral bench-stable Pd(0) complexes and simple chiral amines as co-catalysts is disclosed. The co-catalytic asymmetric chemoselective and regiospecific α-allylic alkylation reaction is linked in tandem with in situ reduction to give the corresponding ...
Matesanz Ruth - - 2012
The most common mode of bacterial resistance to aminoglycoside antibiotics is the enzyme-catalysed chemical modification of the drug. Over the last two decades, significant efforts in medicinal chemistry have been focused on the design of non- inactivable antibiotics. Unfortunately, this strategy has met with limited success on account of the ...
Reinsch Brian Carl - - 2012
Sulfidation of metallic nanoparticles such as silver nanoparticles (AgNPs) released to the environment may be an important detoxification mechanism. Two types of AgNPs - an engineered polydisperse and aggregated AgNP powder, and a laboratory-synthesized, relatively monodisperse AgNP aqueous dispersion - were studied. The particles were sulfidated to varying degrees and ...
Chen Zhang-Hui - - 2012
BACKGROUND: Circulating microRNA (miRNAs) have been shown to have the potential as noninvasive diagnosis markers in several types of cancers. In this study, we investigated whether circulating miRNAs could be used in the diagnosis of prostate cancer (CaP) in a Chinese patient population. METHODS: Illumina's Human v2 miRNA microarray was ...
Rapoport Mark J - - 2012
It is important for clinicians to recognize major depression following traumatic brain injury (TBI) because of its association with poor global and psychosocial outcome, postconcussive symptoms and cognitive deficits. The purpose of this review is to provide an up-to-date selective review of the current understanding of epidemiology, risk factors and ...
Gelkopf Marc - - 2012
ABSTRACT: People with schizophrenia are more likely to smoke, and to smoke more frequently, than those without schizophrenia. Furthermore, inpatients smoke even more frequently compared with those living in the community. In light of this, we implemented and assessed a smoking reduction intervention using a wide array of behavioral group ...
van den Bosch T - - 2012
We evaluated the implementation of a strict procedure for endometrium biopsy, including pre-sampling ultrasound examination and assessment of the tissue yield during sampling, in 257 consecutive women with abnormal bleeding. The tissue yield was assessed during sampling and scored from 1 to 4. The median endometrial thickness as measured by ...
Guan Binbin - - 2012
This Letter demonstrates a measurement technique based on frequency-to-time mapping and coherent detection, which enables the complete (i.e., amplitude and phase) characterization of dynamically reconfigurable photonic filters. We apply this technique to a unit cell from a silicon CMOS-compatible photonic lattice filter that has a rapidly changing transfer function with ...
Chaswal V - - 2012
The development and application of an automated 3D greedy heuristic (GH) optimization algorithm utilizing the adjoint sensitivity fields for treatment planning to assess the advantage of directional interstitial prostate brachytherapy is presented. Directional and isotropic dose kernels generated using Monte Carlo simulations based on Best Industries model 2301 I-125 source ...
Moyle-Heyrman Georgette - - 2012
The TATA box binding protein (TBP) is a central component of the transcription preinitiation complex, and its occupancy at a promoter is correlated with transcription levels. The TBP-promoter DNA complex contains sharply bent DNA and its interaction lifetime is limited by the ATP-dependent TBP displacement activity of the Snf2/Swi2 ATPase ...
Houben Katrijn - - 2012
Aims Previous research showed that consistently not responding to alcohol-related stimuli in a Go/No-Go training reduces drinking behavior. This study aimed to further examine the mechanisms underlying this Go/No-Go training effect. Design, setting, and participants Fifty-seven heavy drinkers were randomly assigned to two training conditions: In the beer/no-go condition, alcohol-related ...
Wark Peter - - 2012
© 2012 The Author. Respirology © 2012 Asian Pacific Society of Respirology.
Damen Bram - - 2012
Arabinoxylan oligosaccharides (AXOS) are studied as food compounds with prebiotic potential. Here, the impact of consumption of breads with in situ-produced AXOS on intestinal fermentation and overall gastrointestinal characteristics was evaluated in a completely randomized, double-blind, controlled, cross-over study. Twenty-seven healthy volunteers consumed 180 g of wheat/rye bread with or ...
Loscha Karin V - - 2012
A cell-free protein synthesis system from which the release factor RF1 has been selectively removed enables the facile incorporation of unnatural amino acids into proteins at difficult and multiple sites by optimized use of orthogonal tRNA/aminoacyl-tRNA synthetase systems. (19) F NMR spectroscopy of a protein labeled combinatorially with trifluoromethyl phenylalanine ...
Bhunia Sabyasachi - - 2012
Golden tendencies: The title reaction for synthesizing cyclopentenone derivatives utilizes a gold complex and 8-methylquinoline oxide as catalytic system (see scheme; IPr=1,3-bis(diisopropylphenyl)imidazol-2-ylidene). Such products are not attainable using diazocarbonyl reagents as the gold carbenoids tend towards reacting with CH bonds.
Bezkorovaynaya Olga - - 2012
A bottom-up coarse-graining procedure for peptides in aqueous solution is presented, where the interactions in the coarse-grained (CG) model are determined such that the CG peptide samples conformations according to a high-resolution (atomistic) model. It is shown that important aspects of conformational sampling, such as correlated degrees of freedom (DOF) ...
Lai Grace - - 2012
Despite language disabilities in autism, music abilities are frequently preserved. Paradoxically, brain regions associated with these functions typically overlap, enabling investigation of neural organization supporting speech and song in autism. Neural systems sensitive to speech and song were compared in low-functioning autistic and age-matched control children using passive auditory stimulation ...
Truong Phuoc Long - - 2012
We report a simple, ultra-sensitive, and straightforward method for non-labeling detection of a cancer biomarker, using Rayleigh light scattering spectroscopy of the individual nanosensor based on antibody-antigen recognition and localized surface plasmon resonance (LSPR) λ(max) shifts. By experimentally measuring the refractive index sensitivity of Au nanorods, the Au nanorod with ...
Zakareia Faten Abdulhady - - 2012
Aims: Progressive vasodegeneration in microvascular beds is the major underlying factor in initiation and progression of diabetic complications. Chemerin shows a strong correlation with various facets of the metabolic syndrome, which is associated with dysregulated angiogenesis. VEGF is shown to have an angiogenic role in certain cardiovascular risk factors, including ...
Li Yunqing Y Hugo W Moser Research Institute at Kennedy Krieger, and Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA. - - 2012
The origins of tumor-propagating neoplastic stem-like cells [cancer stem cells (CSC)] and their relationship to the bulk population of tumor cells that lack stem-like tumor-propagating features (i.e., transit-amplifying cancer progenitor cells) remain unclear. Recent findings from multiple laboratories show that cancer progenitor cells have the capacity to dedifferentiate and acquire ...
Al-Holou Wajd N - - 2012
Object This study was undertaken to define the age-related prevalence of cavernous malformations (CMs) in children and young adults undergoing intracranial imaging. In addition, the authors aim to clarify the natural history of CMs in young people, especially in those with incidentally discovered lesions. Methods To identify those patients with ...
Fitzgerald Oliver - - 2012
Biomarkers may be used to screen patients with psoriasis for psoriatic arthritis (PsA) and to assess disease activity and severity. Candidate biomarkers should fulfil the key features of the OMERACT (Outcome Measures in Rheumatology) filter, that is, truth, discrimination, and feasibility. A number of biomarkers are currently being investigated in ...
Araujo Júnior Edward - - 2012
Objectives- The purpose of this study was to determine reference values for the length and area of the fetal corpus callosum between 20 and 33 weeks' gestation using 3-dimensional sonography. Methods- A cross-sectional study was performed in 293 healthy pregnant women between 20 and 33 weeks' gestation. The length and ...
Starr Rebecca - - 2012
A common task in microscopy is to fit an image of a fluorescent probe to a point spread function (PSF) in order to estimate the position of the probe. The PSF is often approximated as a Gaussian for mathematical simplicity. We show that the separable property of the Gaussian PSF ...
Khan Faiz Ahmed - - 2012
Total synthesis of the published structure of amathamide D is described. Methyl 2,3,4-tribromo-5-hydroxybenzoate was selected as starting compound since it is readily accessible via acid mediated Grob fragmentation-aromatization reaction of 1,4,5,6-tetrabromo-7,7-dimethoxybicyclo[2.2.1]hept-5-en-2-one. The aforementioned ester was transformed into reported structure of amathamide D through methylation of hydroxyl group and converting the ...
Seike Koji - - 2012
Although the deep sea is the largest ecosystem on Earth, its infaunal ecology remains poorly understood because of the logistical challenges. Here we report the morphology of relatively large burrows obtained by in situ burrow casting at a hydrocarbon-seep site and a non-seep site at water depths of 1173 and ...
Marcos Ricardo R Laboratory of Histology and Embryology, Institute of Biomedical Sciences Abel Salazar, University of Porto, - - 2012
Stereology offers a number of tools for the analysis of sections in microscopy (which usually provide only two-dimensional information) for the purpose of estimating geometric quantities, such as volume, surface area, length or number of particles (cells or other structures). The use of these tools enables recovery of the three-dimensional ...
Hasenbach Kathy - - 2012
Intracerebral experimental gliomas attract intravenously injected murine or human bone marrow-derived hematopoietic progenitor and stem cells (HPC) in vitro, ex vivo, and in vivo, indicating that these progenitor cells might be suitable vehicles for a cell-based delivery of therapeutic molecules to malignant gliomas. With regard to therapeutic application, it is ...
Ross J D - - 2012
ACCESSIBLE SUMMARY: •  Nurse prescribing was launched in the UK in the 1990s, but was introduced to psychiatric/mental health nursing within the last 7 years. Information is available about nurse prescribing in general practice and adult nursing, but there is little research relating to mental health. Most mental health nurses ...
Tanaka Hirokazu - - 2012
When subjects adapt their reaching movements in the setting of a systematic force or visual perturbation, generalization of adaptation can be assessed psychophysically in two ways: by testing untrained locations in the work space at the end of adaptation (slow postadaptation generalization) or by determining the influence of an error ...
Nandasena Sumal S Evaluation and Research Unit, National Institute of Health Sciences, Ministry of Health, Kalutara, Sri Lanka. - - 2012
Health effects due to air pollution is becoming a major public health problem with growing traffic congestion and establishment of small- to medium-scale industries with poor emission controls in urban cities of Sri Lanka. Respiratory health status of 7- to 10-year-old children in two settings (urban and semi-urban) was assessed ...
Saga Hirohisa - - 2012
Camalexin is the major phytoalexin in Arabidopsis. Almost a complete set of camalexin biosynthetic enzymes have been elucidated, but only limited information is available regarding molecular mechanisms regulating camalexin biosynthesis. Here, we demonstrate ANAC042, a member of NAC transcription factor family genes, is involved in camalexin biosynthesis induction. T-DNA insertion ...
Chan Jefferson - - 2012
A series of isotopically labeled natural substrate analogues (phenyl 5-N-acetyl-α-D-neuraminyl-(2-->3)-β-D-galactopyranosyl-(1-->4)-1-thio-β-D-glucopyranoside; Neu5Acα2,3LacβSPh, and the corresponding 2-->6 isomer) were prepared chemoenzymatically in order to characterize, by use of multiple kinetic isotope effect (KIE) measurements, the glycosylation transition states for Vibrio cholerae sialidase-catalyzed hydrolysis reactions. The derived KIEs for Neu5Acα2,3LacβSPh for the ring ...
Muñana K R - - 2012
BACKGROUND: There is little evidence-based information available to guide treatment of refractory epilepsy in dogs. The antiepileptic drug levetiracetam (LEV) is administered to dogs, although its safety and efficacy are unknown. OBJECTIVE: To evaluate the safety and efficacy of LEV as adjunctive therapy for refractory epilepsy in dogs. ANIMALS: Thirty-four ...
Perez-Rojas Evelyn - - 2012
Interventional radiology procedures treat a variety of solid tumor malignancies. Transarterial chemoembolization (TACE) is a minimally invasive procedure performed under fluoroscopic guidance that is used in treatment of hepatic malignancies because of hepatocellular carcinoma or malignancy that has metastasized to the liver. Patients undergoing a TACE procedure may manifest postembolization ...
Colvin Alexis Chiang - - 2012
Recent publications suggest that arthroscopic and open rotator cuff repairs have had comparable clinical results, although each technique has distinct advantages and disadvantages. National hospital and ambulatory surgery databases were reviewed to identify practice patterns for rotator cuff repair. The rates of medical visits for rotator cuff pathology, and the ...
Oluigbo Chima O - - 2012
The goal of this study was to compare clinical outcomes following decompressive craniectomy performed for intracranial hypertension in children with nonaccidental, blunt cranial trauma with outcomes of decompressive craniectomy in children injured by other mechanisms. All children in a prospectively acquired database of trauma admissions who underwent decompressive craniectomy over ...
Yuan Wei-Hsin - - 2012
Objectives- This study aimed to report the differences in sonographic features of ruptured and unruptured epidermal cysts. Methods- We reviewed and analyzed the sonographic features of superficial epidermal cysts of in 2 subgroups of 46 patients: 20 with ruptured cysts and 26 with unruptured cysts. All lesions were diagnosed either ...
Renard William - - 2012
We report on an all single-mode master oscillator power fiber amplifier delivering high energy picosecond solitons at 1960 nm. The Bragg stabilized and self-starting oscillator delivers 62 pJ transform-limited pulses at 11.2 MHz pulse repetition frequency. Solitons are amplified in a core-pumped single-mode heavily thulium-doped fiber up to 26 nJ. ...
Chalhoub S - - 2012
Anemia is present in 30-65% in cats with chronic kidney disease (CKD) and few long-term treatment options exist. Darbepoetin is effective in treating anemia of kidney disease in humans and may be used in cats. To evaluate the use of darbepoetin, a recombinant analog of human erythropoietin, to stimulate erythropoiesis, ...
Qiu Ri - - 2012
One-dimensional ferromagnetic iron dendritic wire array film is prepared by facile electrodeposition. The space hindrance effect caused by neighbouring crystals resists the free growth directions parallel to the substrate, which is considered as a possible growth mechanism of one-dimensional morphology. Dendritic iron wire can be transformed into α-Fe(2)O(3) without destroying ...
Soares Ana Raquel - - 2012
Prenatal exposure to ethanol leads to a myriad of developmental disorders known as fetal alcohol spectrum disorder, often characterized by growth and mental retardation, central nervous system damage and specific craniofacial dysmorphic features. The mechanisms of ethanol toxicity are not fully understood, but exposure during development affects the expression of ...
Forsberg Maud - - 2012
Heparan sulfate proteoglycans, present on cell surfaces and in the extracellular matrix, interact with growth factors and morphogens to influence growth and differentiation of cells. The sulfation pattern of the heparan sulfate chains formed during biosynthesis in the Golgi compartment will determine the interaction potential of the proteoglycan. The glucosaminyl ...
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